-
1
-
-
4844220794
-
Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro
-
M.R. Abedini, Q. Qiu, X. Yan, and B.K. Tsang Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro Oncogene 23 2004 6997 7004
-
(2004)
Oncogene
, vol.23
, pp. 6997-7004
-
-
Abedini, M.R.1
Qiu, Q.2
Yan, X.3
Tsang, B.K.4
-
2
-
-
16844384891
-
Inhibition of HER-2 by three independent targeting strategies increases paclitaxel resistance of SKOV-3 ovarian carcinoma cells
-
S. Abuharbeid, J. Apel, G. Zugmaier, C. Knabbe, M. Sander, S. Gilbert, F. Czubayko, and A. Aigner Inhibition of HER-2 by three independent targeting strategies increases paclitaxel resistance of SKOV-3 ovarian carcinoma cells Naunyn Schmied. Arch. Pharmacol. 371 2005 141 151
-
(2005)
Naunyn Schmied. Arch. Pharmacol.
, vol.371
, pp. 141-151
-
-
Abuharbeid, S.1
Apel, J.2
Zugmaier, G.3
Knabbe, C.4
Sander, M.5
Gilbert, S.6
Czubayko, F.7
Aigner, A.8
-
3
-
-
0043240182
-
Ovarian cancer: Strategies for overcoming resistance to chemotherapy
-
R. Agarwal, and S.B. Kaye Ovarian cancer: strategies for overcoming resistance to chemotherapy Nat. Cancer Rev. 3 2003 502 516
-
(2003)
Nat. Cancer Rev.
, vol.3
, pp. 502-516
-
-
Agarwal, R.1
Kaye, S.B.2
-
4
-
-
4143111260
-
Akt and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor growth
-
D.A. Altomare, H.Q. Wang, K.L. Skele, A. De Rienzo, A.J. Klein-Szanto, A.K. Godwin, and J.R. Testa Akt and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor growth Oncogene 23 2004 5853 5857
-
(2004)
Oncogene
, vol.23
, pp. 5853-5857
-
-
Altomare, D.A.1
Wang, H.Q.2
Skele, K.L.3
De Rienzo, A.4
Klein-Szanto, A.J.5
Godwin, A.K.6
Testa, J.R.7
-
5
-
-
3242806803
-
Cisplatin activates survival signals in UM-SCC-23 squamous cell carcinoma and these signal pathways are amplified in cisplatin-resistant squamous cell carcinoma
-
K. Aoki, T. Ogawa, Y. Ito, and S. Nakashima Cisplatin activates survival signals in UM-SCC-23 squamous cell carcinoma and these signal pathways are amplified in cisplatin-resistant squamous cell carcinoma Oncol. Rep. 11 2004 375 379
-
(2004)
Oncol. Rep.
, vol.11
, pp. 375-379
-
-
Aoki, K.1
Ogawa, T.2
Ito, Y.3
Nakashima, S.4
-
6
-
-
0035266318
-
XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells
-
E. Asselin, G.B. Mills, and B.K. Tsang XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells Cancer Res. 61 2001 1862 1868
-
(2001)
Cancer Res.
, vol.61
, pp. 1862-1868
-
-
Asselin, E.1
Mills, G.B.2
Tsang, B.K.3
-
7
-
-
8544284078
-
The epigenetics of ovarian cancer drug resistance and resensitization
-
C. Balch, T.H. Huang, R. Brown, and K.P. Nephew The epigenetics of ovarian cancer drug resistance and resensitization Am. J. Obstet. Gynecol. 191 2004 1552 1572
-
(2004)
Am. J. Obstet. Gynecol.
, vol.191
, pp. 1552-1572
-
-
Balch, C.1
Huang, T.H.2
Brown, R.3
Nephew, K.P.4
-
8
-
-
0029127042
-
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
-
A. Bellacosa, D. DeFeo, A.K. Godwin, D.W. Bell, J.Q. Cheng, and D.A. Altomare Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas Int. J. Cancer 64 1995 280 285
-
(1995)
Int. J. Cancer
, vol.64
, pp. 280-285
-
-
Bellacosa, A.1
Defeo, D.2
Godwin, A.K.3
Bell, D.W.4
Cheng, J.Q.5
Altomare, D.A.6
-
9
-
-
21044455139
-
Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers
-
A. Berchuck, E.S. Iversen, J.M. Lancaster, J. Pittman, J. Luo, P. Lee, S. Murphy, H.K. Dressman, P.G. Febbo, M. West, J.R. Nevins, and J.R. Marks Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers Clin. Cancer Res. 11 2005 3686 3696
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 3686-3696
-
-
Berchuck, A.1
Iversen, E.S.2
Lancaster, J.M.3
Pittman, J.4
Luo, J.5
Lee, P.6
Murphy, S.7
Dressman, H.K.8
Febbo, P.G.9
West, M.10
Nevins, J.R.11
Marks, J.R.12
-
10
-
-
85047697328
-
Adenoviral delivery of A-FOS, an AP-1 dominant negative, selectively inhibits drug resistance in two human cancer cell lines
-
M. Bonovich, M. Olive, E. Reed, B. O'Connell, and C. Vinson Adenoviral delivery of A-FOS, an AP-1 dominant negative, selectively inhibits drug resistance in two human cancer cell lines Cancer Gene Ther. 9 2002 62 70
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 62-70
-
-
Bonovich, M.1
Olive, M.2
Reed, E.3
O'Connell, B.4
Vinson, C.5
-
11
-
-
24644443129
-
Modifications of DNA by platinum complexes: Relation to resistance of tumors to platinum antitumor drugs
-
V. Brabec, and J. Kasparkova Modifications of DNA by platinum complexes: relation to resistance of tumors to platinum antitumor drugs Drug Resist. Update 8 2005 131 146
-
(2005)
Drug Resist. Update
, vol.8
, pp. 131-146
-
-
Brabec, V.1
Kasparkova, J.2
-
12
-
-
8644269825
-
Long-term activation of SAPK/JNK, p38 kinase and fas-L expression by cisplatin is attenuated in human carcinoma cells that acquired drug resistance
-
A. Brozovic, G. Fritz, M. Christmann, J. Zisowsky, U. Jaehde, M. Osmak, and B. Kaina Long-term activation of SAPK/JNK, p38 kinase and fas-L expression by cisplatin is attenuated in human carcinoma cells that acquired drug resistance Int. J. Cancer 112 2004 974 985
-
(2004)
Int. J. Cancer
, vol.112
, pp. 974-985
-
-
Brozovic, A.1
Fritz, G.2
Christmann, M.3
Zisowsky, J.4
Jaehde, U.5
Osmak, M.6
Kaina, B.7
-
13
-
-
20244368055
-
Suppression of ovarian cancer cell tumorigenicity and evasion of cisplatin resistance using a truncated epidermal growth factor receptor in a rat model
-
J.K. Chan, H. Pham, X.J. You, N.G. Cloven, R.A. Burger, G.S. Rose, K. Van Nostrand, M. Korc, P.J. Disaia, and H. Fan Suppression of ovarian cancer cell tumorigenicity and evasion of cisplatin resistance using a truncated epidermal growth factor receptor in a rat model Cancer Res. 65 2005 3243 3248
-
(2005)
Cancer Res.
