메뉴 건너뛰기




Volumn 54, Issue 12, 2005, Pages 1636-1643

Inhibition of the phosphatidylinositol 3′-kinase signaling pathway leads to decreased insulin-stimulated adiponectin secretion from 3T3-L1 adipocytes

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

EID: 28444494407     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2005.07.002     Document Type: Article
Times cited : (49)

References (57)
  • 2
    • 0348107406 scopus 로고    scopus 로고
    • Regulation of adipocytokines and insulin resistance
    • M. Fasshauer, and R. Paschke Regulation of adipocytokines and insulin resistance Diabetologia 46 2003 1594 1603
    • (2003) Diabetologia , vol.46 , pp. 1594-1603
    • Fasshauer, M.1    Paschke, R.2
  • 3
    • 4344607526 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism: Review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin
    • U. Meier, and A.M. Gressner Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin Clin Chem 50 2004 1511 1525
    • (2004) Clin Chem , vol.50 , pp. 1511-1525
    • Meier, U.1    Gressner, A.M.2
  • 4
    • 0029980285 scopus 로고    scopus 로고
    • CDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1)
    • K. Maeda, K. Okubo, I. Shimomura, T. Funahashi, Y. Matsuzawa, and K. Matsubara cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1) Biochem Biophys Res Commun 221 1996 286 289
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 286-289
    • Maeda, K.1    Okubo, K.2    Shimomura, I.3    Funahashi, T.4    Matsuzawa, Y.5    Matsubara, K.6
  • 5
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • P.E. Scherer, S. Williams, M. Fogliano, G. Baldini, and H.F. Lodish A novel serum protein similar to C1q, produced exclusively in adipocytes J Biol Chem 270 1995 26746 26749
    • (1995) J Biol Chem , vol.270 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 6
    • 17544382289 scopus 로고    scopus 로고
    • AdipoQ is a novel adipose-specific gene dysregulated in obesity
    • E. Hu, P. Liang, and B.M. Spiegelman AdipoQ is a novel adipose-specific gene dysregulated in obesity J Biol Chem 271 1996 10697 10703
    • (1996) J Biol Chem , vol.271 , pp. 10697-10703
    • Hu, E.1    Liang, P.2    Spiegelman, B.M.3
  • 7
    • 0029836585 scopus 로고    scopus 로고
    • Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma
    • Y. Nakano, T. Tobe, N.H. Choi-Miura, T. Mazda, and M. Tomita Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma J Biochem (Tokyo) 120 1996 803 812
    • (1996) J Biochem (Tokyo) , vol.120 , pp. 803-812
    • Nakano, Y.1    Tobe, T.2    Choi-Miura, N.H.3    Mazda, T.4    Tomita, M.5
  • 8
    • 9144263120 scopus 로고    scopus 로고
    • A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity
    • T.P. Combs, U.B. Pajvani, A.H. Berg, Y. Lin, L.A. Jelicks, and M. Laplante A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity Endocrinology 145 2004 367 383
    • (2004) Endocrinology , vol.145 , pp. 367-383
    • Combs, T.P.1    Pajvani, U.B.2    Berg, A.H.3    Lin, Y.4    Jelicks, L.A.5    Laplante, M.6
  • 9
    • 0041519355 scopus 로고    scopus 로고
    • Adiponectin: Systemic contributor to insulin sensitivity
    • U.B. Pajvani, and P.E. Scherer Adiponectin: systemic contributor to insulin sensitivity Curr Diab Rep 3 2003 207 213
    • (2003) Curr Diab Rep , vol.3 , pp. 207-213
    • Pajvani, U.B.1    Scherer, P.E.2
  • 10
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • T. Yamauchi, J. Kamon, H. Waki, Y. Terauchi, N. Kubota, and K. Hara The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity Nat Med 7 2001 941 946
