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Volumn 23, Issue 4, 2004, Pages 231-258

Application of proteomics technologies in the investigation of the brain

Author keywords

Brain; Mass spectrometry; Neurological diseases; Proteomics; Two dimensional protein database

Indexed keywords

BIOMARKERS; DATABASE SYSTEMS; DISEASES; GENES; LIVING SYSTEMS STUDIES; MASS SPECTROMETRY; NEUROLOGY; PROTEINS;

EID: 3042554008     PISSN: 02777037     EISSN: None     Source Type: Journal    
DOI: 10.1002/mas.10075     Document Type: Review
Times cited : (116)

References (150)
  • 1
    • 0037434994 scopus 로고    scopus 로고
    • Constellations in a cellular universe
    • Aebersold R. 2003. Constellations in a cellular universe. Nature 422:115-116.
    • (2003) Nature , vol.422 , pp. 115-116
    • Aebersold, R.1
  • 2
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics
    • Aebersold R, Mann M. 2003. Mass spectrometry-based proteomics. Nature 422:198-207.
    • (2003) Nature , vol.422 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 3
    • 0034054368 scopus 로고    scopus 로고
    • Cancer proteomics: From identification of novel markers to creation of artifical learning models for tumor classification
    • Alaiya AA, Franzén B, Auer G, Linder S. 2000. Cancer proteomics: From identification of novel markers to creation of artifical learning models for tumor classification. Electrophoresis 21:1210-1217.
    • (2000) Electrophoresis , vol.21 , pp. 1210-1217
    • Alaiya, A.A.1    Franzén, B.2    Auer, G.3    Linder, S.4
  • 4
    • 0032127166 scopus 로고    scopus 로고
    • 10 Years of genomics, chromosome 21, and down syndrome
    • Antonarakis SE. 1998. 10 Years of genomics, chromosome 21, and Down syndrome. Genomics 51:1-16.
    • (1998) Genomics , vol.51 , pp. 1-16
    • Antonarakis, S.E.1
  • 6
    • 0036859562 scopus 로고    scopus 로고
    • Proteomic evaluation of intermediary metabolism enzyme proteins in fetal down syndrome cerebral cortex
    • Bajo M, Fruehauf J, Kim SH, Fountoulakis M, Lubec G. 2002. Proteomic evaluation of intermediary metabolism enzyme proteins in fetal Down syndrome cerebral cortex. Proteomics 2:1539-1546.
    • (2002) Proteomics , vol.2 , pp. 1539-1546
    • Bajo, M.1    Fruehauf, J.2    Kim, S.H.3    Fountoulakis, M.4    Lubec, G.5
  • 7
    • 0035226664 scopus 로고    scopus 로고
    • Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in down syndrome and Alzheimer's disease
    • Balcz B, Kirchner L, Cairns N, Fountoulakis M, Lubec G. 2001. Increased brain protein levels of carbonyl reductase and alcohol dehydrogenase in Down syndrome and Alzheimer's disease. J Neural Transm Suppl 61:193-202.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 193-202
    • Balcz, B.1    Kirchner, L.2    Cairns, N.3    Fountoulakis, M.4    Lubec, G.5
  • 11
    • 0033456265 scopus 로고    scopus 로고
    • Reliable automatic protein identification from matrix-assisted laser desorption/ ionization mass spectrometric peptide fingerprints
    • Berndt P, Hobohm U, Langen H. 1999. Reliable automatic protein identification from matrix-assisted laser desorption/ ionization mass spectrometric peptide fingerprints. Electrophoresis 20:3521-3526.
    • (1999) Electrophoresis , vol.20 , pp. 3521-3526
    • Berndt, P.1    Hobohm, U.2    Langen, H.3
  • 12
    • 0036918231 scopus 로고    scopus 로고
    • Manifold decreased protein levels of matrin 3, reduced motor protein HMP and hlark in fetal down syndrome brain
    • Bernert G, Fountoulakis M, Lubec G. 2002. Manifold decreased protein levels of matrin 3, reduced motor protein HMP and hlark in fetal Down syndrome brain. Proteomics 2:1752-1757.
    • (2002) Proteomics , vol.2 , pp. 1752-1757
    • Bernert, G.1    Fountoulakis, M.2    Lubec, G.3
  • 13
    • 0035090308 scopus 로고    scopus 로고
    • Cancer proteomics: From biomarker discovery to signal pathway profiling
    • Bichsel VE, Liotta LA, Petricoin EF III. 2001. Cancer proteomics: From biomarker discovery to signal pathway profiling. Cancer J 7:69-77.
    • (2001) Cancer J , vol.7 , pp. 69-77
    • Bichsel, V.E.1    Liotta, L.A.2    Petricoin III, E.F.3
  • 15
    • 0037434977 scopus 로고    scopus 로고
    • Biomedical informatics for proteomics
    • Boguski MS, McIntosh MW. 2003. Biomedical informatics for proteomics. Nature 422:233-237.
    • (2003) Nature , vol.422 , pp. 233-237
    • Boguski, M.S.1    McIntosh, M.W.2
  • 16
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.1
  • 18
    • 12244289683 scopus 로고    scopus 로고
    • Proteomic analysis of rat brain tissue: Comparison of protocols for two-dimensional gel electrophoresis analysis based on different solubilizing agents
    • Carboni L, Piubelli C, Righetti PG, Jansson B, Domenici E. 2002. Proteomic analysis of rat brain tissue: Comparison of protocols for two-dimensional gel electrophoresis analysis based on different solubilizing agents. Electrophoresis 23:4132-4141.
    • (2002) Electrophoresis , vol.23 , pp. 4132-4141
    • Carboni, L.1    Piubelli, C.2    Righetti, P.G.3    Jansson, B.4    Domenici, E.5
  • 19
    • 0034101261 scopus 로고    scopus 로고
    • Proteomics in medical microbiology
    • Cash P. 2000. Proteomics in medical microbiology. Electrophoresis 21:1187-1201.
    • (2000) Electrophoresis , vol.21 , pp. 1187-1201
    • Cash, P.1
  • 20
    • 0037101889 scopus 로고    scopus 로고
    • Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: Creatine kinase BB, glutamine synthase, and ubiquitin carboxyl-terminal hydrolase L-1
    • Castegna A, Aksenov M, Aksenova M, Thongboonkerd V, Klein JB, Pierce WM, Booze R, Markesbery WR, Butterfield DA. 2002a. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: Creatine kinase BB, glutamine synthase, and ubiquitin carboxyl-terminal hydrolase L-1. Free Radic Med 33:562-571.
