Human transformer-2-beta gene (SFRS10): Complete nucleotide sequence, chromosomal localization, and generation of a tissue-specific isoform

Genomics

Volumn 53, Issue 2, 1998, Pages 191-202

  Nayler, Oliver ^b   Cap, Claudia ^a   Stamm, Stefan ^a  

^a MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; MESSENGER RNA PRECURSOR; RNA; SMALL NUCLEAR RNA; SYNTHETIC PEPTIDE;

ARTICLE; CELLULAR DISTRIBUTION; CHROMOSOMAL LOCALIZATION; CHROMOSOME 3Q; DROSOPHILA; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN RNA BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; TISSUE SPECIFICITY;

EID: 17144453865     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5471     Document Type: Article

References (63)

1. Amrein H., Hedley M. L., Maniatis T. The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by transformer 2. Cell. 76:1994;735-746.
2. Atanasoski S., Toldo S. S., Malipiero U., Schreiber E., Fries R., Fontana A. Isolation of the human genomic brain-2/N-Oct 3 gene (POUF3) and assignment to chromosome 6q16. Genomics. 26:1995;272-280.
3. Ayane M., Preuss U., Köhler G., Nielsen P. J. A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs. Nucleic Acids Res. 19:1991;1273-1278.
4. Beil B., Screaton G., Stamm S. Molecular cloning of htra2-beta-1 and htra2-beta-2, two human homologues of tra-2 generated by alternative splicing. DNA Cell Biol. 16:1997;679-690.
5. Boggs R. T., Gregor P., Idriss S., Belote J. M., McKeown M. Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene. Cell. 50:1987;739-747.
6. Cáceres J., Stamm S., Helfman D. M., Krainer A. R. Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science. 265:1994;1706-1709.
7. Chandler D., McGuffin M. E., Piskur J., Yao J., Baker B., Mattox W. Evolutionary conservation of regulatory strategies for the sex determination factor transformer-2. Mol. Cell. Biol. 1997;2908-2919.
8. Chou T. B., Zachar Z., Bingham P. M. Developmental expression of a regulatory gene is programmed at the level of splicing. EMBO J. 6:1987;4095-4104.
9. Colwill K., Pawson T., Andrews B., Prasad J., Manley J. L., Bell J. C., Duncan P. I. The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. EMBO J. 15:1996;265-275.
10. Cross S. H., Charlton J. A., Nan X., Bird A. P. Purification of CPG islands using a methylated DNA binding RT column. Nat. Genet. 6:1994;236-244.
11. Dauwalder B., Amaya-Manzanares F., Mattox W. A human homologue of theDrosophila. Proc. Natl. Acad. Sci. USA. 93:1996;9004-9009.
12. Delsert C. D., Rosenfeld M. G. A tissue specific small nuclear ribonucleoprotein and the regulated splicing of the calcitonin/calcitonin gene-related protein transcript. J. Biol. Chem. 267:1992;14573-14579.
13. Dreyfuss G., Matunis M. J., Piñol-Roma S., Burd C. G. hnRNP proteins and the biogenesis of mRNA. Annu. Rev. Biochem. 62:1993;289-321.
14. Fu X.-D. The superfamily of arginine/serine-rich splicing factors. RNA. 1:1995;663-680.
15. Ge H., Manley J. L. A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell. 62:1990;25-34.
16. Ge H., Zuo P., Manley J. L. Primary structure of the human splicing factor ASF reveals similarities withDrosophila. Cell. 66:1991;373-382.
17. Genetics Computer Group, 1994.
18. Gui J.-F., Lane W. S., Fu X.-D. A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Nature. 369:1993;678-682.
19. Hayashizaki Y., Shibata H., Hirotsune S., Sugino H., Okazaki Y., Sasaki N., Hirose K., Imoto H., Okuizumi H., Muramatsu M., Komatsubara H., Shiroishi T., Moriwaki K., Katsuki M., Hatano N., Sasaki H., Ueda T., Mise N., Takagi N., Plass C., Chapman V. M. Identification of an imprinted U2AF binding protein related sequence on mouse chromosome 11 using the RLGS method. Nat. Genet. 6:1994;33-40.