    • (2001) Nat Med , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Terauchi, Y.4    Kubota, N.5    Hara, K.6
  • 12
    • 11144354080 scopus 로고    scopus 로고
    • Implications of plasma concentrations of adiponectin in patients with coronary artery disease
    • Y. Nakamura, K. Shimada, D. Fukuda, Y. Shimada, S. Ehara, and M. Hirose Implications of plasma concentrations of adiponectin in patients with coronary artery disease Heart 90 2004 528 533
    • (2004) Heart , vol.90 , pp. 528-533
    • Nakamura, Y.1    Shimada, K.2    Fukuda, D.3    Shimada, Y.4    Ehara, S.5    Hirose, M.6
  • 14
    • 10744232016 scopus 로고    scopus 로고
    • Decreased plasma concentration of a novel anti-inflammatory protein-adiponectin-in hypertensive men with coronary artery disease
    • Z. Dzielinska, A. Januszewicz, A. Wiecek, M. Demkow, M. Makowiecka-Ciesla, and A. Prejbisz Decreased plasma concentration of a novel anti-inflammatory protein-adiponectin-in hypertensive men with coronary artery disease Thromb Res 110 2003 365 369
    • (2003) Thromb Res , vol.110 , pp. 365-369
    • Dzielinska, Z.1    Januszewicz, A.2    Wiecek, A.3    Demkow, M.4    Makowiecka-Ciesla, M.5    Prejbisz, A.6
  • 15
  • 16
    • 0142216501 scopus 로고    scopus 로고
    • Plasma resistin, adiponectin and leptin levels in lean and obese subjects: Correlations with insulin resistance
    • J.V. Silha, M. Krsek, J.V. Skrha, P. Sucharda, B.L. Nyomba, and L.J. Murphy Plasma resistin, adiponectin and leptin levels in lean and obese subjects: correlations with insulin resistance Eur J Endocrinol 149 2003 331 335
    • (2003) Eur J Endocrinol , vol.149 , pp. 331-335
    • Silha, J.V.1    Krsek, M.2    Skrha, J.V.3    Sucharda, P.4    Nyomba, B.L.5    Murphy, L.J.6
  • 17
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • K. Hotta, T. Funahashi, N.L. Bodkin, H.K. Ortmeyer, Y. Arita, and B.C. Hansen Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys Diabetes 50 2001 1126 1133
    • (2001) Diabetes , vol.50 , pp. 1126-1133
    • Hotta, K.1    Funahashi, T.2    Bodkin, N.L.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6
  • 18
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
    • C. Weyer, T. Funahashi, S. Tanaka, K. Hotta, Y. Matsuzawa, and R.E. Pratley Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia J Clin Endocrinol Metab 86 2001 1930 1935
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3    Hotta, K.4    Matsuzawa, Y.5    Pratley, R.E.6
  • 19
    • 0037677604 scopus 로고    scopus 로고
    • Adiponectin expression from human adipose tissue: Relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression
    • P.A. Kern, G.B. Di Gregorio, T. Lu, N. Rassouli, and G. Ranganathan Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression Diabetes 52 2003 1779 1785
    • (2003) Diabetes , vol.52 , pp. 1779-1785
    • Kern, P.A.1    Di Gregorio, G.B.2    Lu, T.3    Rassouli, N.4    Ranganathan, G.5
  • 20
    • 0037840403 scopus 로고    scopus 로고
    • Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: A randomized trial
    • K. Esposito, A. Pontillo, C. Di Palo, G. Giugliano, M. Masella, and R. Marfella Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial JAMA 289 2003 1799 1804
    • (2003) JAMA , vol.289 , pp. 1799-1804
    • Esposito, K.1    Pontillo, A.2    Di Palo, C.3    Giugliano, G.4    Masella, M.5    Marfella, R.6
  • 21
    • 0037323424 scopus 로고    scopus 로고
    • Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy
    • C.L. Addy, A. Gavrila, S. Tsiodras, K. Brodovicz, A.W. Karchmer, and C.S. Mantzoros Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy J Clin Endocrinol Metab 88 2003 627 636
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 627-636
    • Addy, C.L.1    Gavrila, A.2    Tsiodras, S.3    Brodovicz, K.4    Karchmer, A.W.5    Mantzoros, C.S.6
  • 22
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
    • N. Ouchi, S. Kihara, Y. Arita, K. Maeda, H. Kuriyama, and Y. Okamoto Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin Circulation 100 1999 2473 2476
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 25
    • 0033538869 scopus 로고    scopus 로고
    • Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4
    • J.S. Bogan, and H.F. Lodish Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4 J Cell Biol 146 1999 609 620
    • (1999) J Cell Biol , vol.146 , pp. 609-620
    • Bogan, J.S.1    Lodish, H.F.2
  • 26
    • 0029929298 scopus 로고    scopus 로고
    • Diverse signaling pathways in the cellular actions of insulin
    • A.R. Saltiel Diverse signaling pathways in the cellular actions of insulin Am J Physiol 270 1996 E375 E385
    • (1996) Am J Physiol , vol.270
    • Saltiel, A.R.1
  • 27
    • 14444276528 scopus 로고    scopus 로고
    • Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects
    • A. Krook, J.P. Whitehead, S.P. Dobson, M.R. Griffiths, M. Ouwens, and C. Baker Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects J Biol Chem 272 1997 30208 30214
    • (1997) J Biol Chem , vol.272 , pp. 30208-30214
    • Krook, A.1    Whitehead, J.P.2    Dobson, S.P.3    Griffiths, M.R.4    Ouwens, M.5    Baker, C.6
  • 28
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
    • B. Cheatham, C.J. Vlahos, L. Cheatham, L. Wang, J. Blenis, and C.R. Kahn Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation Mol Cell Biol 14 1994 4902 4911
    • (1994) Mol Cell Biol , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 29
    • 18544363627 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells
    • M. Montagnani, I. Golovchenko, I. Kim, G.Y. Koh, M.L. Goalstone, and A.N. Mundhekar Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells J Biol Chem 277 2002 1794 1799
    • (2002) J Biol Chem , vol.277 , pp. 1794-1799
    • Montagnani, M.1    Golovchenko, I.2    Kim, I.3    Koh, G.Y.4    Goalstone, M.L.5    Mundhekar, A.N.6
  • 30
    • 0141866848 scopus 로고    scopus 로고
    • Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways
    • C.C. Wang, I. Gurevich, and B. Draznin Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways Diabetes 52 2003 2562 2569
    • (2003) Diabetes , vol.52 , pp. 2562-2569
    • Wang, C.C.1    Gurevich, I.2    Draznin, B.3
  • 31
    • 0032489036 scopus 로고    scopus 로고
    • Activation of the ras mitogen-activated protein kinase-ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin
    • C. Sutherland, M. Waltner-Law, L. Gnudi, B.B. Kahn, and D.K. Granner Activation of the ras mitogen-activated protein kinase-ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin J Biol Chem 273 1998 3198 3204
    • (1998) J Biol Chem , vol.273 , pp. 3198-3204
    • Sutherland, C.1    Waltner-Law, M.2    Gnudi, L.3    Kahn, B.B.4    Granner, D.K.5
  • 32
    • 0029924465 scopus 로고    scopus 로고
    • Expression of a dominant-negative Ras mutant does not affect stimulation of glucose uptake and glycogen synthesis by insulin
