메뉴 건너뛰기




Volumn 38, Issue 10, 2005, Pages 1455-1462

Multicellular spheroids of bone marrow stromal cells: A three-dimensional in vitro culture system for the study of hematopoietic cell migration

Author keywords

Bone marrow; Cell migration; Multicellular spheroid; Three dimensional culture

Indexed keywords

ALPHA4 INTEGRIN; BETA CATENIN; BETA1 INTEGRIN; CHEMOKINE RECEPTOR CXCR4; EPIDERMAL GROWTH FACTOR RECEPTOR; FOCAL ADHESION KINASE; INTEGRIN; LEUKOCYTE ELASTASE; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEINASE INHIBITOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1; UVOMORULIN; VASCULAR CELL ADHESION MOLECULE 1;

EID: 26644449418     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2005001000002     Document Type: Review
Times cited : (20)

References (56)
  • 1
    • 0033137070 scopus 로고    scopus 로고
    • Extracellular matrix and integrin signaling: The shape of things to come
    • Boudreau NJ & Jones PL (1999). Extracellular matrix and integrin signaling: the shape of things to come. Biochemical Journal, 339: 481-488.
    • (1999) Biochemical Journal , vol.339 , pp. 481-488
    • Boudreau, N.J.1    Jones, P.L.2
  • 2
    • 1842426730 scopus 로고    scopus 로고
    • Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
    • McBeath R, Pirone DM, Nelson CM et al. (2004). Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Developmental Cell, 6: 483-495.
    • (2004) Developmental Cell , vol.6 , pp. 483-495
    • McBeath, R.1    Pirone, D.M.2    Nelson, C.M.3
  • 3
  • 4
    • 0030953763 scopus 로고    scopus 로고
    • Geometric control of cell life and death
    • Chen CS, Mrksich M, Huang S et al. (1997). Geometric control of cell life and death. Science, 276: 1425-1428.
    • (1997) Science , vol.276 , pp. 1425-1428
    • Chen, C.S.1    Mrksich, M.2    Huang, S.3
  • 5
    • 0032435266 scopus 로고    scopus 로고
    • Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus
    • Lelièvre SA, Weaver VM, Nickerson JA et al. (1998). Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proceedings of the National Academy of Sciences, USA, 95: 14711-14716.
    • (1998) Proceedings of the National Academy of Sciences, USA , vol.95 , pp. 14711-14716
    • Lelièvre, S.A.1    Weaver, V.M.2    Nickerson, J.A.3
  • 8
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix to the third dimension
    • Cukierman E, Pankov R, Stevens DR et al. (2001). Taking cell-matrix to the third dimension. Science, 294: 1708-1712.
    • (2001) Science , vol.294 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.R.3
  • 10
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver VM, Petersen OW, Wang F et al. (1997). Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. Journal of Cell Biology, 137: 231-245.
    • (1997) Journal of Cell Biology , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3
  • 11
    • 0032217084 scopus 로고    scopus 로고
    • Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology
    • Wang F, Weaver VM, Petersen OW et al. (1998). Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proceedings of the National Academy of Sciences, USA, 95: 14821-14826.
    • (1998) Proceedings of the National Academy of Sciences, USA , vol.95 , pp. 14821-14826
    • Wang, F.1    Weaver, V.M.2    Petersen, O.W.3
  • 12
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • Coussens LM, Fingleton B & Matrisian LM (2002). Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science, 295: 2387-2392.
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 13
    • 0037455576 scopus 로고    scopus 로고
    • Compensation mechanism in tumor cell migration: Mesenchymal-amoeboid transition after blocking of pericellular proteolysis
    • Wolf K, Mazo I, Leung H et al. (2003). Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. Journal of Cell Biology, 160: 267-277.
    • (2003) Journal of Cell Biology , vol.160 , pp. 267-277
    • Wolf, K.1    Mazo, I.2    Leung, H.3
  • 14
    • 0030697292 scopus 로고    scopus 로고
    • Three-dimensional cell cultures: From molecular mechanisms to clinical applications
    • Mueller-Klieser W (1997). Three-dimensional cell cultures: from molecular mechanisms to clinical applications. American Journal of Physiology, 273: C1109-C1123.