, vol.65
, pp. 3243-3248
-
-
Chan, J.K.1
Pham, H.2
You, X.J.3
Cloven, N.G.4
Burger, R.A.5
Rose, G.S.6
Van Nostrand, K.7
Korc, M.8
Disaia, P.J.9
Fan, H.10
-
14
-
-
14844333242
-
Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspase-9-independent activation of caspase-3
-
T. Chen, Y. Pengetnze, and C.C. Taylor Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspase-9-independent activation of caspase-3 Mol. Cancer Ther. 4 2005 217 224
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 217-224
-
-
Chen, T.1
Pengetnze, Y.2
Taylor, C.C.3
-
15
-
-
15544379141
-
Overexpression of dihydrodiol dehydrogenase is associated with cisplatin-based chemotherapy resistance in ovarian cancer patients
-
Y.J. Chen, C.C. Yuan, K.C. Chow, P.H. Wang, C.R. Lai, M.S. Yen, and L.S. Wang Overexpression of dihydrodiol dehydrogenase is associated with cisplatin-based chemotherapy resistance in ovarian cancer patients Gynecol. Oncol. 97 2005 110 117
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 110-117
-
-
Chen, Y.J.1
Yuan, C.C.2
Chow, K.C.3
Wang, P.H.4
Lai, C.R.5
Yen, M.S.6
Wang, L.S.7
-
16
-
-
0036619301
-
Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: Possible involvement of the phosphoinositide-3 kinase /Akt pathway
-
J.Q. Cheng, X. Jiang, M. Fraser, M. Li, H.C. Dan, M. Sun, and B.K. Tsang Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase /Akt pathway Drug Resist. Update 5 2002 131 146
-
(2002)
Drug Resist. Update
, vol.5
, pp. 131-146
-
-
Cheng, J.Q.1
Jiang, X.2
Fraser, M.3
Li, M.4
Dan, H.C.5
Sun, M.6
Tsang, B.K.7
-
17
-
-
15244345318
-
Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP
-
J. Cummings, T.H. Ward, E. LaCasse, C. Lefebvre, M. St-Jean, J. Durkin, M. Ranson, and C. Dive Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP Br. J. Cancer 92 2005 532 538
-
(2005)
Br. J. Cancer
, vol.92
, pp. 532-538
-
-
Cummings, J.1
Ward, T.H.2
Lacasse, E.3
Lefebvre, C.4
St-Jean, M.5
Durkin, J.6
Ranson, M.7
Dive, C.8
-
18
-
-
0034985464
-
Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells
-
M. Cuello, S.A. Ettenberg, M.M. Nau, and S. Lipkowitz Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells Gynecol. Oncol. 81 2001 380 390
-
(2001)
Gynecol. Oncol.
, vol.81
, pp. 380-390
-
-
Cuello, M.1
Ettenberg, S.A.2
Nau, M.M.3
Lipkowitz, S.4
-
19
-
-
2342596529
-
The Fanconi anemia/BRCA signaling pathway: Disruption in cisplatin-sensitive ovarian cancers
-
A.D. D'Andrea The Fanconi anemia/BRCA signaling pathway: disruption in cisplatin-sensitive ovarian cancers Cell Cycle 2 2003 290 292
-
(2003)
Cell Cycle
, vol.2
, pp. 290-292
-
-
D'Andrea, A.D.1
-
20
-
-
16544395591
-
DNA methylation and cancer
-
P.M. Das, and R. Singal DNA methylation and cancer J. Clin. Oncol. 22 2004 4632 4642
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 4632-4642
-
-
Das, P.M.1
Singal, R.2
-
21
-
-
0036176126
-
Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: Requirement for Akt activation
-
D. Del Bufalo, V. Di Castro, A. Biroccio, M. Varmi, D. Salani, L. Rosano, D. Trisciuoglio, F. Spinella, and A. Bagnato Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation Mol. Pharmacol. 61 2002 524 532
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 524-532
-
-
Del Bufalo, D.1
Di Castro, V.2
Biroccio, A.3
Varmi, M.4
Salani, D.5
Rosano, L.6
Trisciuoglio, D.7
Spinella, F.8
Bagnato, A.9
-
22
-
-
4644249735
-
Ubiquitous induction of resistance to platinum drugs in human ovarian, cervical, germ-cell and lung carcinoma tumor cells overexpressing isoforms 1 and 2 of dihydrodiol dehydrogenase
-
H.B. Deng, M. Adikari, H.K. Parekh, and H. Simpkins Ubiquitous induction of resistance to platinum drugs in human ovarian, cervical, germ-cell and lung carcinoma tumor cells overexpressing isoforms 1 and 2 of dihydrodiol dehydrogenase Cancer Chemother. Pharmacol. 54 2004 301 307
-
(2004)
Cancer Chemother. Pharmacol.
, vol.54
, pp. 301-307
-
-
Deng, H.B.1
Adikari, M.2
Parekh, H.K.3
Simpkins, H.4
-
23
-
-
0037177887
-
Increased expression of dihydrodiol dehydrogenase induces resistance to cisplatin in human ovarian carcinoma cells
-
H.B. Deng, H.K. Parekh, K.C. Chow, and H. Simpkins Increased expression of dihydrodiol dehydrogenase induces resistance to cisplatin in human ovarian carcinoma cells J. Biol. Chem. 277 2002 15035 15043
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15035-15043
-
-
Deng, H.B.1
Parekh, H.K.2
Chow, K.C.3
Simpkins, H.4
-
24
-
-
11244316378
-
Early phase I data on an irreversible pan-erb inhibitor: CI-1033. What did we learn?
-
M.R. Dewji Early phase I data on an irreversible pan-erb inhibitor: CI-1033. What did we learn? J. Chemother. 16 Suppl. 4 2004 44 48
-
(2004)
J. Chemother.
, vol.16
, Issue.4 SUPPL.
, pp. 44-48
-
-
Dewji, M.R.1
-
25
-
-
4444275386
-
Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells
-
Z. Duan, K.A. Brakora, and M.V. Seiden Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells Mol. Cancer Ther. 3 2004 833 838
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 833-838
-
-
Duan, Z.1
Brakora, K.A.2
Seiden, M.V.3
-
26
-
-
0037625216
-
Overexpression of MAGE/GAGE genes in paclitaxel/doxorubicin-resistant human cancer cell lines
-
Z. Duan, Y. Duan, D.E. Lamendola, R.Z. Yusuf, R. Naeem, R.T. Penson, and M.V. Seiden Overexpression of MAGE/GAGE genes in paclitaxel/doxorubicin- resistant human cancer cell lines Clin. Cancer Res. 9 2003 2778 2785
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 2778-2785
-
-
Duan, Z.1
Duan, Y.2
Lamendola, D.E.3
Yusuf, R.Z.4
Naeem, R.5
Penson, R.T.6
Seiden, M.V.7
-
27
-
-
12444303179
-
Description of paclitaxel resistance-associated genes in ovarian and breast cancer cell lines
-
Z. Duan, D.E. Lamendola, Y. Duan, R.Z. Yusuf, and M.V. Seiden Description of paclitaxel resistance-associated genes in ovarian and breast cancer cell lines Cancer Chemother. Pharmacol. 55 2005 277 285
-
(2005)
Cancer Chemother. Pharmacol.
, vol.55
, pp. 277-285
-
-
Duan, Z.1
Lamendola, D.E.2
Duan, Y.3
Yusuf, R.Z.4
Seiden, M.V.5
-
28
-
-
15344344553
-
Imatinib mesylate and its potential implications for gynecologic cancers
-
H. Dushkin, and R.J. Schilder Imatinib mesylate and its potential implications for gynecologic cancers Curr. Treat. Options Oncol. 6 2005 115 120
-
(2005)
Curr. Treat. Options Oncol.