    • J. Dorrestijn, D.M. Ouwens, N. Van den Berghe, J.L. Bos, and J.A. Maassen Expression of a dominant-negative Ras mutant does not affect stimulation of glucose uptake and glycogen synthesis by insulin Diabetologia 39 1996 558 563
    • (1996) Diabetologia , vol.39 , pp. 558-563
    • Dorrestijn, J.1    Ouwens, D.M.2    Van Den Berghe, N.3    Bos, J.L.4    Maassen, J.A.5
  • 33
    • 0029131895 scopus 로고
    • Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin
    • D.F. Lazar, R.J. Wiese, M.J. Brady, C.C. Mastick, S.B. Waters, and K. Yamauchi Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin J Biol Chem 270 1995 20801 20807
    • (1995) J Biol Chem , vol.270 , pp. 20801-20807
    • Lazar, D.F.1    Wiese, R.J.2    Brady, M.J.3    Mastick, C.C.4    Waters, S.B.5    Yamauchi, K.6
  • 34
    • 0033913213 scopus 로고    scopus 로고
    • Signaling pathways in insulin action: Molecular targets of insulin resistance
    • J.E. Pessin, and A.R. Saltiel Signaling pathways in insulin action: molecular targets of insulin resistance J Clin Invest 106 2000 165 169
    • (2000) J Clin Invest , vol.106 , pp. 165-169
    • Pessin, J.E.1    Saltiel, A.R.2
  • 35
    • 0033968126 scopus 로고    scopus 로고
    • Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle
    • K. Cusi, K. Maezono, A. Osman, M. Pendergrass, M.E. Patti, and T. Pratipanawatr Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle J Clin Invest 105 2000 311 320
    • (2000) J Clin Invest , vol.105 , pp. 311-320
    • Cusi, K.1    Maezono, K.2    Osman, A.3    Pendergrass, M.4    Patti, M.E.5    Pratipanawatr, T.6
  • 36
    • 0032719024 scopus 로고    scopus 로고
    • Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
    • Z.Y. Jiang, Y.W. Lin, A. Clemont, E.P. Feener, K.D. Hein, and M. Igarashi Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats J Clin Invest 104 1999 447 457
    • (1999) J Clin Invest , vol.104 , pp. 447-457
    • Jiang, Z.Y.1    Lin, Y.W.2    Clemont, A.3    Feener, E.P.4    Hein, K.D.5    Igarashi, M.6
  • 37
    • 0038809142 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 in obesity and insulin resistance
    • P. Sartipy, and D.J. Loskutoff Monocyte chemoattractant protein 1 in obesity and insulin resistance Proc Natl Acad Sci U S A 100 2003 7265 7270
    • (2003) Proc Natl Acad Sci U S a , vol.100 , pp. 7265-7270
    • Sartipy, P.1    Loskutoff, D.J.2
  • 38
    • 0033536236 scopus 로고    scopus 로고
    • Insulin signaling in the arterial wall
    • W.A. Hsueh, and R.E. Law Insulin signaling in the arterial wall Am J Cardiol 84 1999 21J 24J
    • (1999) Am J Cardiol , vol.84
    • Hsueh, W.A.1    Law, R.E.2
  • 39
    • 0033539950 scopus 로고    scopus 로고
    • Hyperglycemia impairs the insulin signaling step between PI 3-kinase and Akt/PKB activations in ZDF rat liver
    • M. Nawano, K. Ueta, A. Oku, K. Arakawa, A. Saito, and M. Funaki Hyperglycemia impairs the insulin signaling step between PI 3-kinase and Akt/PKB activations in ZDF rat liver Biochem Biophys Res Commun 266 1999 252 256
    • (1999) Biochem Biophys Res Commun , vol.266 , pp. 252-256
    • Nawano, M.1    Ueta, K.2    Oku, A.3    Arakawa, K.4    Saito, A.5    Funaki, M.6
  • 40
    • 0030890580 scopus 로고    scopus 로고
    • Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus
    • C.M. Rondinone, L.M. Wang, P. Lonnroth, C. Wesslau, J.H. Pierce, and U. Smith Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus Proc Natl Acad Sci U S A 94 1997 4171 4175
    • (1997) Proc Natl Acad Sci U S a , vol.94 , pp. 4171-4175
    • Rondinone, C.M.1    Wang, L.M.2    Lonnroth, P.3    Wesslau, C.4    Pierce, J.H.5    Smith, U.6
