메뉴 건너뛰기




Volumn 14, Issue 16, 2005, Pages 2289-2303

Up-regulation of the ubiquitous alternative splicing factor Tra2β causes inclusion of a germ cell-specific exon

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GREEN FLUORESCENT PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HYBRID PROTEIN; MESSENGER RNA PRECURSOR; PROTEIN KINASE; PROTEIN P40; PROTEIN TRA2BETA; PURINE; RNA; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 26444575502     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi233     Document Type: Article
Times cited : (50)

References (92)
  • 1
    • 19944365069 scopus 로고    scopus 로고
    • Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform
    • Pan, Q., Shai, O., Misquitta, C., Zhang, W., Saltzman, A.L., Mohammad, N., Babak, T., Siu, H., Hughes, T.R., Morris, Q.D. [i#et al.#1i] (2004) Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform. [i#Mol. Cell#1i], [b#16#1b], 929-941.
    • (2004) Mol. Cell , vol.16 , pp. 929-941
    • Pan, Q.1    Shai, O.2    Misquitta, C.3    Zhang, W.4    Saltzman, A.L.5    Mohammad, N.6    Babak, T.7    Siu, H.8    Hughes, T.R.9    Morris, Q.D.10
  • 2
    • 0034256020 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing: The logic of combinatorial control
    • Smith, C.W. and Valcarcel, J. (2000) Alternative pre-mRNA splicing: The logic of combinatorial control. [i#Trends Biochem. Sci.#1i], [b#25#1b], 381-388.
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 381-388
    • Smith, C.W.1    Valcarcel, J.2
  • 3
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • Black, D.L. (2003) Mechanisms of alternative pre-messenger RNA splicing. [i#Annu. Rev. Biochem.#1i], [b#72#1b], 291-336.
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 291-336
    • Black, D.L.1
  • 4
    • 8644278829 scopus 로고    scopus 로고
    • Identification of alternative splicing regulators by RNA interference in Drosophila
    • Park, J.W., Parisky, K., Celotto, A.M., Reenan, R.A. and Graveley, B.R. (2004) Identification of alternative splicing regulators by RNA interference in [i#Drosophila. Proc. Natl Acad. Sci. USA#1i], [b#101#1b], 15974-15979.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 15974-15979
    • Park, J.W.1    Parisky, K.2    Celotto, A.M.3    Reenan, R.A.4    Graveley, B.R.5
  • 5
    • 10944229314 scopus 로고    scopus 로고
    • Variation in alternative splicing across human tissues
    • Yeo, G., Holste, D., Kreiman, G. and Burge, C.B. (2004) Variation in alternative splicing across human tissues. [i#Genome Biol.#1i], [b#5#1b], R74.
    • (2004) Genome Biol. , vol.5
    • Yeo, G.1    Holste, D.2    Kreiman, G.3    Burge, C.B.4
  • 7
    • 1042266636 scopus 로고    scopus 로고
    • Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: Phosphorylation by DYRK1A and colocalization with splicing factors
    • de Graaf, K., Hekerman, P., Spelten, O., Herrmann, A., Packman, L.C., Bussow, K., Muller-Newen, G. and Becker, W. (2004) Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors. [i#J. Biol. Chem.#1i], [b#279#1b], 4612-4624.
    • (2004) J. Biol. Chem. , vol.279 , pp. 4612-4624
    • de Graaf, K.1    Hekerman, P.2    Spelten, O.3    Herrmann, A.4    Packman, L.C.5    Bussow, K.6    Muller-Newen, G.7    Becker, W.8
  • 8
    • 0036777902 scopus 로고    scopus 로고
    • Alternative splicing in the testes
    • Venables, J.P. (2002) Alternative splicing in the testes. [i#Curr. Opin. Genet. Dev.#1i], [b#12#1b], 615-619.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 615-619
    • Venables, J.P.1
  • 10
    • 0024299506 scopus 로고
    • Effects of RNA secondary structure on alternative splicing of pre-mRNA: Is folding limited to a region behind the transcribing RNA polymerase?
    • Eperon, L.P., Graham, I.R., Griffiths, A.D. and Eperon, I.C. (1988) Effects of RNA secondary structure on alternative splicing of pre-mRNA: is folding limited to a region behind the transcribing RNA polymerase? [i#Cell#1i], [b#54#1b], 393-401.
    • (1988) Cell , vol.54 , pp. 393-401
    • Eperon, L.P.1    Graham, I.R.2    Griffiths, A.D.3    Eperon, I.C.4
  • 11
    • 0032534537 scopus 로고    scopus 로고
    • Co-transcriptional commitment to alternative splice site selection
    • Roberts, G.C., Gooding, C., Mak, H.Y., Proudfoot, N.J. and Smith, C.W. (1998) Co-transcriptional commitment to alternative splice site selection. [i#Nucleic Acids Res.#1i], [b#26#1b], 5568-5572.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 5568-5572
    • Roberts, G.C.1    Gooding, C.2    Mak, H.Y.3    Proudfoot, N.J.4    Smith, C.W.5
  • 12
    • 10044274340 scopus 로고    scopus 로고
    • Influence of RNA secondary structure on the pre-mRNA splicing process
    • Buratti, E. and Baralle, F.E. (2004) Influence of RNA secondary structure on the pre-mRNA splicing process. [i#Mol. Cell. Biol.#1i], [b#24#1b], 10505-10514.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 10505-10514
    • Buratti, E.1    Baralle, F.E.2
  • 13
    • 17044427579 scopus 로고    scopus 로고
    • From the cover: Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers
    • Ibrahim el, C., Schaal, T.D., Hertel, K.J., Reed, R. and Maniatis, T. (2005) From the cover: Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers. [i#Proc. Natl Acad. Sci. USA#1i], [b#102#1b], 5002-5007.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5002-5007
    • Ibrahim el, C.1    Schaal, T.D.2    Hertel, K.J.3    Reed, R.4    Maniatis, T.5
  • 14
  • 15
    • 2142716979 scopus 로고    scopus 로고
    • The link between mRNA processing and transcription: Communication works both ways
    • Zorio, D.A. and Bentley, D.L. (2004) The link between mRNA processing and transcription: Communication works both ways. [i#Exp. Cell Res.#1i], [b#296#1b], 91-97.