20. Hazelrigg T., Tu C. Sex-specific processing of theDrosophila. Proc. Natl. Acad. Sci. USA. 91:1994;10752-10756.
21. Heinrichs V., Ryner L. C., Baker B. Regulation of sex-specific selection of fruitless 5′ splice sites by transformer and transformer-2. Mol. Cell. Biol. 18:1998;450-458.
22. Jumaa H., Guenet J.-L., Nielsen P. J. Regulated expression and RNA processing of transcripts from the SRp20 splicing factor gene during the cell cycle. Mol. Cell. Biol. 17:1997;3116-3124.
23. Jumaa H., Nielsen P. J. The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation. EMBO J. 16:1997;5077-5085.
24. Jurka J., Milosavljevic A. Reconstruction and analysis of human Alu genes. J. Mol. Evol. 32:1991;105-121.
25. Kim Y. J., Zuo P., Manley J. L., Baker B. S. TheDrosophila. Genes Dev. 6:1992;2569-2579.
26. Koushika S. P., Lisbin M. J., White K. Elav, aDrosophila. Curr. Biol. 6:1996;1634-1641.
27. Krämer A. The structure and function of proteins involved in mammalian pre-mRNA splicing. Annu. Rev. Biochem. 65:1996;367-409.
28. Leff S. E., Branna C. I., Reed M. L., Ozcelik T., Francke U., Copeland N. G., Jenkins N. A. Maternal imprinting of the mouse SNRPN gene and conserved linkage homology with the human Prader-Willi syndrome region. Nat. Genet. 2:1993;259-263.
29. Lennon G. G., Auffray C., Polymeropoulos M., Soares M. B. The I.M.A.G.E. Consortium: An integrated molecular analysis of genomes and their expression. Genomics. 33:1996;151-152.
30. Madigan S. J., Edeen P., Esnayra J., McKeown M. att, a target for regulation by tra2 in the testes ofDrosophila melanogaster, Mol. Cell. Biol. 16:1996;4222-4230.
31. Manley J. L., Tacke R. SR proteins and splicing control. Genes Dev. 10:1996;1569-1579.
32. Matsuo N., Ogawa S., Imai Y., Takagi T., Tohyama M., Stern D., Wanaka A. Cloning of a novel RNA binding polypeptide (RA301) induced by hypoxia/reoxygenation. J. Biol. Chem. 270:1995;28216-28222.
33. Mattox W., Baker B. S. Autoregulation of the splicing of transcripts from the transformer-2 gene ofDrosophila. Genes Dev. 5:1991;786-796.
34. Mattox W., Palmer M. J., Baker B. S. Alternative splicing of the sex determination gene transformer-2 is sex-specific in the germ line but not in the soma. Genes Dev. 4:1990;789-805.
35. Mayeda A., Krainer A. R. Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell. 68:1992;365-375.
36. Mermoud J. E., Cohen P., Lamond A. I. Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism. EMBO J. 13:1994;5679-5688.
37. Miki Y., Katagiri T., Kasumi F., Yoshimoto T., Nakamura Y. Mutation analysis in the BRCA2 gene in primary breast cancers. Nat. Genet. 13:1996;245-247.
38. Morrison M., Harris K. S., Roth M. B. smg mutants affect the expression of alternatively spliced SR protein mRNAs inCaenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 94:1997;9782-9785.
39. Nayler O., Stamm S., Ullrich A. Characterisation and comparison of four SR protein kinases. Biochem. J. 326:1997;693-700.
40. Nayler O., Strätling W., Bourquin J.-P., Stagljar I., Lindemann L., Jasper H., Hartmann A. M., Fackelmeyer F. O., Ullrich A., Stamm S. SAF-B couples transcription and pre-mRNA splicing to SAR/MAR elements. Nucleic Acids Res. 26:1998;3542-3549.
41. Nikolakaki E., Simos G., Georgatos S. D., Giannakouros T. A nuclear envelope-associated kinase phosphorylates arginine-serine motifs and modulates interactions between the lamin B receptor and other nuclear proteins. J. Biol. Chem. 271:1996;8365-8372.
