Differential ion current activation by human 5-HT1A receptors in Xenopus oocytes: Evidence for agonist-directed trafficking of receptor signalling

Neuropharmacology

Volumn 49, Issue 7, 2005, Pages 963-976

  Heusler, Peter ^a   Pauwels, Petrus J ^a   Wurch, Thierry ^a,c   Newman Tancredi, Adrian ^a   Tytgat, Jan ^b   Colpaert, Francis C ^a   Cussac, Didier ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c Centre d'Immunologie Pierre Fabre   (France)

Author keywords

5 HT1A receptor; Agonist trafficking; Electrophysiology; GPCR; Xenopus oocytes

Indexed keywords

4 DIPROPYLAMINO 1,3,4,5 TETRAHYDROBENZ[CD]INDOLE 6 CARBOXAMIDE; F 13714; FLESINOXAN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; INWARDLY RECTIFYING POTASSIUM CHANNEL; ION CHANNEL; N [4 [5 [3 (2 AMINOETHYL) 1H INDOL 5 YL] 1,2,4 OXADIAZOL 3 YL]BENZYL]METHANESULFONAMIDE; PERTUSSIS TOXIN; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ION CURRENT; NONHUMAN; OOCYTE; OSCILLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; XENOPUS;

ANIMALS; CHLORIDE CHANNELS; ELECTROPHYSIOLOGY; FEMALE; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GUANOSINE DIPHOSPHATE; HUMANS; ION CHANNELS; LIGANDS; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PERTUSSIS TOXIN; PLASMIDS; RECEPTOR, SEROTONIN, 5-HT1A; RNA; SEROTONIN; SEROTONIN AGONISTS; SIGNAL TRANSDUCTION; THIONUCLEOTIDES; XENOPUS LAEVIS;

EID: 27144451243     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2005.05.001     Document Type: Article

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