Model systems of epithelium mesenchyme transitions

Cells Tissues Organs

Volumn 156, Issue 3, 1996, Pages 227-239

  Boyer, B ^a   Valles A M ^a   Thiery, J P ^a  

^a INSTITUT CURIE   (France)

Author keywords

Cell scattering; Epithelial mesenchymal transitions; Extracellular matrix; Growth factors; Signaling pathway

Indexed keywords

CYTOKINE; GROWTH FACTOR;

ANIMAL TISSUE; CELL DIFFERENTIATION; EPITHELIUM; EXTRACELLULAR MATRIX; MESENCHYME; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL MOVEMENT; EPITHELIUM; EXTRACELLULAR MATRIX; GAP JUNCTIONS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH SUBSTANCES; HUMANS; MESODERM; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION;

EID: 0030477385     PISSN: 14226405     EISSN: 14226421     Source Type: Journal    
DOI: 10.1159/000147849     Document Type: Article

References (86)

1. Bade, E.G., S. Fcindlcr (1988) Liver epithelial cell migration induced by epidemial growth factor or transforming growth factor alpha is associated with changes in the gene expression of secreted proteins. In vitro Cell Dev Biol 24; 149-154.
2. Bade, E.G., B. Nitzgen (1985) Extracellular matrix (ECM) modulates the F.GF-induced migration of liver epithelial cells in serum-free, hormone-supplemented medium. In vitro Cell Dev Biol 21; 245-248.
3. Barrandon, Y., H. Green (1987) Cell migration is essential for sustained growth of keratinocyte colonies; The roles of transforming growth factor-alpha and epidermal growth factor. Cell 50; 1131-1137.
4. Behrens, J., L. Vakaet, R. Friis, E. Winterhager, F. Van Roy, M.M. Marcel, W. Birchmeicr (1993) Loss of epithelial differentiation and gain of invasiveness correlate with tyrosine phosphorylation of the E-eadhcrin/p-catcnm complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol 120; 757-766.
5. Benali, R., F. Dupuit, M. Chevillard, J. Jacquot, B. Have, E. Puchellc (1991) Modulations of the epithelial phenotype and functional activity of cultured bovine tracheal gland cells; Dependence on the culture medium and passage number. Biol Cell 73;49-56.
6. Berdichevsky, F., C. Gilbert, M. Shearer, J. Taylor-Papdimitriou (1992) Collagen-induced rapid morphogenesis of human mammary epithelial cells; The role of the u.2 I jntegrin. J Cell Sci 102;437-446.
7. Blay, H., K.D. Brown (1985) Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells. J Cell Physiol 124; 107-112.
8. Boyer, B., S. Dufour, J.P. Thicry (1991) E-cadhcrin expression during the acidic FGF-induced dispersion of a rat bladder carcinoma cell line. Exp Cell Res 201;347-357.
9. Boyer, B., J.P. Thiery (1993) Cyclic AMP distinguishes between two functions of acidic FGF in a rat bladder carcinoma cell line. J Cell Biol 120; 767-776.
10. Boyer, B., G.C. Tucker, A.M. Valles, W.W. Franke, J.P. Thiery (1989) Rearrangements of desmo-sotttal and cytoskelctal proteins during the transition from epithelial to fibroblastoid organization in cultured rat bladder carcinoma cells. J Cell Biol 109; 1495-1509.
11. Bradley, R.S., P. Cowin, A.M.C. Brown (1993) Expression of Will-1 in PC 12 cells results in modulation of plakoglobin and E-cadhcrin and increased cellular adhesion. J Cell Biol 123; 1857-1865.
12. Bringuier, P.P, R. Umbas, H.E. Schaafsma, H.F.M. Karlhaus, F.M.J. Debryune, J.A. Schalken (1993) Decreased E-cadherin immunoreac-tivity correlates with poor survival in patients with bladder tumors. Cancer Res 53; 3241-3245.