    • (2004) Exp. Cell Res. , vol.296 , pp. 91-97
    • Zorio, D.A.1    Bentley, D.L.2
  • 16
    • 0033834946 scopus 로고    scopus 로고
    • Coupled in vitro synthesis and splicing of RNA polymerase II transcripts
    • Ghosh, S. and Garcia-Blanco, M.A. (2000) Coupled [i#in vitro#1i] synthesis and splicing of RNA polymerase II transcripts. [i#RNA#1i], [b#6#1b] 1325-1334.
    • (2000) RNA , vol.6 , pp. 1325-1334
    • Ghosh, S.1    Garcia-Blanco, M.A.2
  • 17
    • 14644431487 scopus 로고    scopus 로고
    • Broad specificity of SR (serine/arginine) proteins in the regulation of alternative splicing of pre-messenger RNA
    • Bourgeois, C.F., Lejeune, F. and Stevenin, J. (2004) Broad specificity of SR (serine/arginine) proteins in the regulation of alternative splicing of pre-messenger RNA. [i#Prog. Nucleic Acid Res. Mol. Biol.#1i], [b#78#1b], 37-88.
    • (2004) Prog. Nucleic Acid Res. Mol. Biol. , vol.78 , pp. 37-88
    • Bourgeois, C.F.1    Lejeune, F.2    Stevenin, J.3
  • 18
    • 1842693352 scopus 로고    scopus 로고
    • Multiple roles of the SR protein family in splicing regulation
    • Sanford, J.R., Longman, D. and Caceres, J.F. (2003) Multiple roles of the SR protein family in splicing regulation. [i#Prog. Mol. Subcell. Biol.#1i], [b#31#1b], 33-58.
    • (2003) Prog. Mol. Subcell. Biol. , vol.31 , pp. 33-58
    • Sanford, J.R.1    Longman, D.2    Caceres, J.F.3
  • 19
    • 14644445227 scopus 로고    scopus 로고
    • SRprises along a messenger's journey
    • Huang, Y. and Steitz, J.A. (2005) SRprises along a messenger's journey. [i#Mol. Cell#1i], [b#17#1b], 613-615.
    • (2005) Mol. Cell , vol.17 , pp. 613-615
    • Huang, Y.1    Steitz, J.A.2
  • 20
    • 14744290800 scopus 로고    scopus 로고
    • RS domains contact the pre-mRNA throughout spliceosome assembly
    • Hertel, K.J. and Graveley, B.R. (2005) RS domains contact the pre-mRNA throughout spliceosome assembly. [i#Trends Biochem. Sci.#1i], [b#30#1b], 115-118.
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 115-118
    • Hertel, K.J.1    Graveley, B.R.2
  • 21
    • 0034701246 scopus 로고    scopus 로고
    • RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing
    • Venables, J.P., Elliott, D.J., Makarova, O.V., Makarov, E.M., Cooke, H.J. and Eperon, I.C. (2000) RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing. [i#Hum. Mol. Genet.#1i], [b#9#1b], 685-694.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 685-694
    • Venables, J.P.1    Elliott, D.J.2    Makarova, O.V.3    Makarov, E.M.4    Cooke, H.J.5    Eperon, I.C.6
  • 22
    • 1542613791 scopus 로고    scopus 로고
    • PCR isolation and cloning of novel splice variant mRNAs from known drug target genes
    • Jin, P., Fu, G.K., Wilson, A.D., Yang, J., Chien, D., Hawkins, P.R., Au-Young, J. and Stuve, L.L. (2004) PCR isolation and cloning of novel splice variant mRNAs from known drug target genes. [i#Genomics#1i], [b#83#1b] 566-571.
    • (2004) Genomics , vol.83 , pp. 566-571
    • Jin, P.1    Fu, G.K.2    Wilson, A.D.3    Yang, J.4    Chien, D.5    Hawkins, P.R.6    Au-Young, J.7    Stuve, L.L.8
  • 23
    • 2942655154 scopus 로고    scopus 로고
    • Differential expression of thyroperoxidase mRNA splice variants in human thyroid tumors
    • Le Fourn, V., Ferrand, M. and Franc, J.L. (2004) Differential expression of thyroperoxidase mRNA splice variants in human thyroid tumors. [i#Biochim. Biophys. Acta#1i], [b#1689#1b], 134-141.
    • (2004) Biochim. Biophys. Acta , vol.1689 , pp. 134-141
    • Le Fourn, V.1    Ferrand, M.2    Franc, J.L.3
  • 24
    • 1642473041 scopus 로고    scopus 로고
    • How prevalent is functional alternative splicing in the human genome?
    • Sorek, R., Shamir, R. and Ast, G. (2004) How prevalent is functional alternative splicing in the human genome? [i#Trends Genet.#1i], [b#20#1b], 68-71.
    • (2004) Trends Genet. , vol.20 , pp. 68-71
    • Sorek, R.1    Shamir, R.2    Ast, G.3
  • 28
    • 0033521126 scopus 로고    scopus 로고
    • Distinct factor requirements for exonic splicing enhancer function and binding of U2AF to the polypyrimidine tract
    • Li, Y. and Blencowe, B.J. (1999) Distinct factor requirements for exonic splicing enhancer function and binding of U2AF to the polypyrimidine tract. [i#J. Biol. Chem.#1i], [b#274#1b], 35074-35079.