    • (1997) American Journal of Physiology , vol.273
    • Mueller-Klieser, W.1
  • 16
    • 0033101647 scopus 로고    scopus 로고
    • Multicellular tumor spheroids: Intermediates between monolayer culture and in vivo tumor
    • Kunz-Shughart LA (1999). Multicellular tumor spheroids: intermediates between monolayer culture and in vivo tumor. Cell Biology International, 23: 157-161.
    • (1999) Cell Biology International , vol.23 , pp. 157-161
    • Kunz-Shughart, L.A.1
  • 18
    • 0036498496 scopus 로고    scopus 로고
    • Of layers and spheres: The reaggregate approach in tissue engineering
    • Layer PG, Robitzki A, Rothermel A et al. (2002). Of layers and spheres: the reaggregate approach in tissue engineering. Trends in Neurosciences, 25: 131-134.
    • (2002) Trends in Neurosciences , vol.25 , pp. 131-134
    • Layer, P.G.1    Robitzki, A.2    Rothermel, A.3
  • 19
    • 1642385430 scopus 로고    scopus 로고
    • Microscale tissue engineering using gravity-enforced cell assembly
    • Kelm JM & Fussenegger M (2004). Microscale tissue engineering using gravity-enforced cell assembly. Trends in Biotechnology, 22: 195-202.
    • (2004) Trends in Biotechnology , vol.22 , pp. 195-202
    • Kelm, J.M.1    Fussenegger, M.2
  • 20
    • 0035964349 scopus 로고    scopus 로고
    • Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
    • Brabletz T, Jung A, Reu S et al. (2001). Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proceedings of the National Academy of Sciences, USA, 98: 10356-10361.
    • (2001) Proceedings of the National Academy of Sciences, USA , vol.98 , pp. 10356-10361
    • Brabletz, T.1    Jung, A.2    Reu, S.3
  • 21
    • 0032583125 scopus 로고    scopus 로고
    • Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation
    • Korf T & Augustin HG (1998). Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation. Journal of Cell Biology, 143: 1341-1352.
    • (1998) Journal of Cell Biology , vol.143 , pp. 1341-1352
    • Korf, T.1    Augustin, H.G.2
  • 22
    • 0035121532 scopus 로고    scopus 로고
    • Blood vessel maturation in a 3-dimensional spheroidal coculture model: Direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness
    • Korf T, Kimmina S, Martiny-Baron G et al. (2001). Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness. FASEB Journal, 15: 447-457.
    • (2001) FASEB Journal , vol.15 , pp. 447-457
    • Korf, T.1    Kimmina, S.2    Martiny-Baron, G.3
  • 23
    • 6044224987 scopus 로고    scopus 로고
    • Bi-directional cell contact-dependent regulation of gene expression between endothelial cells and osteoblasts in a three-dimensional spheroidal coculture model
    • Stahl A, Wenger A, Weber H et al. (2004). Bi-directional cell contact-dependent regulation of gene expression between endothelial cells and osteoblasts in a three-dimensional spheroidal coculture model. Biochemical and Biophysical Research Communications, 322: 684-692.
    • (2004) Biochemical and Biophysical Research Communications , vol.322 , pp. 684-692
    • Stahl, A.1    Wenger, A.2    Weber, H.3
  • 24
    • 8544254739 scopus 로고    scopus 로고
    • Hanging-drop multicellular spheroids as a model of tumour angiogenesis
    • Timmins NE, Dietmair S & Nielsen LK (2004). Hanging-drop multicellular spheroids as a model of tumour angiogenesis. Angiogenesis, 7: 97-103.
    • (2004) Angiogenesis , vol.7 , pp. 97-103
    • Timmins, N.E.1    Dietmair, S.2    Nielsen, L.K.3
  • 25
    • 0017106277 scopus 로고
    • The hematopoietic microenvironment of the bone marrow: An ultrastructural study of the stroma in rats
    • Weiss L (1976). The hematopoietic microenvironment of the bone marrow: an ultrastructural study of the stroma in rats. Anatomical Record, 186: 161-184.
