-
1
-
-
0031108103
-
Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing
-
Baumeister R, Leimer U, Zweckbronner I, Jakubek C, Grunberg J, and Haass C. Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing. Genes Funct 1: 149-159, 1997.
-
(1997)
Genes Funct
, vol.1
, pp. 149-159
-
-
Baumeister, R.1
Leimer, U.2
Zweckbronner, I.3
Jakubek, C.4
Grunberg, J.5
Haass, C.6
-
2
-
-
0032972922
-
Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice
-
Begley JG, Duan W, Chan S, Duff K, and Mattson MP. Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice. J Neurochem 72: 1030-1039, 1999.
-
(1999)
J Neurochem
, vol.72
, pp. 1030-1039
-
-
Begley, J.G.1
Duan, W.2
Chan, S.3
Duff, K.4
Mattson, M.P.5
-
3
-
-
0037474287
-
Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta APP
-
Cai D, Leem JY, Greenfield JP, Wang P, Wang R, Lopes KO, Kim SH, Zheng H, Greengard P, Sisodia SS, Thinakaran G, and Xu H. Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta APP. J Biol Chem 278: 3446-3454, 2002.
-
(2002)
J Biol Chem
, vol.278
, pp. 3446-3454
-
-
Cai, D.1
Leem, J.Y.2
Greenfield, J.P.3
Wang, P.4
Wang, R.5
Lopes, K.O.6
Kim, S.H.7
Zheng, H.8
Greengard, P.9
Sisodia, S.S.10
Thinakaran, G.11
Xu, H.12
-
4
-
-
0032588572
-
2+ channels and snare proteins in neurotransmitter release
-
2+ channels and snare proteins in neurotransmitter release. Ann NY Acad Sci 868: 159, 1999.
-
(1999)
Ann NY Acad Sci
, vol.868
, pp. 159
-
-
Catterall, W.A.1
-
6
-
-
0030293854
-
Protein topology of presenilin 1
-
Doan A, Thinakaran G, Borchelt DR, Slunt HH, Ratovitsky T, Podlisny M, Selkoe DJ, Seeger M, Gandy SE, Price DL, and Sisodia SS. Protein topology of presenilin 1. Neuron 17: 1023-1030, 1996.
-
(1996)
Neuron
, vol.17
, pp. 1023-1030
-
-
Doan, A.1
Thinakaran, G.2
Borchelt, D.R.3
Slunt, H.H.4
Ratovitsky, T.5
Podlisny, M.6
Selkoe, D.J.7
Seeger, M.8
Gandy, S.E.9
Price, D.L.10
Sisodia, S.S.11
-
7
-
-
18244391974
-
Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces
-
Feng R, Rampon C, Tang YP, Shrom D, Jin J, Kyin M, Sopher B, Miller MW, Ware CB, Martin GM, Kim SH, Langdon RB, Sisodia SS, and Tsien JZ. Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces. Neuron 32: 911-926, 2001.
-
(2001)
Neuron
, vol.32
, pp. 911-926
-
-
Feng, R.1
Rampon, C.2
Tang, Y.P.3
Shrom, D.4
Jin, J.5
Kyin, M.6
Sopher, B.7
Miller, M.W.8
Ware, C.B.9
Martin, G.M.10
Kim, S.H.11
Langdon, R.B.12
Sisodia, S.S.13
Tsien, J.Z.14
-
9
-
-
0033087854
-
Neuromodulation, development and synaptic plasticity
-
Foehring RC and Lorenzon NM. Neuromodulation, development and synaptic plasticity. Can J Exp Psychol 53: 45-64, 1999.
-
(1999)
Can J Exp Psychol
, vol.53
, pp. 45-64
-
-
Foehring, R.C.1
Lorenzon, N.M.2
-
10
-
-
0024467562
-
Calcium and polyphosphoinositide control of cytoskeletal dynamics
-
Forscher P. Calcium and polyphosphoinositide control of cytoskeletal dynamics. Trends Neuroscl 12: 468-474, 1989.
-
(1989)
Trends Neuroscl
, vol.12
, pp. 468-474
-
-
Forscher, P.1
-
11
-
-
0029031268
-
Calcium regulation of gene expression in neurons: The mode of entry matters
-
Gallin WJ and Greenberg ME. Calcium regulation of gene expression in neurons: The mode of entry matters. Curr Opin Neurobiol 5: 367-374, 1995.