    • (1999) J. Biol. Chem. , vol.274 , pp. 35074-35079
    • Li, Y.1    Blencowe, B.J.2
  • 29
    • 0032478506 scopus 로고    scopus 로고
    • Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing
    • Tacke, R., Tohyama, M., Ogawa, S. and Manley, J.L. (1998) Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing. [i#Cell#1i] [b#93#1b], 139-148.
    • (1998) Cell , vol.93 , pp. 139-148
    • Tacke, R.1    Tohyama, M.2    Ogawa, S.3    Manley, J.L.4
  • 30
    • 0037047644 scopus 로고    scopus 로고
    • Predictive identification of exonic splicing enhancers in human genes
    • Fairbrother, W.G., Yeh, R.F., Sharp, P.A. and Burge, C.B. (2002) Predictive identification of exonic splicing enhancers in human genes. [i#Science#1i], [b#297#1b], 1007-1013.
    • (2002) Science , vol.297 , pp. 1007-1013
    • Fairbrother, W.G.1    Yeh, R.F.2    Sharp, P.A.3    Burge, C.B.4
  • 31
    • 0033017499 scopus 로고    scopus 로고
    • The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers
    • Cavaloc, Y., Bourgeois, C.F., Kister, L. and Stevenin, J. (1999) The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers. [i#RNA#1i], [b#5#1b], 468-483.
    • (1999) RNA , vol.5 , pp. 468-483
    • Cavaloc, Y.1    Bourgeois, C.F.2    Kister, L.3    Stevenin, J.4
  • 32
    • 0028129989 scopus 로고
    • Conserved structures and diversity of functions of RNA-binding proteins
    • Burd, C.G. and Dreyfuss, G. (1994) Conserved structures and diversity of functions of RNA-binding proteins. [i#Science#1i], [b#265#1b], 615-621.
    • (1994) Science , vol.265 , pp. 615-621
    • Burd, C.G.1    Dreyfuss, G.2
  • 33
    • 0041665176 scopus 로고    scopus 로고
    • A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy
    • Kashima, T. and Manley, J.L. (2003) A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy. [i#Nat. Genet.#1i], [b#34#1b] 460-463.
    • (2003) Nat. Genet. , vol.34 , pp. 460-463
    • Kashima, T.1    Manley, J.L.2
  • 34
    • 0035941211 scopus 로고    scopus 로고
    • Determination of the RNA binding specificity of the heterogeneous nuclear ribonucleoprotein (hnRNP) H/H′/F/2H9 family
    • Caputi, M. and Zahler, A.M. (2001) Determination of the RNA binding specificity of the heterogeneous nuclear ribonucleoprotein (hnRNP) H/ H′/F/2H9 family. [i#J. Biol. Chem.#1i], [b#276#1b], 43850-43859.
    • (2001) J. Biol. Chem. , vol.276 , pp. 43850-43859
    • Caputi, M.1    Zahler, A.M.2
  • 35
    • 4644256654 scopus 로고    scopus 로고
    • hnRNP A1 and the SR proteins ASF/SF2 and SC35 have antagonistic functions in splicing of beta-tropomyosin exon 6B
    • Expert-Bezancon, A., Sureau, A., Durosay, P., Salesse, R., Groeneveld, H., Lecaer, J.P. and Marie, J. (2004) hnRNP A1 and the SR proteins ASF/ SF2 and SC35 have antagonistic functions in splicing of beta-tropomyosin exon 6B. [i#J. Biol. Chem.#1i], [b#279#1b], 38249-38259.
    • (2004) J. Biol. Chem. , vol.279 , pp. 38249-38259
    • Expert-Bezancon, A.1    Sureau, A.2    Durosay, P.3    Salesse, R.4    Groeneveld, H.5    Lecaer, J.P.6    Marie, J.7
  • 36
    • 0037372109 scopus 로고    scopus 로고
    • Roles for SR proteins and hnRNP A1 in the regulation of c-src exon N1
    • Rooke, N., Markovtsov, V., Cagavi, E. and Black, D.L. (2003) Roles for SR proteins and hnRNP A1 in the regulation of c-src exon N1. [i#Mol. Cell. Biol.#1i], [b#23#1b], 1874-1884.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1874-1884
    • Rooke, N.1    Markovtsov, V.2    Cagavi, E.3    Black, D.L.4
  • 37
    • 0036974666 scopus 로고    scopus 로고
    • A Janus splicing regulatory element modulates HIV-1 tat and rev mRNA production by coordination of hnRNP A1 cooperative binding
    • Marchand, V., Mereau, A., Jacquenet, S., Thomas, D., Mougin, A., Gattoni, R., Stevenin, J. and Branlant, C. (2002) A Janus splicing regulatory element modulates HIV-1 tat and rev mRNA production by coordination of hnRNP A1 cooperative binding. [i#J. Mol. Biol.#1i], [b#323#1b], 629-652.
