Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals

Journal of Immunology

Volumn 171, Issue 4, 2003, Pages 1684-1690

  Cassese, Giuliana ^a   Arce, Sergio ^a   Hauser, Anja E ^a   Lehnert, Katja ^a   Moewes, Beate ^a   Mostarac, Miro ^a   Muehlinghaus, Gwendolin ^a   Szyska, Martin ^a   Radbruch, Andreas ^a   Manz, Rudolf A ^a  

^a DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HERMES ANTIGEN; INTERLEUKIN 5; INTERLEUKIN 6; STROMAL CELL DERIVED FACTOR 1ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CELL ADHESION; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0042591464     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.4.1684     Document Type: Article

References (47)

1. Jerne, N. K., C. Henry, A. A. Nordin, H. Fuji, A. M. Koros, and I. Lefkovits. 1974. Plaque forming cells: methodology and theory. Transplant Rev. 18:130.
2. Slifka, M. K., and R. Ahmed. 1996. Long-term humoral immunity against viruses: revisiting the issue of plasma cell longevity. Trends Microbiol. 4:394.
3. Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54.
4. Ho, F., J. E. Lortan, I. C. MacLennan, and M. Khan. 1986. Distinct short-lived and long-lived antibody-producing cell populations. Eur. J. Immunol. 16:1297.
5. Slifka, M. K., and R. Ahmed. 1998. Long-lived plasma cells: a mechanism for maintaining persistent antibody production. Curr. Opin. Immunol. 10:252.
6. McHeyzer-Williams, M. G., and R. Ahmed. 1999. B cell memory and the long-lived plasma cell. Curr. Opin. Immunol. 11:172.
7. Slifka, M. K., R. Antia, J. K. Whitmire, and R. Ahmed. 1998. Humoral immunity due to long-lived plasma cells. Immunity 8:363.
8. Manz, R. A., M. Lohning, G. Cassese, A. Thiel, and A. Radbruch. 1998. Survival of long-lived plasma cells is independent of antigen. Int. Immunol. 10:1703.
9. Sze, D. M., K. M. Toellner, C. Garcia de Vinuesa, D. R. Taylor, and I. C. MacLennan. 2000. Intrinsic constraint on plasmablast growth and extrinsic limits of plasma cell survival. J. Exp. Med. 192:813.
10. Manz, R. A., and A. Radbruch. 2002. Plasma cells for a lifetime? Eur. J. Immunol. 32:923.
11. Manz, R. A., S. Arce, G. Cassese, A. E. Hauser, F. Hiepe, and A. Radbruch. 2002. Humoral immunity and long-lived plasma cells. Curr. Opin. Immunol. 14:517.
12. Osmond, D. G. 1990. B cell development in the bone marrow. Semin. Immunol. 2:173.
13. Rolink, A., and F. Melchers. 1993. B lymphopoiesis in the mouse. Adv. Immunol. 53:123.
14. Freitas, A., and J. Chen. 2002. Introduction: regulation of lymphocyte homeostasis. Microbes Infect. 4:529.
15. Lu, L., and D. G. Osmond. 2000. Apoptosis and its modulation during B lymphopoiesis in mouse bone marrow. Immunol. Rev. 175:158.
16. Plas, D. R., J. C. Rathmell, and C. B. Thompson. 2002. Homeostatic control of lymphocyte survival: potential origins and implications. Nat. Immun. 3:515.
17. Nakayama, K., I. Negishi, K. Kuida, Y. Shinkai, M. C. Louie, L. E. Fields, P. J. Lucas, V. Stewart, F. W. Alt, and D. Loh. 1993. Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice. Science 261:1584.
18. Motoyama, N., F. Wang, K. A. Roth, H. Sawa, K. Nakayama, I. Negishi, S. Senju, Q. Zhang, S. Fujii, and D. Y. Loh. 1995. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 267:1506.
19. Cassese, G., S. Lindenau, B. de Boer, S. Arce, A. Hauser, G. Riemekasten, C. Berek, F. Hiepe, V. Krenn, A. Radbruch, and R. A. Manz. 2001. Inflamed kidneys of NZB/W mice are a major site for the homeostasis of plasma cells. Eur. J. Immunol. 31:2726.
20. Manz, R., M. Assenmacher, E. Pfluger, S. Miltenyi, and A. Radbruch. 1995. Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix. Proc. Natl. Acad. Sci. USA 92:1921.
21. Grossmann, M., L. A. O'Reilly, R. Gugasyan, A. Strasser, J. M. Adams, and S. Gerondakis. 2000. The anti-apoptotic activities of Re1 and Re1A required during B-cell maturation involve the regulation of Bcl-2 expression. EMBO J. 19:6351.
22. Tomayko, M. M., and M. P. Cancro. 1998. Long-lived B cells are distinguished by elevated expression of A1. J. Immunol. 160:107.
23. 2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts. J. Exp. Med. 183:227.
