메뉴 건너뛰기




Volumn 93, Issue 1, 1998, Pages 139-148

Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing

Author keywords

[No Author keywords available]

Indexed keywords

RNA BINDING PROTEIN; RNA BINDING PROTEIN TRA2; UNCLASSIFIED DRUG;

EID: 0032478506     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81153-8     Document Type: Article
Times cited : (183)

References (64)
  • 1
    • 0024255702 scopus 로고
    • The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein
    • Amrein, H., Gorman, M., and Nöthiger, R. (1988). The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein. Cell 55, 1025-1035.
    • (1988) Cell , vol.55 , pp. 1025-1035
    • Amrein, H.1    Gorman, M.2    Nöthiger, R.3
  • 2
    • 0028324929 scopus 로고
    • The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by transformer 2
    • Amrein, H., Hedley, M.L., and Maniatis, T. (1994). The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by transformer 2. Cell 76, 735-746.
    • (1994) Cell , vol.76 , pp. 735-746
    • Amrein, H.1    Hedley, M.L.2    Maniatis, T.3
  • 3
    • 0019296946 scopus 로고
    • Sex and the single cell: I. On the action of major loci affecting sex determination in Drosophila melanogaster
    • Baker, B.S., and Ridge, K.A. (1980). Sex and the single cell: I. on the action of major loci affecting sex determination in Drosophila melanogaster. Genetics 94, 383-423.
    • (1980) Genetics , vol.94 , pp. 383-423
    • Baker, B.S.1    Ridge, K.A.2
  • 4
    • 0031010564 scopus 로고    scopus 로고
    • Molecular cloning of htra2β-1 and htra2β-2, two human homologs of tra-2 generated by alternative splicing
    • Beil, B., Screaton, G., and Stamm, S. (1997). Molecular cloning of htra2β-1 and htra2β-2, two human homologs of tra-2 generated by alternative splicing. DNA and Cell Biol. 16, 679-690.
    • (1997) DNA and Cell Biol. , vol.16 , pp. 679-690
    • Beil, B.1    Screaton, G.2    Stamm, S.3
  • 5
    • 0027753933 scopus 로고
    • Analysis of the RNA-recognition motif and RS and RGG domains: Conservation in metazoan pre-mRNA splicing factors
    • Birney, E., Kumar, S., and Krainer, A.R. (1993). Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors. Nucleic Acids Res. 21, 5803-5816.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5803-5816
    • Birney, E.1    Kumar, S.2    Krainer, A.R.3
  • 6
    • 0027495444 scopus 로고
    • The regulation of sex determination and sexually dimorphic differentiation in Drosophila
    • Burtis, K.C. (1993). The regulation of sex determination and sexually dimorphic differentiation in Drosophila. Curr. Opin. Cell Biol. 5, 1006-1014.
    • (1993) Curr. Opin. Cell Biol. , vol.5 , pp. 1006-1014
    • Burtis, K.C.1
  • 7
    • 0028077730 scopus 로고
    • Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors
    • Caceres, J.F., Stamm, S., Helfman, D.M., and Krainer, A.R. (1994). Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science 265, 1706-1709.
    • (1994) Science , vol.265 , pp. 1706-1709
    • Caceres, J.F.1    Stamm, S.2    Helfman, D.M.3    Krainer, A.R.4
  • 8
    • 0030891302 scopus 로고    scopus 로고
    • RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins
    • Chandler, S.D., Mayeda, A., Yeakley, J.M., Krainer, A.R., and Fu, X.D. (1997). RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins. Proc. Natl. Acad. Sci. USA 94, 3596-3601.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3596-3601
    • Chandler, S.D.1    Mayeda, A.2    Yeakley, J.M.3    Krainer, A.R.4    Fu, X.D.5
  • 9
    • 0030028882 scopus 로고    scopus 로고
    • The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intracellular distribution
    • Colwill, K., Pawson, T., Andrews, B., Prasad, J., Manley, J.L., Bell, J.C., and Duncan, P.I. (1996). The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intracellular distribution. EMBO J. 15, 265-275.
    • (1996) EMBO J. , vol.15 , pp. 265-275
    • Colwill, K.1    Pawson, T.2    Andrews, B.3    Prasad, J.4    Manley, J.L.5    Bell, J.C.6    Duncan, P.I.7
  • 10
    • 0028034324 scopus 로고
    • Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP
    • Crispino, J.D., Blencowe, B.J., and Sharp, P.A. (1994). Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP. Science 265, 1866-1869.