-
(1995)
Curr Opin Neurobiol
, vol.5
, pp. 367-374
-
-
Gallin, W.J.1
Greenberg, M.E.2
-
12
-
-
0033016172
-
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
-
Guo Q, Fu W, Sopher BL, Miller MW, Ware CB, Martin GM, and Mattson MP. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat Med 5: 101-106, 1999a.
-
(1999)
Nat Med
, vol.5
, pp. 101-106
-
-
Guo, Q.1
Fu, W.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
13
-
-
0030891662
-
Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide
-
Guo Q, Furuakwa K, Sopher BL, Pham DG, Xie J, Robinson N, Martin GM, and Mattson MP. Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid β-peptide. Neuroreport 8: 379-383, 1996.
-
(1996)
Neuroreport
, vol.8
, pp. 379-383
-
-
Guo, Q.1
Furuakwa, K.2
Sopher, B.L.3
Pham, D.G.4
Xie, J.5
Robinson, N.6
Martin, G.M.7
Mattson, M.P.8
-
14
-
-
0033009194
-
Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: Central roles of superoxide production and caspase activation
-
Guo Q, Sebastion L, Sopher BL, Miller MW, Ware CB, Martin GM, and Mattson MP. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation. J Neurochem 72: 1019-1029, 1999b.
-
(1999)
J Neurochem
, vol.72
, pp. 1019-1029
-
-
Guo, Q.1
Sebastion, L.2
Sopher, B.L.3
Miller, M.W.4
Ware, C.B.5
Martin, G.M.6
Mattson, M.P.7
-
15
-
-
0030922421
-
Presenilins: Genes for life and death
-
Haass C. Presenilins: genes for life and death. Neuron 18: 687-690, 1997.
-
(1997)
Neuron
, vol.18
, pp. 687-690
-
-
Haass, C.1
-
16
-
-
0028263984
-
Differential phosphorylation of two size forms of the N-type calcium channel α1 subunit which have different COOH termini
-
Hell JW, Appleyard SM, Yokoyama CT, Warner C, and Catterall WA. Differential phosphorylation of two size forms of the N-type calcium channel α1 subunit which have different COOH termini. J Biol Chem 269: 7390-7396, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 7390-7396
-
-
Hell, J.W.1
Appleyard, S.M.2
Yokoyama, C.T.3
Warner, C.4
Catterall, W.A.5
-
17
-
-
0029915158
-
N-Methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons
-
Hell JW, Westenbroek RE, Breeze LJ, Wang KK, Chavkin C, and Catterall WA. N-Methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons. Proc Natl Acad Sci USA 93: 3362-3367, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3362-3367
-
-
Hell, J.W.1
Westenbroek, R.E.2
Breeze, L.J.3
Wang, K.K.4
Chavkin, C.5
Catterall, W.A.6
-
18
-
-
0027434862
-
Identification and differential subcellular localization of the neuronal class C and class D, L-type calcium channel alpha 1 subunits
-
Hell JW, Westenbroek RE, Warner C, Ahlijanian MK, Prystay WGMM, Snutch TP, and Catterall WA. Identification and differential subcellular localization of the neuronal class C and class D, L-type calcium channel alpha 1 subunits. J Biol Chem 123: 949-962, 1993.
-
(1993)
J Biol Chem
, vol.123
, pp. 949-962
-
-
Hell, J.W.1
Westenbroek, R.E.2
Warner, C.3
Ahlijanian, M.K.4
Wgmm, P.5
Snutch, T.P.6
Catterall, W.A.7
-
19
-
-
0037462753
-
Capacitative calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein
-
Herms J, Schneider I, Dewachter I, Caluwaerts N, Kretzschmar HA, and Van Leuven F. Capacitative calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein. J Biol Chem 278: 2484-2489, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 2484-2489
-
-
Herms, J.1
Schneider, I.2
Dewachter, I.3
Caluwaerts, N.4
Kretzschmar, H.A.5
Van Leuven, F.6
-
21
-
-
0028860060
-
Muscarinic receptors modulate N-, P-, and L-type calcium currents in rat striatal neurons through parallel pathways
-
Howe AR and Surmeier DJ. Muscarinic receptors modulate N-, P-, and L-type calcium currents in rat striatal neurons through parallel pathways. J Neurosci 15: 458-469, 1995.