, vol.6
, pp. 115-120
-
-
Dushkin, H.1
Schilder, R.J.2
-
29
-
-
20444502625
-
Trastuzumab: Targeted therapy for the management of HER-2/neu- overexpressing metastatic breast cancer
-
L.A. Emens Trastuzumab: targeted therapy for the management of HER-2/neu-overexpressing metastatic breast cancer Am. J. Ther. 12 2005 243 253
-
(2005)
Am. J. Ther.
, vol.12
, pp. 243-253
-
-
Emens, L.A.1
-
30
-
-
1842609941
-
Inhibition of AKT abrogates chemotherapy-induced NF-kappaB survival mechanisms: Implications for therapy in pancreatic cancer
-
B.N. Fahy, M.G. Schlieman, S. Virudachalam, and R.J. Bold Inhibition of AKT abrogates chemotherapy-induced NF-kappaB survival mechanisms: implications for therapy in pancreatic cancer J. Am. Coll. Surg. 198 2004 591 599
-
(2004)
J. Am. Coll. Surg.
, vol.198
, pp. 591-599
-
-
Fahy, B.N.1
Schlieman, M.G.2
Virudachalam, S.3
Bold, R.J.4
-
31
-
-
0242610903
-
P53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells
-
M. Fraser, B.M. Leung, X. Yan, H.C. Dan, J.Q. Cheng, and B.K. Tsang p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells Cancer Res. 63 2003 7081 7088
-
(2003)
Cancer Res.
, vol.63
, pp. 7081-7088
-
-
Fraser, M.1
Leung, B.M.2
Yan, X.3
Dan, H.C.4
Cheng, J.Q.5
Tsang, B.K.6
-
32
-
-
2442625248
-
Gene expression profiles in the cellular response to a multinuclear platinum complex
-
L. Gatti, G.L. Beretta, N. Carenini, E. Corna, F. Zunino, and P. Perego Gene expression profiles in the cellular response to a multinuclear platinum complex Cell. Mol. Life Sci. 61 2004 973 981
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 973-981
-
-
Gatti, L.1
Beretta, G.L.2
Carenini, N.3
Corna, E.4
Zunino, F.5
Perego, P.6
-
33
-
-
24944458177
-
Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: Induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death
-
G.V. Georgakis, Y. Li, R. Humphreys, M. Andreeff, S. O'Brien, M. Younes, A. Carbone, V. Albert, and A. Younes Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death Br. J. Haematol. 130 2005 501 510
-
(2005)
Br. J. Haematol.
, vol.130
, pp. 501-510
-
-
Georgakis, G.V.1
Li, Y.2
Humphreys, R.3
Andreeff, M.4
O'Brien, S.5
Younes, M.6
Carbone, A.7
Albert, V.8
Younes, A.9
-
34
-
-
3042774430
-
The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients
-
G. Gifford, J. Paul, P.A. Vasey, S.B. Kaye, and R. Brown The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients Clin. Cancer Res. 10 2004 4420 4426
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4420-4426
-
-
Gifford, G.1
Paul, J.2
Vasey, P.A.3
Kaye, S.B.4
Brown, R.5
-
35
-
-
0036748447
-
Significance of nuclear glutathione S-transferase pi in resistance to anti-cancer drugs
-
S. Goto, K. Kamada, Y. Soh, Y. Ihara, and T. Kondo Significance of nuclear glutathione S-transferase pi in resistance to anti-cancer drugs Jpn. J. Cancer Res. 93 2002 1047 1056
-
(2002)
Jpn. J. Cancer Res.
, vol.93
, pp. 1047-1056
-
-
Goto, S.1
Kamada, K.2
Soh, Y.3
Ihara, Y.4
Kondo, T.5
-
36
-
-
3042570458
-
Oblimersen sodium (Genasense bcl-2 antisense oligonucleotide): A rational therapeutic to enhance apoptosis in therapy of lung cancer
-
R.S. Herbst, and S.R. Frankel Oblimersen sodium (Genasense bcl-2 antisense oligonucleotide): a rational therapeutic to enhance apoptosis in therapy of lung cancer Clin. Cancer Res. 10 2004 4245s 4248s
-
(2004)
Clin. Cancer Res.
, vol.10
-
-
Herbst, R.S.1
Frankel, S.R.2
-
37
-
-
0037112433
-
Resistance to chemotherapy mediated by TrkB in neuroblastomas
-
R. Ho, A. Eggert, T. Hishiki, J.E. Minturn, N. Ikegaki, P. Foster, A.M. Camoratto, A.E. Evans, and G.M. Brodeur Resistance to chemotherapy mediated by TrkB in neuroblastomas Cancer Res. 62 2002 6462 6466
-
(2002)
Cancer Res.
, vol.62
, pp. 6462-6466
-
-
Ho, R.1
Eggert, A.2
Hishiki, T.3
Minturn, J.E.4
Ikegaki, N.5
Foster, P.6
Camoratto, A.M.7
Evans, A.E.8
Brodeur, G.M.9
-
38
-
-
4844228226
-
The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells
-
A.K. Holzer, G. Samimi, K. Katano, W. Naerdemann, X. Lin, R. Safaei, and S.B. Howell The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells Mol. Pharmacol. 66 2004 817 823
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 817-823
-
-
Holzer, A.K.1
Samimi, G.2
Katano, K.3
Naerdemann, W.4
Lin, X.5
Safaei, R.6
Howell, S.B.7
-
39
-
-
0036168948
-
Inhibition of phosphatidylinositol 3′-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models
-
L. Hu, J. Hofmann, Y. Lu, G.B. Mills, and R.B. Jaffe Inhibition of phosphatidylinositol 3′-kinase increases efficacy of paclitaxel in in vitro and in vivo ovarian cancer models Cancer Res. 62 2002 1087 1092
-
(2002)
Cancer Res.
, vol.62
, pp. 1087-1092
-
-
Hu, L.1
Hofmann, J.2
Lu, Y.3
Mills, G.B.4
Jaffe, R.B.5
-
40
-
-
1842555274
-
Subcellular targeting regulates the function of caspase-activated protein kinases in apoptosis
-
R. Jakobi Subcellular targeting regulates the function of caspase-activated protein kinases in apoptosis Drug Resist. Update 7 2004 11 17
-
(2004)
Drug Resist. Update
, vol.7
, pp. 11-17
-
-
Jakobi, R.1
-
41
-
-
21244445833
-
Atrasentan: A novel and rationally designed therapeutic alternative in the management of cancer
-
A. Jimeno, and M. Carducci Atrasentan: a novel and rationally designed therapeutic alternative in the management of cancer Expert Rev. Anticancer Ther. 5 2005 419 427
-
(2005)
Expert Rev. Anticancer Ther.
, vol.5
, pp. 419-427
-
-
Jimeno, A.1
Carducci, M.2
-
42
-
-
16844365749
-
{Beta}III-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability
-
K. Kamath, L. Wilson, F. Cabral, and M.A. Jordan {Beta}III-tubulin induces paclitaxel resistance in association with reduced effects on microtubule dynamic instability J. Biol. Chem. 280 2005 12902 12907
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12902-12907
-
-
Kamath, K.1
Wilson, L.2
Cabral, F.3
Jordan, M.A.4
-
43
-
-
0037854571
-
Phenoxodiol - An isoflavone analog - Induces apoptosis in chemoresistant ovarian cancer cells
-
M. Kamsteeg, T. Rutherford, E. Sapi, B. Hanczaruk, S. Shahabi, M. Flick, D. Brown, and G. Mor Phenoxodiol - an isoflavone analog - induces apoptosis in chemoresistant ovarian cancer cells Oncogene 22 2003 2611 2620
-
(2003)
Oncogene
, vol.22
, pp. 2611-2620
-
-
Kamsteeg, M.1
Rutherford, T.2
Sapi, E.3
Hanczaruk, B.4
Shahabi, S.5
Flick, M.6
Brown, D.7
Mor, G.8
-
44
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
M. Karin, and A. Lin NF-kappaB at the crossroads of life and death Nat. Immunol. 3 2002 221 227
-
(2002)
Nat. Immunol.
