Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation

Biochemical Pharmacology

Volumn 70, Issue 12, 2005, Pages 1735-1743

  Ferri, Nicola ^a   Clerici, Francesca ^a   Yokoyama, Kohei ^b   Pocar, Donato ^a   Corsini, Alberto ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Atherosclerosis; Cell proliferation; Farnesol; Farnesyl transferase inhibitor; Farnesylation; Smooth muscle cell

Indexed keywords

FARNESOL; ISOTHIAZOLE DERIVATIVE; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; THYMIDINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CHEMICAL BOND; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; EXPERIMENTAL MODEL; FLOW CYTOMETRY; IC 50; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ALKYL AND ARYL TRANSFERASES; ANIMALS; CELL CYCLE; CELL PROLIFERATION; ENZYME INHIBITORS; FARNESOL; MALE; MUSCLE, SMOOTH, VASCULAR; PROTEIN ISOPRENYLATION; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 27744443732     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.09.022     Document Type: Article

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