-
(1995)
J Neurosci
, vol.15
, pp. 458-469
-
-
Howe, A.R.1
Surmeier, D.J.2
-
22
-
-
0037424348
-
The notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage
-
Ikeuchi T and Sisodia SS. The notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage. J Biol Chem 278: 7751-7754, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 7751-7754
-
-
Ikeuchi, T.1
Sisodia, S.S.2
-
23
-
-
0028179578
-
2+ mobilization is altered in fibroblasts from patients with Alzheimer's disease
-
2+ mobilization is altered in fibroblasts from patients with Alzheimer's disease. Proc Natl Acad Sci USA 91: 534-538, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 534-538
-
-
Ito, E.1
Oka, K.2
Etcheberrigaray, R.3
Nelson, T.J.4
McPhie, D.L.5
Tofel-Grehl, B.6
Gibson, G.E.7
Alkon, D.L.8
-
24
-
-
0344672942
-
APP processing and synaptic function
-
Kamenetz F, Tomita T, Hsieh H, Seabrook G, Borchelt DR, Iwatsubo T, Sisodia SS, and Malinow R. APP processing and synaptic function. Neuron 37: 925-937, 2003.
-
(2003)
Neuron
, vol.37
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Hsieh, H.3
Seabrook, G.4
Borchelt, D.R.5
Iwatsubo, T.6
Sisodia, S.S.7
Malinow, R.8
-
25
-
-
20744458852
-
Presenilin/γ-secretase-mediated cleavage of the voltage-gated sodium channel β2-subunit regulates cell adhesion and migration
-
Kim DY, MacKenzie Ingano LA, Carey BW, Pettingell WH, and Kovacs DM. Presenilin/γ-secretase-mediated cleavage of the voltage-gated sodium channel β2-subunit regulates cell adhesion and migration. J Biol Chem 280: 23251-23261, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 23251-23261
-
-
Kim, D.Y.1
MacKenzie Ingano, L.A.2
Carey, B.W.3
Pettingell, W.H.4
Kovacs, D.M.5
-
26
-
-
0029126336
-
Involvement of the carboxyl-terminal region of the α1 subunit in voltage-dependent inactivation of cardiac calcium channels
-
Klöckner U, Mikala G, Varadi M, Varadi G, and Schwartz A. Involvement of the carboxyl-terminal region of the α1 subunit in voltage-dependent inactivation of cardiac calcium channels. J Biol Chem 270: 17306-17310, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 17306-17310
-
-
Klöckner, U.1
Mikala, G.2
Varadi, M.3
Varadi, G.4
Schwartz, A.5
-
27
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's Disease
-
LaFerla FM. Calcium dyshomeostasis and intracellular signalling in Alzheimer's Disease. Nat Rev Neurosci 3: 862-872, 2002.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 862-872
-
-
Laferla, F.M.1
-
28
-
-
0037166349
-
Presenilin 1 is required for maturation and cell surface accumulation of nicastrin
-
Leem JY, Vijayan S, Han P, Cai D, Machura M, Lopes KO, Veselits ML, Xu H, and Thinakaran G. Presenilin 1 is required for maturation and cell surface accumulation of nicastrin. J Biol Chem 277: 19236-19240, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 19236-19240
-
-
Leem, J.Y.1
Vijayan, S.2
Han, P.3
Cai, D.4
Machura, M.5
Lopes, K.O.6
Veselits, M.L.7
Xu, H.8
Thinakaran, G.9
-
29
-
-
0034657414
-
Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice
-
Leissring MA, Akbari Y, Fanger CM, Cahalan MD, Mattson MP, and LaFerla FM. Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. J Cell Biol 149: 793-797, 2000.
