Targeting plasma cells in autoimmune diseases

Journal of Experimental Medicine

Volumn 199, Issue 11, 2004, Pages 1451-1454

  Tarlinton, David M ^a   Hodgkin, Philip D ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIGEN; AUTOANTIBODY;

AUTOIMMUNE DISEASE; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; HUMAN; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; PLASMA CELL; PRIORITY JOURNAL; REVIEW; STEM CELL;

ANTIGENS, CD45; AUTOIMMUNE DISEASES; HUMANS; MEMBRANE GLYCOPROTEINS; PLASMA CELLS; PROTEOGLYCANS; STEM CELLS; SYNDECANS;

EID: 2942692040     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040719     Document Type: Review

References (39)

1. Drenkard, C., A.R. Villa, C. Garcia-Padilla, M.E. Perez-Vazquez, and D. Alarcon-Segovia. 1996. Remission of systematic lupus erythematosus. Medicine (Baltimore). 75:88-98.
2. Looney, R.J., J. Anolik, and I. Sanz. 2004. B cells as therapeutic targets for rheumatic diseases. Curr. Opin. Rheumatol. 16:180-185.
3. Zinkernagel, R.M. 1996. Immunology taught by viruses. Science. 271:173-178.
4. Manz, R.A., A. Thiel, and A. Radbruch. 1997. Lifetime of plasma cells in the bone marrow. Nature. 388:133-134.
5. Slifka, M.K., R. Antia, J.K. Whitmire, and R. Ahmed. 1998. Humoral immunity due to long-lived plasma cells. Immunity. 8:363-372.
6. Hoyer, B.F., K. Moser, A.E. Hauser, A. Peddinghaus, C. Voigt, D. Eilat, A. Radbruch, F. Hiepe, and R.A. Manz. 2004. Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice. J. Exp. Med. 199:1577-1584.
7. Fagraeus, A. 1948. The plasma cellular reaction and its relation to the formation of antibodies in vitro. J. Immunol. 58:1-13.
8. Ho, F., J.E. Lortan, I.C. MacLennan, and M. Khan. 1986. Distinct short-lived and long-lived antibody-producing cell populations. Eur. J. Immunol. 16:1297-1301.
9. Van Rooijen, N., E. Claassen, and P. Eikelenboom. 1986. Is there a single differentiation pathway for all antibody-forming cells in the spleen? Immunol. Today. 7:193-195.
10. Smith, K.G., T.D. Hewitson, G.J. Nossal, and D.M. Tarlinton. 1996. The phenotype and fate of the antibody-forming cells of the splenic foci. Eur. J. Immunol. 26:444-448.
11. MacLennan, I.C., K.M. Toellner, A.F. Cunningham, K. Serre, D.M. Sze, E. Zuniga, M.C. Cook, and C.G. Vinuesa. 2003. Extrafollicular antibody responses. Immunol. Rev. 194:8-18.
12. Benner, R., W. Hijmans, and JJ. Haaijman. 1981. The bone marrow: the major source of serum immunoglobulins, but still a neglected site of antibody formation. Clin. Exp. Immunol. 46:1-8.
13. Smith, K.G., A. Light, G.J. Nossal, and D.M. Tarlinton. 1997. The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response. EMBO J. 16:2996-3006.
14. Manz, R.A., M. Lohning, G. Cassese, A. Thiel, and A. Radbruch. 1998. Survival of long-lived plasma cells is independent of antigen. Int. Immunol. 10:1703-1711.
15. Hasbold, J., L.M. Corcoran, D.M. Tarlinton, S.G. Tangye, and P.D. Hodgkin. 2004. Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation. Nat. Immunol. 5:55-63.
16. Sanderson, R.D., P. Lalor, and M. Bernfield. 1989. B lymphocytes express and lose syndecan at specific stages of differentiation. Cell Regul. 1:27-35.
17. Underhill, G.H., K.P. Kolli, and G.S. Kansas. 2003. Complexity within the plasma cell compartment of mice deficient in both E- and P-selectin: implications for plasma cell differentiation. Blood. 102:4076-4083.
18. Ellyard, J.I., D.T. Avery, T.G. Phan, N.J. Hare, P.D. Hodgkin, and S.G. Tangye. 2003. Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow. Blood. 103):3805-3812.
19. Terstappen, L.W., S. Johnsen, I.M. Segers-Nolten, and M.R. Loken. 1990. Identification and characterization of plasma cells in normal human bone marrow by high-resolution flow cytometry. Blood. 76:1739-1747.
20. de Boer, B.A., I. Voigt, H.J. Kim, S.A. Camacho, M. Lipp, R. Forster, and C. Berek. 2000. Affinity maturation in ectopic germinal centers. Curr. Top. Microbiol. Immunol. 251:191-195.