    • (2002) Free Radic Med , vol.33 , pp. 562-571
    • Castegna, A.1    Aksenov, M.2    Aksenova, M.3    Thongboonkerd, V.4    Klein, J.B.5    Pierce, W.M.6    Booze, R.7    Markesbery, W.R.8    Butterfield, D.A.9
  • 21
    • 0036733145 scopus 로고    scopus 로고
    • Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: Dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71
    • Castegna A, Aksenov M, Thongboonkerd V, Klein JB, Pierce WM, Booze R, Markesbery WR, Butterfield DA. 2002b. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: Dihydropyrimidinase- related protein 2, alpha-enolase and heat shock cognate 71. J Neurochem 82:1524-1532.
    • (2002) J Neurochem , vol.82 , pp. 1524-1532
    • Castegna, A.1    Aksenov, M.2    Thongboonkerd, V.3    Klein, J.B.4    Pierce, W.M.5    Booze, R.6    Markesbery, W.R.7    Butterfield, D.A.8
  • 22
    • 0036744944 scopus 로고    scopus 로고
    • Comparative proteome analysis of human temporal cortex lobes by two-dimensional electrophoresis and identification of selected common proteins
    • Chen W, Ji J, Zhao R, Ru B. 2002. Comparative proteome analysis of human temporal cortex lobes by two-dimensional electrophoresis and identification of selected common proteins. Neurochem Res 27:871-881.
    • (2002) Neurochem Res , vol.27 , pp. 871-881
    • Chen, W.1    Ji, J.2    Zhao, R.3    Ru, B.4
  • 25
    • 0037354541 scopus 로고    scopus 로고
    • Protein levels of genes encoded on chromosome 21 in fetal down syndrome brain: Challenging the gene dosage effect hypothesis (Part I)
    • Cheon MS, Kim SH, Yaspo ML, Blasi F, Aoki Y, Melen K, Lubec G. 2003a. Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part I). Amino Acids 24:111-117.
    • (2003) Amino Acids , vol.24 , pp. 111-117
    • Cheon, M.S.1    Kim, S.H.2    Yaspo, M.L.3    Blasi, F.4    Aoki, Y.5    Melen, K.6    Lubec, G.7
  • 26
    • 0037355919 scopus 로고    scopus 로고
    • Protein levels of genes encoded on chromosome 21 in fetal down syndrome brain: Challenging the gene dosage effect hypothesis (Part II)
    • Cheon MS, Bajo M, Kim SH, Claudio JO, Stewart AK, Patterson D, Kruger WD, Kondoh H, Lubec G. 2003b. Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part II). Amino Acids 24:119-125.
    • (2003) Amino Acids , vol.24 , pp. 119-125
    • Cheon, M.S.1    Bajo, M.2    Kim, S.H.3    Claudio, J.O.4    Stewart, A.K.5    Patterson, D.6    Kruger, W.D.7    Kondoh, H.8    Lubec, G.9
  • 27
    • 0037356252 scopus 로고    scopus 로고
    • Protein levels of genes encoded on chromosome 21 in fetal down syndrome brain: Challenging the gene dosage effect hypothesis (Part III)
    • Cheon MS, Kim SH, Ovod V, Kopitar Jerala N, Morgan JI, Hatefi Y, Ijuin T, Takenawa T, Lubec G. 2003c. Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part III). Amino Acids 24:127-134.
    • (2003) Amino Acids , vol.24 , pp. 127-134
    • Cheon, M.S.1    Kim, S.H.2    Ovod, V.3    Kopitar Jerala, N.4    Morgan, J.I.5    Hatefi, Y.6    Ijuin, T.7    Takenawa, T.8    Lubec, G.9
  • 28
    • 0035321652 scopus 로고    scopus 로고
    • Comparative proteomics in bacterial pathogens
    • Cordwell SJ, Nouwens AS, Walsh BJ. 2001. Comparative proteomics in bacterial pathogens. Proteomics 1:461-472.
    • (2001) Proteomics , vol.1 , pp. 461-472
    • Cordwell, S.J.1    Nouwens, A.S.2    Walsh, B.J.3
  • 30
    • 0036016288 scopus 로고    scopus 로고
    • Detection of TOAD-64 in adult rat brain as revealed by two-dimensional protein gel electrophoresis followed by MALDI mass spectrometry possible modulatory effect of chronic haloperidol treatment
    • Dahmen N, Jungblut PR, Fischer V, Schrank M, Reuss S, Rujescu D, Hiemke C. 2002. Detection of TOAD-64 in adult rat brain as revealed by two-dimensional protein gel electrophoresis followed by MALDI mass spectrometry possible modulatory effect of chronic haloperidol treatment. Prog Neuropsychopharmacol Biol Psychiatry 26:693-698.
    • (2002) Prog Neuropsychopharmacol Biol Psychiatry , vol.26 , pp. 693-698
    • Dahmen, N.1    Jungblut, P.R.2    Fischer, V.3    Schrank, M.4    Reuss, S.5    Rujescu, D.6    Hiemke, C.7
  • 31
    • 0032585815 scopus 로고    scopus 로고
    • Molecular abnormalities of the brain in down syndrome: Relevance to Alzheimer's neurodegeneration
    • de la Monte SM. 1999. Molecular abnormalities of the brain in Down syndrome: Relevance to Alzheimer's neurodegeneration. J Neural Transm Suppl 57:1-19.
    • (1999) J Neural Transm Suppl , vol.57 , pp. 1-19
    • De la Monte, S.M.1
  • 32
    • 0038044258 scopus 로고    scopus 로고
    • Immuotherapy for Alzheimer's disease
    • Dodel RC, Hampel H, Du Y. 2003. Immuotherapy for Alzheimer's disease. Lancet Neurol 2:215-220.
    • (2003) Lancet Neurol , vol.2 , pp. 215-220
    • Dodel, R.C.1    Hampel, H.2    Du, Y.3
  • 33
    • 0035659240 scopus 로고    scopus 로고
    • Protein expression in down syndrome brain
    • Engidawork E, Lubec G. 2001. Protein expression in Down syndrome brain. Amino Acids 21:331-361.
    • (2001) Amino Acids , vol.21 , pp. 331-361
    • Engidawork, E.1    Lubec, G.2
  • 34
    • 0037339732 scopus 로고    scopus 로고
    • Molecular changes in fetal down syndrome brain
    • Engidawork E, Lubec G. 2003. Molecular changes in fetal Down syndrome brain. J Neurochem 84:895-904.
    • (2003) J Neurochem , vol.84 , pp. 895-904
    • Engidawork, E.1    Lubec, G.2
  • 35
    • 0035237465 scopus 로고    scopus 로고
    • Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal down syndrome
    • Engidawork E, Juranville J-F, Fountoulakis M, Dierssen M, Lubec G. 2001. Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome. J Neural Transm Suppl 61:117-130.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 117-130
    • Engidawork, E.1    Juranville, J.-F.2    Fountoulakis, M.3    Dierssen, M.4    Lubec, G.5
  • 36
    • 0037389843 scopus 로고    scopus 로고
    • Expression of hypothetical proteins in human fetal brain: Increased expression of hypothetical protein 28.5 kDa in down syndrome, a clue for its tentative role
    • Engidawork E, Gulesserian T, Fountoulakis M, Lubec G. 2003. Expression of hypothetical proteins in human fetal brain: Increased expression of hypothetical protein 28.5 kDa in Down syndrome, a clue for its tentative role. Mol Genet Metab 78:295-301.
