ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 10, 2005, Pages 3788-3793

  Engelman, Jeffrey A ^a,b,c,d   Jänne, Pasi A ^c,d   Mermel, Craig ^a,b   Pearlberg, Joseph ^c,d   Mukohara, Toru ^c,d   Fleet, Christina ^d   Cichowski, Karen ^d   Johnson, Bruce E ^c,d   Cantley, Lewis C ^a,b,e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

Akt; EGF receptor

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 3; GEFITINIB; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHORT HAIRPIN RNA;

ARTICLE; CANCER CELL CULTURE; CELL MUTANT; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; HUMANS; LUNG NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-3;

EID: 14844366111     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0409773102     Document Type: Article

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