13. Burridge, K., K. Fath, T. Kelly, G. Nuckolls, C. Turner (1988) Focal adhesions; Transmembrane junctions between the extracellular matrix and the cytoskclcton. Ann Rev Cell Biol 4; 487-525.
14. Chan, B.M.C., N. Matsuura, Y. Takada, B.R. Zetler, M.F. Hemler (1991) In vitro and in vivo consequences of Vl.A-2 expression on rhabdomyosarcoma cells. Science 251; 1600-1602.
15. Chen, P., H. Xie, M.C. Sekar, K. Gupta, A. Wells (1994) Epidermal growth factor receptor-mediated cell motility; Phospholipase C' activity is required, but mitogen-activated protein kinase activity is not sufficient for induced cell movement. J Cell Biol 127; 847-857.
16. Clyman, R.I., K.G. Peters, Y.Q. Chen, J. Escobedo, L.T. Williams, H.E. Ives, E. Wilson (1994) Phospholipase Cy activation, phosphotidyli-nositol hydrolysis, and calcium mobilization are not required for FGF receptor-mediated chcmotaxis. Cell Adhcs Commun J. 333-342.
17. FAK. Mol Cell Biol 14; 147-155.
18. Delannet, M., J.L. Du band (1992) Transforming growth factor-p control of cell-substratum adhesion during avian neural crest cell emigration in vitro. Development 116; 275-287.
19. Diamond, M.S., T.A. Springer (1994) The dynamic regulation of integrin adhesiveness. Cilrr Opin Cell Biol 4;506-517.
20. Dikic, I., J. Schlcssinger, I. Lax (1994) PC 12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation. Curr Opin Cell Biol J. 8: 702-708.
21. Duband, J.L., F. Monier, M. Delannet, D. New-green (1995) Epithelium-mesenchyme transition during neural crest development. Acta Anal 154; 63-78.
22. Dulbecco, R., M. I lenahan, M. Bowman, S. Okada, H. Battifora, M. Unger (1981) Generation of fibroblast-like cells from cloned epithelial mammary cells in vitro; A possible new type. Proc Nat Acad Sci USA 78; 2345-2349.
23. El Badry, O.M., C. Minniti, E.C. Kohn, P.J. Houghton, W.H. Daughaday, L.J. Helman (1990) Insulin-like growth factor II acts as an autocrine motility factor in human rhabdomyosarcoma tumors. Cell Growth Different Vol I; 325-331.
24. Erickson, C.A. (1990) Cell migration in the embryo and adult organism. Curr Opin Cell Biol 2; 67-74.
25. Fabre, M., A.G. de Herrcros (1993) Phorbol ester-induced scattering of HT-29 human intestinal cancer cells is associated with down-modulation of E-cadherin. J Cell Sci 106; 513-522.
26. Fox. PL, G. Sa, S.F. Dobrowolski, D.W. Stacey (1994) The regulation of endothelial cell motility hy p2l/uv. Oncogene 9; 3519-3526.
27. Gamallo, C., J. Palacios, A. Suarez, A. Pizarro, P. Navarro, M. Quintanilla, A. Cano (1993) Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma. Am J Pathol 142;987-993.
28. Gavrilovic, J., G. Moens, J.P. Thiery, J. Jouanneau (1996) Expression of transfected transforming growth factor alpha induces a motile fibroblast-like phenotype with extracellular matrixdegrading potential in a rat bladder carcinoma cell line. Cell Regul 1;1003-1014.
29. Geiger. IL, S. Yehuda-Levenbcrg, A.D. Bershadsky (1995) Molecular interactions in the sub-membrane plaque of cell-cell and cell-matrix adhesions. Acta Anal 154;46-62.
30. Geimer, P., E.G. Bade (1991) The epidermal growth factor-induced migration of rat liver epithelial cells associated with a transient inhibition of DNA synthesis. J Cell Sci 100;349-355.
