The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 15, 2003, Pages 8933-8938

  Holbro, Thomas ^a   Beerli, Roger R ^b,c   Maurer, Francisca ^a   Koziczak, Magdalena ^a   Barbas III, Carlos F ^b   Hynes, Nancy E ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c CYTOS BIOTECHNOLOGY AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTYROSINE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; RETROVIRUS VECTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ARTICLE; BREAST TUMOR; CELL CYCLE; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DIMERIZATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; ONCOGENE; ONCOGENE ERBB2; ONCOGENE ERBB3; PRIORITY JOURNAL; VESICULAR STOMATITIS VIRUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BREAST NEOPLASMS; CELL DIVISION; DIMERIZATION; FEMALE; GENE EXPRESSION; GENES, ERBB; GENES, ERBB-2; HUMANS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION;

UNIDENTIFIED RETROVIRUS; VESICULAR STOMATITIS VIRUS;

EID: 0042307325     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1537685100     Document Type: Article

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