    • (1994) Science , vol.265 , pp. 1866-1869
    • Crispino, J.D.1    Blencowe, B.J.2    Sharp, P.A.3
  • 11
    • 0029831071 scopus 로고    scopus 로고
    • A human homolog of the Drosophila sex determination factor transformer-2 has conserved splicing regulatory functions
    • Dauwalder, B., Amaya-Manzanares, F., and Mattox, W. (1996). A human homolog of the Drosophila sex determination factor transformer-2 has conserved splicing regulatory functions. Proc. Natl. Acad. Sci. USA 93, 9004-9009.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9004-9009
    • Dauwalder, B.1    Amaya-Manzanares, F.2    Mattox, W.3
  • 12
    • 2642660440 scopus 로고    scopus 로고
    • A short sequence within two purine-rich enhancers determines 5′ splice site specificity
    • Elrick, L.L., Humphrey, M.B., Cooper, T.A., and Berget, S.M. (1998). A short sequence within two purine-rich enhancers determines 5′ splice site specificity. Mol. Cell. Biol. 18, 343-352.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 343-352
    • Elrick, L.L.1    Humphrey, M.B.2    Cooper, T.A.3    Berget, S.M.4
  • 13
    • 0027424442 scopus 로고
    • Specific commitment of different pre-RNAs to splicing by single SR proteins
    • Fu, X.D. (1993). Specific commitment of different pre-RNAs to splicing by single SR proteins. Nature 365, 82-85.
    • (1993) Nature , vol.365 , pp. 82-85
    • Fu, X.D.1
  • 14
    • 0029372979 scopus 로고
    • The superfamily of arginine/serine-rich splicing factors
    • Fu, X.D. (1995). The superfamily of arginine/serine-rich splicing factors. RNA 1, 663-680.
    • (1995) RNA , vol.1 , pp. 663-680
    • Fu, X.D.1
  • 15
    • 0025827463 scopus 로고
    • Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators
    • Ge, H., Zuo, P., and Manley, J.L. (1991). Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell 66, 373-382.
    • (1991) Cell , vol.66 , pp. 373-382
    • Ge, H.1    Zuo, P.2    Manley, J.L.3
  • 16
    • 0024512392 scopus 로고
    • The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins
    • Goralski, T.J., Edstrom, J.E., and Baker, B.S. (1989). The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins. Cell 56, 1011-1018.
    • (1989) Cell , vol.56 , pp. 1011-1018
    • Goralski, T.J.1    Edstrom, J.E.2    Baker, B.S.3
  • 17
    • 0028286596 scopus 로고
    • A serine kinase regulates intracellular localization of splicing factors in the cell cycle
    • Gui, J.F., Lane, W.S., and Fu, X.D. (1994). A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Nature 369, 678-682.
    • (1994) Nature , vol.369 , pp. 678-682
    • Gui, J.F.1    Lane, W.S.2    Fu, X.D.3
  • 18
    • 0027961082 scopus 로고
    • Sex-specific processing of the Drosophila exuperantia transcript is regulated in male germ cells by the tra-2 gene
    • Hazelrigg, T., and Tu, C. (1994). Sex-specific processing of the Drosophila exuperantia transcript is regulated in male germ cells by the tra-2 gene. Proc. Natl. Acad. Sci. USA 91, 10752-10756.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10752-10756
    • Hazelrigg, T.1    Tu, C.2
  • 19
    • 0029114121 scopus 로고
    • The Drosophila SR protein RBP1 contributes to the regulation of doublesex alternative splicing by recognizing RBP1 RNA target sequences
    • Heinrichs, V., and Baker, B.S. (1995). The Drosophila SR protein RBP1 contributes to the regulation of doublesex alternative splicing by recognizing RBP1 RNA target sequences. EMBO J. 14, 3987-4000.
    • (1995) EMBO J. , vol.14 , pp. 3987-4000
    • Heinrichs, V.1    Baker, B.S.2
  • 20
    • 0031972648 scopus 로고    scopus 로고
    • Regulation of sex-specific selection of fruitless 5′ splice sites by transformer and transformer-2
    • Heinrichs, V., Ryner, L.C., and Baker, B. (1998). Regulation of sex-specific selection of fruitless 5′ splice sites by transformer and transformer-2. Mol. Cell. Biol. 18, 450-458.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 450-458
    • Heinrichs, V.1    Ryner, L.C.2    Baker, B.3
  • 21
    • 0025815671 scopus 로고
    • Control of double-sex alternative splicing by transformer and transformer-2 in Drosophila
    • Hoshijima, K., Inoue, K., Higuchi, I., Sakamoto, H., and Shimura, Y. (1991). Control of double-sex alternative splicing by transformer and transformer-2 in Drosophila. Science 252, 833-836.
