A proteome-wide CDK/CRK-specific kinase inhibitor promotes tumor cell death in the absence of cell cycle progression

Chemistry and Biology

Volumn 12, Issue 10, 2005, Pages 1103-1115

  Caligiuri, Maureen ^a   Becker, Frank ^b   Murthi, Krishna ^a   Kaplan, Faith ^a   Dedier, Severine ^b   Kaufmann, Christine ^b   Machl, Andy ^a   Zybarth, Gabriele ^a   Richard, Judson ^a   Bockovich, Nick ^a   Kluge, Art ^a   Kley, Nikolai ^a,b  

^a GPC Biotech Inc   (United States)

^b GPC Biotech AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE; PROTEIN KINASE MODULATOR; PROTEOME; PYRIMIDINE DERIVATIVE; SIGNAL PEPTIDE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL STRAIN HCT116; CLASSIFICATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; HUMAN; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASES; DRUG SCREENING ASSAYS, ANTITUMOR; HCT116 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEOME; PYRIMIDINES;

EID: 26944481573     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2005.08.008     Document Type: Article

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