    • (2002) J. Mol. Biol. , vol.323 , pp. 629-652
    • Marchand, V.1    Mereau, A.2    Jacquenet, S.3    Thomas, D.4    Mougin, A.5    Gattoni, R.6    Stevenin, J.7    Branlant, C.8
  • 38
    • 0033762534 scopus 로고    scopus 로고
    • Selection of alternative 5′ splice sites: Role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1
    • Eperon, I.C., Makarova, O.V., Mayeda, A., Munroe, S.H., Caceres, J.F., Hayward, D.G. and Krainer, A.R. (2000) Selection of alternative 5′ splice sites: Role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1. [i#Mol. Cell. Biol.#1i], [b#20#1b], 8303-8318.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8303-8318
    • Eperon, I.C.1    Makarova, O.V.2    Mayeda, A.3    Munroe, S.H.4    Caceres, J.F.5    Hayward, D.G.6    Krainer, A.R.7
  • 39
    • 0032740121 scopus 로고    scopus 로고
    • Identification of a bidirectional splicing enhancer: Differential involvement of SR proteins in 5′ or 3′ splice site activation
    • Bourgeois, C.F., Popielarz, M., Hildwein, G. and Stevenin, J. (1999) Identification of a bidirectional splicing enhancer: Differential involvement of SR proteins in 5′ or 3′ splice site activation. [i#Mol. Cell. Biol.#1i], [b#19#1b], 7347-7356.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7347-7356
    • Bourgeois, C.F.1    Popielarz, M.2    Hildwein, G.3    Stevenin, J.4
  • 40
    • 0031010564 scopus 로고    scopus 로고
    • Molecular cloning of htra2-beta-1 and htra2-beta-2, two human homologs of tra-2 generated by alternative splicing
    • Beil, B., Screaton, G. and Stamm, S. (1997) Molecular cloning of htra2-beta-1 and htra2-beta-2, two human homologs of tra-2 generated by alternative splicing. [i#DNA Cell Biol.#1i], [b#16#1b], 679-690.
    • (1997) DNA Cell Biol. , vol.16 , pp. 679-690
    • Beil, B.1    Screaton, G.2    Stamm, S.3
  • 41
    • 0038512304 scopus 로고    scopus 로고
    • Expression of Tra2beta isoforms is developmentally regulated in a tissue- and temporal-specific pattern
    • Chen, X., Guo, L., Lin, W. and Xu, P. (2003) Expression of Tra2beta isoforms is developmentally regulated in a tissue- and temporal-specific pattern. [i#Cell Biol. Int.#1i], [b#27#1b], 491-496.
    • (2003) Cell Biol. Int. , vol.27 , pp. 491-496
    • Chen, X.1    Guo, L.2    Lin, W.3    Xu, P.4
  • 42
    • 17144453865 scopus 로고    scopus 로고
    • Human transformer-2-beta gene (SFRS10): Complete nucleotide sequence, chromosomal localization, and generation of a tissue-specific isoform
    • Nayler, O., Cap, C. and Stamm, S. (1998) Human transformer-2-beta gene (SFRS10): Complete nucleotide sequence, chromosomal localization, and generation of a tissue-specific isoform. [i#Genomics#1i], [b#53#1b], 191-202.
    • (1998) Genomics , vol.53 , pp. 191-202
    • Nayler, O.1    Cap, C.2    Stamm, S.3
  • 43
    • 0742323558 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics
    • Maquat, L.E. (2004) Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics. [i#Nat. Rev. Mol. Cell Biol.#1i], [b#5#1b], 89-99.
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 89-99
    • Maquat, L.E.1
  • 45
    • 0345898928 scopus 로고    scopus 로고
    • Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors
    • Kim, Y.H., Choi, C.Y., Lee, S.J., Conti, M.A. and Kim, Y. (1998) Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. [i#J. Biol. Chem.#1i], [b#273#1b], 25875-25879.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25875-25879
    • Kim, Y.H.1    Choi, C.Y.2    Lee, S.J.3    Conti, M.A.4    Kim, Y.5
  • 46
    • 0037443035 scopus 로고    scopus 로고
    • Pre-mRNA splicing and human disease
    • Faustino, N.A. and Cooper, T.A. (2003) Pre-mRNA splicing and human disease. [i#Genes Dev.#1i], [b#17#1b], 419-437.
    • (2003) Genes Dev. , vol.17 , pp. 419-437
    • Faustino, N.A.1    Cooper, T.A.2
  • 47
    • 17144427268 scopus 로고    scopus 로고
    • Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c.SRp55 complex that either recruits or antagonizes htra2beta1
    • Wang, Y., Wang, J., Gao, L., Lafyatis, R., Stamm, S. and Andreadis, A. (2005) Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c.SRp55 complex that either recruits or antagonizes htra2beta1. [i#J. Biol. Chem.#1i], [b#280#1b], 14230-14239.
    • (2005) J. Biol. Chem. , vol.280 , pp. 14230-14239
    • Wang, Y.1    Wang, J.2    Gao, L.3    Lafyatis, R.4    Stamm, S.5    Andreadis, A.6
  • 48
    • 0038819945 scopus 로고    scopus 로고
    • Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta
    • Jiang, Z., Tang, H., Havlioglu, N., Zhang, X., Stamm, S., Yan, R. and Wu, J.Y. (2003) Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta. [i#J. Biol. Chem.#1i], [b#278#1b], 18997-19007.
    • (2003) J. Biol. Chem. , vol.278 , pp. 18997-19007
    • Jiang, Z.1    Tang, H.2    Havlioglu, N.3    Zhang, X.4    Stamm, S.5    Yan, R.6    Wu, J.Y.7
  • 49
    • 0345801103 scopus 로고    scopus 로고
    • Phosphorylation-dependent control of the pre-mRNA splicing machinery
    • Soret, J. and Tazi, J. (2003) Phosphorylation-dependent control of the pre-mRNA splicing machinery. [i#Prog. Mol. Subcell. Biol.#1i], [b#31#1b], 89-126.
    • (2003) Prog. Mol. Subcell. Biol. , vol.31 , pp. 89-126
    • Soret, J.1    Tazi, J.2
  • 50
    • 1142310938 scopus 로고    scopus 로고
    • Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock
    • Shin, C., Feng, Y. and Manley, J.L. (2004) Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. [i#Nature#1i], [b#427#1b] 553-558.