    • (1991) Science , vol.252 , pp. 833-836
    • Hoshijima, K.1    Inoue, K.2    Higuchi, I.3    Sakamoto, H.4    Shimura, Y.5
  • 22
    • 0026756495 scopus 로고
    • Binding of the Drosophila transformer and transformer-2 proteins to the regulatory elements of double-sex primary transcript for sex-specific RNA processing
    • Inoue, K., Hoshijima, K., Higuchi, I., Sakamoto, H., and Shimura, Y. (1992). Binding of the Drosophila transformer and transformer-2 proteins to the regulatory elements of double-sex primary transcript for sex-specific RNA processing. Proc. Natl. Acad. Sci. USA 89, 8092-8096.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8092-8096
    • Inoue, K.1    Hoshijima, K.2    Higuchi, I.3    Sakamoto, H.4    Shimura, Y.5
  • 23
  • 24
    • 0025743575 scopus 로고
    • Functional expression of cloned human splicing factor SF2: Homology to RNA-binding proteins, U170K and Drosophila splicing regulators
    • Krainer, A.R., Mayeda, A., Kozak, D., and Binns, G. (1991). Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U170K and Drosophila splicing regulators. Cell 66, 383-394.
    • (1991) Cell , vol.66 , pp. 383-394
    • Krainer, A.R.1    Mayeda, A.2    Kozak, D.3    Binns, G.4
  • 25
    • 0027143943 scopus 로고
    • A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding
    • Lavigueur, A., La Branche, H., Kornblihtt, A.R., and Chabot, B. (1993). A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding. Genes Dev. 7, 2405-2417.
    • (1993) Genes Dev. , vol.7 , pp. 2405-2417
    • Lavigueur, A.1    La Branche, H.2    Kornblihtt, A.R.3    Chabot, B.4
  • 26
    • 0028926275 scopus 로고
    • Synergistic interactions between two distinct elements of a regulated splicing enhancer
    • Lynch, K.W., and Maniatis, T. (1995). Synergistic interactions between two distinct elements of a regulated splicing enhancer. Genes Dev. 9, 284-293.
    • (1995) Genes Dev. , vol.9 , pp. 284-293
    • Lynch, K.W.1    Maniatis, T.2
  • 27
    • 0029858338 scopus 로고    scopus 로고
    • Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer
    • Lynch, K.W., and Maniatis, T. (1996). Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer. Genes Dev. 10, 2089-2101.
    • (1996) Genes Dev. , vol.10 , pp. 2089-2101
    • Lynch, K.W.1    Maniatis, T.2
  • 28
    • 0029998486 scopus 로고    scopus 로고
    • Att, a target for regulation by tra2 in the testes of Drosophila melanogaster, encodes alternative RNAs and alternative proteins
    • Madigan, S.J., Edeen, P., Esnayra, J., and McKeown, M. (1996). att, a target for regulation by tra2 in the testes of Drosophila melanogaster, encodes alternative RNAs and alternative proteins. Mol. Cell. Biol. 16, 4222-4230.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4222-4230
    • Madigan, S.J.1    Edeen, P.2    Esnayra, J.3    McKeown, M.4
  • 29
    • 0029767662 scopus 로고    scopus 로고
    • SR proteins and splicing control
    • Manley, J.L., and Tacke, R. (1996). SR proteins and splicing control. Genes Dev. 10, 1569-1579.
    • (1996) Genes Dev. , vol.10 , pp. 1569-1579
    • Manley, J.L.1    Tacke, R.2
  • 30
    • 0028807463 scopus 로고
    • Cloning of a novel RNA binding polypeptide (RA301) induced by hypoxia/reoxygenation
    • Matsuo, N., Ogawa, S., Imai, Y., Takagi, T., Tohyama, M., Stern, D., and Wanaka, A. (1995). Cloning of a novel RNA binding polypeptide (RA301) induced by hypoxia/reoxygenation. J. Biol. Chem. 270, 28216-28222.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28216-28222
    • Matsuo, N.1    Ogawa, S.2    Imai, Y.3    Takagi, T.4    Tohyama, M.5    Stern, D.6    Wanaka, A.7
  • 31
    • 0025732078 scopus 로고
    • Autoregulation of the splicing of transcripts from the transformer-2 gene of Drosophila
    • Mattox, W., and Baker, B.S. (1991). Autoregulation of the splicing of transcripts from the transformer-2 gene of Drosophila. Genes Dev. 5, 786-796.