    • (2003) Mol Genet Metab , vol.78 , pp. 295-301
    • Engidawork, E.1    Gulesserian, T.2    Fountoulakis, M.3    Lubec, G.4
  • 38
    • 0035663169 scopus 로고    scopus 로고
    • Proteomics: Current technologies and applications in neurological disorders and toxicology
    • Fountoulakis M. 2001. Proteomics: Current technologies and applications in neurological disorders and toxicology. Amino Acids 21:363-381.
    • (2001) Amino Acids , vol.21 , pp. 363-381
    • Fountoulakis, M.1
  • 39
    • 0032585827 scopus 로고    scopus 로고
    • Increased levels of 14-3-3 protein forms gamma and epsilon in the brain of patients with down syndrome and Alzheimer's disease
    • Fountoulakis M, Cairns N, Lubec G. 1999a. Increased levels of 14-3-3 protein forms gamma and epsilon in the brain of patients with Down syndrome and Alzheimer's disease. J Neural Transm Suppl 57:323-335.
    • (1999) J Neural Transm Suppl , vol.57 , pp. 323-335
    • Fountoulakis, M.1    Cairns, N.2    Lubec, G.3
  • 40
    • 0031445633 scopus 로고    scopus 로고
    • Large-scale identification of proteins of Haemophilus influenzae by amino acid composition analysis
    • Fountoulakis M, Juranville J-F, Berndt P. 1997a. Large-scale identification of proteins of Haemophilus influenzae by amino acid composition analysis. Electrophoresis 18:2968-2977.
    • (1997) Electrophoresis , vol.18 , pp. 2968-2977
    • Fountoulakis, M.1    Juranville, J.-F.2    Berndt, P.3
  • 41
    • 0344447096 scopus 로고    scopus 로고
    • Two-dimensional map of basic proteins of Haemophilus influenzae
    • Fountoulakis M, Takács B, Langen H. 1998b. Two-dimensional map of basic proteins of Haemophilus influenzae. Electrophoresis 19:761-766.
    • (1998) Electrophoresis , vol.19 , pp. 761-766
    • Fountoulakis, M.1    Takács, B.2    Langen, H.3
  • 42
    • 0345320443 scopus 로고    scopus 로고
    • Enrichment of low-abundance proteins of Haemophilus influenzae by hydrophobic interaction chromatography
    • Fountoulakis M, Takács M-F, Takács B. 1999b. Enrichment of low-abundance proteins of Haemophilus influenzae by hydrophobic interaction chromatography. J Chromatogr A 833:157-168.
    • (1999) J Chromatogr A , vol.833 , pp. 157-168
    • Fountoulakis, M.1    Takács, M.-F.2    Takács, B.3
  • 43
    • 0037354386 scopus 로고    scopus 로고
    • Proteomic analysis of the cell envelope fraction of Escherichia coli
    • Fountoulakis M, Gasser R. 2003. Proteomic analysis of the cell envelope fraction of Escherichia coli. Amino Acids 24:19-41.
    • (2003) Amino Acids , vol.24 , pp. 19-41
    • Fountoulakis, M.1    Gasser, R.2
  • 44
    • 0037442466 scopus 로고    scopus 로고
    • Enrichment of low-abundance brain proteins by preparative electrophoresis
    • Fountoulakis M, Juranville J-F. 2003. Enrichment of low-abundance brain proteins by preparative electrophoresis. Anal Biochem 313:267-282.
    • (2003) Anal Biochem , vol.313 , pp. 267-282
    • Fountoulakis, M.1    Juranville, J.-F.2
  • 45
    • 0031784879 scopus 로고    scopus 로고
    • Hydrolysis and amino acid composition analysis of proteins
    • Fountoulakis M, Lahm H-W. 1998. Hydrolysis and amino acid composition analysis of proteins. J Chromatogr A 826:109-134.
    • (1998) J Chromatogr A , vol.826 , pp. 109-134
    • Fountoulakis, M.1    Lahm, H.-W.2
  • 46
    • 0031214574 scopus 로고    scopus 로고
    • Identification of proteins by matrix-assisted laser desorption ionization-mass spectrometry following in-gel digestion in low-salt, nonvolatile buffer and simplified peptide recovery
    • Fountoulakis M, Langen H. 1997. Identification of proteins by matrix-assisted laser desorption ionization-mass spectrometry following in-gel digestion in low-salt, nonvolatile buffer and simplified peptide recovery. Anal Biochem 250:153-156.
    • (1997) Anal Biochem , vol.250 , pp. 153-156
    • Fountoulakis, M.1    Langen, H.2
  • 47
    • 0037269174 scopus 로고    scopus 로고
    • The mitochondrial proteins of the neuroblastoma cell line IMR 32
    • Fountoulakis M, Schlaeger J. 2003. The mitochondrial proteins of the neuroblastoma cell line IMR 32. Electrophoresis 24:260-275.
    • (2003) Electrophoresis , vol.24 , pp. 260-275
    • Fountoulakis, M.1    Schlaeger, J.2
  • 48
    • 0037176203 scopus 로고    scopus 로고
    • Proteomic analysis of the rat liver
    • Fountoulakis M, Suter L. 2002. Proteomic analysis of the rat liver. J Chromatogr B 782:197-218.
    • (2002) J Chromatogr B , vol.782 , pp. 197-218
    • Fountoulakis, M.1    Suter, L.2
  • 49
    • 0344015761 scopus 로고    scopus 로고
    • Design of protein purification pathways. Application to the proteome of Haemophilus influenzae using Heparin chromatography
    • Fountoulakis M, Takács B. 1998. Design of protein purification pathways. Application to the proteome of Haemophilus influenzae using Heparin chromatography. Protein Expression Purification 14:113-119.
    • (1998) Protein Expression Purification , vol.14 , pp. 113-119
    • Fountoulakis, M.1    Takács, B.2
  • 50
    • 70449658667 scopus 로고    scopus 로고
    • Effect of strong detergents and chaotropes on the protein detection in two-dimensional gels
    • Fountoulakis M, Takács B. 2001. Effect of strong detergents and chaotropes on the protein detection in two-dimensional gels. Electrophoresis 22:1593-1602.
    • (2001) Electrophoresis , vol.22 , pp. 1593-1602
    • Fountoulakis, M.1    Takács, B.2
  • 51
    • 0036435508 scopus 로고    scopus 로고
    • Enrichment and proteomic analysis of low-abundance bacterial proteins
    • Fountoulakis M, Takács B. 2002. Enrichment and proteomic analysis of low-abundance bacterial proteins. Methods Enzymol 358:288-306.
