메뉴 건너뛰기




Volumn 55, Issue 1, 2006, Pages 43-52

Energy restriction prevents the development of type 2 diabetes in Zucker diabetic fatty rats: Coordinated patterns of gene expression for energy metabolism in insulin-sensitive tissues and pancreatic islets determined by oligonucleotide microarray analysis

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE; FATTY ACID TRANSPORTER; GLUCAGON; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHORYLASE KINASE; PROTEIN; PROTEIN KINASE C; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE KINASE 4; UNCLASSIFIED DRUG;

EID: 28444476630     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2005.07.005     Document Type: Article
Times cited : (24)

References (53)
  • 1
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • W.C. Knowler, E. Barrett-Connor, and S.E. Fowler Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin N Engl J Med 346 2002 393 403
    • (2002) N Engl J Med , vol.346 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3
  • 2
    • 0035799806 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    • J. Tuomilehto, J. Lindstrom, and J.G. Eriksson Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance N Engl J Med 344 2001 1343 1350
    • (2001) N Engl J Med , vol.344 , pp. 1343-1350
    • Tuomilehto, J.1    Lindstrom, J.2    Eriksson, J.G.3
  • 4
    • 0037364022 scopus 로고    scopus 로고
    • The prevention of type 2 diabetes: Lifestyle change or pharmacotherapy? a challenge for the 21st century
    • R.W. Simpson, J.E. Shaw, and P.Z. Zimmet The prevention of type 2 diabetes: lifestyle change or pharmacotherapy? A challenge for the 21st century Diabetes Res Clin Pract 59 2003 165 180
    • (2003) Diabetes Res Clin Pract , vol.59 , pp. 165-180
    • Simpson, R.W.1    Shaw, J.E.2    Zimmet, P.Z.3
  • 5
    • 0035098360 scopus 로고    scopus 로고
    • Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice
    • R. Weindruch, T. Kayo, and C.K. Lee Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice J Nutr 131 2001 918S 923S
    • (2001) J Nutr , vol.131
    • Weindruch, R.1    Kayo, T.2    Lee, C.K.3
  • 6
    • 0347768064 scopus 로고    scopus 로고
    • Senescence-related changes in gene expression in muscle: Similarities and differences between mice and men
    • S. Welle, A. Brooks, and C.A. Thornton Senescence-related changes in gene expression in muscle: similarities and differences between mice and men Physiol Genomics 5 2001 67 73
    • (2001) Physiol Genomics , vol.5 , pp. 67-73
    • Welle, S.1    Brooks, A.2    Thornton, C.A.3
  • 7
    • 0036182137 scopus 로고    scopus 로고
    • Lipotoxic diseases
    • R.H. Unger Lipotoxic diseases Annu Rev Med 53 2002 319 336
    • (2002) Annu Rev Med , vol.53 , pp. 319-336
    • Unger, R.H.1
  • 8
    • 0036092239 scopus 로고    scopus 로고
    • Banting Lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
    • J.D. McGarry Banting Lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes Diabetes 51 2002 7 18
    • (2002) Diabetes , vol.51 , pp. 7-18
    • McGarry, J.D.1
  • 9
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • T. Nishikawa, D. Edelstein, and X.L. Du Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Nature 404 2000 787 790
    • (2000) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3
  • 10
    • 0036079637 scopus 로고    scopus 로고
    • Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity
    • F. Diraison, E. Dusserre, and H. Vidal Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity Am J Physiol Endocrinol Metab 282 2002 E46 E51
    • (2002) Am J Physiol Endocrinol Metab , vol.282
    • Diraison, F.1    Dusserre, E.2    Vidal, H.3
  • 11
    • 0037342152 scopus 로고    scopus 로고
    • Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility
    • H. Lan, M.E. Rabaglia, and J.P. Stoehr Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility Diabetes 52 2003 688 700
    • (2003) Diabetes , vol.52 , pp. 688-700
    • Lan, H.1    Rabaglia, M.E.2    Stoehr, J.P.3
  • 12
    • 0034633681 scopus 로고    scopus 로고
    • The expression of adipogenic genes is decreased in obesity and diabetes mellitus
    • S.T. Nadler, J.P. Stoehr, and K.L. Schueler The expression of adipogenic genes is decreased in obesity and diabetes mellitus Proc Natl Acad Sci U S A 97 2000 11371 11376
    • (2000) Proc Natl Acad Sci U S a , vol.97 , pp. 11371-11376
    • Nadler, S.T.1    Stoehr, J.P.2    Schueler, K.L.3
  • 13
    • 0033570119 scopus 로고    scopus 로고
    • Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus
    • I. Shimomura, Y. Bashmakov, and J.D. Horton Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus J Biol Chem 274 1999 30028 30032
    • (1999) J Biol Chem , vol.274 , pp. 30028-30032