    • (1991) Genes Dev. , vol.5 , pp. 786-796
    • Mattox, W.1    Baker, B.S.2
  • 32
    • 0029912882 scopus 로고    scopus 로고
    • A negative feedback mechanism revealed by functional analysis of the alternative isoforms of the Drosophila splicing regulator transformer-2
    • Mattox, W., McGuffin, M.E., and Baker, B.S. (1996). A negative feedback mechanism revealed by functional analysis of the alternative isoforms of the Drosophila splicing regulator transformer-2. Genetics 143, 303-314.
    • (1996) Genetics , vol.143 , pp. 303-314
    • Mattox, W.1    McGuffin, M.E.2    Baker, B.S.3
  • 33
    • 0028832642 scopus 로고
    • Genetic enhancement of RNA processing defects by a dominant mutation in B52, the Drosophila geneforan SR protein splicing factor
    • Peng, X., 61nd Mount, S.M. (1995). Genetic enhancement of RNA processing defects by a dominant mutation in B52, the Drosophila geneforan SR protein splicing factor. Mol. Cell. Biol. 15, 6273-6282.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6273-6282
    • Peng, X.1    Mount, S.M.2
  • 34
    • 0029144216 scopus 로고
    • A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer
    • Ramchatesingh, J., Zahler, A.M., Neugebauer, K.M., Roth, M.B., and Cooper, T.A. (1995). A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. Mol. Cell. Biol. 15, 4898-4907.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4898-4907
    • Ramchatesingh, J.1    Zahler, A.M.2    Neugebauer, K.M.3    Roth, M.B.4    Cooper, T.A.5
  • 35
    • 0028046121 scopus 로고
    • The SR protein B52/SRp55 is essential for Drosophila development
    • Ring, H.Z., and Lis, J.T. (1994). The SR protein B52/SRp55 is essential for Drosophila development. Mol. Cell. Biol. 14, 7499-7506.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7499-7506
    • Ring, H.Z.1    Lis, J.T.2
  • 36
    • 0025931225 scopus 로고
    • A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription
    • Roth, M.B., Zahler, A.M., and Stolk, J.A. (1991). A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription. J. Cell Biol. 115, 587-596.
    • (1991) J. Cell Biol. , vol.115 , pp. 587-596
    • Roth, M.B.1    Zahler, A.M.2    Stolk, J.A.3
  • 37
    • 0030010743 scopus 로고    scopus 로고
    • Muscle-specific splicing enhancers regulate inclusion of the cardiac troponin T alternative exon in embryonic skeletal muscle
    • Ryan, K.J., and Cooper, T.A. (1996). Muscle-specific splicing enhancers regulate inclusion of the cardiac troponin T alternative exon in embryonic skeletal muscle. Mol. Cell. Biol. 16, 4014-4023.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4014-4023
    • Ryan, K.J.1    Cooper, T.A.2
  • 40
    • 0029903184 scopus 로고    scopus 로고
    • Molecular cloning of a mouse homolog for the Drosophila splicing regulator Tra2
    • Segade, F., Hurlé, B., Claudio, E., Ramos, S., and Lazo, P.S. (1996). Molecular cloning of a mouse homolog for the Drosophila splicing regulator Tra2. FEBS Lett. 387, 152-156.
    • (1996) FEBS Lett. , vol.387 , pp. 152-156
    • Segade, F.1    Hurlé, B.2    Claudio, E.3    Ramos, S.4    Lazo, P.S.5
  • 41
    • 0028006713 scopus 로고
    • SR proteins promote the first specific recognition of pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex
    • Staknis, D., and Reed, R. (1994). SR proteins promote the first specific recognition of pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex. Mol. Cell. Biol. 14, 7670-7682.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7670-7682
    • Staknis, D.1    Reed, R.2
  • 42
    • 0027715743 scopus 로고
    • General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer
    • Sun, Q., Mayeda, A., Hampson, R.K., Krainer, A.R., and Rottman, F.M. (1993). General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer. Genes Dev. 7, 2598-2608.