    • (2002) Methods Enzymol , vol.358 , pp. 288-306
    • Fountoulakis, M.1    Takács, B.2
  • 52
    • 0030805824 scopus 로고    scopus 로고
    • Two-dimensional map of haemophilus influenzae following protein enrichment by heparin chromatography
    • Fountoulakis M, Langen H, Evers S, Gray C, Takács B. 1997b. Two-dimensional map of Haemophilus influenzae following protein enrichment by heparin chromatography. Electrophoresis 18:1193-1202.
    • (1997) Electrophoresis , vol.18 , pp. 1193-1202
    • Fountoulakis, M.1    Langen, H.2    Evers, S.3    Gray, C.4    Takács, B.5
  • 54
    • 0033406428 scopus 로고    scopus 로고
    • Rat brain proteins: Two-dimensional protein database and variations in the expression level
    • Fountoulakis M, Schuller E, Hardmeier R, Berndt P, Lubec G. 1999c. Rat brain proteins: Two-dimensional protein database and variations in the expression level. Electrophoresis 20:3572-3579.
    • (1999) Electrophoresis , vol.20 , pp. 3572-3579
    • Fountoulakis, M.1    Schuller, E.2    Hardmeier, R.3    Berndt, P.4    Lubec, G.5
  • 55
    • 0033920278 scopus 로고    scopus 로고
    • Two-dimensional database of mouse liver proteins. Changes in hepatic protein levels following treatment with acetaminophen or its non-toxic regioisomer 3-acetamidophenol
    • Fountoulakis M, Berndt P, Boelsterli UA, Crameri F, Winter M, Albertini S, Suter L. 2000a. Two-dimensional database of mouse liver proteins. Changes in hepatic protein levels following treatment with acetaminophen or its non-toxic regioisomer 3-acetamidophenol. Electrophoresis 21:2148-2161.
    • (2000) Electrophoresis , vol.21 , pp. 2148-2161
    • Fountoulakis, M.1    Berndt, P.2    Boelsterli, U.A.3    Crameri, F.4    Winter, M.5    Albertini, S.6    Suter, L.7
  • 56
    • 0033997260 scopus 로고    scopus 로고
    • Differences in the protein level between neonatal and adult brain
    • Fountoulakis M, Hardmeier R, Schuller E, Lubec G. 2000b. Differences in the protein level between neonatal and adult brain. Electrophoresis 21:673-678.
    • (2000) Electrophoresis , vol.21 , pp. 673-678
    • Fountoulakis, M.1    Hardmeier, R.2    Schuller, E.3    Lubec, G.4
  • 62
    • 0035232099 scopus 로고    scopus 로고
    • Deterioration of the transcriptional, splicing and elongation machinery in the brain of fetal down syndrome
    • Freidl M, Gulesserian T, Lubec G, Fountoulakis M, Lubec B. 2001. Deterioration of the transcriptional, splicing and elongation machinery in the brain of fetal Down syndrome. J Neural Transm Suppl 61:47-58.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 47-58
    • Freidl, M.1    Gulesserian, T.2    Lubec, G.3    Fountoulakis, M.4    Lubec, B.5
  • 64
    • 0032935361 scopus 로고    scopus 로고
    • Analysis of the mouse proteome. (I) Brain proteins: Separation by two-dimensional electrophoresis and identification by mass spectrometry and genetic variation
    • Gauss C, Kalkum M, Lowe M, Lehrach H, Klose J. 1999. Analysis of the mouse proteome. (I) Brain proteins: Separation by two-dimensional electrophoresis and identification by mass spectrometry and genetic variation. Electrophoresis 20:575-600.
    • (1999) Electrophoresis , vol.20 , pp. 575-600
    • Gauss, C.1    Kalkum, M.2    Lowe, M.3    Lehrach, H.4    Klose, J.5
  • 66
    • 0010697803 scopus 로고    scopus 로고
    • Proteomics of multiprotein complexes: Answering fundamental questions in neuroscience
    • Grant SC, Husi H. 2001. Proteomics of multiprotein complexes: Answering fundamental questions in neuroscience. Trends Biotechnol 19:49-54.
    • (2001) Trends Biotechnol , vol.19 , pp. 49-54
    • Grant, S.C.1    Husi, H.2
  • 67
    • 0032947530 scopus 로고    scopus 로고
    • Decreased synaptosomal associated protein 25 levels in the brain of patients with down syndrome and Alzheimer's disease
    • Greber S, Lubec G, Cairns N, Fountoulakis M. 1999. Decreased synaptosomal associated protein 25 levels in the brain of patients with Down syndrome and Alzheimer's disease. Electrophoresis 20:928-934.
    • (1999) Electrophoresis , vol.20 , pp. 928-934
    • Greber, S.1    Lubec, G.2    Cairns, N.3    Fountoulakis, M.4
  • 68
    • 0035824631 scopus 로고    scopus 로고
    • Advances in proteome analysis by mass spectrometry
    • Griffin TJ, Aebersold R. 2001. Advances in proteome analysis by mass spectrometry. J Biol Chem 276:45497-45500.
    • (2001) J Biol Chem , vol.276 , pp. 45497-45500
    • Griffin, T.J.1    Aebersold, R.2
  • 69
    • 0035233607 scopus 로고    scopus 로고
    • Antioxidant proteins in fetal brain. Superoxide dismutase-1 (SOD-1) protein is not overexpressed in fetal down syndrome
    • Gulesserian T, Engidawork E, Fountoulakis M, Lubec G. 2001. Antioxidant proteins in fetal brain. Superoxide dismutase-1 (SOD-1) protein is not overexpressed in fetal Down syndrome. J Neural Transm Suppl 61:71-84.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 71-84
    • Gulesserian, T.1    Engidawork, E.2    Fountoulakis, M.3    Lubec, G.4
  • 70
    • 2542600839 scopus 로고    scopus 로고
    • Decreased brain levels of Lupus La protein and increased U5 small ribonucleoprotein-specific 40 kDa protein in fetal down syndrome
    • Gulesserian T, Engidawork E, Fountoulakis M, Lubec G. 2003. Decreased brain levels of Lupus La protein and increased U5 small ribonucleoprotein- specific 40 kDa protein in fetal Down syndrome. Cell Mol Biol 49:733-738.
    • (2003) Cell Mol Biol , vol.49 , pp. 733-738
    • Gulesserian, T.1    Engidawork, E.2    Fountoulakis, M.3    Lubec, G.4
  • 71
    • 0036391454 scopus 로고    scopus 로고
    • Proteome analysis of low-abundance proteins using multidimensional chromatography and isotope-coded affinity tags
    • Gygi SP, Rist B, Griffin TJ, Eng J, Aebersold R. 2002. Proteome analysis of low-abundance proteins using multidimensional chromatography and isotope-coded affinity tags. J Proteome Res 1:47-54.