-
(2000)
J Cell Biol
, vol.149
, pp. 793-797
-
-
Leissring, M.A.1
Akbari, Y.2
Fanger, C.M.3
Cahalan, M.D.4
Mattson, M.P.5
Laferla, F.M.6
-
30
-
-
0037007140
-
A physiologic signaling role for the gamma-secretase-derived intracellular fragment of APP
-
Leissring MA, Murphy MP, Mead TR, Akbari Y, Sugarman MC, Jannatipour M, Anliker B, Muller U, Saftig P, De Strooper B, Wolfe MS, Golde TE, and LaFerla FM. A physiologic signaling role for the gamma-secretase-derived intracellular fragment of APP. Proc Natl Acad Sci USA 99: 4697-4702, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4697-4702
-
-
Leissring, M.A.1
Murphy, M.P.2
Mead, T.R.3
Akbari, Y.4
Sugarman, M.C.5
Jannatipour, M.6
Anliker, B.7
Muller, U.8
Saftig, P.9
De Strooper, B.10
Wolfe, M.S.11
Golde, T.E.12
LaFerla, F.M.13
-
31
-
-
0032704888
-
Presenilin-2 mutations modulate amplitude and kinetics of inositol 1,4,5-trisphosphate-mediated calcium signals
-
Leissring MA, Parker I, and LaFerla FM. Presenilin-2 mutations modulate amplitude and kinetics of inositol 1,4,5-trisphosphate-mediated calcium signals. J Biol Chem 274: 32535-32538, 1999a.
-
(1999)
J Biol Chem
, vol.274
, pp. 32535-32538
-
-
Leissring, M.A.1
Parker, I.2
Laferla, F.M.3
-
32
-
-
0032972683
-
Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes
-
Leissring MA, Paul BA, Parker I, Cotman CW, and LaFerla FM. Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes. J Neurochem 72: 1061-1068, 1999b.
-
(1999)
J Neurochem
, vol.72
, pp. 1061-1068
-
-
Leissring, M.A.1
Paul, B.A.2
Parker, I.3
Cotman, C.W.4
Laferla, F.M.5
-
33
-
-
0029906585
-
Assessment of normal and mutant human presenilin function in Caenorhabditis elegant
-
Levitan D, Doyle TG, Brousseau D, Lee MK, Thinakaran G, Slunt HH, Sisodia SS, and Greenwald I. Assessment of normal and mutant human presenilin function in Caenorhabditis elegant. Proc Natl Acad Sci USA 93: 14940-14944, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14940-14944
-
-
Levitan, D.1
Doyle, T.G.2
Brousseau, D.3
Lee, M.K.4
Thinakaran, G.5
Slunt, H.H.6
Sisodia, S.S.7
Greenwald, I.8
-
34
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu C, Jondro PD, Schmidt SD, Wang K, Crowley AC, Fu, Y.-H, Guenette SY, Galas D, Nemens E, Wijsman EM, Bird TD, Schellenberg GD, and Tanzi RE. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269: 973-977, 1995.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
Crowley, A.C.11
Fu, Y.-H.12
Guenette, S.Y.13
Galas, D.14
Nemens, E.15
Wijsman, E.M.16
Bird, T.D.17
Schellenberg, G.D.18
Tanzi, R.E.19
-
35
-
-
0030293894
-
Membrane topology of the C. elegens SEL-12 presenilin
-
Li X and Greenwald I. Membrane topology of the C. elegens SEL-12 presenilin. Neuron 17: 1015-1021, 1996.
-
(1996)
Neuron
, vol.17
, pp. 1015-1021
-
-
Li, X.1
Greenwald, I.2
-
36
-
-
0028929317
-
Characterization of pharmacologically identified voltage-gated calcium channel currents in acutely isolated rat neocortical neurons. II. Postnatal development
-
Lorenzon NM and Foehring RC. Characterization of pharmacologically identified voltage-gated calcium channel currents in acutely isolated rat neocortical neurons. II. Postnatal development. J Neurophysiol 73: 1443-1451, 1995.