21. Cassese, G., S. Lindenau, B. de Boer, S. Arce, A. Hauser, G. Riemekasten, C. Berek, F. Hiepe, V. Krenn, A. Radbruch, and R.A. Manz. 2001. Inflamed kidneys of NZB/W mice are a major site for the homeostasis of plasma cells. Eur. J. Immunol. 31:2726-2732.
22. Takahashi, Y., P.R. Dutta, D.M. Cerasoli, and G. Kelsoe. 1998. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection. J. Exp. Med. 187:885-895.
23. William, J., C. Euler, S. Christensen, and M.J. Shlomchik. 2002. Evolution of autoantibody responses via somatic hypermutation outside of germinal centers. Science. 297:2066-2070.
24. Tarlinton, D.M., and K.G. Smith. 2000. Dissecting affinity maturation: a model explaining selection of antibody-forming cells and memory B cells in the germinal centre. Immunol. Today. 21:436-441.
25. Cassese, G., S. Arce, A.E. Hauser, K. Lehnert, B. Moewes, M. Mostarac, G. Muehlinghaus, M. Szyska, A. Radbruch, and R.A. Manz. 2003. Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals. J. Immunol. 171:1684-1690.
26. Hargreaves, D.C., P.L. Hyman, T.T. Lu, V.N. Ngo, A. Bidgol, G. Suzuki, Y.R. Zou, D.R. Littman, and J.G. Cyster. 2001. A coordinated change in chemokine responsiveness guides plasma cell movements. J. Exp. Med. 194:45-56.
27. Tew, J.G., G.F. Burton, A.K. Szakal, and M.H. Kosco. 1988. A subpopulation of germinal center B cells differentiate directly into antibody forming cells upon secondary immunization. Adv. Exp. Med. Biol. 237:215-220.
28. Tangye, S.G., D.T. Avery, and P.D. Hodgkin. 2003. A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells. J. Immunol. 170:261-269.
29. O'Connor, B.P., M. Cascalho, and R.J. Noelle. 2002. Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population. J. Exp. Med. 195:737-745.
30. McHeyzer-Williams, L.J., M. Cool, and M.G. McHeyzer-Williams. 2000. Antigen-specific B cell memory. Expression and replenishment of a novel B220(-) memory B cell compartment. J. Exp. Med. 191:1149-1166.
31. Shapiro-Shelef, M., K.I. Lin, L.J. McHeyzer-Williams, J. Liao, M.G. McHeyzer-Williams, and K. Calame. 2003. Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. Immunity. 19:607-620.
32. Arce, E., D.G. Jackson, M.A. Gill, L.B. Bennett, J. Banchereau, and V. Pascual. 2001. Increased frequency of pregerminal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus. J. Immunol. 167:2361-2369.
33. Medina, F., C. Segundo, A. Campos-Caro, I. Gonzalez-Garcia, and J.A. Brieva. 2002. The heterogeneity shown by human plasma cells from tonsil, blood, and bone marrow reveals graded stages of increasing maturity, but local profiles of adhesion molecule expression. Blood. 99:2154-2161.
34. Arce, S., E. Luger, G. Muehlinghaus, G. Cassese, A. Hauser, A. Horst, K. Lehnert, M. Odendahl, D. Honemann, K.D. Heller, H. Kleinschmidt, C. Berek, T. Dorner, V. Krenn, F. Hiepe, R. Bargou, A. Radbruch, and R.A. Manz. 2004. CD38 low IgG-secreting cells are precursors of various CD38 high-expressing plasma cell populations. J. Leukoc. Biol. 10.1189/jlb.0603279.
35. Jacobi, A.M., M. Odendahl, K. Reiter, A. Bruns, G.R. Burmester, A. Radbruch, G. Valet, P.E. Lipsky, and T. Dorner. 2003. Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus. Arthritis Rheum. 48:1332-1342.
36. Daikh, D.I., B.K. Finck, P.S. Linsley, D. Hollenbaugh, and D. Wofsy. 1997. Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways. J. Immunol. 159:3104-3108.
37. Avery, D.T., S.L. Kalled, J.I. Ellyard, C. Ambrose, S.A. Bixler, M. Thien, R. Brink, F. Mackay, P.D. Hodgkin, and S.G. Tangye. 2003. BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J. Clin. Invest. 112:286-297.
38. Balabanian, K., J. Couderc, L. Bouchet-Delbos, A. Amara, D. Berrebi, A. Foussat, F. Baleux, A. Portier, I. Durand-Gasselin, R.L. Coffman, et al. 2003. Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus. J. Immunol. 170:3392-3400.
39. Minges Wols, H.A., G.H. Underhill, G.S. Kansas, and P.L. Witte. 2002. The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity. J. Immunol. 169:4213-4221.