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
45
-
-
0037112421
-
Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper
-
K. Katano, A. Kondo, R. Safaei, A. Holzer, G. Samimi, M. Mishima, Y.M. Kuo, M. Rochdi, and S.B. Howell Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper Cancer Res. 62 2002 6559 6565
-
(2002)
Cancer Res.
, vol.62
, pp. 6559-6565
-
-
Katano, K.1
Kondo, A.2
Safaei, R.3
Holzer, A.4
Samimi, G.5
Mishima, M.6
Kuo, Y.M.7
Rochdi, M.8
Howell, S.B.9
-
46
-
-
0041341920
-
The copper export pump ATP7B modulates the cellular pharmacology of carboplatin in ovarian carcinoma cells
-
K. Katano, R. Safaei, G. Samimi, A. Holzer, M. Rochdi, and S.B. Howell The copper export pump ATP7B modulates the cellular pharmacology of carboplatin in ovarian carcinoma cells Mol. Pharmacol. 64 2003 466 473
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 466-473
-
-
Katano, K.1
Safaei, R.2
Samimi, G.3
Holzer, A.4
Rochdi, M.5
Howell, S.B.6
-
47
-
-
3042815040
-
Confocal microscopic analysis of the interaction between cisplatin and the copper transporter ATP7B in human ovarian carcinoma cells
-
K. Katano, R. Safaei, G. Samimi, A. Holzer, M. Tomioka, M. Goodman, and S.B. Howell Confocal microscopic analysis of the interaction between cisplatin and the copper transporter ATP7B in human ovarian carcinoma cells Clin. Cancer Res. 10 2004 4578 4588
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4578-4588
-
-
Katano, K.1
Safaei, R.2
Samimi, G.3
Holzer, A.4
Tomioka, M.5
Goodman, M.6
Howell, S.B.7
-
48
-
-
9744263911
-
The role of BRCA1 in the cellular response to chemotherapy
-
R.D. Kennedy, J.E. Quinn, P.B. Mullan, P.G. Johnston, and D.P. Harkin The role of BRCA1 in the cellular response to chemotherapy J. Natl. Cancer Inst. 96 2004 1659 1668
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 1659-1668
-
-
Kennedy, R.D.1
Quinn, J.E.2
Mullan, P.B.3
Johnston, P.G.4
Harkin, D.P.5
-
49
-
-
27144451832
-
Effective combinations of carboplatin with low doses of TRAIL, HGS-ETR1 and HGS-ETR2 in the TRAIL-sensitive HX62 human ovarian tumour cell line
-
B. Krishan, M.G. Ormerod, S.B. Kaye, and A.L. Jackman Effective combinations of carboplatin with low doses of TRAIL, HGS-ETR1 and HGS-ETR2 in the TRAIL-sensitive HX62 human ovarian tumour cell line Eur. J. Cancer Suppl. 2 2004 19
-
(2004)
Eur. J. Cancer Suppl.
, vol.2
, pp. 19
-
-
Krishan, B.1
Ormerod, M.G.2
Kaye, S.B.3
Jackman, A.L.4
-
50
-
-
0034976644
-
Frequent loss of PTEN expression in linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas
-
K. Kurose, X.P. Zhou, T. Araki, S.A. Cannistra, E.R. Maher, and C. Eng Frequent loss of PTEN expression in linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas Am. J. Pathol. 158 2001 2097 2106
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 2097-2106
-
-
Kurose, K.1
Zhou, X.P.2
Araki, T.3
Cannistra, S.A.4
Maher, E.R.5
Eng, C.6
-
51
-
-
10644256805
-
A phase I trial of the DNA-hypomethylating agent 5-aza-2′- deoxycytidine in combination with carboplatin both given 4 weekly by intravenous injection in patients with advanced solid tumours
-
C. Lee, K. Appleton, J.A. Plumb, S.B. Kaye, C. Cruickshank, P. Twelves, P.A. Vasey, I. Judson, R. Brown, and H. Mackay A phase I trial of the DNA-hypomethylating agent 5-aza-2′-deoxycytidine in combination with carboplatin both given 4 weekly by intravenous injection in patients with advanced solid tumours Proc. Am. Soc. Clin. Oncol. 23 2004 128
-
(2004)
Proc. Am. Soc. Clin. Oncol.
, vol.23
, pp. 128
-
-
Lee, C.1
Appleton, K.2
Plumb, J.A.3
Kaye, S.B.4
Cruickshank, C.5
Twelves, P.6
Vasey, P.A.7
Judson, I.8
Brown, R.9
MacKay, H.10
-
52
-
-
8544230666
-
Phosphatidylinositol 3′-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells
-
J.T. Lee Jr., L.S. Steelman, and J.A. McCubrey Phosphatidylinositol 3′-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells Cancer Res. 64 2004 8397 8404
-
(2004)
Cancer Res.
, vol.64
, pp. 8397-8404
-
-
Lee Jr., J.T.1
Steelman, L.S.2
McCubrey, J.A.3
-
53
-
-
15544369937
-
Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line
-
S. Lee, E.J. Choi, C. Jin, and D.H. Kim Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line Gynecol. Oncol. 97 2005 26 34
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 26-34
-
-
Lee, S.1
Choi, E.J.2
Jin, C.3
Kim, D.H.4
-
54
-
-
17744379360
-
Human ovarian cancer and cisplatin resistance: Possible role of inhibitor of apoptosis proteins
-
J. Li, Q. Feng, J.M. Kim, D. Schneiderman, P. Liston, M. Li, B. Vanderhyden, W. Faught, M.F. Fung, M. Senterman, R.G. Korneluk, and B.K. Tsang Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins Endocrinology 142 2001 370 380
-
(2001)
Endocrinology
, vol.142
, pp. 370-380
-
-
Li, J.1
Feng, Q.2
Kim, J.M.3
Schneiderman, D.4
Liston, P.5
Li, M.6
Vanderhyden, B.7
Faught, W.8
Fung, M.F.9
Senterman, M.10
Korneluk, R.G.11
Tsang, B.K.12
-
55
-
-
0038482086
-
Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells
-
A. Mansouri, L.D. Ridgway, A.L. Korapati, Q. Zhang, L. Tian, Y. Wang, Z.H. Siddik, G.B. Mills, and F.X. Claret Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells J. Biol. Chem. 278 2003 19245 19256
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19245-19256
-
-
Mansouri, A.1
Ridgway, L.D.2
Korapati, A.L.3
Zhang, Q.4
Tian, L.5
Wang, Y.6
Siddik, Z.H.7
Mills, G.B.8
Claret, F.X.9
-
56
-
-
14844346661
-
Protection of platinum-DNA adduct formation and reversal of cisplatin resistance by anti-MRP2 hammerhead ribozymes in human cancer cells
-
V. Materna, B. Liedert, J. Thomale, and H. Lage Protection of platinum-DNA adduct formation and reversal of cisplatin resistance by anti-MRP2 hammerhead ribozymes in human cancer cells Int. J. Cancer 115 2005 393 402
-
(2005)
Int. J. Cancer
, vol.115
, pp. 393-402
-
-
Materna, V.1
Liedert, B.2
Thomale, J.3
Lage, H.4
-
57
-
-
21244493635
-
Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling
-
C.S. Mitsiades, and N. Mitsiades Treatment of hematologic malignancies and solid tumors by inhibiting IGF receptor signaling Expert Rev. Anticancer Ther. 5 2005 487 499
-
(2005)
Expert Rev. Anticancer Ther.