    • (1976) Anatomical Record , vol.186 , pp. 161-184
    • Weiss, L.1
  • 27
    • 0021364886 scopus 로고
    • A model of intramedullary hematopoietic microenvironments based on stereologic study of the distribution of endocloned marrow colonies
    • Lambertsen RH & Weiss L (1984). A model of intramedullary hematopoietic microenvironments based on stereologic study of the distribution of endocloned marrow colonies. Blood, 63: 287-297.
    • (1984) Blood , vol.63 , pp. 287-297
    • Lambertsen, R.H.1    Weiss, L.2
  • 28
    • 0017834345 scopus 로고
    • Endosteal marrow: A rich source of hematopoietic stem cells
    • Gong JK (1978). Endosteal marrow: a rich source of hematopoietic stem cells. Science, 199: 1443-1445.
    • (1978) Science , vol.199 , pp. 1443-1445
    • Gong, J.K.1
  • 29
    • 0035871882 scopus 로고    scopus 로고
    • Spatial localization of transplanted hematopoietic stem cells: Inferences for the localization of stem cell niches
    • Nilsson SK, Johnston HM & Coverdale JA (2001). Spatial localization of transplanted hematopoietic stem cells: inferences for the localization of stem cell niches. Blood, 97: 2293-2299.
    • (2001) Blood , vol.97 , pp. 2293-2299
    • Nilsson, S.K.1    Johnston, H.M.2    Coverdale, J.A.3
  • 30
    • 0242268524 scopus 로고    scopus 로고
    • Osteoblastic cells regulate the hematopoietic stem cell niche
    • Calvi LM, Adams GB, Welbrecht KW et al. (2003). Osteoblastic cells regulate the hematopoietic stem cell niche. Nature, 425: 841-846.
    • (2003) Nature , vol.425 , pp. 841-846
    • Calvi, L.M.1    Adams, G.B.2    Welbrecht, K.W.3
  • 31
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L et al. (2003). Identification of the haematopoietic stem cell niche and control of the niche size. Nature, 425: 836-841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3
  • 32
    • 12944297741 scopus 로고    scopus 로고
    • Bone marrow subendosteal microenvironment harbours functionally distinct haemosupportive stromal cell populations
    • Balduino A, Hurtado SP, Frazão P et al. (2005). Bone marrow subendosteal microenvironment harbours functionally distinct haemosupportive stromal cell populations. Cell and Tissue Research, 319: 255-266.
    • (2005) Cell and Tissue Research , vol.319 , pp. 255-266
    • Balduino, A.1    Hurtado, S.P.2    Frazão, P.3
  • 33
    • 0025224787 scopus 로고
    • Microenvironment organization and stromal cell associations of B lymphocyte precursor cells in mouse bone marrow
    • Jacobsen K & Osmond DG (1990). Microenvironment organization and stromal cell associations of B lymphocyte precursor cells in mouse bone marrow. European Journal of Immunology, 20: 2395-2404.
    • (1990) European Journal of Immunology , vol.20 , pp. 2395-2404
    • Jacobsen, K.1    Osmond, D.G.2
  • 34
    • 2942523585 scopus 로고    scopus 로고
    • Cellular niches controlling B lymphocyte behavior within bone marrow during development
    • Tokoyoda K, Egawa T, Sugiyama T et al. (2004). Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity, 20: 707-718.
    • (2004) Immunity , vol.20 , pp. 707-718
    • Tokoyoda, K.1    Egawa, T.2    Sugiyama, T.3
  • 35
    • 0035976526 scopus 로고    scopus 로고
    • Physiological migration of hematopoietic stem and progenitor cells
    • Wright DE, Wagers AJ, Gulati AP et al. (2001). Physiological migration of hematopoietic stem and progenitor cells. Science, 294: 1933-1935.
    • (2001) Science , vol.294 , pp. 1933-1935
    • Wright, D.E.1    Wagers, A.J.2    Gulati, A.P.3
  • 36
    • 0035991663 scopus 로고    scopus 로고
    • Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo
    • Askenazy N, Zorina T, Farkas DL et al. (2002). Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo. Stem Cells, 20: 301-310.
