HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations

FEBS Letters

Volumn 579, Issue 25, 2005, Pages 5473-5480

  Di Stefano, Valeria ^a   Mattiussi, Marina ^a   Sacchi, Ada ^a   D'Orazi, Gabriella ^a,b  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

HIPK2; MDM2; Nuclear export; p53; Phosphorylation; Proteasomal degradation

Indexed keywords

HOMEODOMAIN INTERACTING PROTEIN KINASE 2; PROTEASOME; PROTEIN MDM2; PROTEIN P53;

APOPTOSIS; ARTICLE; CATALYSIS; CELL NUCLEUS; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INTRACELLULAR TRANSPORT; NULL ALLELE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; RNA INTERFERENCE; TRANSCRIPTION REGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; APOPTOSIS; CARRIER PROTEINS; CELL NUCLEUS; DNA DAMAGE; GENE EXPRESSION REGULATION; HUMANS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-MDM2; RNA INTERFERENCE; SERINE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 26844462296     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.09.008     Document Type: Article

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