Physico-chemical characterization and synthesis of neuronally active α-conotoxins

European Journal of Biochemistry

Volumn 271, Issue 12, 2004, Pages 2294-2304

  Loughnan, Marion L ^a   Alewood, Paul F ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

conotoxins; Conus; Peptide synthesis; Post translational modifications; Sulfotyrosine

Indexed keywords

ALPHA CONOTOXIN; ALPHA CONOTOXIN AUIB; ALPHA CONOTOXIN IMI; ALPHA CONOTOXIN IMII; ALPHA CONOTOXIN IMIIA; ARGINYLASPARTYLORNITHYLCYSTEINYLCYSTEINYLTYROSYLPROLYLTYROSYLCYSTEINYLASPAR AGINYLMETHIONYLSERYLASPARAGINYLPROLYLGLUTAMINYLISOLEUCYLCYSTEINE; ARGINYLASPARTYLPROLYLCYSTEINYLCYSTEINYLSERYLASPARAGINYLPROLYLVALYLCYSTEINYL THREONYLVALYLHISTIDYLASPARAGINYLPROLYLGLUTAMINYLISOLEUCYLCYSTEINE; CYSTEINYLCYSTEINYLSERYLHISTIDYLPROLYLALANYLCYSTEINYLALANYLALANYLASPARAGINYL ASPARAGINYLGLUTAMINYLASPARTYLTYROSYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLASPARAGINYLVALYLCYSTEINYLHISTIDYLLEUCYLGLUTAMY LHISTIDYLSERYLASPARAGINYLLEUCYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLASPARTYLPROLYLARGINYLCYSTEINYLASPARAGINYLMETHI ONYLASPARAGINYLASPARAGINYLPROLYLASPARTYLTYROSYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLASPARTYLPROLYLARGINYLCYSTEINYLASPARAGINYLTYROS YLASPARTYLHISTIDYLPROLYLGLUTAMYLISOLEUCYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLHISTIDYLPROLYLALANYLCYSTEINYLALANYLGLYCYLASPAR AGINYLASPARAGINYLGLUTAMINYLHISTIDYLISOLEUCYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLLEUCYLPROLYLPROLYLCYSTEINYLALANYLALANYLASPARAG INYLASPARAGINYLPROLYLASPARTYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLLEUCYLPROLYLPROLYLCYSTEINYLALANYLLEUCYLASPARAG INYLASPARAGINYLPROLYLASPARTYLTYROSYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLLEUCYLPROLYLPROLYLCYSTEINYLALANYLLEUCYLSERYLAS PARAGINYLPROLYLASPARTYLTYROSYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLTYROSYLPROLYLPROLYLCYSTEINYLPHENYLALANYLALANYL THREONYLASPARAGINYLSERYLASPARTYLTYROSYLCYSTEINE; GLYCYLCYSTEINYLCYSTEINYLSERYLTYROSYLPROLYLPROLYLCYSTEINYLPHENYLALANYLTHREON YLASPARAGINYLSERYLGLYCYLTYROSYLCYSTEINE; GLYCYLGLYCYLCYSTEINYLCYSTEINYLSERYLHISTIDYLPROLYLALANYLCYSTEINYLALANYLALANY LASPARAGINYLASPARAGINYLGLUTAMINYLASPARTYLTYROSYLCYSTEINE; GLYCYLGLYCYLCYSTEINYLCYSTEINYLSERYLHISTIDYLPROLYLALANYLCYSTEINYLPHENYLALANY LALANYLSERYLASPARAGINYLPROLYLASPARTYLTYROSYLCYSTEINE; ISOLEUCYLARGINYLASPARTYL GAMMA CYSTEINYLCYSTEINYLSERYLASPARAGINYLPROLYLALANYLCYSTEINYLARGINYLVALYLASPARAGINYLAS PARAGINYLORNITHYLHISTIDYLVALYLCYSTEINE; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; SNAIL VENOM; UNCLASSIFIED DRUG;

CHROMATOGRAPHY; DISULFIDE BOND; GASTROPOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR BIOLOGY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN ISOLATION; PROTEIN SYNTHESIS; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; SHORT SURVEY; SNAIL; TOXIN ANALYSIS; TOXIN STRUCTURE; TOXIN SYNTHESIS;

ANIMALS; CONOTOXINS; DISULFIDES; MULTIGENE FAMILY; NEURONS; PEPTIDE BIOSYNTHESIS; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, NICOTINIC;

GASTROPODA;

EID: 3042513389     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04146.x     Document Type: Short Survey

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