    • Shimomura, I.1    Bashmakov, Y.2    Horton, J.D.3
  • 14
    • 0037341238 scopus 로고    scopus 로고
    • Glucose toxicity in beta-cells: Type 2 diabetes, good radicals gone bad, and the glutathione connection
    • R.P. Robertson, J. Harmon, and P.O. Tran Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection Diabetes 52 2003 581 587
    • (2003) Diabetes , vol.52 , pp. 581-587
    • Robertson, R.P.1    Harmon, J.2    Tran, P.O.3
  • 15
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
    • J.L. Evans, I.D. Goldfine, and B.A. Maddux Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes Endocr Rev 23 2002 599 622
    • (2002) Endocr Rev , vol.23 , pp. 599-622
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3
  • 16
    • 0034031083 scopus 로고    scopus 로고
    • Profiling of Zucker diabetic fatty rats in their progression to the overt diabetic state
    • G.J. Etgen, and B.A. Oldham Profiling of Zucker diabetic fatty rats in their progression to the overt diabetic state Metabolism 49 2000 684 688
    • (2000) Metabolism , vol.49 , pp. 684-688
    • Etgen, G.J.1    Oldham, B.A.2
  • 17
    • 0028874383 scopus 로고
    • Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat
    • Y. Tokuyama, J. Sturis, and A.M. DePaoli Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat Diabetes 44 1995 1447 1457
    • (1995) Diabetes , vol.44 , pp. 1447-1457
    • Tokuyama, Y.1    Sturis, J.2    Depaoli, A.M.3
  • 18
    • 0014042613 scopus 로고
    • Method for the isolation of intact islets of Langerhans from the rat pancreas
    • P.E. Lacy, and M. Kostianovsky Method for the isolation of intact islets of Langerhans from the rat pancreas Diabetes 16 1967 35 39
    • (1967) Diabetes , vol.16 , pp. 35-39
    • Lacy, P.E.1    Kostianovsky, M.2
  • 19
    • 0034751632 scopus 로고    scopus 로고
    • The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: Studies using high density oligonucleotide microarray
    • J. Xiao, S. Gregersen, and M. Kruhoffer The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: studies using high density oligonucleotide microarray Endocrinology 142 2001 4777 4784
    • (2001) Endocrinology , vol.142 , pp. 4777-4784
    • Xiao, J.1    Gregersen, S.2    Kruhoffer, M.3
  • 20
    • 0034714499 scopus 로고    scopus 로고
    • Gene expression profiling: Monitoring transcription and translation products using DNA microarrays and proteomics
    • J.E. Celis, M. Kruhoffer, and I. Gromova Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics FEBS Lett 480 2000 2 16
    • (2000) FEBS Lett , vol.480 , pp. 2-16
    • Celis, J.E.1    Kruhoffer, M.2    Gromova, I.3
  • 22
    • 0037590376 scopus 로고    scopus 로고
    • The limit fold change model: A practical approach for selecting differentially expressed genes from microarray data
    • D.M. Mutch, A. Berger, and R. Mansourian The limit fold change model: a practical approach for selecting differentially expressed genes from microarray data BMC Bioinformatics 3 2002 17
    • (2002) BMC Bioinformatics , vol.3 , pp. 17
    • Mutch, D.M.1    Berger, A.2    Mansourian, R.3
  • 23
    • 0034900072 scopus 로고    scopus 로고
    • Please pass the chips: Genomic insights into obesity and diabetes
    • S.T. Nadler, and A.D. Attie Please pass the chips: genomic insights into obesity and diabetes J Nutr 131 2001 2078 2081
    • (2001) J Nutr , vol.131 , pp. 2078-2081
    • Nadler, S.T.1    Attie, A.D.2
  • 25
    • 18344406192 scopus 로고    scopus 로고
    • DNA microarray analysis of genes differentially expressed in diet-induced (cafeteria) obese rats
    • I.P. Lopez, A. Marti, and F.I. Milagro DNA microarray analysis of genes differentially expressed in diet-induced (cafeteria) obese rats Obes Res 11 2003 188 194
    • (2003) Obes Res , vol.11 , pp. 188-194
    • Lopez, I.P.1    Marti, A.2    Milagro, F.I.3
  • 26
    • 0037369166 scopus 로고    scopus 로고
    • Microarray expression analysis of effects of exercise training: Increase in atrial MLC-1 in rat ventricles
    • G.M. Diffee, E.A. Seversen, and T.D. Stein Microarray expression analysis of effects of exercise training: increase in atrial MLC-1 in rat ventricles Am J Physiol Heart Circ Physiol 284 2003 H830 H837
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Diffee, G.M.1    Seversen, E.A.2    Stein, T.D.3
  • 27
    • 0036702238 scopus 로고    scopus 로고
    • Microarray analysis of diet-induced alterations in gene expression in the ACI rat prostate
    • N. Reyes, M. Iatropoulos, and A. Mittelman Microarray analysis of diet-induced alterations in gene expression in the ACI rat prostate Eur J Cancer Prev 11 Suppl 2 2002 S37 S42
    • (2002) Eur J Cancer Prev , vol.11 , Issue.2 SUPPL.
