Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1α promoter

Gene Therapy

Volumn 8, Issue 20, 2001, Pages 1539-1546

  Gill, D R ^a   Smyth, S E ^a   Goddard, C A ^b   Pringle, I A ^d   Higgins, C F ^c   Colledge, W H ^b   Hyde, S C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

^d NONE

Author keywords

Elongation factor 1 promoter; Gene transfer; Lung gene expression; Naked DNA; Ubiquitin C promoter

Indexed keywords

ANTIGEN; ELONGATION FACTOR 1ALPHA; PLASMID DNA; POLYUBIQUITIN;

ADENOVIRUS; AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; ATTENUATION; CHRONIC DISEASE; CLINICAL STUDY; CONTROLLED STUDY; CYSTIC FIBROSIS; CYTOMEGALOVIRUS; DNA VECTOR; DRUG EFFICACY; EXPERIMENTAL MODEL; FEMALE; GENE ACTIVITY; GENE EXPRESSION; GENE SILENCING; GENE THERAPY; GENE TRANSFER; IN VIVO STUDY; LUNG; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; ROUS SARCOMA ONCOVIRUS; SIMIAN VIRUS 40; TRANSGENE;

ADMINISTRATION, INHALATION; ANIMALS; AVIAN SARCOMA VIRUSES; CELL LINE; CYSTIC FIBROSIS; CYTOMEGALOVIRUS; FEMALE; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; HUMANS; LUCIFERASES; LUNG; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; PEPTIDE ELONGATION FACTOR 1; PLASMIDS; PROMOTER REGIONS (GENETICS); SIMIAN VIRUS 40; STATISTICS, NONPARAMETRIC; TIME FACTORS; TRANSGENES; UBIQUITIN C;

EID: 0035166381     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301561     Document Type: Article

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