, vol.5
, pp. 487-499
-
-
Mitsiades, C.S.1
Mitsiades, N.2
-
58
-
-
0034625346
-
Expression of oncogenic epidermal growth factor receptor family kinases induces paclitaxel resistance and alters beta-tubulin isotype expression
-
R.B. Montgomery, J. Guzman, D.M. O'Rourke, and W.L. Stahl Expression of oncogenic epidermal growth factor receptor family kinases induces paclitaxel resistance and alters beta-tubulin isotype expression J. Biol. Chem. 275 2000 17358 17363
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17358-17363
-
-
Montgomery, R.B.1
Guzman, J.2
O'Rourke, D.M.3
Stahl, W.L.4
-
59
-
-
0141520276
-
Drug resistance and the microenvironment: Nature and nurture
-
P.J. Morin Drug resistance and the microenvironment: nature and nurture Drug Resist. Update 6 2003 169 172
-
(2003)
Drug Resist. Update
, vol.6
, pp. 169-172
-
-
Morin, P.J.1
-
60
-
-
19944430079
-
Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients
-
S. Mozzetti, C. Ferlini, P. Concolino, F. Filippetti, G. Raspaglio, S. Prislei, D. Gallo, E. Martinelli, F.O. Ranelletti, G. Ferrandina, and G. Scambia Class III beta-tubulin overexpression is a prominent mechanism of paclitaxel resistance in ovarian cancer patients Clin. Cancer Res. 11 2005 298 305
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 298-305
-
-
Mozzetti, S.1
Ferlini, C.2
Concolino, P.3
Filippetti, F.4
Raspaglio, G.5
Prislei, S.6
Gallo, D.7
Martinelli, E.8
Ranelletti, F.O.9
Ferrandina, G.10
Scambia, G.11
-
61
-
-
4544263294
-
Molecular mechanism of chemoresistance to cisplatin in ovarian cancer cell lines
-
T. Murata, M. Haisa, H. Uetsuka, T. Nobuhisa, T. Ookawa, Y. Tabuchi, Y. Shirakawa, T. Yamatsuji, J. Matsuoka, M. Nishiyama, N. Tanaka, and Y. Naomoto Molecular mechanism of chemoresistance to cisplatin in ovarian cancer cell lines Int. J. Mol. Med. 13 2004 865 868
-
(2004)
Int. J. Mol. Med.
, vol.13
, pp. 865-868
-
-
Murata, T.1
Haisa, M.2
Uetsuka, H.3
Nobuhisa, T.4
Ookawa, T.5
Tabuchi, Y.6
Shirakawa, Y.7
Yamatsuji, T.8
Matsuoka, J.9
Nishiyama, M.10
Tanaka, N.11
Naomoto, Y.12
-
62
-
-
11144354318
-
Prognostic value of the Cu-transporting ATPase in ovarian carcinoma patients receiving cisplatin-based chemotherapy
-
K. Nakayama, A. Kanzaki, K. Terada, M. Mutoh, K. Ogawa, T. Sugiyama, S. Takenoshita, K. Itoh, N. Yaegashi, K. Miyazaki, N. Neamati, and Y. Takebayashi Prognostic value of the Cu-transporting ATPase in ovarian carcinoma patients receiving cisplatin-based chemotherapy Clin. Cancer Res. 10 2004 2804 2811
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 2804-2811
-
-
Nakayama, K.1
Kanzaki, A.2
Terada, K.3
Mutoh, M.4
Ogawa, K.5
Sugiyama, T.6
Takenoshita, S.7
Itoh, K.8
Yaegashi, N.9
Miyazaki, K.10
Neamati, N.11
Takebayashi, Y.12
-
63
-
-
21144451094
-
In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
-
T. O'Hare, D.K. Walters, E.P. Stoffregen, T. Jia, P.W. Manley, J. Mestan, S.W. Cowan-Jacob, F.Y. Lee, M.C. Heinrich, M.W. Deininger, and B.J. Druker In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants Cancer Res. 65 2005 4500 4505
-
(2005)
Cancer Res.
, vol.65
, pp. 4500-4505
-
-
O'Hare, T.1
Walters, D.K.2
Stoffregen, E.P.3
Jia, T.4
Manley, P.W.5
Mestan, J.6
Cowan-Jacob, S.W.7
Lee, F.Y.8
Heinrich, M.C.9
Deininger, M.W.10
Druker, B.J.11
-
64
-
-
0037336279
-
Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and Bcl-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin
-
R.I. Pakunlu, T.J. Cook, and T. Minko Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and Bcl-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin Pharm. Res. 20 2003 351 359
-
(2003)
Pharm. Res.
, vol.20
, pp. 351-359
-
-
Pakunlu, R.I.1
Cook, T.J.2
Minko, T.3
-
65
-
-
0036569631
-
Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): Evidence for the role of transcription factor overexpression in determining resistant phenotype
-
B. Pan, K.S. Yao, B.P. Monia, N.M. Dean, R.A. McKay, T.C. Hamilton, and P.J. O'Dwyer Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistant phenotype Biochem. Pharmacol. 63 2002 1699 1707
-
(2002)
Biochem. Pharmacol.
, vol.63
, pp. 1699-1707
-
-
Pan, B.1
Yao, K.S.2
Monia, B.P.3
Dean, N.M.4
McKay, R.A.5
Hamilton, T.C.6
O'Dwyer, P.J.7
-
66
-
-
0041422435
-
Src tyrosine kinase promotes survival and resistance to chemotherapeutics in a mouse ovarian cancer cell line
-
Y. Pengetnze, M. Steed, K.F. Roby, P.F. Terranova, and C.C. Taylor Src tyrosine kinase promotes survival and resistance to chemotherapeutics in a mouse ovarian cancer cell line Biochem. Biophys. Res. Commun. 309 2003 377 383
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.309
, pp. 377-383
-
-
Pengetnze, Y.1
Steed, M.2
Roby, K.F.3
Terranova, P.F.4
Taylor, C.C.5
-
67
-
-
23844477497
-
Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930
-
F. Petti, A. Thelemann, J. Kahler, S. McCormack, L. Castaldo, T. Hunt, L. Nuwaysir, L. Zeiske, H. Haack, L. Sullivan, A. Garton, and J.D. Haley Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930 Mol. Cancer Ther. 4 2005 1186 1197
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1186-1197
-
-
Petti, F.1
Thelemann, A.2
Kahler, J.3
McCormack, S.4
Castaldo, L.5
Hunt, T.6
Nuwaysir, L.7
Zeiske, L.8
Haack, H.9
Sullivan, L.10
Garton, A.11
Haley, J.D.12
-
68
-
-
0842304432
-
Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src
-
P.A. Ple, T.P. Green, L.F. Hennequin, J. Curwen, M. Fennell, J. Allen, C. Lambert-Van Der Brempt, and G. Costello Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src J. Med. Chem. 47 2004 871 887
-
(2004)