    • (2002) J Proteome Res , vol.1 , pp. 47-54
    • Gygi, S.P.1    Rist, B.2    Griffin, T.J.3    Eng, J.4    Aebersold, R.5
  • 73
    • 0034177303 scopus 로고    scopus 로고
    • Actin and the agile spine: How and why do dendritic spines dance?
    • Halpain S. 2000. Actin and the agile spine: How and why do dendritic spines dance? Trends Neurosci 23:141-146.
    • (2000) Trends Neurosci , vol.23 , pp. 141-146
    • Halpain, S.1
  • 74
    • 0037434981 scopus 로고    scopus 로고
    • Disease proteomics
    • Hanash S. 2003. Disease proteomics. Nature 422:226-232.
    • (2003) Nature , vol.422 , pp. 226-232
    • Hanash, S.1
  • 75
    • 0030586426 scopus 로고    scopus 로고
    • 16-BAC/ SDS-PAGE: A two-dimensional gel electrophoresis system suitable for the separation of integral membrane proteins
    • Hartinger J, Stenius K, Hogemann D, Jahn R. 1996. 16-BAC/ SDS-PAGE: A two-dimensional gel electrophoresis system suitable for the separation of integral membrane proteins. Anal Biochem 240:126-133.
    • (1996) Anal Biochem , vol.240 , pp. 126-133
    • Hartinger, J.1    Stenius, K.2    Hogemann, D.3    Jahn, R.4
  • 76
    • 0027198862 scopus 로고
    • Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases
    • Henzel WJ, Billeci TM, Stults JT, Wong SC, Grimley C, Watanabe C. 1993. Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases. Proc Natl Acad Sci USA 90:5011-5015.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5011-5015
    • Henzel, W.J.1    Billeci, T.M.2    Stults, J.T.3    Wong, S.C.4    Grimley, C.5    Watanabe, C.6
  • 77
    • 0033672478 scopus 로고    scopus 로고
    • A turning point in proteome analysis: Sample prefractionation via multicompartment electrolyzers with isoelectric membranes
    • Herbert B, Righetti PG. 2000. A turning point in proteome analysis: Sample prefractionation via multicompartment electrolyzers with isoelectric membranes. Electrophoresis 21:3639-3648.
    • (2000) Electrophoresis , vol.21 , pp. 3639-3648
    • Herbert, B.1    Righetti, P.G.2
  • 78
  • 80
    • 0036548851 scopus 로고    scopus 로고
    • Alzheimer's disease: An overview of current and emerging therapeutic strategies
    • Jacobsen JS. 2002. Alzheimer's disease: An overview of current and emerging therapeutic strategies. Curr Top Med Chem 2:343-352.
    • (2002) Curr Top Med Chem , vol.2 , pp. 343-352
    • Jacobsen, J.S.1
  • 81
    • 0036403584 scopus 로고    scopus 로고
    • Application of laser capture microdissection to proteomics
    • Jain KK. 2002. Application of laser capture microdissection to proteomics. Methods Enzymol 356:157-167.
    • (2002) Methods Enzymol , vol.356 , pp. 157-167
    • Jain, K.K.1
  • 82
    • 0036310821 scopus 로고    scopus 로고
    • Conventional and functional proteomics using large format two-dimensional gel electrophoresis 24 hours after controlled cortical impact in postnatal day 17 rats
    • Jenkins LW, Peters GW, Dixon CE, Zhang X, Clark RS, Skinner JC, Marion DW, Adelson PD, Kochanek PM. 2002. Conventional and functional proteomics using large format two-dimensional gel electrophoresis 24 hours after controlled cortical impact in postnatal day 17 rats. J Neurotrauma 19:715-740.
    • (2002) J Neurotrauma , vol.19 , pp. 715-740
    • Jenkins, L.W.1    Peters, G.W.2    Dixon, C.E.3    Zhang, X.4    Clark, R.S.5    Skinner, J.C.6    Marion, D.W.7    Adelson, P.D.8    Kochanek, P.M.9
  • 86
    • 0032720603 scopus 로고    scopus 로고
    • Enrichment of human brain proteins by heparin chromatography
    • Karlsson K, Cairns N, Lubec G, Fountoulakis M. 1999. Enrichment of human brain proteins by heparin chromatography. Electrophoresis 20:2970-2976.
    • (1999) Electrophoresis , vol.20 , pp. 2970-2976
    • Karlsson, K.1    Cairns, N.2    Lubec, G.3    Fountoulakis, M.4
  • 87
    • 0036649486 scopus 로고    scopus 로고
    • The role of proteomics in toxicology: Identification of biomarkers of toxicity by protein expression analysis
    • Kennedy S. 2002. The role of proteomics in toxicology: Identification of biomarkers of toxicity by protein expression analysis. Biomarkers 7:269-290.
    • (2002) Biomarkers , vol.7 , pp. 269-290
    • Kennedy, S.1
  • 88
    • 0034796731 scopus 로고    scopus 로고
    • Proteome, transcriptome and genome: Top down or bottom up analysis?
    • Kettman JR, Frey JR, Lafkovits I. 2001. Proteome, transcriptome and genome: Top down or bottom up analysis? Biomol Eng 18:207-212.
    • (2001) Biomol Eng , vol.18 , pp. 207-212
    • Kettman, J.R.1    Frey, J.R.2    Lafkovits, I.3
  • 89
    • 0035794065 scopus 로고    scopus 로고
    • Decreased brain histamine-releasing factor protein in patients with down syndrome and Alzheimer's disease
    • Kim SH, Cairns N, Fountoulakis M, Lubec G. 2001a. Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease. Neurosci Lett 300:41-44.