-
(1995)
J Neurophysiol
, vol.73
, pp. 1443-1451
-
-
Lorenzon, N.M.1
Foehring, R.C.2
-
37
-
-
18344380083
-
A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions
-
Marambaud P, Shioi J, Serban G, Georgakopoulos A, Sarner S, Nagy V, Baki L, Wen P, Efthimiopoulos S, Shao Z, Wisniewski T, and Robakis NK. A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. EMBO J 21: 1948-1956, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 1948-1956
-
-
Marambaud, P.1
Shioi, J.2
Serban, G.3
Georgakopoulos, A.4
Sarner, S.5
Nagy, V.6
Baki, L.7
Wen, P.8
Efthimiopoulos, S.9
Shao, Z.10
Wisniewski, T.11
Robakis, N.K.12
-
38
-
-
0031982670
-
Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's Disease
-
Mattson MP, Guo Q, Furuakwa K, and Pederson WA. Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's Disease. J Neurochem 70: 1-14, 1998.
-
(1998)
J Neurochem
, vol.70
, pp. 1-14
-
-
Mattson, M.P.1
Guo, Q.2
Furuakwa, K.3
Pederson, W.A.4
-
39
-
-
0037166319
-
Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain
-
May P, Reddy YK, and Herz J. Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain. J Biol Chem 277: 18736-18743, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 18736-18743
-
-
May, P.1
Reddy, Y.K.2
Herz, J.3
-
40
-
-
0032778263
-
Ion channels in presynaptic nerve terminals and control of transmitter release
-
Meir A, Ginsburg S, Butkevich A, Kachalsky SG, Kaiserman I, Ahdut R, Demirgoren S, and Rahamimoff R. Ion channels in presynaptic nerve terminals and control of transmitter release. Physiol Rev 79: 1019-1088, 1999.
-
(1999)
Physiol Rev
, vol.79
, pp. 1019-1088
-
-
Meir, A.1
Ginsburg, S.2
Butkevich, A.3
Kachalsky, S.G.4
Kaiserman, I.5
Ahdut, R.6
Demirgoren, S.7
Rahamimoff, R.8
-
41
-
-
0034882422
-
Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro
-
Nakajima M, Miura M, Aosaki T, and Shirasawa T. Deficiency of presenilin-1 increases calcium-dependent vulnerability of neurons to oxidative stress in vitro. J Neurochem 78: 807-814, 2001.
-
(2001)
J Neurochem
, vol.78
, pp. 807-814
-
-
Nakajima, M.1
Miura, M.2
Aosaki, T.3
Shirasawa, T.4
-
42
-
-
0000138540
-
Effects of PS1 deficiency on membrane protein trafficking in neurons
-
Naruse S, Thinakaran G, Luo JJ, Kusiak JW, Tomita T, Iwatsubo T, Qian X, Ginty DD, Price DL, Borchelt DR, Wong PC, and Sisodia SS. Effects of PS1 deficiency on membrane protein trafficking in neurons. Neuron 21: 1213-1221, 1998.
-
(1998)
Neuron
, vol.21
, pp. 1213-1221
-
-
Naruse, S.1
Thinakaran, G.2
Luo, J.J.3
Kusiak, J.W.4
Tomita, T.5
Iwatsubo, T.6
Qian, X.7
Ginty, D.D.8
Price, D.L.9
Borchelt, D.R.10
Wong, P.C.11
Sisodia, S.S.12
-
43
-
-
0035824391
-
Gamma-secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
-
Ni CY, Murphy MP, Golde TE, and Carpenter G. Gamma-secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science 294: 2179-2181, 2001.
-
(2001)
Science
, vol.294
, pp. 2179-2181
-
-
Ni, C.Y.1
Murphy, M.P.2
Golde, T.E.3
Carpenter, G.4
-
44
-
-
0032945724
-
Synaptic transmission and hippocampal long-term potential in transgenic mice expressing FAD-linked presenilin 1
-
Parent A, Linden DJ, Sisodia SS, and Borchelt DR. Synaptic transmission and hippocampal long-term potential in transgenic mice expressing FAD-linked presenilin 1. Neurobiol Dis 6: 56-62, 1999.
-
(1999)
Neurobiol Dis
, vol.6
, pp. 56-62
-
-
Parent, A.1
Linden, D.J.2
Sisodia, S.S.3
Borchelt, D.R.4
-
45
-
-
0028204224
-
Calcium ionophore increases amyloid β peptide production by cultured cells
-
Querfurth HW and Selkoe DJ. Calcium ionophore increases amyloid β peptide production by cultured cells. Biochemistry 33: 4550-4561, 1994.