31. Graziani, A., P. dallaZonca, PM. Comoglio (1993) Hepuiocyte growth faclor/scattcr factor stimulates the Ras-guanine nucleotide exchanger. J Biol Client 268;9165-9168.
32. Groiendorst, G.R. (1984) Alteration of the chemo-1 act it response of NIH/3T3 cells to PDGF by growth factors, transformation, anti tumor promotors. Cell 36; 279.
33. Gumbiner, B.M. (1993) Proteins associated with the cytoplasmic surface of adhesion molecules. Neuron 11;551-564.
34. Hamaguchi, M., N. Matsuyoshi, Y. Ohnishi, B. Goloh, M. Takcichi, Y. Nagai (1993) P60' causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J 12;307-314.
35. Hay, E.D. (1993) Extracellular matrix alters epithelial differentiation. Curr Opin Cell Biol 5. 1029-1035.
36. Hay, E.D. (1995) An overview of epithelio-mesen-chymal transformation. Acta Anat 154; 8-20.
37. Hinck, L., W.J. Nelson, J. Papkoff (1994) Win-1 modulates cell-cell adhesion in mammalian cells by stabilizing p-catenin binding to the cell adhesion protein cadhcrin. J Cell Biol 124; 729-741.
38. Hordijk, P.l., I. Verlaan, E.J. van Corven, W.H. Moolenaar (1994) Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts. J Biol Cltem 269. 645-651.
39. Hugucs, F.J., A.G. McCulloch (1991) Quantification of chemotactic response of quiescent and proliferating fibroblasts in Boytlen chambers by computer-assisted image analysis. J His-tochem Cytoehem 39;243-246.
40. Hynes, R.O. (1992) Integrins; Versatility, modulation, and signaling in cell adhesion. Cell 69; 11-25.
41. Juliano, R.L., J.A. Varner (1993) Adhesion molecules in cancer; The role of integrins. Curr Opin Cell Biol 5;812-818.
42. Kawanishi, J., J. Kalo, K. Sasaki, S. Fujii, N. Watanabe, Y. Niitsu(l998) Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the p-catenin gene in a human cancer cell line. HCS-39. Mol Cell Biol 15;1175-1181.
43. Klein, C.E., T. Sleinmayer, D. Kaufmann, L. Weber, E.-B. Blocker (1991) Identification of a melanoma progression antigen as integral VLA-2. J Invest Dermatol 96;281-284.
44. Klemke, R.L., M. Yebra, E.M. Bayna, D.A. Chercsh (1994) Receptor tyrosine kinase signaling required for integrin αVβ5 cell motility but not adhesion on vitronectin. J Cell Biol 127; 859-866.
45. Lin, C.Q., M.J. Bissell (1993) Multi-faceted regulation of cell differentiation by extracellular matrix. FASEB J 7; 737-743.
46. Manske, M., S. Fcindler, E.G. Bade (1990) The epidermal growth factor-induced cell migration and expression of the 47.0(H) M, secreted glycoprotein EIP-I of rat liver epithelial cells are down-regulated by cyclic AMP. EurJ Cell Biol 52;201-206.
47. Matsuyoshi, N., M. Hamaguchi, S. Taniguchi, A. Nagaluchi, S. Tsukita, M. Takcichi (1992) Cad-herin-mediated cell-cell adhesion is perturbed by v-.sto tyrosine phosphorylation in metastatic fibroblasts. J Cell Biol 118;703-714.
48. Matthay, M.M., J.P. Tliiery, F. Lafont, M.F. Stampfer, B. Boyer (1993) Transient effect of epidermal growth factor on the motility of an immortalized mammary epithelial cell line. J Cell Sci 106;869-878.
49. Mayer, B., J.P. Johnson, F. Leitl, K.W. Jauch, M.M. Heiss, F.W. Schildberg, W. Birchmcicr, I. Funke (1993) E-cadherin expression in primary and metastatic gastric cancer; Down-regulation correlates with cellular dedifferentiation and glandular disintegration. Cancer Res 53; 1690-1695.
50. McNeill, H., M. Ozawa, R. Kemler, W.J. Nelson (1990) Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity. Cell 62. 309-316.