    • (1993) Genes Dev. , vol.7 , pp. 2598-2608
    • Sun, Q.1    Mayeda, A.2    Hampson, R.K.3    Krainer, A.R.4    Rottman, F.M.5
  • 43
    • 0029064220 scopus 로고
    • The human splicing factors ASF/ SF2 and SC35 possess different, functionally significant RNA binding specificities
    • Tacke, R., and Manley, J.L. (1995). The human splicing factors ASF/ SF2 and SC35 possess different, functionally significant RNA binding specificities. EMBO J. 14, 3540-3551.
    • (1995) EMBO J. , vol.14 , pp. 3540-3551
    • Tacke, R.1    Manley, J.L.2
  • 44
    • 0031037690 scopus 로고    scopus 로고
    • Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: Creation of an SRp40-specific splicing enhancer
    • Tacke, R., Chen, Y., and Manley, J.L. (1997). Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer. Proc. Natl. Acad. Sci. USA 94, 1148-1153.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1148-1153
    • Tacke, R.1    Chen, Y.2    Manley, J.L.3
  • 45
    • 0028118641 scopus 로고
    • Polypurine sequences within a downstream exon function as asplicing enhancer
    • Tanaka, K., Watakabe, A., and Shimura, Y. (1994). Polypurine sequences within a downstream exon function as asplicing enhancer. Mol. Cell. Biol. 14, 1347-1354.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1347-1354
    • Tanaka, K.1    Watakabe, A.2    Shimura, Y.3
  • 46
    • 0028072388 scopus 로고
    • SR proteins can compensate for the loss of U1 snRNP functions in vitro
    • Tarn, W.Y., and Steitz, J.A. (1994). SR proteins can compensate for the loss of U1 snRNP functions in vitro. Genes Dev. 8, 2704-2717.
    • (1994) Genes Dev. , vol.8 , pp. 2704-2717
    • Tarn, W.Y.1    Steitz, J.A.2
  • 47
    • 0026579802 scopus 로고
    • Positive control of pre-mRNA splicing in vitro
    • Tian, M., and Maniatis, T. (1992). Positive control of pre-mRNA splicing in vitro. Science 256, 237-240.
    • (1992) Science , vol.256 , pp. 237-240
    • Tian, M.1    Maniatis, T.2
  • 48
    • 0027185151 scopus 로고
    • A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA
    • Tian, M., and Maniatis, T. (1993). A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA. Cell 74, 105-114.
    • (1993) Cell , vol.74 , pp. 105-114
    • Tian, M.1    Maniatis, T.2
  • 49
    • 0028025033 scopus 로고
    • A splicing enhancer exhibits both constitutive and regulated activities
    • Tian, M., and Maniatis, T. (1994). A splicing enhancer exhibits both constitutive and regulated activities. Genes Dev. 8, 1703-1712.
    • (1994) Genes Dev. , vol.8 , pp. 1703-1712
    • Tian, M.1    Maniatis, T.2
  • 50
    • 0039769985 scopus 로고    scopus 로고
    • 65 and SR proteins in splicing of pre-mRNA
    • 65 and SR proteins in splicing of pre-mRNA. Nature 388, 397-400.
    • (1997) Nature , vol.388 , pp. 397-400
    • Tronchère, H.1    Wang, J.2    Fu, X.D.3
  • 51
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk, C., and Gold, L. (1990). Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249, 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 52
    • 0030218143 scopus 로고    scopus 로고
    • The SR protein family: Pleiotropic functions in pre-mRNA splicing
    • Valcárcel, J., and Green, M.R. (1996). The SR protein family: pleiotropic functions in pre-mRNA splicing. Trends Biochem. Sci. 21, 296-301.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 296-301
    • Valcárcel, J.1    Green, M.R.2
  • 53
    • 0027400786 scopus 로고
    • The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA
    • Valcárcel, J., Singh, R., Zamore, P.D., and Green, M.R. (1993). The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA. Nature 362, 171-175.
    • (1993) Nature , vol.362 , pp. 171-175
    • Valcárcel, J.1    Singh, R.2    Zamore, P.D.3    Green, M.R.4
  • 54
    • 0029295349 scopus 로고
    • Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways
    • Wang, J., and Manley, J.L. (1995). Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways. RNA 1, 335-346.
    • (1995) RNA , vol.1 , pp. 335-346
    • Wang, J.1    Manley, J.L.2
  • 55
    • 0029859659 scopus 로고    scopus 로고
    • Targeted disruption of an essential vertebrate gene, ASF/SF2 is required for cell viability
    • Wang, J., Takagaki, Y., and Manley, J.L. (1996). Targeted disruption of an essential vertebrate gene, ASF/SF2 is required for cell viability. Genes Dev. 10, 2588-2599.