    • (2001) Neurosci Lett , vol.300 , pp. 41-44
    • Kim, S.H.1    Cairns, N.2    Fountoulakis, M.3    Lubec, G.4
  • 90
    • 0035233637 scopus 로고    scopus 로고
    • Protein levels of human peroxiredoxin subtypes in brains of patients with alzheimer's disease and down syndrome
    • Kim SH, Cairns N, Fountoulakis M, Lubec G. 2001b. Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down syndrome. J Neural Transm Suppl 61:223-235
    • (2001) J Neural Transm Suppl , vol.61 , pp. 223-235
    • Kim, S.H.1    Cairns, N.2    Fountoulakis, M.3    Lubec, G.4
  • 91
    • 0035226665 scopus 로고    scopus 로고
    • Increased protein levels of heterogeneous nuclear ribonucleoprotein A2/B1 in fetal down syndrome brains
    • Kim SH, Dierssen M, Ferreres JC, Fountoulakis M, Lubec G. 2001c. Increased protein levels of heterogeneous nuclear ribonucleoprotein A2/B1 in fetal Down syndrome brains. J Neural Transm Suppl 61:273-280.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 273-280
    • Kim, S.H.1    Dierssen, M.2    Ferreres, J.C.3    Fountoulakis, M.4    Lubec, G.5
  • 92
    • 0035233817 scopus 로고    scopus 로고
    • Decreased protein levels of complex I 30-kDa subunit in fetal down syndrome brains
    • Kim SH, Fountoulakis M, Dierssen M, Lubec G. 2001d. Decreased protein levels of complex I 30-kDa subunit in fetal Down syndrome brains. J Neural Transm Suppl 61: 109-116.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 109-116
    • Kim, S.H.1    Fountoulakis, M.2    Dierssen, M.3    Lubec, G.4
  • 93
    • 0035805113 scopus 로고    scopus 로고
    • The reduction of NADH: Ubiquinone oxidoreductase 24 and 75-kDa subunits in the brain of patients with down syndrome and Alzheimer's disease
    • Kim SH, Vlkolinsky R, Cairns N, Fountoulakis M, Lubec G. 2001e. The reduction of NADH: Ubiquinone oxidoreductase 24 and 75-kDa subunits in the brain of patients with Down syndrome and Alzheimer's disease. Life Sci 68: 2741-2750.
    • (2001) Life Sci , vol.68 , pp. 2741-2750
    • Kim, S.H.1    Vlkolinsky, R.2    Cairns, N.3    Fountoulakis, M.4    Lubec, G.5
  • 94
    • 0036384213 scopus 로고    scopus 로고
    • Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and down syndrome
    • Kim SH, Fountoulakis M, Cairns N, Lubec G. 2002a. Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome. Biochem Biophys Res Comm 296:970-975.
    • (2002) Biochem Biophys Res Comm , vol.296 , pp. 970-975
    • Kim, S.H.1    Fountoulakis, M.2    Cairns, N.3    Lubec, G.4
  • 95
    • 0037155550 scopus 로고    scopus 로고
    • Human brain cytosolic histamine-N-methyltransferase is decreased in down syndrome and increased in Pick's disease
    • Kim SH, Krapfenbauer K, Cheon MS, Fountoulakis M, Cairns NJ, Lubec G. 2002b. Human brain cytosolic histamine-N-methyltransferase is decreased in Down syndrome and increased in Pick's disease. Neurosci Lett 321:169-172.
    • (2002) Neurosci Lett , vol.321 , pp. 169-172
    • Kim, S.H.1    Krapfenbauer, K.2    Cheon, M.S.3    Fountoulakis, M.4    Cairns, N.J.5    Lubec, G.6
  • 96
    • 0036808714 scopus 로고    scopus 로고
    • Reduced levels of DEAD-box proteins DBP-RB and p72 in fetal down syndrome brains
    • Kirchner SG, Kim SH, Fountoulakis M, Lubec G. 2002. Reduced levels of DEAD-box proteins DBP-RB and p72 in fetal Down syndrome brains. Neurochem Res 27:1141-1146.
    • (2002) Neurochem Res , vol.27 , pp. 1141-1146
    • Kirchner, S.G.1    Kim, S.H.2    Fountoulakis, M.3    Lubec, G.4
  • 97
    • 0016637146 scopus 로고
    • Protein mapping by combined isoelectric focusing and electrophoresis in mouse tissue. A novel approach to testing for induced point mutations in mammals
    • Klose J. 1975. Protein mapping by combined isoelectric focusing and electrophoresis in mouse tissue. A novel approach to testing for induced point mutations in mammals. Human-genetik 26:231-243.
    • (1975) Human-genetik , vol.26 , pp. 231-243
    • Klose, J.1
  • 99
    • 0037296959 scopus 로고    scopus 로고
    • Sodium dodecyl sulfate versus acid-labile surfactant gel electrophoresis: Comparative proteomic studies on rat retina and mouse brain
    • Konig S, Schmidt O, Rose K, Thanos S, Besselmann M, Zeller M. 2003. Sodium dodecyl sulfate versus acid-labile surfactant gel electrophoresis: Comparative proteomic studies on rat retina and mouse brain. Electrophoresis 24:751-756.
    • (2003) Electrophoresis , vol.24 , pp. 751-756
    • Konig, S.1    Schmidt, O.2    Rose, K.3    Thanos, S.4    Besselmann, M.5    Zeller, M.6
  • 101
    • 0346504199 scopus 로고    scopus 로고
    • A rat brain protein expression map including cytosolic and enriched mitochondrial and microsomal fractions
    • Krapfenbauer K, Fountoulakis M, Lubec G. 2003b. A rat brain protein expression map including cytosolic and enriched mitochondrial and microsomal fractions. Electrophoresis 24:1847-1870.
    • (2003) Electrophoresis , vol.24 , pp. 1847-1870
    • Krapfenbauer, K.1    Fountoulakis, M.2    Lubec, G.3
  • 102
    • 0034945320 scopus 로고    scopus 로고
    • Changes in the brain protein levels following administration of kainic acid
    • Krapfenbauer K, Berger M, Lubec G, Fountoulakis M. 2001a. Changes in the brain protein levels following administration of kainic acid. Electrophoresis 22:2086-2091.
    • (2001) Electrophoresis , vol.22 , pp. 2086-2091
    • Krapfenbauer, K.1    Berger, M.2    Lubec, G.3    Fountoulakis, M.4
  • 103
    • 0034826237 scopus 로고    scopus 로고
    • Kainic acid-induced changes in the level of low-abundance brain proteins
    • Krapfenbauer K, Berger M, Lubec G, Fountoulakis M. 2001b. Kainic acid-induced changes in the level of low-abundance brain proteins. Eur J Biochem 268:3532-3537.
    • (2001) Eur J Biochem , vol.268 , pp. 3532-3537
    • Krapfenbauer, K.1    Berger, M.2    Lubec, G.3    Fountoulakis, M.4
  • 104
    • 0036668064 scopus 로고    scopus 로고
    • Expression patterns of antioxidant proteins in the brain of patients with sporadic Creutzfeldt-Jacob disease
    • Krapfenbauer K, Yoo BC, Fountoulakis M, Mitrova E, Lubec G. 2002. Expression patterns of antioxidant proteins in the brain of patients with sporadic Creutzfeldt-Jacob disease. Electrophoresis 23:2541-2547.
    • (2002) Electrophoresis , vol.23 , pp. 2541-2547
    • Krapfenbauer, K.1    Yoo, B.C.2    Fountoulakis, M.3    Mitrova, E.4    Lubec, G.5
  • 105
    • 0344406145 scopus 로고    scopus 로고
    • Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders
    • Krapfenbauer K, Engidawork E, Cairns N, Fountoulakis M, Lubec G. 2003a. Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders. Brain Res 967: 152-160.