    • (2002) Stem Cells , vol.20 , pp. 301-310
    • Askenazy, N.1    Zorina, T.2    Farkas, D.L.3
  • 37
    • 0036754547 scopus 로고    scopus 로고
    • Current understanding of stem cell mobilization: The roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells
    • Lapidot T & Petit I (2002). Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Experimental Hematology, 30: 973-981.
    • (2002) Experimental Hematology , vol.30 , pp. 973-981
    • Lapidot, T.1    Petit, I.2
  • 38
    • 1442357036 scopus 로고    scopus 로고
    • Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization
    • Papayannopoulo T (2004). Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization. Blood, 103: 1580-1585.
    • (2004) Blood , vol.103 , pp. 1580-1585
    • Papayannopoulo, T.1
  • 40
    • 0035469853 scopus 로고    scopus 로고
    • Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor
    • Lévesque JP, Takamatsu Y, Nilsson SK et al. (2001). Vascular cell adhesion molecule-1 (CD106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor. Blood, 98: 1289-1297.
    • (2001) Blood , vol.98 , pp. 1289-1297
    • Lévesque, J.P.1    Takamatsu, Y.2    Nilsson, S.K.3
  • 42
    • 0029758113 scopus 로고    scopus 로고
    • Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
    • Nagasawa T, Hirota S, Tachibana K et al. (1996). Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature, 382: 635-638.
    • (1996) Nature , vol.382 , pp. 635-638
    • Nagasawa, T.1    Hirota, S.2    Tachibana, K.3
  • 43
    • 0033524834 scopus 로고    scopus 로고
    • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
    • Peled A, Petit I, Kollet O et al. (1999). Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science, 283: 845-848.
    • (1999) Science , vol.283 , pp. 845-848
    • Peled, A.1    Petit, I.2    Kollet, O.3
  • 44
    • 0035383801 scopus 로고    scopus 로고
    • Plasma elevation of stromall cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells
    • Hattori K, Heissig B, Tashiro K et al. (2001). Plasma elevation of stromall cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood, 97: 3354-3360.
    • (2001) Blood , vol.97 , pp. 3354-3360
    • Hattori, K.1    Heissig, B.2    Tashiro, K.3
  • 45
    • 0036302147 scopus 로고    scopus 로고
    • G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
    • Petit I, Szyper-Kravitz M, Nagler A et al. (2002). G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nature Immunology, 3: 687-694.
    • (2002) Nature Immunology , vol.3 , pp. 687-694
    • Petit, I.1    Szyper-Kravitz, M.2    Nagler, A.3
  • 46
    • 0032212144 scopus 로고    scopus 로고
    • Osteoclast-mediated bone resorption is stimulated during short-term administration of granulocyte colony-stimulating factor but is not responsible for hematopoietic progenitor cell mobilization
    • Takamatsu Y, Simmons PJ, Moore RJ et al. (1998). Osteoclast-mediated bone resorption is stimulated during short-term administration of granulocyte colony-stimulating factor but is not responsible for hematopoietic progenitor cell mobilization. Blood, 92: 3465-3473.
    • (1998) Blood , vol.92 , pp. 3465-3473
    • Takamatsu, Y.1    Simmons, P.J.2    Moore, R.J.3
  • 47
    • 0035826843 scopus 로고    scopus 로고
    • Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization
    • Yang F-C, Atkinson SJ, Gu Y et al. (2001). Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization. Proceedings of the National Academy of Sciences, USA, 98: 5614-5618.
    • (2001) Proceedings of the National Academy of Sciences USA , vol.98 , pp. 5614-5618
    • Yang, F.-C.1    Atkinson, S.J.2    Gu, Y.3
  • 48
    • 0142084736 scopus 로고    scopus 로고
    • Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases
    • Gu Y, Filippi M-D, Cancelas JA et al. (2003). Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases. Science, 302: 445-449.