    • (2004) Nature , vol.427 , pp. 553-558
    • Shin, C.1    Feng, Y.2    Manley, J.L.3
  • 51
    • 0032238550 scopus 로고    scopus 로고
    • Protein phosphorylation plays an essential role in the regulation of alternative splicing and sex determination in Drosophila
    • Du, C., McGuffin, M.E., Dauwalder, B., Rabinow, L. and Mattox, W. (1998) Protein phosphorylation plays an essential role in the regulation of alternative splicing and sex determination in [i#Drosophila. Mol. Cell#1i] [b#2#1b], 741-750.
    • (1998) Mol. Cell , vol.2 , pp. 741-750
    • Du, C.1    McGuffin, M.E.2    Dauwalder, B.3    Rabinow, L.4    Mattox, W.5
  • 52
    • 0038043222 scopus 로고    scopus 로고
    • Phosphorylation-dependent and -independent nuclear import of RS domain-containing splicing factors and regulators
    • Yun, C.Y., Velazquez-Dones, A.L., Lyman, S.K. and Fu, X.D. (2003) Phosphorylation-dependent and -independent nuclear import of RS domain-containing splicing factors and regulators. [i#J. Biol. Chem.#1i], [b#278#1b], 18050-18055.
    • (2003) J. Biol. Chem. , vol.278 , pp. 18050-18055
    • Yun, C.Y.1    Velazquez-Dones, A.L.2    Lyman, S.K.3    Fu, X.D.4
  • 53
    • 1542359466 scopus 로고    scopus 로고
    • Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA
    • Stoilov, P., Daoud, R., Nayler, O. and Stamm, S. (2004) Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA. [i#Hum. Mol. Genet.#1i], [b#13#1b], 509-524.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 509-524
    • Stoilov, P.1    Daoud, R.2    Nayler, O.3    Stamm, S.4
  • 54
    • 10944272640 scopus 로고    scopus 로고
    • Tau gene alternative splicing: Expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases
    • Andreadis, A. (2005) Tau gene alternative splicing: Expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases. [i#Biochim. Biophys. Acta.#1i], [b#1739#1b], 91-103.
    • (2005) Biochim. Biophys. Acta , vol.1739 , pp. 91-103
    • Andreadis, A.1
  • 55
    • 0037669004 scopus 로고    scopus 로고
    • HnRNP G and Tra2beta: Opposite effects on splicing matched by antagonism in RNA binding
    • Nasim, M.T., Chernova, T.K., Chowdhury, H.M., Yue, B.G. and Eperon, I.C. (2003) HnRNP G and Tra2beta: Opposite effects on splicing matched by antagonism in RNA binding. [i#Hum. Mol. Genet.#1i], [b#12#1b], 1337-1348.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1337-1348
    • Nasim, M.T.1    Chernova, T.K.2    Chowdhury, H.M.3    Yue, B.G.4    Eperon, I.C.5
  • 56
    • 0037101846 scopus 로고    scopus 로고
    • hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1
    • Hofmann, Y. and Wirth, B. (2002) hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1. [i#Hum. Mol. Genet.#1i], [b#11#1b], 2037-2049.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2037-2049
    • Hofmann, Y.1    Wirth, B.2
  • 57
    • 0034662922 scopus 로고    scopus 로고
    • Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2)
    • Hofmann, Y., Lorson, C.L., Stamm, S., Androphy, E.J. and Wirth, B. (2000) Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2). [i#Proc. Natl Acad. Sci. USA#1i], [b#97#1b], 9618-9623.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9618-9623
    • Hofmann, Y.1    Lorson, C.L.2    Stamm, S.3    Androphy, E.J.4    Wirth, B.5
  • 58
    • 3442894421 scopus 로고    scopus 로고
    • hnRNP H binding at the 5′ splice site correlates with the pathological effect of two intronic mutations in the NF-1 and TSHbeta genes
    • Buratti, E., Baralle, M., De Conti, L., Baralle, D., Romano, M., Ayala, Y.M. and Baralle, F.E. (2004) hnRNP H binding at the 5′ splice site correlates with the pathological effect of two intronic mutations in the NF-1 and TSHbeta genes. [i#Nucleic Acids Res.#1i], [b#32#1b], 4224-4236.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 4224-4236
    • Buratti, E.1    Baralle, M.2    De Conti, L.3    Baralle, D.4    Romano, M.5    Ayala, Y.M.6    Baralle, F.E.7
  • 59
    • 0032953308 scopus 로고    scopus 로고
    • hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells
    • Chou, M.Y., Rooke, N., Turck, C.W. and Black, D.L. (1999) hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. [i#Mol. Cell. Biol.#1i], [b#19#1b], 69-77.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 69-77
    • Chou, M.Y.1    Rooke, N.2    Turck, C.W.3    Black, D.L.4
  • 60
    • 10644254760 scopus 로고    scopus 로고
    • A molecular code for splicing silencing: Configurations of guanosine-rich motifs
    • Grabowski, P.J. (2004) A molecular code for splicing silencing: configurations of guanosine-rich motifs. [i#Biochem. Soc. Trans.#1i], [b#32#1b], 924-927.
    • (2004) Biochem. Soc. Trans. , vol.32 , pp. 924-927
    • Grabowski, P.J.1
  • 61
    • 1642372088 scopus 로고    scopus 로고
    • SC35 and heterogeneous nuclear ribonucleoprotein A/B proteins bind to a juxtaposed exonic splicing enhancer/exonic splicing silencer element to regulate HIV-1 tat exon 2 splicing
    • Zahler, A.M., Damgaard, C.K., Kjems, J. and Caputi, M. (2004) SC35 and heterogeneous nuclear ribonucleoprotein A/B proteins bind to a juxtaposed exonic splicing enhancer/exonic splicing silencer element to regulate HIV-1 tat exon 2 splicing. [i#J. Biol. Chem.#1i], [b#279#1b], 10077-10084.