    • (2003) Brain Res , vol.967 , pp. 152-160
    • Krapfenbauer, K.1    Engidawork, E.2    Cairns, N.3    Fountoulakis, M.4    Lubec, G.5
  • 106
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • Kyte J, Doolittle RF. 1982. A simple method for displaying the hydropathic character of a protein. J Mol Biol 157:105-132.
    • (1982) J Mol Biol , vol.157 , pp. 105-132
    • Kyte, J.1    Doolittle, R.F.2
  • 107
    • 0033918391 scopus 로고    scopus 로고
    • Mass spectrometry: A tool for the identification of proteins separated by gels
    • Lahm HW, Langen H. 2000. Mass spectrometry: A tool for the identification of proteins separated by gels. Electrophoresis 21:2105-2114.
    • (2000) Electrophoresis , vol.21 , pp. 2105-2114
    • Lahm, H.W.1    Langen, H.2
  • 108
    • 0343852347 scopus 로고    scopus 로고
    • Effect of the protein application mode and the acrylamide concentration on the resolution of protein spots separated by two-dimensional gel electrophoresis
    • Langen H, Röder D, Juranville J-F, Fountoulakis M. 1997. Effect of the protein application mode and the acrylamide concentration on the resolution of protein spots separated by two-dimensional gel electrophoresis. Electrophoresis 18: 2085-2090.
    • (1997) Electrophoresis , vol.18 , pp. 2085-2090
    • Langen, H.1    Röder, D.2    Juranville, J.-F.3    Fountoulakis, M.4
  • 113
    • 0033613767 scopus 로고    scopus 로고
    • Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with down syndrome
    • Lubec G, Labudova O, Cairns N, Fountoulakis M. 1999b. Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with Down syndrome. Neuroscience Lett 260:141-145.
    • (1999) Neuroscience Lett , vol.260 , pp. 141-145
    • Lubec, G.1    Labudova, O.2    Cairns, N.3    Fountoulakis, M.4
  • 114
    • 0032585823 scopus 로고    scopus 로고
    • Expression of the dihydropyrimidinase related protein 2 (DRP-2) in down syndrome and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at the protein level
    • Lubec G, Nonaka M, Krapfenbauer K, Gratzer M, Cairns N, Fountoulakis M. 1999e. Expression of the dihydropyrimidinase related protein 2 (DRP-2) in Down syndrome and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at the protein level. J Neural Transm Suppl 57:161-177.
    • (1999) J Neural Transm Suppl , vol.57 , pp. 161-177
    • Lubec, G.1    Nonaka, M.2    Krapfenbauer, K.3    Gratzer, M.4    Cairns, N.5    Fountoulakis, M.6
  • 115
    • 0028575316 scopus 로고
    • Error-tolerant identification of peptides in sequence databases by peptide sequence tags
    • Mann M, Wilm M. 1994. Error-tolerant identification of peptides in sequence databases by peptide sequence tags. Anal Chem 66:4390-4399.
    • (1994) Anal Chem , vol.66 , pp. 4390-4399
    • Mann, M.1    Wilm, M.2
  • 117
    • 0016711037 scopus 로고
    • High resolution two-dimensional electrophoresis of proteins
    • O'Farrell PH. 1975. High resolution two-dimensional electrophoresis of proteins. J Biol Chem 250:4007-4021.
    • (1975) J Biol Chem , vol.250 , pp. 4007-4021
    • O'Farrell, P.H.1
  • 120
    • 0034775513 scopus 로고    scopus 로고
    • From cDNA microarrays to high-throughput proteomics. Implications in the search for preventive initiatives to slow the clinical progression of Alzheimer's disease dementia
    • Pasinetti GM, Ho L. 2001. From cDNA microarrays to high-throughput proteomics. Implications in the search for preventive initiatives to slow the clinical progression of Alzheimer's disease dementia. Restor Neurol Neurosci 18:137-142.
    • (2001) Restor Neurol Neurosci , vol.18 , pp. 137-142
    • Pasinetti, G.M.1    Ho, L.2
  • 122
    • 0023989064 scopus 로고
    • Improved tools for biological sequence comparison
    • Pearson WR, Lipman DJ. 1988. Improved tools for biological sequence comparison. Proc Natl Acad Sci USA 85:2444-2448.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2444-2448
    • Pearson, W.R.1    Lipman, D.J.2
  • 124
    • 0035356236 scopus 로고    scopus 로고
    • Prefractionation techniques in proteome analysis
    • Righetti PG, Castagna A, Herbert B. 2001. Prefractionation techniques in proteome analysis. Anal Chem 73:320A-326A.
    • (2001) Anal Chem , vol.73
    • Righetti, P.G.1    Castagna, A.2    Herbert, B.3
  • 126
    • 0034093383 scopus 로고    scopus 로고
    • Proteomics in molecular medicine: Applications in central nervous systems disorders
    • Rohlff C. 2000. Proteomics in molecular medicine: Applications in central nervous systems disorders. Electrophoresis 21: 1227-1234.
    • (2000) Electrophoresis , vol.21 , pp. 1227-1234
    • Rohlff, C.1
  • 127
    • 0036624336 scopus 로고    scopus 로고
    • Proteomic approaches to central nervous system disorders
    • Rohlff C, Southan C. 2002. Proteomic approaches to central nervous system disorders. Curr Opin Mol Ther 4:251-258.
    • (2002) Curr Opin Mol Ther , vol.4 , pp. 251-258
    • Rohlff, C.1    Southan, C.2
  • 128
    • 0034066471 scopus 로고    scopus 로고
    • Membrane proteins and proteomics: Un amour impossible?
    • Santoni V, Molloy M, Rabilloud T. 2000. Membrane proteins and proteomics: Un amour impossible? Electrophoresis 21:1054-1070.
    • (2000) Electrophoresis , vol.21 , pp. 1054-1070
    • Santoni, V.1    Molloy, M.2    Rabilloud, T.3
  • 129
    • 0023472472 scopus 로고
    • Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
    • Schägger H, von Jagow G. 1987. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 166:368-379.
    • (1987) Anal Biochem , vol.166 , pp. 368-379
    • Schägger, H.1    Von Jagow, G.2
  • 130
    • 0032585812 scopus 로고    scopus 로고
    • The down syndrome critical region
    • Shapiro BL. 1999. The Down syndrome critical region. J Neural Transm Suppl 57:41-60.
    • (1999) J Neural Transm Suppl , vol.57 , pp. 41-60
    • Shapiro, B.L.1
  • 131
    • 0002640896 scopus 로고    scopus 로고
    • Cancer proteomics: From signaling networks to tumor markers
    • Simpson RJ, Dorow DS. 2001. Cancer proteomics: From signaling networks to tumor markers. Trends Biotechnol 19:S40-S48.
