Oxidative DNA damage and activation of c-Jun N-terminal kinase pathway in fibroblasts from patients with hereditary spastic paraplegia

Cellular and Molecular Neurobiology

Volumn 25, Issue 8, 2005, Pages 1245-1254

  Milano, Andreina ^a   Gesualdi, Nicola Montesano ^a   Teperino, Raffaele ^a   Esposito, Franca ^a   Cocozza, Sergio ^a   Ungaro, Paola ^b,c  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CNR   (Italy)

^c Istituto di Endocrinologia ed Oncologia Sperimentale G Salvatore   (Italy)

Author keywords

Comet assay; DNA damage; JNK phosphorylation; Reactive oxygen species; Western blotting

Indexed keywords

DNA; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; COMET ASSAY; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVATION; FIBROBLAST; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUMAN CELL; NEUROPATHOLOGY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

BLOOD PROTEINS; CELLS, CULTURED; CULTURE MEDIA; DNA DAMAGE; ENZYME ACTIVATION; FIBROBLASTS; HUMANS; HYDROGEN PEROXIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; OXIDATIVE STRESS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SPASTIC PARAPLEGIA, HEREDITARY;

EID: 29844455894     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-005-8501-2     Document Type: Article

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