    • Reyes, N.1    Iatropoulos, M.2    Mittelman, A.3
  • 28
    • 0036871371 scopus 로고    scopus 로고
    • Gene expression during acute allograft rejection: Novel statistical analysis of microarray data
    • M. Stegall, W. Park, and D. Kim Gene expression during acute allograft rejection: novel statistical analysis of microarray data Am J Transplant 2 2002 913 925
    • (2002) Am J Transplant , vol.2 , pp. 913-925
    • Stegall, M.1    Park, W.2    Kim, D.3
  • 29
    • 0036674150 scopus 로고    scopus 로고
    • Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: A study of the transcription profile with complementary DNA microarray
    • N. Yajima, M. Masuda, and M. Miyazaki Oxidative stress is involved in the development of experimental abdominal aortic aneurysm: a study of the transcription profile with complementary DNA microarray J Vasc Surg 36 2002 379 385
    • (2002) J Vasc Surg , vol.36 , pp. 379-385
    • Yajima, N.1    Masuda, M.2    Miyazaki, M.3
  • 30
    • 0036342781 scopus 로고    scopus 로고
    • Energy metabolism pathways in rat muscle under conditions of simulated microgravity
    • T. Stein, M. Schluter, and A. Galante Energy metabolism pathways in rat muscle under conditions of simulated microgravity J Nutr Biochem 13 2002 471
    • (2002) J Nutr Biochem , vol.13 , pp. 471
    • Stein, T.1    Schluter, M.2    Galante, A.3
  • 31
    • 0033958461 scopus 로고    scopus 로고
    • Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model
    • Z.W. Man, T. Hirashima, and S. Mori Decrease in triglyceride accumulation in tissues by restricted diet and improvement of diabetes in Otsuka Long-Evans Tokushima fatty rats, a non-insulin-dependent diabetes model Metabolism 49 2000 108 114
    • (2000) Metabolism , vol.49 , pp. 108-114
    • Man, Z.W.1    Hirashima, T.2    Mori, S.3
  • 32
    • 0025750835 scopus 로고
    • Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise. the 6-year Malmo feasibility study
    • K.F. Eriksson, and F. Lindgarde Prevention of type 2 (non-insulin- dependent) diabetes mellitus by diet and physical exercise. The 6-year Malmo feasibility study Diabetologia 34 1991 891 898
    • (1991) Diabetologia , vol.34 , pp. 891-898
    • Eriksson, K.F.1    Lindgarde, F.2
  • 33
    • 0033972763 scopus 로고    scopus 로고
    • Effect of dietary fat on the development of non-insulin dependent diabetes mellitus in obese Zucker diabetic fatty male and female rats
    • J.P. Corsetti, J.D. Sparks, and R.G. Peterson Effect of dietary fat on the development of non-insulin dependent diabetes mellitus in obese Zucker diabetic fatty male and female rats Atherosclerosis 148 2000 231 241
    • (2000) Atherosclerosis , vol.148 , pp. 231-241
    • Corsetti, J.P.1    Sparks, J.D.2    Peterson, R.G.3
  • 34
    • 0036217052 scopus 로고    scopus 로고
    • Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
    • G.F. Lewis, A. Carpentier, and K. Adeli Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes Endocr Rev 23 2002 201 229
    • (2002) Endocr Rev , vol.23 , pp. 201-229
    • Lewis, G.F.1    Carpentier, A.2    Adeli, K.3
  • 35
    • 0035345532 scopus 로고    scopus 로고
    • Skeletal muscle triglyceride. An aspect of regional adiposity and insulin resistance
    • D.E. Kelley, and B.H. Goodpaster Skeletal muscle triglyceride. An aspect of regional adiposity and insulin resistance Diabetes Care 24 2001 933 941
    • (2001) Diabetes Care , vol.24 , pp. 933-941