    • (2004) J. Biol. Chem. , vol.279 , pp. 10077-10084
    • Zahler, A.M.1    Damgaard, C.K.2    Kjems, J.3    Caputi, M.4
  • 63
    • 0344074646 scopus 로고    scopus 로고
    • Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors
    • Hanamura, A., Caceres, J.F., Mayeda, A., Franza, B.R., Jr and Krainer, A.R. (1998) Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors. [i#RNA#1i], [b#4#1b], 430-444.
    • (1998) RNA , vol.4 , pp. 430-444
    • Hanamura, A.1    Caceres, J.F.2    Mayeda, A.3    Franza Jr., B.R.4    Krainer, A.R.5
  • 64
    • 0028881190 scopus 로고
    • Cell type-specific expression of hnRNP proteins
    • Kamma, H., Portman, D.S. and Dreyfuss, G. (1995) Cell type-specific expression of hnRNP proteins. [i#Exp. Cell Res.#1i], [b#221#1b], 187-196.
    • (1995) Exp. Cell Res. , vol.221 , pp. 187-196
    • Kamma, H.1    Portman, D.S.2    Dreyfuss, G.3
  • 65
    • 0034618495 scopus 로고    scopus 로고
    • Testis- and developmental stage-specific expression of hnRNP A2/B1 splicing isoforms, B0a/b
    • Matsui, M., Horiguchi, H., Kamma, H., Fujiwara, M., Ohtsubo, R. and Ogata, T. (2000) Testis- and developmental stage-specific expression of hnRNP A2/B1 splicing isoforms, B0a/b. [i#Biochim. Biophys. Acta#1i], [b#1493#1b], 33-40.
    • (2000) Biochim. Biophys. Acta , vol.1493 , pp. 33-40
    • Matsui, M.1    Horiguchi, H.2    Kamma, H.3    Fujiwara, M.4    Ohtsubo, R.5    Ogata, T.6
  • 66
    • 0031717887 scopus 로고    scopus 로고
    • Activation of androgen receptor function by a novel nuclear protein kinase
    • Moilanen, A.M., Karvonen, U., Poukka, H., Janne, O.A. and Palvimo, J.J. (1998) Activation of androgen receptor function by a novel nuclear protein kinase. [i#Mol. Biol. Cell#1i], [b#9#1b], 2527-2543.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 2527-2543
    • Moilanen, A.M.1    Karvonen, U.2    Poukka, H.3    Janne, O.A.4    Palvimo, J.J.5
  • 67
    • 0037627405 scopus 로고    scopus 로고
    • Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)
    • Kondo, S., Lu, Y., Debbas, M., Lin, A.W., Sarosi, I., Itie, A., Wakeham, A., Tuan, J., Saris, C., Elliott, G. [i#et al.#1i] (2003) Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). [i#Proc. Natl Acad. Sci. USA#1i], [b#100#1b], 5431-5436.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5431-5436
    • Kondo, S.1    Lu, Y.2    Debbas, M.3    Lin, A.W.4    Sarosi, I.5    Itie, A.6    Wakeham, A.7    Tuan, J.8    Saris, C.9    Elliott, G.10
  • 68
    • 0037200042 scopus 로고    scopus 로고
    • Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo
    • Kim, E.J., Park, J.S. and Um, S.J. (2002) Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family [i#in vivo. J. Biol. Chem.#1i], [b#277#1b], 32020-32028.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32020-32028
    • Kim, E.J.1    Park, J.S.2    Um, S.J.3
  • 69
    • 2442678753 scopus 로고    scopus 로고
    • PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains
    • Moller, A., Sirma, H., Hofmann, T.G., Rueffer, S., Klimczak, E., Droge, W., Will, H. and Schmitz, M.L. (2003) PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains. [i#Cancer Res.#1i], [b#63#1b], 4310-4314.
    • (2003) Cancer Res. , vol.63 , pp. 4310-4314
    • Moller, A.1    Sirma, H.2    Hofmann, T.G.3    Rueffer, S.4    Klimczak, E.5    Droge, W.6    Will, H.7    Schmitz, M.L.8
  • 70
    • 0030731040 scopus 로고    scopus 로고
    • Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1
    • Begley, D.A., Berkenpas, M.B., Sampson, K.E. and Abraham, I. (1997) Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1. [i#Gene#1i], [b#200#1b], 35-43.
    • (1997) Gene , vol.200 , pp. 35-43
    • Begley, D.A.1    Berkenpas, M.B.2    Sampson, K.E.3    Abraham, I.4
  • 71
    • 0034675849 scopus 로고    scopus 로고
    • FIST/HIPK3: A Fas/FADD-interacting serine/threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation
    • Rochat-Steiner, V., Becker, K., Micheau, O., Schneider, P., Burns, K. and Tschopp, J. (2000) FIST/HIPK3: A Fas/FADD-interacting serine/ threonine kinase that induces FADD phosphorylation and inhibits fas-mediated Jun NH(2)-terminal kinase activation. [i#J. Exp. Med.#1i], [b#192#1b], 1165-1174.
    • (2000) J. Exp. Med. , vol.192 , pp. 1165-1174
    • Rochat-Steiner, V.1    Becker, K.2    Micheau, O.3    Schneider, P.4    Burns, K.5    Tschopp, J.6
  • 72
    • 2342443733 scopus 로고    scopus 로고
    • JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells
    • Curtin, J.F. and Cotter, T.G. (2004) JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells. [i#J. Biol. Chem.#1i], [b#279#1b], 17090-17100.