  • 41
    • 0032762661 scopus 로고    scopus 로고
    • Insulin signaling and action in fat cells: Associations with insulin resistance and type 2 diabetes
    • U. Smith, M. Axelsen, E. Carvalho, B. Eliasson, P.A. Jansson, and C. Wesslau Insulin signaling and action in fat cells: associations with insulin resistance and type 2 diabetes Ann NY Acad Sci 892 1999 119 126
    • (1999) Ann NY Acad Sci , vol.892 , pp. 119-126
    • Smith, U.1    Axelsen, M.2    Carvalho, E.3    Eliasson, B.4    Jansson, P.A.5    Wesslau, C.6
  • 42
    • 1442326009 scopus 로고    scopus 로고
    • Discrimination between obesity and insulin resistance in the relationship with adiponectin
    • F. Abbasi, J.W. Chu, C. Lamendola, T. McLaughlin, J. Hayden, and G.M. Reaven Discrimination between obesity and insulin resistance in the relationship with adiponectin Diabetes 53 2004 585 590
    • (2004) Diabetes , vol.53 , pp. 585-590
    • Abbasi, F.1    Chu, J.W.2    Lamendola, C.3    McLaughlin, T.4    Hayden, J.5    Reaven, G.M.6
  • 43
    • 0141669120 scopus 로고    scopus 로고
    • Plasma levels of adiponectin are associated with insulin resistance and serum levels of triglyceride in Japanese metabolically obese, normal-weight men with normal glucose tolerance
    • A. Katsuki, Y. Sumida, H. Urakawa, E.C. Gabazza, S. Murashima, and K. Matsumoto Plasma levels of adiponectin are associated with insulin resistance and serum levels of triglyceride in Japanese metabolically obese, normal-weight men with normal glucose tolerance Diabetes Care 26 2003 2964 2965
    • (2003) Diabetes Care , vol.26 , pp. 2964-2965
    • Katsuki, A.1    Sumida, Y.2    Urakawa, H.3    Gabazza, E.C.4    Murashima, S.5    Matsumoto, K.6
  • 44
    • 0036349010 scopus 로고    scopus 로고
    • Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population
    • Y. Yamamoto, H. Hirose, I. Saito, M. Tomita, M. Taniyama, and K. Matsubara Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population Clin Sci (Lond) 103 2002 137 142
    • (2002) Clin Sci (Lond) , vol.103 , pp. 137-142
    • Yamamoto, Y.1    Hirose, H.2    Saito, I.3    Tomita, M.4    Taniyama, M.5    Matsubara, K.6
  • 46
    • 0037180472 scopus 로고    scopus 로고
    • Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice
    • Y. Okamoto, S. Kihara, N. Ouchi, M. Nishida, Y. Arita, and M. Kumada Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice Circulation 106 2002 2767 2770
    • (2002) Circulation , vol.106 , pp. 2767-2770
    • Okamoto, Y.1    Kihara, S.2    Ouchi, N.3    Nishida, M.4    Arita, Y.5    Kumada, M.6
  • 47
    • 0037462684 scopus 로고    scopus 로고
    • Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis
    • T. Yamauchi, J. Kamon, H. Waki, Y. Imai, N. Shimozawa, and K. Hioki Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis J Biol Chem 278 2003 2461 2468
    • (2003) J Biol Chem , vol.278 , pp. 2461-2468
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Imai, Y.4    Shimozawa, N.5    Hioki, K.6
  • 48
    • 0036930844 scopus 로고    scopus 로고
    • Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: Effects of insulin and rosiglitazone
    • H. Motoshima, X. Wu, M.K. Sinha, V.E. Hardy, E.L. Rosato, and D.J. Barbot Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone J Clin Endocrinol Metab 87 2002 5662 5667
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5662-5667
    • Motoshima, H.1    Wu, X.2    Sinha, M.K.3    Hardy, V.E.4    Rosato, E.L.5    Barbot, D.J.6
  • 49
    • 0023736417 scopus 로고