J. Med. Chem.
, vol.47
, pp. 871-887
-
-
Ple, P.A.1
Green, T.P.2
Hennequin, L.F.3
Curwen, J.4
Fennell, M.5
Allen, J.6
Lambert-Van Der Brempt, C.7
Costello, G.8
-
69
-
-
2442464889
-
Apoptosis defects and chemotherapy resistance: Molecular interaction maps and networks
-
Y. Pommier, O. Sordet, S. Antony, R.L. Hayward, and K.W. Kohn Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks Oncogene 23 2004 2934 2949
-
(2004)
Oncogene
, vol.23
, pp. 2934-2949
-
-
Pommier, Y.1
Sordet, O.2
Antony, S.3
Hayward, R.L.4
Kohn, K.W.5
-
70
-
-
2342418119
-
C-KIT expression and correlation with chemotherapy resistance in ovarian carcinoma: An immunocytochemical study
-
M.R. Raspollini, G. Amunni, A. Villanucci, G. Baroni, A. Taddei, and G.L. Taddei c-KIT expression and correlation with chemotherapy resistance in ovarian carcinoma: an immunocytochemical study Ann. Oncol. 15 2004 594 597
-
(2004)
Ann. Oncol.
, vol.15
, pp. 594-597
-
-
Raspollini, M.R.1
Amunni, G.2
Villanucci, A.3
Baroni, G.4
Taddei, A.5
Taddei, G.L.6
-
71
-
-
17444362227
-
Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells
-
D. Roberts, J. Schick, S. Conway, S. Biade, P.B. Laub, J.P. Stevenson, T.C. Hamilton, J. O'Dwyer P, and S.W. Johnson Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells Br. J. Cancer 92 2005 1149 1158
-
(2005)
Br. J. Cancer
, vol.92
, pp. 1149-1158
-
-
Roberts, D.1
Schick, J.2
Conway, S.3
Biade, S.4
Laub, P.B.5
Stevenson, J.P.6
Hamilton, T.C.7
O'Dwyer, P.J.8
Johnson, S.W.9
-
72
-
-
27944480275
-
Combination of the Hsp90 inhibitor, 17-AAG, with taxol in human ovarian tumour cell lines
-
N. Sain, B. Krishnan, F. Yafai, M.G. Ormerod, S.B. Kaye, P. Workman, and A.L. Jackman Combination of the Hsp90 inhibitor, 17-AAG, with taxol in human ovarian tumour cell lines Proc. Am. Assoc. Cancer Res. 45 2004 458
-
(2004)
Proc. Am. Assoc. Cancer Res.
, vol.45
, pp. 458
-
-
Sain, N.1
Krishnan, B.2
Yafai, F.3
Ormerod, M.G.4
Kaye, S.B.5
Workman, P.6
Jackman, A.L.7
-
73
-
-
1542289967
-
Overexpression of MEKK3 confers resistance to apoptosis through activation of NFkappaB
-
A.K. Samanta, H.J. Huang, R.C. Bast Jr., and W.S. Liao Overexpression of MEKK3 confers resistance to apoptosis through activation of NFkappaB J. Biol. Chem. 279 2004 7576 7583
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7576-7583
-
-
Samanta, A.K.1
Huang, H.J.2
Bast Jr., R.C.3
Liao, W.S.4
-
74
-
-
11244336630
-
CDNA microarray-based identification of genes and pathways associated with oxaliplatin resistance
-
G. Samimi, G. Manorek, R. Castel, J.K. Breaux, T.C. Cheng, C.C. Berry, G. Los, and S.B. Howell cDNA microarray-based identification of genes and pathways associated with oxaliplatin resistance Cancer Chemother. Pharmacol. 55 2005 1 11
-
(2005)
Cancer Chemother. Pharmacol.
, vol.55
, pp. 1-11
-
-
Samimi, G.1
Manorek, G.2
Castel, R.3
Breaux, J.K.4
Cheng, T.C.5
Berry, C.C.6
Los, G.7
Howell, S.B.8
-
75
-
-
3242734736
-
Increased expression of the copper efflux transporter ATP7A mediates resistance to cisplatin, carboplatin, and oxaliplatin in ovarian cancer cells
-
G. Samimi, R. Safaei, K. Katano, A.K. Holzer, M. Rochdi, M. Tomioka, M. Goodman, and S.B. Howell Increased expression of the copper efflux transporter ATP7A mediates resistance to cisplatin, carboplatin, and oxaliplatin in ovarian cancer cells Clin. Cancer Res. 10 2004 4661 4669
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4661-4669
-
-
Samimi, G.1
Safaei, R.2
Katano, K.3
Holzer, A.K.4
Rochdi, M.5
Tomioka, M.6
Goodman, M.7
Howell, S.B.8
-
76
-
-
0037353562
-
Time to progression is dependent on the expression of the tumour suppressor PTEN in ovarian cancer patients
-
T. Schondorf, U.J. Gohring, G. Roth, I. Middel, M. Becker, N. Moser, M.M. Valter, and M. Hoopmann Time to progression is dependent on the expression of the tumour suppressor PTEN in ovarian cancer patients Eur. J. Clin. Invest. 33 2003 256 260
-
(2003)
Eur. J. Clin. Invest.
, vol.33
, pp. 256-260
-
-
Schondorf, T.1
Gohring, U.J.2
Roth, G.3
Middel, I.4
Becker, M.5
Moser, N.6
Valter, M.M.7
Hoopmann, M.8
-
77
-
-
0037444279
-
Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines
-
M. Selvakumaran, D.A. Pisarcik, R. Bao, A.T. Yeung, and T.C. Hamilton Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines Cancer Res. 63 2003 1311 1316
-
(2003)
Cancer Res.
, vol.63
, pp. 1311-1316
-
-
Selvakumaran, M.1
Pisarcik, D.A.2
Bao, R.3
Yeung, A.T.4
Hamilton, T.C.5
-
78
-
-
4644243615
-
Prediction of chemotherapeutic response in ovarian cancer with DNA microarray expression profiling
-
Z.E. Selvanayagam, T.H. Cheung, N. Wei, R. Vittal, K.W. Lo, W. Yeo, T. Kita, R. Ravatn, T.K. Chung, Y.F. Wong, and K.V. Chin Prediction of chemotherapeutic response in ovarian cancer with DNA microarray expression profiling Cancer Genet. Cytogenet. 154 2004 63 66
-
(2004)
Cancer Genet. Cytogenet.
, vol.154
, pp. 63-66
-
-
Selvanayagam, Z.E.1
Cheung, T.H.2
Wei, N.3
Vittal, R.4
Lo, K.W.5
Yeo, W.6
Kita, T.7
Ravatn, R.8
Chung, T.K.9
Wong, Y.F.10
Chin, K.V.11
-
79
-
-
0032590011
-
PIK3CA is implicated as an oncogene in ovarian cancer
-
L. Shayesteh, Y. Lu, W.L. Kuo, R. Baldocchi, T. Godfrey, C. Collins, D. Pinkel, B. Powell, G.B. Mills, and J.W. Gray PIK3CA is implicated as an oncogene in ovarian cancer Nat Genet. 21 1999 99 102
-
(1999)
Nat Genet.