-
(1994)
Biochemistry
, vol.33
, pp. 4550-4561
-
-
Querfurth, H.W.1
Selkoe, D.J.2
-
46
-
-
0028904492
-
2+ channel currents in rat cerebellar granule neurons
-
2+ channel currents in rat cerebellar granule neurons. J Neurosci 15: 2995-3012, 1995.
-
(1995)
J Neurosci
, vol.15
, pp. 2995-3012
-
-
Randall, A.1
Tsien, R.W.2
-
47
-
-
0035369784
-
2+ pools in neuronal signalling
-
2+ pools in neuronal signalling. Curr Opin Neurobiol 11: 306-311, 2001.
-
(2001)
Curr Opin Neurobiol
, vol.11
, pp. 306-311
-
-
Rizzuto, R.1
-
48
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
-
Rogaev EI, Sherrington E, Levesque G, Ikeda, M, and St. George-Hyslop, P. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376: 775-778, 1995.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, E.2
Levesque, G.3
Ikeda, M.4
St. George-Hyslop, P.5
-
49
-
-
0035974791
-
Stores not just for storage: Intracellular calcium release and synaptic plasticity
-
Rose CR and Konnerth A. Stores not just for storage: intracellular calcium release and synaptic plasticity. Neuron 31: 519-522, 2001.
-
(2001)
Neuron
, vol.31
, pp. 519-522
-
-
Rose, C.R.1
Konnerth, A.2
-
50
-
-
0035853828
-
Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation
-
Schneider I, Reverse D, Dewachter I, Ris L, Caluwaerts N, Kuiperi C, Gilis M, Geerts H, Kretzschmar HA, Godaux E, Moechars D, Van Leuven F, and Herms JW. Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation. J Biol Chem 276: 11539-11544, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 11539-11544
-
-
Schneider, I.1
Reverse, D.2
Dewachter, I.3
Ris, L.4
Caluwaerts, N.5
Kuiperi, C.6
Gilis, M.7
Geerts, H.8
Kretzschmar, H.A.9
Godaux, E.10
Moechars, D.11
Van Leuven, F.12
Herms, J.W.13
-
51
-
-
0031038918
-
Alzheimer's disease: Genotypes, phenotypes and treatments
-
Selkoe DJ. Alzheimer's disease: genotypes, phenotypes and treatments. Science 275: 630-631, 1997.
-
(1997)
Science
, vol.275
, pp. 630-631
-
-
Selkoe, D.J.1
-
52
-
-
0030779784
-
Skeletal and CNS defects in presenilin-1 deficient mice
-
Shen J, Bronson RT, Chen DF, Xia W, Selkoe DJ, and Tonegawa S. Skeletal and CNS defects in presenilin-1 deficient mice. Cell 89: 629-639, 1997.
-
(1997)
Cell
, vol.89
, pp. 629-639
-
-
Shen, J.1
Bronson, R.T.2
Chen, D.F.3
Xia, W.4
Selkoe, D.J.5
Tonegawa, S.6
-
53
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin, J.-F, Bruni AC, Montesi MP, Sorbi S, Rainero I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Silva HARD, Haines JL, Pericak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Romens JM, and George-Hyslop PHS. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375: 754-760, 1995.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.-F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainero, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.21
Brookes, A.22
Sanseau, P.23
Polinsky, R.J.24
Wasco, W.25
Silva, H.A.R.D.26
Haines, J.L.27
Pericak-Vance, M.A.28
Tanzi, R.E.29
Roses, A.D.30
Fraser, P.E.31
Romens, J.M.32
George-Hyslop, P.H.S.33
more..
-
56
-
-
0025785489
-
2+ channels are generated by alternative splicing and are differentially expressed in the mammalian CNS
-
2+ channels are generated by alternative splicing and are differentially expressed in the mammalian CNS. Neuron 7: 45-57, 1991.
-
(1991)
Neuron
, vol.7
, pp. 45-57
-
-
Snutch, T.P.1
Tomlinson, W.J.2
Leonard, J.P.3
Gilbert, M.M.4
-
58
-
-
0033535508
-
Presenilin is required for activity and nuclear access of Notch in Drosophila
-
Struhl G and Greenwald I. Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398: 522-525, 1999.