    • The insulin receptor and the molecular mechanism of insulin action
    • C.R. Kahn, and M.F. White The insulin receptor and the molecular mechanism of insulin action J Clin Invest 82 1988 1151 1156
    • (1988) J Clin Invest , vol.82 , pp. 1151-1156
    • Kahn, C.R.1    White, M.F.2
  • 50
    • 0027249346 scopus 로고
    • Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase
    • F. Kanai, K. Ito, M. Todaka, H. Hayashi, S. Kamohara, and K. Ishii Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase Biochem Biophys Res Commun 195 1993 762 768
    • (1993) Biochem Biophys Res Commun , vol.195 , pp. 762-768
    • Kanai, F.1    Ito, K.2    Todaka, M.3    Hayashi, H.4    Kamohara, S.5    Ishii, K.6
  • 51
    • 0031852665 scopus 로고    scopus 로고
    • Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
    • A. Krook, R.A. Roth, X.J. Jiang, J.R. Zierath, and H. Wallberg-Henriksson Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects Diabetes 47 1998 1281 1286
    • (1998) Diabetes , vol.47 , pp. 1281-1286
    • Krook, A.1    Roth, R.A.2    Jiang, X.J.3    Zierath, J.R.4    Wallberg-Henriksson, H.5
  • 52
    • 0032698470 scopus 로고    scopus 로고
    • Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes
    • Y.B. Kim, S.E. Nikoulina, T.P. Ciaraldi, R.R. Henry, and B.B. Kahn Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes J Clin Invest 104 1999 733 741
    • (1999) J Clin Invest , vol.104 , pp. 733-741
    • Kim, Y.B.1    Nikoulina, S.E.2    Ciaraldi, T.P.3    Henry, R.R.4    Kahn, B.B.5
  • 53
    • 2042540707 scopus 로고    scopus 로고
    • Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance
    • M. Hazel, R.C. Cooksey, D. Jones, G. Parker, J.L. Neidigh, and B. Witherbee Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance Endocrinology 145 2004 2118 2128
    • (2004) Endocrinology , vol.145 , pp. 2118-2128
    • Hazel, M.1    Cooksey, R.C.2    Jones, D.3    Parker, G.4    Neidigh, J.L.5    Witherbee, B.6
  • 54
    • 0242413107 scopus 로고    scopus 로고
    • Adipocyte-selective reduction of the leptin receptors induced by antisense RNA leads to increased adiposity, dyslipidemia, and insulin resistance
    • J.N. Huan, J. Li, Y. Han, K. Chen, N. Wu, and A.Z. Zhao Adipocyte-selective reduction of the leptin receptors induced by antisense RNA leads to increased adiposity, dyslipidemia, and insulin resistance J Biol Chem 278 2003 45638 45650
    • (2003) J Biol Chem , vol.278 , pp. 45638-45650
    • Huan, J.N.1    Li, J.2    Han, Y.3    Chen, K.4    Wu, N.5    Zhao, A.Z.6
  • 55
    • 1642299047 scopus 로고    scopus 로고
    • Adipose tissue adiponectin production and adiponectin serum concentration in human obesity and insulin resistance
    • J. Hoffstedt, E. Arvidsson, E. Sjolin, K. Wahlen, and P. Arner Adipose tissue adiponectin production and adiponectin serum concentration in human obesity and insulin resistance J Clin Endocrinol Metab 89 2004 1391 1396
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1391-1396
    • Hoffstedt, J.1    Arvidsson, E.2    Sjolin, E.3    Wahlen, K.4    Arner, P.5
  • 56
    • 0035462629 scopus 로고    scopus 로고
    • PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
    • N. Maeda, M. Takahashi, T. Funahashi, S. Kihara, H. Nishizawa, and K. Kishida PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein Diabetes 50 2001 2094 2099
    • (2001) Diabetes , vol.50 , pp. 2094-2099
    • Maeda, N.1    Takahashi, M.2    Funahashi, T.3    Kihara, S.4    Nishizawa, H.5    Kishida, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.