, vol.21
, pp. 99-102
-
-
Shayesteh, L.1
Lu, Y.2
Kuo, W.L.3
Baldocchi, R.4
Godfrey, T.5
Collins, C.6
Pinkel, D.7
Powell, B.8
Mills, G.B.9
Gray, J.W.10
-
80
-
-
0141484480
-
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells
-
C.A. Sherman-Baust, A.T. Weeraratna, L.B. Rangel, E.S. Pizer, K.R. Cho, D.R. Schwartz, T. Shock, and P.J. Morin Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells Cancer Cell 3 2003 377 386
-
(2003)
Cancer Cell
, vol.3
, pp. 377-386
-
-
Sherman-Baust, C.A.1
Weeraratna, A.T.2
Rangel, L.B.3
Pizer, E.S.4
Cho, K.R.5
Schwartz, D.R.6
Shock, T.7
Morin, P.J.8
-
81
-
-
0035872480
-
Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer
-
V. Shridhar, K.C. Bible, J. Staub, R. Avula, Y.K. Lee, K. Kalli, H. Huang, L.C. Hartmann, S.H. Kaufmann, and D.I. Smith Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer Cancer Res. 61 2001 4258 4265
-
(2001)
Cancer Res.
, vol.61
, pp. 4258-4265
-
-
Shridhar, V.1
Bible, K.C.2
Staub, J.3
Avula, R.4
Lee, Y.K.5
Kalli, K.6
Huang, H.7
Hartmann, L.C.8
Kaufmann, S.H.9
Smith, D.I.10
-
82
-
-
19144372995
-
Nuclear localisation of glutathione S-transferase pi is an evaluation factor for drug resistance in gynaecological cancers
-
Y. Soh, S. Goto, M. Kitajima, S. Moriyama, K. Kotera, T. Nakayama, H. Nakajima, T. Kondo, and T. Ishimaru Nuclear localisation of glutathione S-transferase pi is an evaluation factor for drug resistance in gynaecological cancers Clin. Oncol. (R. Coll. Radiol.) 17 2005 264 270
-
(2005)
Clin. Oncol. (R. Coll. Radiol.)
, vol.17
, pp. 264-270
-
-
Soh, Y.1
Goto, S.2
Kitajima, M.3
Moriyama, S.4
Kotera, K.5
Nakayama, T.6
Nakajima, H.7
Kondo, T.8
Ishimaru, T.9
-
83
-
-
16344392867
-
Pulsatile administration of the epidermal growth factor receptor inhibitor gefitinib is significantly more effective than continuous dosing for sensitizing tumors to paclitaxel
-
D.B. Solit, Y. She, J. Lobo, M.G. Kris, H.I. Scher, N. Rosen, and F.M. Sirotnak Pulsatile administration of the epidermal growth factor receptor inhibitor gefitinib is significantly more effective than continuous dosing for sensitizing tumors to paclitaxel Clin. Cancer Res. 11 2005 1983 1989
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 1983-1989
-
-
Solit, D.B.1
She, Y.2
Lobo, J.3
Kris, M.G.4
Scher, H.I.5
Rosen, N.6
Sirotnak, F.M.7
-
84
-
-
20244388653
-
Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies
-
N.L. Spector, W. Xia, H. Burris III, H. Hurwitz, E.C. Dees, A. Dowlati, and B. O'Neil Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies J. Clin. Oncol. 23 2005 2502 2512
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 2502-2512
-
-
Spector, N.L.1
Xia, W.2
Burris III, H.3
Hurwitz, H.4
Dees, E.C.5
Dowlati, A.6
O'Neil, B.7
-
85
-
-
0142135067
-
Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells
-
F. Spinella, L. Rosano, V. Di Castro, M.R. Nicotra, P.G. Natali, and A. Bagnato Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells J. Biol. Chem. 278 2003 41294 41301
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 41294-41301
-
-
Spinella, F.1
Rosano, L.2
Di Castro, V.3
Nicotra, M.R.4
Natali, P.G.5
Bagnato, A.6
-
86
-
-
20444461499
-
Demethylation of the MCJ gene in stage III/IV epithelial ovarian cancer and response to chemotherapy
-
G. Strathdee, J.K. Vass, K.A. Oien, N. Siddiqui, J. Curto-Garcia, and R. Brown Demethylation of the MCJ gene in stage III/IV epithelial ovarian cancer and response to chemotherapy Gynecol. Oncol. 97 2005 898 903
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 898-903
-
-
Strathdee, G.1
Vass, J.K.2
Oien, K.A.3
Siddiqui, N.4
Curto-Garcia, J.5
Brown, R.6
-
87
-
-
0038386613
-
Src family kinases in tumor progression and metastasis
-
J.M. Summy, and G.E. Gallick Src family kinases in tumor progression and metastasis Cancer Metastasis Rev. 22 2003 337 358
-
(2003)
Cancer Metastasis Rev.
, vol.22
, pp. 337-358
-
-
Summy, J.M.1
Gallick, G.E.2
-
88
-
-
0034742120
-
AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells
-
M. Sun, G. Wang, J.E. Paciga, R.I. Feldman, Z.Q. Yuan, X.L. Ma, S.A. Shelley, R. Jove, P.N. Tsichlis, S.V. Nicosia, and J.Q. Cheng AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells Am J Pathol. 159 2001 431 437
-
(2001)
Am J Pathol.
, vol.159
, pp. 431-437
-
-
Sun, M.1
Wang, G.2
Paciga, J.E.3
Feldman, R.I.4
Yuan, Z.Q.5
Ma, X.L.6
Shelley, S.A.7
Jove, R.8
Tsichlis, P.N.9
Nicosia, S.V.10
Cheng, J.Q.11
-
89
-
-
0842334017
-
DNA methylation and cancer therapy
-
M. Szyf DNA methylation and cancer therapy Drug Resist. Update 6 2003 341 353
-
(2003)
Drug Resist. Update
, vol.6
, pp. 341-353
-
-
Szyf, M.1
-
90
-
-
0038037108
-
Role of Jun and Jun kinase in resistance of cancer cells to therapy
-
I. Vasilevskaya, and P.J. O'Dwyer Role of Jun and Jun kinase in resistance of cancer cells to therapy Drug Resist. Update 6 2003 147 156
-
(2003)
Drug Resist. Update
, vol.6
, pp. 147-156
-
-
Vasilevskaya, I.1
O'Dwyer, P.J.2
-
91
-
-
16544388297
-
Tlk-286
-
C.F. Verschraegen, H.O. Smith, F.C. Lee, C. Cathcart, and J.P. Norenberg Tlk-286 IDrugs 7 2004 771 781
-
(2004)
IDrugs
, vol.7
, pp. 771-781
-
-
Verschraegen, C.F.1
Smith, H.O.2
Lee, F.C.3
Cathcart, C.4
Norenberg, J.P.5
-
92
-
-
20544468698
-
Transcriptional repression of WEE1 by Kruppel-like factor 2 is involved in DNA damage-induced apoptosis
-
F. Wang, Y. Zhu, Y. Huang, S. McAvoy, W.B. Johnson, T.H. Cheung, T.K. Chung, K.W. Lo, S.F. Yim, M.M. Yu, H.Y. Ngan, Y.F. Wong, and D.I. Smith Transcriptional repression of WEE1 by Kruppel-like factor 2 is involved in DNA damage-induced apoptosis Oncogene 24 2005 3875 3885
-
(2005)
Oncogene
, vol.24
, pp. 3875-3885
-
-
Wang, F.1
Zhu, Y.2
Huang, Y.3
McAvoy, S.4
Johnson, W.B.5
Cheung, T.H.6
Chung, T.K.7
Lo, K.W.8
Yim, S.F.9
Yu, M.M.10
Ngan, H.Y.11
Wong, Y.F.12
Smith, D.I.13
-
93
-
-
25844467877
-
Inhibitors of growth factor signalling
-
A.E. Wakeling Inhibitors of growth factor signalling Endocr. Relat. Cancer 12 Suppl. 1 2005 S183 S187
-
(2005)
Endocr. Relat. Cancer
, vol.12
, Issue.1 SUPPL.
