Interleukin-12-induced interferon-γ production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR)

Journal of Biological Chemistry

Volumn 280, Issue 2, 2005, Pages 1037-1043

  Kusaba, Hitoshi ^a   Ghosh, Paritosh ^a   Derin, Rachel ^a   Buchholz, Meredith ^a   Sasaki, Carl ^a   Madara, Karen ^a   Longo, Dan L ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; PATIENT TREATMENT; PROTEINS; RNA; SENSITIVITY ANALYSIS; SIGNALING;

MEDIATED INTERFERON (IFN); PHOSPHORYLATION; RAPAMYCIN TREATMENT; SIGNALING PATHWAYS;

CELLS;

CYCLOSPORIN A; GAMMA INTERFERON; INTERLEUKIN 12; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN C JUN; RAPAMYCIN; SMALL INTERFERING RNA; STAT3 PROTEIN; STAT4 PROTEIN;

ARTICLE; BLOOD; CONTROLLED STUDY; DRUG RESISTANCE; DRUG SENSITIVITY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE;

ANTIGENS, CD28; CELLS, CULTURED; CYCLOSPORINE; DNA-BINDING PROTEINS; HUMANS; INTERFERON TYPE II; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; PHOSPHORYLATION; PHOSPHOSERINE; PROMOTER REGIONS (GENETICS); PROTEIN KINASES; SIROLIMUS; STAT3 TRANSCRIPTION FACTOR; STAT4 TRANSCRIPTION FACTOR; T-LYMPHOCYTES; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 12544252206     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405204200     Document Type: Article

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