    • (2001) Trends Biotechnol , vol.19
    • Simpson, R.J.1    Dorow, D.S.2
  • 132
    • 0036668519 scopus 로고    scopus 로고
    • Alterations of stress related proteins in genetically altered mice revealed by two-dimensional differential in-gel electrophoresis analysis
    • Skynner HA, Rosahl TW, Knowles MR, Salim K, Reid L, Cothliff R, McAllister G, Guest PC. 2002. Alterations of stress related proteins in genetically altered mice revealed by two-dimensional differential in-gel electrophoresis analysis. Proteomics 2:1018-1025.
    • (2002) Proteomics , vol.2 , pp. 1018-1025
    • Skynner, H.A.1    Rosahl, T.W.2    Knowles, M.R.3    Salim, K.4    Reid, L.5    Cothliff, R.6    McAllister, G.7    Guest, P.C.8
  • 133
    • 0033919787 scopus 로고    scopus 로고
    • Proteomics: Applications and opportunities in preclinical drug development
    • Steiner S, Witzmann FA. 2000. Proteomics: Applications and opportunities in preclinical drug development. Electrophoresis 21:2099-2104.
    • (2000) Electrophoresis , vol.21 , pp. 2099-2104
    • Steiner, S.1    Witzmann, F.A.2
  • 134
    • 0011644705 scopus 로고    scopus 로고
    • Protein purification: Theoretical and methodological considerations
    • Meyers RA, editor. Chichester: John Wiley & Sons Ltd.
    • Takács BJ. 2001. Protein purification: Theoretical and methodological considerations. In: Meyers RA, editor. Encyclopedia of analytical chemistry. Chichester: John Wiley & Sons Ltd. pp 5955-5970.
    • (2001) Encyclopedia of Analytical Chemistry , pp. 5955-5970
    • Takács, B.J.1
  • 136
    • 0037434980 scopus 로고    scopus 로고
    • From genomics to proteomics
    • Tyers M, Mann M. 2003. From genomics to proteomics. Nature 422:193-197.
    • (2003) Nature , vol.422 , pp. 193-197
    • Tyers, M.1    Mann, M.2
  • 137
    • 0034969003 scopus 로고    scopus 로고
    • Decreased brain levels of 2′,3′-cyclic nucleotide-3′- phosphodiesterase in down syndrome and Alzheimer's disease
    • Vlkolinsky R, Cairns N, Fountoulakis M, Lubec G. 2001. Decreased brain levels of 2′,3′-cyclic nucleotide-3′-phosphodiesterase in Down syndrome and Alzheimer's disease. Neurobiol Aging 22:547-553.
    • (2001) Neurobiol Aging , vol.22 , pp. 547-553
    • Vlkolinsky, R.1    Cairns, N.2    Fountoulakis, M.3    Lubec, G.4
  • 139
    • 0032489017 scopus 로고    scopus 로고
    • Effect of the hydrolysis method on the determination of amino acid composition of proteins
    • Weiss M, Manneberg M, Juranville J-F, Lahm H-W, Fountoulakis M. 1998. Effect of the hydrolysis method on the determination of amino acid composition of proteins. J Chromatogr 795:263-275.
    • (1998) J Chromatogr , vol.795 , pp. 263-275
    • Weiss, M.1    Manneberg, M.2    Juranville, J.-F.3    Lahm, H.-W.4    Fountoulakis, M.5
  • 140
    • 0036288814 scopus 로고    scopus 로고
    • Reduction of actin related protein complex 2/3 in fetal down syndrome brain
    • Weitzdoerfer R, Fountoulakis M, Lubec G. 2002. Reduction of actin related protein complex 2/3 in fetal Down syndrome brain. Biochem Biophys Res Commun 293:836-841.
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 836-841
    • Weitzdoerfer, R.1    Fountoulakis, M.2    Lubec, G.3
  • 141
    • 0035226716 scopus 로고    scopus 로고
    • Fetal life in down syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure
    • Weitzdoerfer R, Dierssen M, Fountoulakis M, Lubec G. 2001a. Fetal life in Down syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure. J Neural Transm Suppl 61:59-70.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 59-70
    • Weitzdoerfer, R.1    Dierssen, M.2    Fountoulakis, M.3    Lubec, G.4
  • 142
    • 0035232934 scopus 로고    scopus 로고
    • Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal down syndrome brain
    • Weitzdoerfer R, Stolzlechner D, Dierssen M, Ferreres J, Fountoulakis M, Lubec G. 2001b. Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal Down syndrome brain. J Neural Transm Suppl 61:347-359.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 347-359
    • Weitzdoerfer, R.1    Stolzlechner, D.2    Dierssen, M.3    Ferreres, J.4    Fountoulakis, M.5    Lubec, G.6
  • 144
    • 0035103479 scopus 로고    scopus 로고
    • Synaptsomal-proteins beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma (gamma-SNAP) and synaptotagmin I in the brain of patients with down syndrome and Alzheimer's disease
    • Yoo BC, Cairns N, Fountoulakis M, Lubec G. 2001a. Synaptsomal-proteins beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma (gamma-SNAP) and synaptotagmin I in the brain of patients with Down syndrome and Alzheimer's disease. Dement Geriatr Cogn Disord 12:219-225.
    • (2001) Dement Geriatr Cogn Disord , vol.12 , pp. 219-225
    • Yoo, B.C.1    Cairns, N.2    Fountoulakis, M.3    Lubec, G.4
  • 145
    • 0035170823 scopus 로고    scopus 로고
    • Changes of voltage-dependent anion channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and down syndrome
    • Yoo BC, Fountoulakis M, Cairns N, Lubec G. 2001b. Changes of voltage-dependent anion channel proteins VDAC1 and VDAC2 brain levels in patients with Alzheimer's disease and Down syndrome. Electrophoresis 22:172-179.
    • (2001) Electrophoresis , vol.22 , pp. 172-179
    • Yoo, B.C.1    Fountoulakis, M.2    Cairns, N.3    Lubec, G.4
  • 146
    • 0035233820 scopus 로고    scopus 로고
    • Expression patterns of chaperone proteins in cerebral cortex of the fetus with down syndrome. Dysregulation of the T-complex protein 1
    • Yoo BC, Fountoulakis M, Dierssen M, Lubec G. 2001c. Expression patterns of chaperone proteins in cerebral cortex of the fetus with Down syndrome. Dysregulation of the T-complex protein 1. J Neural Transm Suppl 61:321-334.
    • (2001) J Neural Transm Suppl , vol.61 , pp. 321-334
    • Yoo, B.C.1    Fountoulakis, M.2    Dierssen, M.3    Lubec, G.4
  • 147
    • 0034805931 scopus 로고    scopus 로고
    • Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease
    • Yoo BC, Kim SH, Cairns N, Fountoulakis M, Lubec G. 2001d. Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease. Biochem Biophys Res Commun 280:249-258.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 249-258
    • Yoo, B.C.1    Kim, S.H.2    Cairns, N.3    Fountoulakis, M.4    Lubec, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.