51. Mege, R.M., F. Malsuzaki, W. Gallin, J.l. Goldberg, B. Cunningham, G.M. Edelman (1988) Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules. Proe Nat Acad Sei USA 85;7274-7278.
52. Mictlincn, P.J., R. Ebner, A.R. Lopez, R. Derynck (1994) TGF-ß induced Iransdifferentiation of mammary epithelial cells to mesenchymal cells; Involvement of type I receptors. J Cell Biol 127; 2021-2036.
53. Neugebauer, K.M., K.J. Tomaselli, J. Lilien, L.F. Reichard! (1988) N-cadherin, NCAM.and integrins promote retinal ncurite outgrowth on astrocytes in vitro. J Cell Biol 107; 1177-1187.
54. Nieto, M.A., M.G. Sargent, DG. Wilkinson, J. Cooke (1994) Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science 264; 835-839.
55. Oka, H., H. Shiozaki, K Kobayashi, M. Inoue, H. Tahara, T. Kobayashi, Y. Takatsuka, N. Matsuyoshi, S. Ilirano, M. Takcichi, T. Mori(1993) Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res 53; 1696-1701.
56. Potts, J.D., J.M. Dagle, J.A. Wälder, D.L. Weeks, R.B. Runyan (1991) Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified anti-sense oligodeoxynucleotide to transforming growth factor 53. Proc Nat Acad Sci USA 88; 1516-1520.
57. Potts, J.D., R.B. Runyan (1989) Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor-p. Dev Biol 134; 392-401.
58. Prieto, A.L., K.L. Crossin (1995) Cell-cell adhesion molecules in epithelial-mesenchymal transformations. Acta Anat 154;21-33.
59. Reynolds, A.B., J. Daniel, I’D. MeCrea, M.J. Wheelock, J. Wu, Z. Zhang (1994) Identification of a new catenin; the tyrosine kinase substrate pl2β- associates with E-cadherin complexes. Mol Cell Biol 14; 8333-8342.
60. rgn. is related to cadherin-binding factors ß-catcnin. plakoglobin and armadillo. Oncogene 7;2439-2445.
61. Rosen, E.M., S.K. Nigam, I.D. Goldberg (1994) Scatter factor and the c-met receptor; A paradigm for mesenchymal/epilhclial interaction. J Cell Biol 127; 1783-1787.
62. Rothenpieler, U.W., G.R. Dressier (1993) Pax-2 is required for mesenchyme-to-epilhclium conversion during kidney development. Development 119;711-720.
63. Rubinfcld, B., B. Souza, I. Albert, Ü. Müller, S.H. Chamberlain, FR. Masiarz, S. Muncmitsu, P. Polakis (1993) Association of the APC gene product with p-catenin. Science 262; 1731-1734.
64. Runyan, R.B., J.D Potts, R.V. Sharma, C.P. Loeber, J.J. Chiang, R.C. Bhalla (1990) Signal transduction of a tissue interaction during embryonic heart development. Cell Rcgul Vol I; 301-313.
65. Schiro, J.A., B.M.C. Chan, W.T. Roswit, P.D. Kass-ner, A.P. Pentland, M.E. Hcmler, A.Z. Eisen, T.S. Kupper (1991) Integrin a2pl (VLA-2) mediates reorganization and contraction of collagen matrices by human cells. Cell 67; 403-410.
66. Schlaepfer, D.D., S.K. Hanks, T. Humer, P. van der Geer (1994) Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372; 786-791.
67. Seufferlein, T., E. Rozengurt (1994) Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin, and p 130. J Biol Chem 269;9345-9351.
68. Shackelford, G.M., K. Willert, J. Wang, H.E. Various; (1993) The Wnt-1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC 12 cells. Neuron 11; 865-875.
69. Shibamoto, S., M. Hahakawa, K. Takeuchi, T. Hori, N. Oku, K. Miyazawa, N. Kitamura, M. Takcichi, F. Ito (1994) Tyrosine phosphorylation of P-catenin and plakoglobin enhanced by hépatocyte growth factor and epidermal growth factor in human carcinoma cells. Cell Adhes Commun 1; 295-305.