-
(1999)
Nature
, vol.398
, pp. 522-525
-
-
Struhl, G.1
Greenwald, I.2
-
60
-
-
0026472487
-
Dopamine receptor subtypes co-localize in rat striatonigral neurons
-
Surmeier DJ, Eberwine J, Wilson CJ, Stefani A, and Kitai ST. Dopamine receptor subtypes co-localize in rat striatonigral neurons. Proc Natl Acad Sci USA 89: 10178-10182, 1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10178-10182
-
-
Surmeier, D.J.1
Eberwine, J.2
Wilson, C.J.3
Stefani, A.4
Kitai, S.T.5
-
62
-
-
0028175280
-
2+ channel activity by deletions at the carboxyl terminus of the cardiac α1 subunit
-
2+ channel activity by deletions at the carboxyl terminus of the cardiac α1 subunit. J Biol Chem 269: 1635-1640, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 1635-1640
-
-
Wei, X.1
Neely, A.2
Lacerda, A.E.3
Olcese, R.4
Stefani, E.5
Perez-Reyes, E.6
Birnbaumer, L.7
-
63
-
-
0035168209
-
Gamma-secretase inhibitors as molecular probes of presenilin function
-
Wolfe MS. Gamma-secretase inhibitors as molecular probes of presenilin function. J Mol Neurosci 17: 199-204, 2001.
-
(2001)
J Mol Neurosci
, vol.17
, pp. 199-204
-
-
Wolfe, M.S.1
-
65
-
-
20744454142
-
β-subunits of voltage-gated sodium channels are novel substrates of β-site amyloid precursor protein - Cleaving enzyme (BACE1) and γ-secretase
-
Wong H-K, Sakurai T, Oyama F, Kaneko K, Wada K, Miyazaki H, Kurosawa M, De Strooper B, Saftig P, and Nukina N. β-subunits of voltage-gated sodium channels are novel substrates of β-site amyloid precursor protein - cleaving enzyme (BACE1) and γ-secretase. J Biol Chem 280: 23009-23017, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 23009-23017
-
-
Wong, H.-K.1
Sakurai, T.2
Oyama, F.3
Kaneko, K.4
Wada, K.5
Miyazaki, H.6
Kurosawa, M.7
De Strooper, B.8
Saftig, P.9
Nukina, N.10
-
66
-
-
1342321880
-
Presenilin-1 deficiency impairs glutamate-evoked intracellular calcium responses in neurons
-
Yang Y and Cook DG. Presenilin-1 deficiency impairs glutamate-evoked intracellular calcium responses in neurons. Neuroscience 124: 501-505, 2004.
-
(2004)
Neuroscience
, vol.124
, pp. 501-505
-
-
Yang, Y.1
Cook, D.G.2
-
67
-
-
0033712477
-
Presenilin-mediated modulation of capacitative calcium entry
-
Yoo AS, Cheng I, Chung S, Grenfell TZ, Lee H, Pack-Chung E, Handler M, Shen J, Xiz W, Tesco G, Saunders AJ, Ding K, Frosch MP, Tanzi RE, and Kim, T.-W. Presenilin-mediated modulation of capacitative calcium entry. Neuron 27: 561-572, 2000.
-
(2000)
Neuron
, vol.27
, pp. 561-572
-
-
Yoo, A.S.1
Cheng, I.2
Chung, S.3
Grenfell, T.Z.4
Lee, H.5
Pack-Chung, E.6
Handler, M.7
Shen, J.8
Xiz, W.9
Tesco, G.10
Saunders, A.J.11
Ding, K.12
Frosch, M.P.13
Tanzi, R.E.14
Kim, T.-W.15
-
68
-
-
0027433999
-
2+ channels and their possible counterparts in mammalian CNS neurons
-
2+ channels and their possible counterparts in mammalian CNS neurons. Neuropharmacology 32: 1075-1088, 1993.
-
(1993)
Neuropharmacology
, vol.32
, pp. 1075-1088
-
-
Zhang, J.-F.1
Randall, A.D.2
Ellinor, P.T.3
Horne, W.A.4
Sather, W.A.5
Tanabe, T.6
Schwartz, T.L.7
Tsien, R.W.8
|