Colocalization of serotonin receptor subtypes 5-HT2A, 5-HT2C, and 5-HT6 with neuropeptides in rat striatum

Journal of Comparative Neurology

Volumn 370, Issue 3, 1996, Pages 405-414

  Ward, Raymond P ^a,b   Dorsa, Daniel M ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

basal ganglia; dynorphin; enkephalin; in situ hybridization; substance p

Indexed keywords

DYNORPHIN; ENKEPHALIN; MESSENGER RNA; NEUROPEPTIDE; RECEPTOR SUBTYPE; SEROTONIN 1C RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN RECEPTOR; SUBSTANCE P;

ANIMAL TISSUE; ARTICLE; BASAL GANGLION; CONTROLLED STUDY; CORPUS STRIATUM; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; TISSUE DISTRIBUTION;

ANIMALS; CORPUS STRIATUM; DYNORPHINS; ENKEPHALINS; MALE; NEURAL PATHWAYS; NEUROPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SUBSTANCE P;

EID: 0030018405     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19960701)370:3<405::AID-CNE10>3.0.CO;2-R     Document Type: Article

References (44)

1. Augood, S.J. and P.C. Emson (1994) Adenosine A2a receptor mRNA is expressed by enkephalin cells but not by somatostatin cells in rat striatum: A co-expression study. Brain Res. Mol. Brain Res. 22:204-210.
2. Barakat Walter, I., H.U. Affolter, and B. Droz (1991) Expression of substance P and preprotachykinin mRNA by primary sensory neurons in culture: Regulation by factors present in peripheral and central target tissues. Brain Res. Mol. Brain Res. 10:107-114.
3. Beschert, U., D.A. Amara, L. Segu, and H. Hen (1994) The mouse 5-hydroxytryptamine1B receptor is localized predominantly on axon terminals. Neuroscience 58:167-182
4. Bruinvels, A.T., B. Landwehrmeyer, E.L. Gustafson, M.M. Durkin, G. Mengod, T.A. Branchek, D. Hoyer, and J.M. Palacios (1994) Localization of 5-HT1B, 5-HT1D alpha, 5-HT1E and 5-HT1F receptor messenger RNA in rodent and primate brain. Neuropharmacology 33:367-386.
5. Buchsbaum, M.S. (1990) The frontal lobes, basal ganglia, and temporal lobes as sites for schizophrenia. Schizophr. Bull. 16:379-389.
6. Civelli, O., J. Douglass, A. Goldstein, and E. Herbert (1985) Sequence and expression of the rat prodynorphin gene. Proc. Natl. Acad. Sci. U.S.A. 82:4291-4295.
7. Fishell, G. and D. van der Kooy (1987) Pattern formation in the striatum: Developmental changes in the distribution of striatonigral neurons. J. Neurosci. 7:1969-1978.
8. Garlow, S.J., D.A. Morilak, R.R. Dean, B.L. Roth, and R.D. Ciaranello (1993) Production and characterization of a specific 5-HT2 receptor antibody. Brain Res. 615:113-120.
9. Gerald, C., N. Adham, H.T. Kao, M.A. Olsen, T.M. Laz, L.E. Schlechter, J.A. Bard, P.J. Vaysse, P.R. Hartig, and T.A. Branchek (1995) The 5-HT4 receptor: Molecular cloning and pharmacological characterization of two splice variants. Embo J. 14:2806-2815.
10. Gerfen, C.R. (1992) The neostriatal mosaic: Multiple levels of compartmental organization in the basal ganglia. Annu. Rev. Neurosci. 15:285-320.
11. Gerfen, C.R., T.M. Engber, L.C. Mahan, Z. Susel, T.N. Chase, F.J. Monsma, Jr., and D.R. Sibley (1990) D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science 250:1429-1432.
12. Gerfen, C.R., J.F. McGinty, and W.S.d. Young (1991) Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: In situ hybridization histochemical analysis. J. Neurosci. 11:1016-1031.
13. Gerfen, C.R. and W.S.d. Young (1988) Distribution of striatonigral and striatopallidal peptidergic neurons in both patch and matrix compartments: An in situ hybridization histochemistry and fluorescent retrograde tracing study. Brain Res. 460:161-167.
14. Haber, S.N. and W.J. Nauta (1983) Ramifications of the globus pallidus in the rat as indicated by patterns of immunohistochemistry. Neuroscience 9:245-260.
15. Harlan, R.E., M.M. Garcia, and J.E. Krause (1989) Cellular localization of substance P- and neurokinin A-encoding preprotachykinin mRNA in the female rat brain. J. Comp. Neurol. 287:179-212.
16. Harrison, M.B., R.G. Wiley, and G.F. Wooten (1990) Selective localization of striatal D1 receptors to striatonigral neurons. Brain Res. 528:317-322.
17. Hellendall, R.P., U.B. Schambra, J.P. Liu, and J.M. Lauder (1993) Prenatal expression of 5-HT1C and 5-HT2 receptors in the rat central nervous system. Exp. Neurol. 120:186-201.
18. Hoyer, D., D.E. Clarke, J.R. Fozard, P.R. Hartig, G.R. Martin, E.J. Mylecharane, P.R. Saxena, and P.P. Humphrey (1994) International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin). Pharmacol. Rev. 46:157-203.
19. Jakeman, L.B., Z.P. To, R.M. Eglen, E.H. Wong, and D.W. Bonhaus (1994) Quantitative autoradiography of 5-HT4 receptors in brains of three species using two structurally distinct radioligands, [3H]GR113808 and [3H]BIMU-1. Neuropharmacology 33:1027-1038.