70. Shimonaka, M., Y. Yamaguchi (1994) Purification and biological characterization of epitaxin, a fibroblast-derived motility factor for epithelial cells. J Biol Chem 269;14284-14289.
71. Shimoyama, Y., A. Nagafuchi, S. Fujita, M. Goloh, M. Takeichi, S. Tsukita, S. Hirohashi (1992) Cadhcrin dysfunction in a human cancer cell line; possible involvement of loss of oc-catcnin expression in reduced cell-cell adhesiveness. Cancer Res 52;5770-5774.
72. Shiota, G., D.B. Rhoads, T.C. Wang, T. Nakamura, E.V. Schmidt (1992) Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells. Proc Nat Acad Sci USA 89;373-377.
73. Sommers, C., E.P. Gclmann, R. Kemler, P. Cowin, S.W. Byers (1994) Alterations in P-catenin phosphorylation and plakoglobin expression in human breast cancer cells. Cancer Res 54; 3544-3552.
74. Stampfer, M.R., J.C. Bartley (1988) In Lippmann M. R Dickson (eds); Breast Cancer; Cellular and Molecular Biology. Boston. Kluwer Academic Publishers, pp 1-24.
75. Stanton, B.R., A.S. Perkins, L. Tessarollo, D.A. Sassoon, L.F. Parada (1992) Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop. Genes Dev 6; 2235-2247.
76. Strackc, M.L., E.C. Kohn, S.A. Aznavoorian, L.L. Wilson, D. Salomon, H.C. Krutzsch, L.A. Lioila, E. Schiffman (1988) Insulin-like growth factors stimulate chcmotaxis in human melanoma cells. Biochem Biophys Res Commun 153; 1076-1083.
77. Su, L.-K., B. Vogelstein, K.W. Kinzler (1993) Association of the ABC' tumor suppressor protein with catenins. Science 262; 1734-1737.
78. Traverse, S., K. Seedorf, H. Paterson, C.J. Marshall, P. Cohen, A. Ullrich (1994) EOF triggers neuronal differentiation of PC 12 cells that overexpress the EGF receptor. Curr Opin Cell Biol 4;694-701.
79. Tsarfaty, I., S. Rong, J.H. Resau, S. Rulong, P. Pinto da Silva, G.F. Vande Woude (1994) The met proto-oncogene mesenchymal to epithelial cell conversion. Science 263;98-101.
80. Tucker, G.C., B. Boyer, J. Gavrilovic, U. Emonard, J.P. Thiery (1990) Collagen-mediated dispersion of NBT-II rat bladder carcinoma cells. Cancer Res 50; 129-137.
81. Tucker, G.C., B. Boyer, A.M. Valles, J.P. Thiery (1991) Combined effects of extracellular matrix and growth factors on NBT-II rat bladder carcinoma cell dispersion. J Cell Sci 100; 371-380.
82. Valles, A.VI., B. Boyer, J. Badet, G.C. Tucker, D. Barritaull, J.P. Thiery (1990a) Acidic fibroblast growth factor is a modulator of epithelial plasticity in a rat bladder carcinoma cell line. Proc Nat Acad Sci USA 87; 1124-1128.
83. Valles, A.M., G.C. Tucker, J.P. Thiery, B. Boyer (1990b) Alternative patterns of mitogenesis and cell scattering induced by acidic FGF as a function of cell density in a rat bladder carcinoma cell line. Cell Regul 1; 975-988.
84. Woolf, A.S., J. Kolatsi-Joannou, P. Hardman, E. Andermacher, C. Moorby, L.G. Fine, P.S. Jat, M.D. Noble, E. Ghcrardi (1995) Roles of hépatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J Cell Biol 128; 171-184.
85. Zachary, I., J. Sinnett-Smith, E. Rozengurt (1992) Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. J Biol Chcm 267; 19031-19034.
86. Zachary, I., E. Rozengurt (1992) Focal adhesion kinase (p 125FAK); A point of convergence in the action of neuropeptides, integrins. and oncogenes. Cell 71; 891-894.