    • (2004) J. Biol. Chem. , vol.279 , pp. 17090-17100
    • Curtin, J.F.1    Cotter, T.G.2
  • 73
    • 0035977067 scopus 로고    scopus 로고
    • FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1
    • Chalfant, C.E., Ogretmen, B., Galadari, S., Kroesen, B.J., Pettus, B.J. and Hannun, Y.A. (2001) FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1. [i#J. Biol. Chem.#1i], [b#276#1b], 44848-44855.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44848-44855
    • Chalfant, C.E.1    Ogretmen, B.2    Galadari, S.3    Kroesen, B.J.4    Pettus, B.J.5    Hannun, Y.A.6
  • 74
    • 0345239828 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing and regulation of programmed cell death
    • Wu, J.Y., Tang, H. and Havlioglu, N. (2003) Alternative pre-mRNA splicing and regulation of programmed cell death. [i#Prog. Mol. Subcell. Biol.#1i], [b#31#1b], 153-185.
    • (2003) Prog. Mol. Subcell. Biol. , vol.31 , pp. 153-185
    • Wu, J.Y.1    Tang, H.2    Havlioglu, N.3
  • 75
    • 10644270731 scopus 로고    scopus 로고
    • DYRK gene structure and erythroid-restricted features of DYRK3 gene expression
    • Zhang, D., Li, K., Erickson-Miller, C.L., Weiss, M. and Wojchowski, D.M. (2005) DYRK gene structure and erythroid-restricted features of DYRK3 gene expression. [i#Genomics#1i], [b#85#1b], 117-130.
    • (2005) Genomics , vol.85 , pp. 117-130
    • Zhang, D.1    Li, K.2    Erickson-Miller, C.L.3    Weiss, M.4    Wojchowski, D.M.5
  • 76
    • 1642540255 scopus 로고    scopus 로고
    • Human RNPS1 and its associated factors: A versatile alternative pre-mRNA splicing regulator in vivo
    • Sakashita, E., Tatsumi, S., Werner, D., Endo, H. and Mayeda, A. (2004) Human RNPS1 and its associated factors: A versatile alternative pre-mRNA splicing regulator [i#in vivo. Mol. Cell. Biol.#1i], [b#24#1b], 1174-1187.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 1174-1187
    • Sakashita, E.1    Tatsumi, S.2    Werner, D.3    Endo, H.4    Mayeda, A.5
  • 77
    • 0033009241 scopus 로고    scopus 로고
    • Activity-dependent regulation of alternative splicing patterns in the rat brain
    • Daoud, R., Da Penha Berzaghi, M., Siedler, F., Hubener, M. and Stamm, S. (1999) Activity-dependent regulation of alternative splicing patterns in the rat brain. [i#Eur. J. Neurosci.#1i], [b#11#1b], 788-802.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 788-802
    • Daoud, R.1    Da Penha Berzaghi, M.2    Siedler, F.3    Hubener, M.4    Stamm, S.5
  • 78
    • 0033565285 scopus 로고    scopus 로고
    • hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing
    • Caputi, M., Mayeda, A., Krainer, A.R. and Zahler, A.M. (1999) hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing. [i#EMBO J.#1i], [b#18#1b], 4060-4067.
    • (1999) EMBO J. , vol.18 , pp. 4060-4067
    • Caputi, M.1    Mayeda, A.2    Krainer, A.R.3    Zahler, A.M.4
  • 79
    • 0033838148 scopus 로고    scopus 로고
    • The RNA-binding protein TIA-1 is a novel mammalian splicing regulator acting through intron sequences adjacent to a 5′ splice site
    • Del Gatto-Konczak, F., Bourgeois, C.F., Le Guiner, C., Kister, L., Gesnel, M.C., Stevenin, J. and Breathnach, R. (2000) The RNA-binding protein TIA-1 is a novel mammalian splicing regulator acting through intron sequences adjacent to a 5′ splice site. [i#Mol. Cell. Biol.#1i], [b#20#1b], 6287-6299.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6287-6299
    • Del Gatto-Konczak, F.1    Bourgeois, C.F.2    Le Guiner, C.3    Kister, L.4    Gesnel, M.C.5    Stevenin, J.6    Breathnach, R.7
  • 80
    • 0032618278 scopus 로고    scopus 로고
    • Silver staining of 2-D electrophoresis gels
    • Rabilloud, T. (1999) Silver staining of 2-D electrophoresis gels. [i#Methods Mol. Biol.#1i], [b#112#1b], 297-305.
    • (1999) Methods Mol. Biol. , vol.112 , pp. 297-305
    • Rabilloud, T.1
  • 81
    • 0037328024 scopus 로고    scopus 로고
    • Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis
    • Cavusoglu, N., Brand, M., Tora, L. and Van Dorsselaer, A. (2003) Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis. [i#Proteomics#1i], [b#3#1b], 217-223.
    • (2003) Proteomics , vol.3 , pp. 217-223
    • Cavusoglu, N.1    Brand, M.2    Tora, L.3    Van Dorsselaer, A.4
  • 82
    • 0034705231 scopus 로고    scopus 로고
    • A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection
    • Elliott, D.J., Bourgeois, C.F., Klink, A., Stevenin, J. and Cooke, H.J. (2000) A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection. [i#Proc. Natl Acad. Sci. USA#1i], [b#97#1b], 5717-5722.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5717-5722
    • Elliott, D.J.1    Bourgeois, C.F.2    Klink, A.3    Stevenin, J.4    Cooke, H.J.5
  • 84
    • 0033593649 scopus 로고    scopus 로고
    • Regulation of the neuron-specific exon of clathrin light chain B
    • Stamm, S., Casper, D., Hanson, V. and Helfman, D.M. (1999) Regulation of the neuron-specific exon of clathrin light chain B. [i#Brain Res. Mol. Brain Res.#1i], [b#64#1b], 108-118.
