Using gadolinium to identify stretch-activated channels: Technical considerations

American Journal of Physiology - Cell Physiology

Volumn 275, Issue 2 44-2, 1998, Pages

  Caldwell, Ray A ^a   Clemo, Henry F ^a   Baumgarten, Clive M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chelation; Lanthanides; Mechanoelectrical feedback; Mechanosensitive channels

Indexed keywords

BICARBONATE; BUFFER; EGTAZIC ACID; GADOLINIUM; ION CHANNEL; LANTHANIDE;

ACCURACY; ARTICLE; CHANNEL GATING; CHELATION; IONIC STRENGTH; PRIORITY JOURNAL;

EID: 0031848597     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1998.275.2.c619     Document Type: Article

References (41)

1. Biagi, B. A., and J. J. Enyeart. Gadolinium blocks low- and high-threshold calcium currents in pituitary cells. Am. J. Physiol. 259 (Cell Physiol. 28): C515-C520, 1990.
2. Bleakman, D., D. Bowman, C. P. Bath, P. F. Brust, E. C. Johnson, C. R. Deal, R. J. Miller, S. B. Ellis, M. M. Harpold, and M. Hans. Characteristics of a human N-type calcium channel expressed in HEK293 cells. Neuropharmacology 34: 753-765, 1995.
3. Boland, L. M., T. A. Brown, and R. Dingeldine. Gadolinium block of calcium channels; influence of bicarbonate. Brain Res. 563: 142-150, 1991.
4. - channels as well as nonselective, stretch-activated cation channels in Ehrlich ascites tumor cells. J. Membr. Biol. 129: 13-36, 1992.
5. Edsall, J. T., and J. Wyman. Biophysical Chemistry. Thermodynamics, Electrostatics, and the Biological Significance of the Properties of Matter. New York: Academic, 1958, vol. 1, p. 555-561.
6. Elinder, F., and P. Arhem. Effects of gadolinium on ion channels in the myelinated axon of Xenopus laevis: four sites of action. Biophys. J. 67: 71-83, 1994.
7. Evans, C. H. Biochemistry of the Lanthanides. New York: Plenum, 1990, p. 18-22, 40-41, 85-210.
8. 2+ channels activated by membrane depolarization. J. Neurochem. 59: 1-9, 1992.
9. Hamill, O. P., and D. W. McBride, Jr. The pharmacology of mechanogated membrane ion channels. Pharmacol. Rev. 48: 231-252, 1996.
10. Hansen, D. E., M. Borganelli, G. P. Stacy, Jr., and L. K. Taylor. Dose-dependent inhibition of stretch-induced arrhythmias by gadolinium in isolated canine ventricles. Evidence for a unique mode of antiarrhythmic action. Circ. Res. 69: 820-831, 1991.
11. Hishikawa, K., T. Nakaki, T. Marumo, H. Suzuki, R. Kato, and T. Saruta. Pressure enhances endothelin-1 release from cultured human endothelial cells. Hypertension 25: 449-452, 1995.
12. Kongo, K., C. Pascarel, O. Cazorla, F. Cannier, J. Y. Le Guennec, and E. White. Gadolinium blocks the delayed rectifier potassium current in isolated guinea-pig ventricular myocytes. Exp. Physiol. 82: 647-656, 1997.
13. 2+ store in vascular endothelial cells. Am. J. Physiol. 273 (Cell Physiol. 42): C316-C322, 1997.
14. + channel in heart cells. Activation by arachidonic acid. J. Gen. Physiol. 100: 1021-1040, 1992.
15. Kim, D. Novel cation-selective mechanosensitive ion channel in the atrial cell membrane. Circ. Res. 72: 225-231, 1993.
16. + channels in cultured rat neuronal cells. J. Physiol. (Lond.) 483: 643-660, 1995.
17. Lacampagne, A., F. Gannier, J. Argibay, D. Garnier, and J. Y. Le Guennec. The stretch-activated ion channel blocker gadolinium also blocks L-type calcium channels in isolated ventricular myocytes of the guinea-pig. Biochim. Biophys. Acta 1191: 205-208, 1994.
18. Lansman, J. B. Blockade of current through single calcium channels by trivalent lanthanide cations. Effect of ionic radius on the rates of ion entry and exit. J. Gen. Physiol. 95: 679-696, 1990.