-
-
Wakeling, A.E.1
-
94
-
-
7944239573
-
Molecular mechanisms of platinum resistance: Still searching for the Achilles' heel
-
R.P. Wernyj, and P.J. Morin Molecular mechanisms of platinum resistance: still searching for the Achilles' heel Drug Resist. Update 7 2004 227 232
-
(2004)
Drug Resist. Update
, vol.7
, pp. 227-232
-
-
Wernyj, R.P.1
Morin, P.J.2
-
95
-
-
0037229627
-
Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers
-
J.R. Wiener, T.C. Windham, V.C. Estrella, N.U. Parikh, P.F. Thall, M.T. Deavers, R.C. Bast, G.B. Mills, and G.E. Gallick Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers Gynecol. Oncol. 88 2003 73 79
-
(2003)
Gynecol. Oncol.
, vol.88
, pp. 73-79
-
-
Wiener, J.R.1
Windham, T.C.2
Estrella, V.C.3
Parikh, N.U.4
Thall, P.F.5
Deavers, M.T.6
Bast, R.C.7
Mills, G.B.8
Gallick, G.E.9
-
96
-
-
12344266609
-
Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease
-
J. Williams, P.C. Lucas, K.A. Griffith, M. Choi, S. Fogoros, Y.Y. Hu, and J.R. Liu Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease Gynecol. Oncol. 96 2005 287 295
-
(2005)
Gynecol. Oncol.
, vol.96
, pp. 287-295
-
-
Williams, J.1
Lucas, P.C.2
Griffith, K.A.3
Choi, M.4
Fogoros, S.5
Hu, Y.Y.6
Liu, J.R.7
-
97
-
-
4444328522
-
Role of the transcription factor Ets-1 in cisplatin resistance
-
L.A. Wilson, H. Yamamoto, and G. Singh Role of the transcription factor Ets-1 in cisplatin resistance Mol. Cancer Ther. 3 2004 823 832
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 823-832
-
-
Wilson, L.A.1
Yamamoto, H.2
Singh, G.3
-
98
-
-
1542298267
-
Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone.
-
P. Workman Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone. Cancer Lett. 206 2004 149 157
-
(2004)
Cancer Lett.
, vol.206
, pp. 149-157
-
-
Workman, P.1
-
99
-
-
18144406143
-
Regulation of HtrA2/Omi by X-linked inhibitor of apoptosis protein in chemoresistance in human ovarian cancer cells
-
X. Yang, H. Xing, Q. Gao, G. Chen, Y. Lu, S. Wang, and D. Ma Regulation of HtrA2/Omi by X-linked inhibitor of apoptosis protein in chemoresistance in human ovarian cancer cells Gynecol. Oncol. 97 2005 413 421
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 413-421
-
-
Yang, X.1
Xing, H.2
Gao, Q.3
Chen, G.4
Lu, Y.5
Wang, S.6
Ma, D.7
-
100
-
-
3843115557
-
Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancer
-
X. Yang, F. Zheng, H. Xing, Q. Gao, W. Wei, Y. Lu, S. Wang, J. Zhou, W. Hu, and D. Ma Resistance to chemotherapy-induced apoptosis via decreased caspase-3 activity and overexpression of antiapoptotic proteins in ovarian cancer J. Cancer Res. Clin. Oncol. 130 2004 423 428
-
(2004)
J. Cancer Res. Clin. Oncol.
, vol.130
, pp. 423-428
-
-
Yang, X.1
Zheng, F.2
Xing, H.3
Gao, Q.4
Wei, W.5
Lu, Y.6
Wang, S.7
Zhou, J.8
Hu, W.9
Ma, D.10
-
101
-
-
3142773418
-
Oncogenic H-Ras up-regulates expression of ERCC1 to protect cells from platinum-based anticancer agents
-
C.K. Youn, M.H. Kim, H.J. Cho, H.B. Kim, I.Y. Chang, M.H. Chung, and H.J. You Oncogenic H-Ras up-regulates expression of ERCC1 to protect cells from platinum-based anticancer agents Cancer Res. 64 2004 4849 4857
-
(2004)
Cancer Res.
, vol.64
, pp. 4849-4857
-
-
Youn, C.K.1
Kim, M.H.2
Cho, H.J.3
Kim, H.B.4
Chang, I.Y.5
Chung, M.H.6
You, H.J.7
-
102
-
-
27644552998
-
Difference in expression of Bcl-2 and Bcl-xl genes in cisplatin-sensitive and cisplatin-resistant human in ovarian cancer cell lines
-
L. Yu, and Z. Wang Difference in expression of Bcl-2 and Bcl-xl genes in cisplatin-sensitive and cisplatin-resistant human in ovarian cancer cell lines J. Huazhong Univ. Sci. Technol. Med. Sci. 24 2004 151 153
-
(2004)
J. Huazhong Univ. Sci. Technol. Med. Sci.
, vol.24
, pp. 151-153
-
-
Yu, L.1
Wang, Z.2
-
103
-
-
0038342509
-
AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: Implication of AKT2 in chemoresistance
-
Z.Q. Yuan, R.I. Feldman, G.E. Sussman, D. Coppola, S.V. Nicosia, and J.Q. Cheng AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance J. Biol. Chem. 278 2003 23432 23440
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23432-23440
-
-
Yuan, Z.Q.1
Feldman, R.I.2
Sussman, G.E.3
Coppola, D.4
Nicosia, S.V.5
Cheng, J.Q.6
-
104
-
-
0034604067
-
Frequent activation of Akt2 and induction of apoptosis by inhibition of phopsphoinositide-3-OH kinase/Akt pathway in human ovarian cancer
-
Z.Q. Yuan, M. Sun, R.I. Feldman, G. Wang, X. Ma, C. Jiang, D. Coppola, S.V. Nicosia, and J.Q. Cheng Frequent activation of Akt2 and induction of apoptosis by inhibition of phopsphoinositide-3-OH kinase/Akt pathway in human ovarian cancer Oncogene 19 2000 2324 2330
-
(2000)
Oncogene
, vol.19
, pp. 2324-2330
-
-
Yuan, Z.Q.1
Sun, M.2
Feldman, R.I.3
Wang, G.4
Ma, X.5
Jiang, C.6
Coppola, D.7
Nicosia, S.V.8
Cheng, J.Q.9
-
105
-
-
18144382602
-
Reversal of multidrug resistance by small interfering double-stranded RNAs in ovarian cancer cells
-
T. Zhang, M. Guan, H.Y. Jin, and Y. Lu Reversal of multidrug resistance by small interfering double-stranded RNAs in ovarian cancer cells Gynecol. Oncol. 97 2005 501 507
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 501-507
-
-
Zhang, T.1
Guan, M.2
Jin, H.Y.3
Lu, Y.4
-
106
-
-
0038031592
-
Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1
-
C. Zhou, J.L. Smith, and J. Liu Role of BRCA1 in cellular resistance to paclitaxel and ionizing radiation in an ovarian cancer cell line carrying a defective BRCA1 Oncogene 22 2003 2396 2404
-
(2003)
Oncogene
, vol.22
, pp. 2396-2404
-
-
Zhou, C.1
Smith, J.L.2
Liu, J.3
|