    • Kelley, D.E.1    Goodpaster, B.H.2
  • 37
    • 0036584955 scopus 로고    scopus 로고
    • Skeletal muscle uncoupling protein 3 (UCP3): Mitochondrial uncoupling protein in search of a function
    • P. Schrauwen Skeletal muscle uncoupling protein 3 (UCP3): mitochondrial uncoupling protein in search of a function Curr Opin Clin Nutr Metab Care 5 2002 265 270
    • (2002) Curr Opin Clin Nutr Metab Care , vol.5 , pp. 265-270
    • Schrauwen, P.1
  • 38
    • 0035133171 scopus 로고    scopus 로고
    • Physiological role of UCP3 may be export of fatty acids from mitochondria when fatty acid oxidation predominates: An hypothesis
    • J. Himms-Hagen, and M.E. Harper Physiological role of UCP3 may be export of fatty acids from mitochondria when fatty acid oxidation predominates: an hypothesis Exp Biol Med (Maywood) 226 2001 78 84
    • (2001) Exp Biol Med (Maywood) , vol.226 , pp. 78-84
    • Himms-Hagen, J.1    Harper, M.E.2
  • 39
    • 0032792498 scopus 로고    scopus 로고
    • Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes
    • P. Wu, K. Inskeep, and M.M. Bowker-Kinley Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes Diabetes 48 1999 1593 1599
    • (1999) Diabetes , vol.48 , pp. 1593-1599
    • Wu, P.1    Inskeep, K.2    Bowker-Kinley, M.M.3
  • 40
    • 0036487233 scopus 로고    scopus 로고
    • Alterations of the circadian clock in the heart by streptozotocin-induced diabetes
    • M.E. Young, C.R. Wilson, and P. Razeghi Alterations of the circadian clock in the heart by streptozotocin-induced diabetes J Mol Cell Cardiol 34 2002 223 231
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 223-231
    • Young, M.E.1    Wilson, C.R.2    Razeghi, P.3
  • 41
    • 0033673994 scopus 로고    scopus 로고
    • Modulation of insulin signaling by protein tyrosine phosphatases
    • M. Elchebly, A. Cheng, and M.L. Tremblay Modulation of insulin signaling by protein tyrosine phosphatases J Mol Med 78 2000 473 482
    • (2000) J Mol Med , vol.78 , pp. 473-482
    • Elchebly, M.1    Cheng, A.2    Tremblay, M.L.3
  • 42
    • 0032577051 scopus 로고    scopus 로고
    • The Croonian Lecture 1997. the phosphorylation of proteins on tyrosine: Its role in cell growth and disease
    • T. Hunter The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease Philos Trans R Soc Lond B Biol Sci 353 1998 583 605
    • (1998) Philos Trans R Soc Lond B Biol Sci , vol.353 , pp. 583-605
    • Hunter, T.1
  • 43
    • 0036868797 scopus 로고    scopus 로고
    • Glucose-stimulated signaling pathways in biphasic insulin secretion
    • S.G. Straub, and G.W. Sharp Glucose-stimulated signaling pathways in biphasic insulin secretion Diabetes Metab Res Rev 18 2002 451 463
    • (2002) Diabetes Metab Res Rev , vol.18 , pp. 451-463
    • Straub, S.G.1    Sharp, G.W.2
  • 44
    • 0036311534 scopus 로고    scopus 로고
    • Recommended testing in diabetes research
    • E.J. Verspohl Recommended testing in diabetes research Planta Med 68 2002 581 590
    • (2002) Planta Med , vol.68 , pp. 581-590
    • Verspohl, E.J.1
  • 45
    • 0032587240 scopus 로고    scopus 로고
    • The role of TNFalpha and TNF receptors in obesity and insulin resistance
    • G.S. Hotamisligil The role of TNFalpha and TNF receptors in obesity and insulin resistance J Intern Med 245 1999 621 625
    • (1999) J Intern Med , vol.245 , pp. 621-625
    • Hotamisligil, G.S.1
  • 46
    • 0033815090 scopus 로고    scopus 로고
    • Expression of tumor necrosis factor-alpha-converting enzyme and tumor necrosis factor-alpha in human myocarditis