19. Le Guennec, J. Y., A. Lacampagne, and D. Garnier. Orthophosphate salts induce calcium current recovery from blockade by gadolinium in isolated guinea-pig ventricular myocytes. Exp. Physiol. 81: 577-585, 1996.
20. Magishi, K., J. Kimura, Y. Kubo, and Y. Abiko. Exogenous lysophosphatidylcholine increases a non-selective cation current in guinea-pig ventricular myocytes. Pflügers Arch. 432: 345-350, 1996.
21. Malek, A. M., and S. Izumo. Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress. J. Cell Sci. 109: 713-726, 1996.
22. Malysz, J., D. Richardson, L. Farraway, M.-O. Christen, and J. D. Huizinga. Generation of slow wave type action potentials in the mouse small intestine involves a non-L-type calcium channel. Can. J. Physiol. Pharmacol. 73: 1502-1511, 1995.
23. Marchenko, S. M., and S. O. Sage. A novel mechanosensitive cationic channel from the endothelium of rat aorta. J. Physiol. (Lond.) 498: 419-425, 1997.
24. Martell, A. E., and R. E. Smith. Critical Stability Constants. Inorganic Complexes. New York: Plenum, 1974, vol. 4, p. 37, 56-57, 269.
25. Millet, B., and B. G. Pickard. Gadolinium ion is an inhibitor suitable for testing the putative role of stretch-activated ion channels in geotropism and thigmotropism (Abstract). Biophys. J. 53: 155a, 1988.
26. Mlinar, B., and J. J. Enyeart. Block of current through T-type calcium channels by trivalent metal cations and nickel in neural rat and human cells. J. Physiol. (Lond.) 469: 639-652, 1993.
27. Morris, C. E. Mechanosensitive ion channels. J. Membr. Biol. 113: 93-107, 1990.
28. Nakazawa, K., M. Liu, K. Inoue, and Y. Ohno. Potent inhibition by trivalent cations of ATP-gated channels. Eur. J. Pharmacol. 325: 237-243, 1997.
29. Olson, J. E., C. Alexander, D. A. Feller, M. L. Clayman, and E. M. Ramnath. Hypoosmotic volume regulation of astrocytes in elevated extracellular potassium. J. Neurosci. Res. 40: 333-342, 1995.
30. Perrin, D. D., and B. Dempsey. Buffers for pH and Metal Ion Control. London: Chapman and Hall, 1974, p. 6, 18-20, 62-64, 104, 157-163.
31. + channel with fast-gating kinetics on human axons blocked by gadolinium ions. Neurosci. Lett. 169: 39-42, 1994.
32. Sachs, F. Mechanical transduction in biological systems. Crit. Rev. Biomed. Eng. 16: 141-169, 1988.
33. Sadoshima, J., T. Takahashi, L. Jahn, and S. Izumo. Roles of mechano-sensitive ion channels, cytoskeleton, and contractile activity in stretch-induced immediate-early gene expression and hypertrophy of cardiac myocytes. Proc. Natl. Acad. Sci. USA 89: 9905-9909, 1992.
34. Small, D. L., and C. E. Morris. Pharmacology of stretch-activated K channels in Lymnaea neurons. Br. J. Pharmacol. 114: 180-186, 1995.
35. Stacy, G. P., Jr., R. L. Jobe, L. K. Taylor, and D. E. Hansen. Stretch-induced depolarizations as a trigger of arrhythmias in isolated canine left ventricles. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H613-H621, 1992.
36. Takano, H., and S. A. Glantz. Gadolinium attenuates the upward shift of the left ventricular diastolic pressure-volume relation during pacing-induced ischemia in dogs. Circulation 91: 1575-1587, 1995.
37. Tokimasa, T., and R. A. North. Effects of barium, lanthanum and gadolinium on endogenous chloride and potassium currents in Xenopus oocytes. J. Physiol. (Lond.) 496: 677-686, 1996.
38. 4. Exp. Physiol. 79: 107-110, 1994.
39. Weast, R. C. Handbook of Chemistry and Physics (67th ed.). Boca Raton, FL: CRC, 1987, p. D-190.
40. Yamazaki, T., I. Komuro, S. Kudoh, Y. Zou, R. Nagai, R. Aikawa, H. Uozumi, and Y. Yazaki. Role of ionic channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy. Circ. Res. 82: 430-437, 1998.
41. Yang, X.-C., and F. Sachs. Block of stretch-activated ion channels in Xenopus oocytes by gadolinium and calcium ions. Science 243: 1068-1071, 1989.