42. Nishiyama H., Itoh K., Kaneko Y., Kishishita M., Yoshida O., Fujita J. A glycine rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth. J. Cell. Biol. 137:1997;899-908.
43. Popielarz M., Cavaloc Y., Mattei M. G., Gattoni R., Stevenin J. The gene encoding human splicing factor 9G8. Structure, chromosomal localization, and expression of alternatively processed transcripts. J. Biol. Chem. 270:1995;17830-17835.
44. Ruiz-Echevarria M. J., Czaplinski K., Peltz S. Making sense of nonsense in yeast. Trends Biol. Sci. 21:1996;433-437.
45. Sarkissian M., Winne A., Lafyatis R. The mammalian homolog of suppressor-of-white-apricot regulates alternative messenger-RNA splicing of cd45 exon-4 and fibronectin iiics. J. Biol. Chem. 271:1996;31106-31114.
46. Schmauss C., McAllister G., Ohosone Y., Hardin J. A., Lerner M. R. A comparison of snRNP-associated Sm-autoantigens: Human N, rat N and human B/B′ Nucleic Acids Res. 17:1989;1733-1743.
47. Screaton G. R., Caceres J. F., Mayeda A., Bell M. V., Plebanski M., Jackson D. G., Bell J. I., Krainer A. R. Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. EMBO J. 14:1995;4336-4349.
48. Segade F., Hurle B., Claudio E., Ramos S., Lazo P. S. Molecular cloning of a mouse homologue for theDrosophila. FEBS Lett. 387:1996;152-156.
49. Snow B. E., Heng H. H. Q., Shi X.-M., Zhou Y., Du K., Taub R., Tsui L.-C., McInnes R. R. Expression analysis and chromosomal assignment of the human SFRS5/SRp40 gene. Genomics. 43:1997;165-170.
50. Spritz R. A., Strunk K., Surowy C. S., Mohrenweiser H. W. Human U1-70K ribonucleoprotein antigen gene: Organization, nucleotide sequence, and mapping to locus 19q13.3. Genomics. 8:1990;371-379.
51. Stamm S., Zhang M. Q., Marr T. G., Helfman D. M. A sequence compilation and comparison of exons that are alternatively spliced in neurons. Nucleic Acids Res. 22:1994;1515-1526.
52. Sureau A., Perbal B. Several mRNAs with variable 3′untranslated regions and different stability encode the human PR264/SC35 splicing factor. Proc. Natl. Acad. Sci. USA. 91:1994;932-936.
53. Tacke R., Tohyama M., Ogawa S., Manley J. L. Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing. Cell. 93:1998;139-148.
54. Valcárcel J., Green M. R. The SR protein family: Pleiotropic functions in pre-mRNA splicing. Trends Biochem. Sci. 21:1996;296-301.
55. Wang J., Manley J. L. Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways. RNA. 1:1995;335-346.
56. Watakabe A., Tanaka K., Shimura Y. The role of exon sequences in splice site selection. Genes Dev. 7:1993;407-418.
57. Weighardt F., Biamonti G., Riva S. The role of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism. BioEssays. 18:1996;747-756.
58. Will C. L., Behrens S. E., Lührmann R. Protein composition of mammalian spliceosomal snRNPs. Mol. Biol. Rep. 18:1993;121-126.
59. Will C. L., Lührmann R. Protein functions in pre-mRNA splicing. Curr. Opin. Cell Biol. 9:1997;320-328.
60. Woppmann A., Will C. L., Kornstadt U., Zuo P., Manley J. L., Lührmann R. Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors. Nucleic Acids Res. 21:1993;2815-2822.
61. Wu J. Y., Maniatis T. Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell. 75:1993;1061-1070.
62. Xu R., Teng J., Cooper T. A. The cardiac troponin T alternative exon contains a novel purine-rich positive splicing element. Mol. Cell. Biol. 13:1993;3660-3674.
63. Zahler A. M., Neugebauer K. M., Lane W. S., Roth M. B. Distinct functions of SR proteins in alternative pre-mRNA splicing. Science. 260:1993;219-222.