    • M. Satoh, M. Nakamura, H. Satoh, H. Saitoh, I. Segawa, and K. Hiramori Expression of tumor necrosis factor-alpha-converting enzyme and tumor necrosis factor-alpha in human myocarditis J Am Coll Cardiol 36 2000 1288 1294
    • (2000) J Am Coll Cardiol , vol.36 , pp. 1288-1294
    • Satoh, M.1    Nakamura, M.2    Satoh, H.3    Saitoh, H.4    Segawa, I.5    Hiramori, K.6
  • 47
    • 0036616582 scopus 로고    scopus 로고
    • Identifying the links between obesity, insulin resistance and beta-cell function: Potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes
    • A.S. Greenberg, and M.L. McDaniel Identifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes Eur J Clin Invest 32 Suppl 3 2002 24 34
    • (2002) Eur J Clin Invest , vol.32 , Issue.3 SUPPL. , pp. 24-34
    • Greenberg, A.S.1    McDaniel, M.L.2
  • 48
    • 0028942913 scopus 로고
    • Is caloric restriction effective in preventing diabetes mellitus in the Otsuka Long Evans Tokushima fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus?
    • N. Okauchi, A. Mizuno, and S. Yoshimoto Is caloric restriction effective in preventing diabetes mellitus in the Otsuka Long Evans Tokushima fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus? Diabetes Res Clin Pract 27 1995 97 106
    • (1995) Diabetes Res Clin Pract , vol.27 , pp. 97-106
    • Okauchi, N.1    Mizuno, A.2    Yoshimoto, S.3
  • 49
    • 0036549790 scopus 로고    scopus 로고
    • Gene expression in skeletal muscle
    • G. Goldspink Gene expression in skeletal muscle Biochem Soc Trans 30 2002 285 290
    • (2002) Biochem Soc Trans , vol.30 , pp. 285-290
    • Goldspink, G.1
  • 50
    • 0036632466 scopus 로고    scopus 로고
    • Islet redox stress: The manifold toxicities of insulin resistance, metabolic syndrome and amylin derived islet amyloid in type 2 diabetes mellitus
    • M.R. Hayden, and S.C. Tyagi Islet redox stress: the manifold toxicities of insulin resistance, metabolic syndrome and amylin derived islet amyloid in type 2 diabetes mellitus JOP 3 2002 86 108
    • (2002) JOP , vol.3 , pp. 86-108
    • Hayden, M.R.1    Tyagi, S.C.2
  • 51
    • 0037767984 scopus 로고    scopus 로고
    • Effects of interleukin-15 on suppression of rat pancreatic islets in vitro induced by proinflammatory cytokines
    • J. Wallstrom, A. Andersson, and S. Sandler Effects of interleukin-15 on suppression of rat pancreatic islets in vitro induced by proinflammatory cytokines Immunol Lett 88 2003 141 145
    • (2003) Immunol Lett , vol.88 , pp. 141-145
    • Wallstrom, J.1    Andersson, A.2    Sandler, S.3
  • 52
    • 0020046730 scopus 로고
    • Stimulatory effect of beta-hydroxybutyrate on the release of somatostatin from the isolated pancreas of normal and streptozotocin-diabetic dogs
    • K. Hermansen Stimulatory effect of beta-hydroxybutyrate on the release of somatostatin from the isolated pancreas of normal and streptozotocin-diabetic dogs Diabetes 31 1982 270 274
    • (1982) Diabetes , vol.31 , pp. 270-274
    • Hermansen, K.1
  • 53
    • 0037390423 scopus 로고    scopus 로고
    • Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines
    • V. Lilla, G. Webb, and K. Rickenbach Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines Endocrinology 144 2003 1368 1379
    • (2003) Endocrinology , vol.144 , pp. 1368-1379
    • Lilla, V.1    Webb, G.2    Rickenbach, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.