24. Zhang, B., I. Gojo, and R. G. Fenton. 2002. Myeloid cell factor-1 is a critical survival factor for multiple myeloma. Blood 99:1885.
25. Degrassi, A., D. M. Hilbert, S. Rudikoff, A. O. Anderson, M. Potter, and H. G. Coon. 1993. In vitro culture of primary plasmacytomas requires stromal cell feeder layers. Proc. Natl. Acad. Sci. USA 90:2060.
26. Medina, F., C. Segundo, A. Campos-Caro, I. Gonzalez-Garcia, and J. A. Brieva. 2002. The heterogeneity shown by human plasma cells from tonsil, blood, and bone marrow reveals graded stages of increasing maturity, but local profiles of adhesion molecule expression. Blood 99:2154.
27. Brieva, J. A., E. Roldan, M. L. De la Sen, and C. Rodriguez. 1991. Human in vivo-induced spontaneous IgG-secreting cells from tonsil, blood and bone marrow exhibit different phenotype and functional level of maturation. Immunology 72:580.
28. Kopf, M., S. Herren, M. V. Wiles, M. B. Pepys, and M. H. Kosco-Vilbois. 1998. Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component. J. Exp. Med. 188:1895.
29. Manz, R. A., A. Thiel, and A. Radbruch. 1997. Lifetime of plasma cells in the bone marrow. Nature 388:133.
30. Smith, K. G., U. Weiss, K. Rajewsky, G. J. Nossal, and D. M. Tarlinton. 1994. Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers. Immunity 1:803.
31. Rahman, Z., H. Yoshikawa, Y. Nakajima, and K. Tasaka. 2001. Down-regulation of Pim-1 and Bcl-2 is accompanied with apoptosis of interleukin-6-depleted mouse B-cell hybridoma 7TD1 cells. Immunol. Lett. 75:199.
32. Brennan, F. R., J. K. O'Neill, S. J. Allen, C. Butter, G. Nuki, and D. Baker. 1999. CD44 is involved in selective leukocyte extravasation during inflammatory central nervous system disease. Immunology 98:427.
33. Horuk, R. 1998. Chemokines beyond inflammation. Nature 393:524.
34. Roldan, E., and J. A. Brieva. 1991. Terminal differentiation of human bone marrow cells capable of spontaneous and high-rate immunoglobulin secretion: role of bone marrow stromal cells and interleukin 6. Eur. J. Immunol. 21:2671.
35. Skibinski, G., A. Skibinska, G. D. Stewart, and K. James. 1998. Enhancement of terminal B lymphocyte differentiafion in vitro by fibroblast-like stromal cells from human spleen. Eur. J. Immunol. 28:3940.
36. Kawano, M., T. Hirano, T. Matsuda, T. Taga, Y. Horii, K. Iwato, H. Asaoku, B. Tang, O. Tanabe, H. Tanaka, et al. 1988. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature 332:83.
37. Bachmann, M. F., T. M. Kundig, H, Hengartner, and R. M. Zinkernagel. 1994. Regulation of IgG antibody titers by the amount persisting of immune-complexed antigen. Eur. J. Immunol. 24:2567.
38. Hargreaves, D. C., P. L. Hyman, T. T. Lu, V. N. Ngo, A. Bidgol, G. Suzuki, Y. R. Zou, D. R. Littman, and J. G. Cyster. 2001. A coordinated change in chemokine responsiveness guides plasma cell movements. J. Exp. Med. 194:45.
39. Hauser, A. E., G. F. Debes, S. Arce, G. Cassese, A. Hamann, A. Radbruch, and R. A. Manz. 2002. Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response. J. Immunol. 169:1277.
40. Lesley, J., R. Hyman, and P. W. Kincade. 1993. CD44 and its interaction with extracellular matrix. Adv. Immunol. 54:271.
41. Haynes, B. F., M. J. Telen, L. P. Hale, and S. M. Denning. 1989. CD44: a molecule involved in leukocyte adherence and T-cell activation. Immunol. Today 10:423.
42. Rafi, A., M. Nagarkatti, and P. S. Nagarkatti. 1997. Hyaluronate-CD44 interactions can induce murine B-cell activation. Blood 89:2901.
43. Uchiyama, H., B. A. Barut, A. F. Mohrbacher, D. Chauhan, and K. C. Anderson. 1993. Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion. Blood 82:3712.
44. Turner, C. A., Jr., D. H. Mack, and M. M. Davis. 1994. Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells. Cell 77:297.
45. Knodel, M., A. W. Kuss, D. Lindemann, I. Berberich, and A. Schimpl. 1999. Reversal of B limp-1-mediated apoptosis by A1, a member of the Bcl-2 family. Eur. J. Immunol. 29:2988.
46. Tsujimoto, T., I. A. Lisukov, N. Huang, M. S. Mahmoud, and M. M. Kawano. 1996. Plasma cells induce apoptosis of pre-B cells by interacting with bone marrow stromal cells. Blood 87:3375.
47. Kondo, M., and I. L. Weissman. 2000. Function of cytokines in lymphocyte development. Curr. Top. Microbiol. Immunol. 251:59.