Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3A in mouse liver

Free Radical Biology and Medicine

Volumn 37, Issue 1, 2004, Pages 10-22

  Xu, De Xiang ^a   Wei, Wei ^a   Sun, Mei Fang ^a   Wu, Cheng Yi ^a   Wang, Jian Ping ^a   Wei, Ling Zhen ^a   Zhou, Cheng Fan ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

AA; AG; ALL; Allopurinol; Aminoguanidine; Antioxidants; Ascorbic acid; cDNA; Complementary DNA; CYP3A; Cytochrome P450 3A; Dex; Dexamethasone; DPI; Free radicals; Kupffer cells; Lipopolysaccharide; Pregnane X receptor; Reactive oxygen species

Indexed keywords

DEXAMETHASONE; LIPOPOLYSACCHARIDE; MIFEPRISTONE; PHENOBARBITAL; PREGNANE X RECEPTOR; REACTIVE OXYGEN METABOLITE; RIFAMPICIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME DEGRADATION; FEMALE; GENE REPRESSION; GENE TARGETING; KUPFFER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP3A; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LIVER; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; OXIDOREDUCTASES, N-DEMETHYLATING; REACTIVE OXYGEN SPECIES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID;

STAPHYLOCOCCUS PHAGE 3A;

EID: 2942594009     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.03.021     Document Type: Article

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