20. Julius, D., A.B. MacDermott, R. Axel, and T.M. Jessell (1988) Molecular characterization of a functional cDNA encoding the serotonin 1c receptor. Science 247:558-564.
21. Kondo, Y., N. Ogawa, M. Asanuma, H. Hirata, K. Tanaka, Y. Kawada, and A. Mori (1993) Regional changes in neuropeptide levels after 5,7-dihydroxytryptamine-induced serotonin depletion in the rat brain. J. Neural Transm. Gen. Sect. 92:151-157.
22. Le Moine, C., E. Normand, and B. Bloch (1991) Phenotypical characterization of the rat striatal neurons expressing the D1 dopamine receptor gene. Proc. Natl. Acad. Sci. U.S.A. 88:4205-4209.
23. Le Moine, C., E. Normand, A.F. Guitteny, B. Fouque, R. Teoule, and B. Bloch (1990) Dopamine receptor gene expression by enkephalin neurons in rat forebrain. Proc. Natl. Acad. Sci. U.S.A. 87:230-234.
24. Lester, J., S. Fink, N. Aronin, and M. DiFiglia (1993) Colocalization of D1 and D2 dopamine receptor mRNAs in striatal neurons. Brain Res. 627:106-110.
25. Loopuijt, L.D. and D. van der Kooy (1985) Organization of the striatum: Collateralization of its efferent axons. Brain Res. 348:86-99.
26. Matsubara, S., R. Matsubara, I. Kusumi, T. Koyama, and I. Yamashita (1993) Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo. J. Pharmacol. Exp. Ther. 265:498-508.
27. Meltzer, H.Y. (1992) The importance of serotonin-dopamine interactions in the action of clozapine. Br. J. Psychiatry Suppl. 17:22-29.
28. Mengod, G., M. Pompeiano, M.I. Martinez Mir, and J.M. Palacios (1990) Localization of the mRNA for the 5-HT2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites. Brain Res. 524:139-143.
29. Merchenthaler, I., D.E. Lennard, P. Cianchetta, A. Merchenthaler, and D. Bronstein (1995) Induction of proenkephalin in tuberoinfundibular dopaminergic neurons by hyperprolactinemia: The role of sex steroids. Endocrinology 136:2442-2450.
30. Miller, M.A., P.E. Kolb, and M.A. Raskind (1993) A method for simultaneous detection of multiple mRNAs using digoxigenin and radioisotopic cRNA probes. J. Histochem. Cytochem. 41:1741-1750.
31. Monsma, F.J., Jr., Y. Shen, R.P. Ward, M.W. Hamblin, and D.R. Sibley (1993) Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol. Pharmacol. 43:320-327.
32. Morilak, D.A., S.J. Garlow, and R.D. Ciaranello (1993) Immunocytochemical localization and description of neurons expressing serotonin2 receptors in the rat brain. Neuroscience 54:701-717.
33. Morris, B.J., A. Herz, and V. Hollt (1989) Localization of striatal opioid gene expression, and its modulation by the mesostriatal dopamine pathway: An in situ hybridization study. J. Mol. Neurosci. 1:9-18.
34. Numan, S., K.H. Lundgren, D.E. Wright, J.P. Herman, and K.B. Seroogy (1995) Increased expression of 5HT2 receptor mRNA in rat striatum following 6-OHDA lesions of the adult nigrostriatal pathway. Mol. Brain Res. 29:391-396.
35. Paxinos, G. and C. Watson, (1986) The Rat Brain in Stereotaxic Coordinates. Orlando, Florida: Academic Press, Inc.
36. Pollack, A.E., M.B. Harrison, G.F. Wooten, and J.S. Fink (1993) Differential localization of A2a adenosine receptor mRNA with D1 and D2 dopamine receptor mRNA in striatal output pathways following a selective lesion of striatonigral neurons. Brain Res. 631:161-166.
37. Pompeiano, M., J.M. Palacios, and G. Mengod (1994) Distribution of the serotonin 5-HT2 receptor family mRNAs: Comparison between 5-HT2A and 5-HT2C receptors. Brain Res. Mol. Brain Res. 23:163-178.
38. Roth, B.L., S.C. Craigo, M.S. Choudhary, A. Uluer, F.J. Monsma, Jr., Y. Shen, H.Y. Meltzer, and D.R. Sibley (1994) Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J. Pharmacol. Exp. Ther. 268:1403-1410.
39. See, R.E. and M.A. Chapman (1994) The consequences of long-term antipsychotic drug administration on basal ganglia neuronal function in laboratory animals. Crit. Rev. Neurobiol. 8:85-124.
40. Vincent, S.R., T. Hokfelt, I. Christensson, and L. Terenius (1982) Dynorphin-immunoreactive neurons in the central nervous system of the rat. Neurosci. Lett. 33:185-190.
41. Waeber, C., M. Sebben, A. Nieoullon, J. Bockaert, and A. Dumuis (1994) Regional distribution and ontogeny of 5-HT4 binding sites in rodent brain. Neuropharmacology 33:527-541.
42. Walker, P.D., L.A. Riley, R.P. Hart, and G.M. Jonakait (1991) Serotonin regulation of tachykinin biosynthesis in the rat neostriatum. Brain Res. 546:33-39.
43. Ward, R.P., M.W. Hamblin, J.E. Lachowicz, B.J. Hoffman, D.R. Sibley, and D.M. Dorsa (1995) Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry. Neuroscience 64:1105-1111.
44. Yoshikawa, K., C. Williams, and S.L. Sabol (1984) Rat brain preproenkephalin mRNA. cDNA cloning, primary structure, and distribution in the central nervous system. J. Biol. Chem. 259:14301-14308.