    • (1996) Genes Dev. , vol.10 , pp. 2588-2599
    • Wang, J.1    Takagaki, Y.2    Manley, J.L.3
  • 56
    • 0027288912 scopus 로고
    • The role of exon sequences in splice site selection
    • Watakabe, A., Tanaka, K., and Shimura, Y. (1993). The role of exon sequences in splice site selection. Genes Dev. 7, 407-418.
    • (1993) Genes Dev. , vol.7 , pp. 407-418
    • Watakabe, A.1    Tanaka, K.2    Shimura, Y.3
  • 57
    • 0027137934 scopus 로고
    • Specific interactions between proteins implicated in splice site selection and regulated alternative splicing
    • Wu, J.Y., and Maniatis, T. (1993). Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell 75, 1061-1070.
    • (1993) Cell , vol.75 , pp. 1061-1070
    • Wu, J.Y.1    Maniatis, T.2
  • 58
    • 0031042396 scopus 로고    scopus 로고
    • Phosphorylation of the ASF/SF2 RS domain affects both protein-protein interactions and protein-RNA interactions and is necessary for splicing
    • Xiao, S.H., and Manley, J.L. (1997). Phosphorylation of the ASF/SF2 RS domain affects both protein-protein interactions and protein-RNA interactions and is necessary for splicing. Genes Dev. 11, 334-344.
    • (1997) Genes Dev. , vol.11 , pp. 334-344
    • Xiao, S.H.1    Manley, J.L.2
  • 59
    • 0027175502 scopus 로고
    • The cardiac troponin T alternative exon contains a novel purine-rich positive splicing element
    • Xu, R., Teng, J., and Cooper, T.A. (1993). The cardiac troponin T alternative exon contains a novel purine-rich positive splicing element. Mol. Cell. Biol. 13, 3660-3674.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3660-3674
    • Xu, R.1    Teng, J.2    Cooper, T.A.3
  • 60
    • 0027522106 scopus 로고
    • Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements
    • Yeakley, J.M., Hedjran, F., Morfin, J.-P., Merillat, N., Rosenfeld, M.G., and Emeson, R.B. (1993). Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements. Mol. Cell. Biol. 13, 5999-6011.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5999-6011
    • Yeakley, J.M.1    Hedjran, F.2    Morfin, J.-P.3    Merillat, N.4    Rosenfeld, M.G.5    Emeson, R.B.6
  • 61
    • 0029797697 scopus 로고    scopus 로고
    • A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer
    • Yeakley, J.M., Morfin, J.-P., Rosenfeld, M.G., and Fu, X.D. (1996). A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer. Proc. Natl. Acad. Sci. USA 93, 7582-7587.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7582-7587
    • Yeakley, J.M.1    Morfin, J.-P.2    Rosenfeld, M.G.3    Fu, X.D.4
  • 62
    • 0026716104 scopus 로고
    • SR proteins: A conserved family of pre-mRNA splicing factors
    • Zahler, A.M., Lane, W.S., Stolk, J.A., and Roth, M.B. (1992). SR proteins: a conserved family of pre-mRNA splicing factors. Genes Dev. 6, 837-847.
    • (1992) Genes Dev. , vol.6 , pp. 837-847
    • Zahler, A.M.1    Lane, W.S.2    Stolk, J.A.3    Roth, M.B.4
  • 63
    • 0027160003 scopus 로고
    • Distinct functions of SR proteins in alternative pre-mRNA splicing
    • Zahler, A.M., Neugenbauer, K.M., Lane, W.S., and Roth, M.B. (1993). Distinct functions of SR proteins in alternative pre-mRNA splicing. Science 260, 219-222.
    • (1993) Science , vol.260 , pp. 219-222
    • Zahler, A.M.1    Neugenbauer, K.M.2    Lane, W.S.3    Roth, M.B.4
  • 64
    • 0029665533 scopus 로고    scopus 로고
    • 35 mediates critical protein-protein interactions in constitutive and enhancerdependent splicing
    • 35 mediates critical protein-protein interactions in constitutive and enhancerdependent splicing. Genes Dev. 10, 1356-1368.
    • (1996) Genes Dev. , vol.10 , pp. 1356-1368
    • Zuo, P.1    Maniatis, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.