Mechanistic studies of rat protein farnesyltransferase indicate an associative transition state

Biochemistry

Volumn 39, Issue 10, 2000, Pages 2593-2602

  Huang, Chih Chin ^a,c   Hightower, Kendra E ^a   Fierke, Carol A ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; COBALT; FLUORINE; MAGNESIUM; METAL; PROTEIN FARNESYLTRANSFERASE; SULFUR; ZINC;

ALKYLATION; ARTICLE; BINDING AFFINITY; CATALYSIS; DISSOCIATION CONSTANT; DNA REPAIR; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; RAT;

ALKYL AND ARYL TRANSFERASES; ANIMALS; BINDING SITES; CADMIUM; COBALT; FLUORINE RADIOISOTOPES; KINETICS; MAGNESIUM; PEPTIDES; POLYISOPRENYL PHOSPHATES; PROTEIN ISOPRENYLATION; RATS; ZINC;

ESCHERICHIA COLI; MAMMALIA;

EID: 0034646238     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992356x     Document Type: Article

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