    • (1999) Brain Res. Mol. Brain Res. , vol.64 , pp. 108-118
    • Stamm, S.1    Casper, D.2    Hanson, V.3    Helfman, D.M.4
  • 85
    • 9244259694 scopus 로고    scopus 로고
    • Tra2beta1 regulates P19 neuronal differentiation and the splicing of FGF-2R and GluR-B minigenes
    • Chen, X., Huang, J., Li, J., Han, Y., Wu, K. and Xu, P. (2004) Tra2beta1 regulates P19 neuronal differentiation and the splicing of FGF-2R and GluR-B minigenes. [i#Cell. Biol. Int.#1i], [b#28#1b], 791-799.
    • (2004) Cell. Biol. Int. , vol.28 , pp. 791-799
    • Chen, X.1    Huang, J.2    Li, J.3    Han, Y.4    Wu, K.5    Xu, P.6
  • 86
    • 0036844365 scopus 로고    scopus 로고
    • Exonic splicing enhancer-dependent splicing of the gonadotropin-releasing hormone premessenger ribonucleic acid is mediated by tra2alpha, a 40-kilodalton serine/arginine-rich protein
    • Seong, J.Y., Han, J., Park, S., Wuttke, W., Jarry, H. and Kim, K. (2002) Exonic splicing enhancer-dependent splicing of the gonadotropin-releasing hormone premessenger ribonucleic acid is mediated by tra2alpha, a 40-kilodalton serine/arginine-rich protein. [i#Mol. Endocrinol.#1i], [b#16#1b], 2426-2438.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 2426-2438
    • Seong, J.Y.1    Han, J.2    Park, S.3    Wuttke, W.4    Jarry, H.5    Kim, K.6
  • 87
    • 0036501065 scopus 로고    scopus 로고
    • SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1
    • Young, P.J., DiDonato, C.J., Hu, D., Kothary, R., Androphy, E.J. and Lorson, C.L. (2002) SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. [i#Hum. Mol. Genet.#1i], [b#11#1b], 577-587.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 577-587
    • Young, P.J.1    DiDonato, C.J.2    Hu, D.3    Kothary, R.4    Androphy, E.J.5    Lorson, C.L.6
  • 88
    • 0141506887 scopus 로고    scopus 로고
    • Valproic acid increases the SMN2 protein level: A well-known drug as a potential therapy for spinal muscular atrophy
    • Brichta, L., Hofmann, Y., Hahnen, E., Siebzehnrubl, F.A., Raschke, H., Blumcke, I., Eyupoglu, I.Y. and Wirth, B. (2003) Valproic acid increases the SMN2 protein level: A well-known drug as a potential therapy for spinal muscular atrophy. [i#Hum. Mol. Genet.#1i], [b#12#1b], 2481-2489.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 2481-2489
    • Brichta, L.1    Hofmann, Y.2    Hahnen, E.3    Siebzehnrubl, F.A.4    Raschke, H.5    Blumcke, I.6    Eyupoglu, I.Y.7    Wirth, B.8
  • 89
    • 0032569991 scopus 로고    scopus 로고
    • A sequence-specific splicing activator, tra2beta, is up-regulated in response to nerve injury
    • Kiryu-Seo, S., Matsuo, N., Wanaka, A., Ogawa, S., Tohyama, M. and Kiyama, H. (1998) A sequence-specific splicing activator, tra2beta, is up-regulated in response to nerve injury. [i#Brain Res. Mol. Brain Res.#1i] [b#62#1b], 220-223.
    • (1998) Brain Res. Mol. Brain Res. , vol.62 , pp. 220-223
    • Kiryu-Seo, S.1    Matsuo, N.2    Wanaka, A.3    Ogawa, S.4    Tohyama, M.5    Kiyama, H.6
  • 90
    • 0037101633 scopus 로고    scopus 로고
    • Ischemia induces a translocation of the splicing factor tra2-beta 1 and changes alternative splicing patterns in the brain
    • Daoud, R., Mies, G., Smialowska, A., Olah, L., Hossmann, K.A. and Stamm, S. (2002) Ischemia induces a translocation of the splicing factor tra2-beta 1 and changes alternative splicing patterns in the brain. [i#J. Neurosci.#1i], [b#22#1b], 5889-5899.
    • (2002) J. Neurosci. , vol.22 , pp. 5889-5899
    • Daoud, R.1    Mies, G.2    Smialowska, A.3    Olah, L.4    Hossmann, K.A.5    Stamm, S.6
  • 91
    • 0036798006 scopus 로고    scopus 로고
    • Signals and their transduction pathways regulating alternative splicing: A new dimension of the human genome
    • Stamm, S. (2002) Signals and their transduction pathways regulating alternative splicing: A new dimension of the human genome. [i#Hum. Mol. Genet.#1i], [b#11#1b], 2409-2416.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2409-2416
    • Stamm, S.1
  • 92
    • 0035003275 scopus 로고    scopus 로고
    • Expression of a novel RNA-splicing factor, RA301/Tra2beta, in vascular lesions and its role in smooth muscle cell proliferation
    • Tsukamoto, Y., Matsuo, N., Ozawa, K., Hori, O., Higashi, T., Nishizaki, J., Tohnai, N., Nagata, I., Kawano, K., Yutani, C. [i#et al.#1i] (2001) Expression of a novel RNA-splicing factor, RA301/Tra2beta, in vascular lesions and its role in smooth muscle cell proliferation. [i#Am. J. Pathol.#1i], [b#158#1b], 1685-1694.
    • (2001) Am. J. Pathol. , vol.158 , pp. 1685-1694
    • Tsukamoto, Y.1    Matsuo, N.2    Ozawa, K.3    Hori, O.4    Higashi, T.5    Nishizaki, J.6    Tohnai, N.7    Nagata, I.8    Kawano, K.9    Yutani, C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.