Interaction of human MUC1 and β-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells

Biochemical and Biophysical Research Communications

Volumn 315, Issue 2, 2004, Pages 471-476

  Li, Quan ^a,b   Ren, Jian ^a   Kufe, Donald ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

Jurkat T cells; Lck; MUC1; T cell receptor; ZAP 70; Catenin

Indexed keywords

BETA CATENIN; CD3 ANTIGEN; IONOMYCIN; MUCIN 1; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70;

ARTICLE; CELL ACTIVATION; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 0842288993     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.01.075     Document Type: Article

References (35)

1. Ligtenberg M., Buijs F., Vos H., Hilkens J. Suppression of cellular aggregation by high levels of episialin. Cancer Res. 52:1992;223-232.
2. Gendler S., Taylor-Papadimitriou J., Duhig T., Rothbard J., Burchell J.A. A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. J. Biol. Chem. 263:1988;12820-12823.
3. Siddiqui J., Abe M., Hayes D., Shani E., Yunis E., Kufe D. Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen. Proc. Natl. Acad. Sci. USA. 85:1988;2320-2323.
4. Merlo G., Siddiqui J., Cropp C., Liscia D.S., Lidereau R., Callahan R., Kufe D. DF3 tumor-associated antigen gene is located in a region on chromosome 1q frequently altered in primary human breast cancer. Cancer Res. 49:1989;6966-6971.
5. Kufe D., Inghirami G., Abe M., Hayes D., Justi-Wheeler H., Schlom J. Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma. 3:1984;223-232.
6. Delsol G., Gatter K.C., Stein H., Erber W.N., Pulford K.A., Zinne K., Mason D.Y. Human lymphoid cells express epithelial membrane antigen. Implications for diagnosis of human neoplasms. Lancet. 2:1984;1124-1129.
7. Takahashi T., Makiguchi Y., Hinoda Y., Kakiuchi H., Nakagawa N., Imai K., Yachi A. Expression of MUC-1 on myeloma cells and induction of HLA-unrestricted CTL against MUC1 from a multiple myeloma patient. J. Immunol. 153:1994;2102-2109.
8. Treon S.P., Mollick J.A., Urashima M., Teoh G., Chauhan D., Ogata A., Raje N., Hilgers J.H., Nadler L., Belch A.R., Pilarski L.M., Anderson K.C. Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone. Blood. 93:1999;1287-1298.
9. Dyomin V.G., Palanisamy N., Lloyd K.O., Dyomina K., Jhanwar S.C., Houldsworth J., Chaganti R.S. MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets. Blood. 95:2000;2666-2671.
10. Li Y., Chen W., Ren J., Yu W., Li Q., Yoshida K., Kufe D. DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7. Cancer Biol. Ther. 2:2003;187-193.
11. Li Y., Liu D., Chen D., Kharbanda S., Kufe D. Human DF3/MUC1 carcinoma-associated protein functions as an oncogene. Oncogene. 22:2003;6107-6110.
12. Huang L., Ren J., Chen D., Li Y., Kharbanda S., Kufe D. MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation. Cancer Biol. Ther. 2:2003;702-706.
13. Yamamoto M., Bharti A., Li Y., Kufe D. Interaction of the DF3/MUC1 breast carcinoma-associated antigen and β-catenin in cell adhesion. J. Biol. Chem. 272:1997;12492-12494.
14. Li Y., Kuwahara H., Ren J., Wen G., Kufe D. The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3β and β-catenin. J. Biol. Chem. 276:2001;6061-6064.
15. Li Y., Bharti A., Chen D., Gong J., Kufe D. Interaction of glycogen synthase kinase 3β with the DF3/MUC1 carcinoma-associated antigen and β-catenin. Mol. Cell. Biol. 18:1998;7216-7224.
16. Li Y., Yu W.-H., Ren J., Huang L., Kharbanda S., Loda M., Kufe D. Heregulin targets γ-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 protein. Mol. Cancer Res. 1:2003;765-775.
17. Wen Y., Caffrey T., Wheelock M., Johnson K., Hollingsworth M. Nuclear association of the cytoplasmic tail of MUC1 and β-catenin. J. Biol. Chem. 278:2003;38029-38039.
18. Zamoyska R., Basson A., Filby A., Legname G., Lovatt M., Seddon B. The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation. Immunol. Rev. 191:2003;107-118.
19. Li Y., Ren J., Yu W.-H., Li G., Kuwahara H., Yin L., Carraway K.L., Kufe D. The EGF receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin. J. Biol. Chem. 276:2001;35239-35242.
20. Rao N., Miyake S., Reddi A.L., Douillard P., Ghosh A.K., Dodge I.L., Zhou P., Fernandes N.D., Band H. Negative regulation of Lck by Cbl ubiquitin ligase. Proc. Natl. Acad. Sci. USA. 99:2002;3794-3799.
21. Rao N., Lupher M.L. Jr., Ota S., Reedquist K.A., Druker B.J., Band H. The linker phosphorylation site Tyr292 mediates the negative regulatory effect of Cbl on ZAP-70 in T cells. J. Immunol. 164:2000;4616-4626.
22. Lerner A., Clayton L.K., Mizoguchi E., Ghendler Y., van Ewijk W., Koyasu S., Bhan A.K., Reinherz E.L. Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death. EMBO J. 15:1996;5876-5887.
23. van Oers N.S., Killeen N., Weiss A. Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes. J. Exp. Med. 183:1996;1053-1062.
24. Huse M., Eck M.J., Harrison S.C. A Zn2+ ion links the cytoplasmic tail of CD4 and the N-terminal region of Lck. J. Biol. Chem. 273:1998;18729-18733.
25. Reth M. Antigen receptor tail clue. Nature. 338:1989;383-384.
26. Chen L., Ashe S., Brady W.A., Hellstrom I., Hellstrom K.E., Ledbetter J.A., McGowan P., Linsley P.S. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell. 71:1992;1093-1102.
27. Chan A.C., Dalton M., Johnson R., Kong G.H., Wang T., Thoma R., Kurosaki T. Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J. 14:1995;2499-2508.
28. Wange R.L., Guitian R., Isakov N., Watts J.D., Aebersold R., Samelson L.E. Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70. J. Biol. Chem. 270:1995;18730-18733.
29. Weiss A., Koretzky G., Schatzman R.C., Kadlecek T. Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1. Proc. Natl. Acad. Sci. USA. 88:1991;5484-5488.
30. Bustelo X.R., Barbacid M. Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells. Science. 256:1992;1196-1199.
31. Jackman J.K., Motto D.G., Sun Q., Tanemoto M., Turck C.W., Peltz G.A., Koretzky G.A., Findell P.R. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J. Biol. Chem. 270:1995;7029-7032.
32. Pandey P., Kharbanda S., Kufe D. Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein. Cancer Res. 55:1995;4000-4003.
33. Schroeder J., Thompson M., Gardner M., Gendler S. Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J. Biol. Chem. 276:2001;13057-13064.
34. Behrens J., von Kries J.P., Kühl M., Bruhn L., Wedlich D., Grosschedi R., Birchmeier W. Functional interaction of β-catenin with the transcription factor LEF-1. Nature. 382:1996;638-642.
35. Molenaar M., van de Wetering M., Oosterwegel M., Peterson-Maduro J., Godsave S., Korinek V., Roose J., Destrée O., Clevers H. Tcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos. Cell. 86:1996;391-399.