    • (2003) Science , vol.302 , pp. 445-449
    • Gu, Y.1    Filippi, M.-D.2    Cancelas, J.A.3
  • 49
    • 0035166327 scopus 로고    scopus 로고
    • Dual role of H-Ras in regulation of lymphocyte function antigen-1 activity by stromal cell-derived factor 1α: Implications for leukocyte transmigration
    • Weber KSC, Ostermann G, Zernecke A et al. (2001). Dual role of H-Ras in regulation of lymphocyte function antigen-1 activity by stromal cell-derived factor 1α: implications for leukocyte transmigration. Molecular Biology of the Cell, 12: 3074-3086.
    • (2001) Molecular Biology of the Cell , vol.12 , pp. 3074-3086
    • Weber, K.S.C.1    Ostermann, G.2    Zernecke, A.3
  • 50
    • 0242437903 scopus 로고    scopus 로고
    • SDF-1α-induced intracellular calcium transient involves Rho GTPase signalling and is required for migration of hematopoietic progenitor cells
    • Henschler R, Riper A, Bistrian R et al. (2003). SDF-1α-induced intracellular calcium transient involves Rho GTPase signalling and is required for migration of hematopoietic progenitor cells. Biochemical and Biophysical Research Communications, 311: 1067-1071.
    • (2003) Biochemical and Biophysical Research Communications , vol.311 , pp. 1067-1071
    • Henschler, R.1    Riper, A.2    Bistrian, R.3
  • 51
    • 4344582910 scopus 로고    scopus 로고
    • Evaluation of mineralized collagen and alpha-tricalcium phosphate as scaffolds for tissue engineering of bone using human mesenchymal stem cells
    • Niemeyer P, Krause U, Fellenberg J et al. (2004). Evaluation of mineralized collagen and alpha-tricalcium phosphate as scaffolds for tissue engineering of bone using human mesenchymal stem cells. Cells Tissues Organs, 177: 68-78.
    • (2004) Cells Tissues Organs , vol.177 , pp. 68-78
    • Niemeyer, P.1    Krause, U.2    Fellenberg, J.3
  • 52
    • 4544311662 scopus 로고    scopus 로고
    • Biomimetic collagen scaffolds for human bone cell growth and differentiation
    • Yang XB, Bhatnagar RS & Oreffo RO (2004). Biomimetic collagen scaffolds for human bone cell growth and differentiation. Tissue Engineering, 10: 1148-1159.
    • (2004) Tissue Engineering , vol.10 , pp. 1148-1159
    • Yang, X.B.1    Bhatnagar, R.S.2    Oreffo, R.O.3
  • 53
    • 0031817577 scopus 로고    scopus 로고
    • In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells
    • Johnstone B, Hering TM, Caplan AI et al. (1998). In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Experimental Cell Research, 238: 265-272.
    • (1998) Experimental Cell Research , vol.238 , pp. 265-272
    • Johnstone, B.1    Hering, T.M.2    Caplan, A.I.3
  • 54
    • 0037007146 scopus 로고    scopus 로고
    • In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis
    • Sekiya I, Vuoristo JT, Larson BL et al. (2001). In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proceedings of the National Academy of Sciences, USA, 99: 4397-4402.
    • (2001) Proceedings of the National Academy of Sciences, USA , vol.99 , pp. 4397-4402
    • Sekiya, I.1    Vuoristo, J.T.2    Larson, B.L.3
  • 55
    • 0042671274 scopus 로고    scopus 로고
    • Formation of a chondro-osseous rudiment in micromass cultures of human bone-marrow stromal cells
    • Muraglia A, Corsi A, Riminucci M et al. (2003). Formation of a chondro-osseous rudiment in micromass cultures of human bone-marrow stromal cells. Journal of Cell Science, 116: 2949-2955.
    • (2003) Journal of Cell Science , vol.116 , pp. 2949-2955
    • Muraglia, A.1    Corsi, A.2    Riminucci, M.3
  • 56
    • 0036826739 scopus 로고    scopus 로고
    • Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells
    • Bug G, Rossmanith T, Henschler R et al. (2002). Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells. Journal of Leukocyte Biology, 72: 837-845.
    • (2002) Journal of Leukocyte Biology , vol.72 , pp. 837-845
    • Bug, G.1    Rossmanith, T.2    Henschler, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.