Pharmacogenetics: Implications for obstetric anesthesia

International Journal of Obstetric Anesthesia

Volumn 14, Issue 4, 2005, Pages 316-323

  Landau, Ruth ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; ATENOLOL; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CD4 ANTIGEN; CODEINE; CORTICOSTEROID; CYTOCHROME P450; DIAMORPHINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FENTANYL; G PROTEIN COUPLED RECEPTOR; GLYCOPROTEIN P; ISOPRENALINE; METHADONE; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; OPIATE; PHENYLEPHRINE; RYANODINE RECEPTOR; SALBUTAMOL; TERBUTALINE;

AMINO ACID SUBSTITUTION; ANALGESIA; ASTHMA; DOWN REGULATION; DRUG METABOLISM; ETHNIC DIFFERENCE; GENE DELETION; GENE FREQUENCY; GENE LOCUS; GENETIC VARIABILITY; GENOTYPE; HEART INFARCTION; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HYPERTENSION; NAUSEA AND VOMITING; OBSTETRIC ANESTHESIA; PAIN; PHARMACODYNAMICS; PHARMACOGENETICS; PROTEIN EXPRESSION; RECEPTOR BLOCKING; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM;

ANESTHESIA, OBSTETRICAL; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HUMANS; NITRIC OXIDE SYNTHASE; PHARMACOGENETICS; PHARMACOKINETICS; POLYMORPHISM, GENETIC; PREGNANCY; RECEPTORS, ADRENERGIC; RECEPTORS, OPIOID;

EID: 26244448340     PISSN: 0959289X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijoa.2005.03.005     Document Type: Review

References (84)

1. W. Kalow, and D.R. Gunn The relation between dose of succinylcholine and duration of apnea in man J Pharmacol Exp Ther 120 1957 203 214
2. R. Sachidanandam, D. Weissman, and S.C. Schmidt A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms Nature 409 2001 928 933
3. A.J. Wood Ethnic differences in drug disposition and response Ther Drug Monit 20 1998 525 526
4. W.E. Evans, and J.A. Johnson Pharmacogenomics: the inherited basis for interindividual differences in drug response Annu Rev Genomics Hum Genet 2 2001 9 39
5. R. Weinshilboum Inheritance and drug response N Engl J Med 348 2003 529 537
6. W.E. Evans, and H.L. McLeod Pharmacogenomics drug disposition, drug targets, and side effects N Engl J Med 348 2003 538 549
7. T. Girard, S. Treves, E. Voronkov, M. Siegemund, and A. Urwyler Molecular genetic testing for malignant hyperthermia susceptibility Anesthesiology 100 2004 1076 1080
8. S.L. Kirstein, and P.A. Insel Autonomic nervous system pharmacogenomics: a progress report Pharmacol Rev 56 2004 31 52
9. L.S. Stone, L.B. MacMillan, K.F. Kitto, L.E. Limbird, and G.L. Wilcox The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy J Neurosci 17 1997 7157 7165
10. J.W. Kable, L.C. Murrin, and D.B. Bylund In vivo gene modification elucidates subtype-specific functions of alpha (2)-adrenergic receptors J Pharmacol Exp Ther 293 2000 1 7
11. R.E. Link, K. Desai, and L. Hein Cardiovascular regulation in mice lacking alpha2-adrenergic receptor subtypes b and c Science 273 1996 803 805
12. M. Holmberg, V. Fagerholm, and M. Scheinin Regional distribution of alpha(2C)-adrenoceptors in brain and spinal cord of control mice and transgenic mice overexpressing the alpha(2C)-subtype: an autoradiographic study with [(3)H]RX821002 and [(3)H]rauwolscine Neuroscience 117 2003 875 898
13. L. Hein, J.D. Altman, and B.K. Kobilka Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission Nature 402 1999 181 184
14. K.M. Small, S.L. Forbes, F.F. Rahman, K.M. Bridges, and S.B. Liggett A four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectors J Biol Chem 275 2000 23059 23064
15. K.M. Small, L.E. Wagoner, A.M. Levin, S.L. Kardia, and S.B. Liggett Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure N Engl J Med 347 2002 1135 1142
16. P. Heinonen, L. Jartti, and M.J. Jarvisalo Deletion polymorphism in the alpha2B-adrenergic receptor gene is associated with flow-mediated dilatation of the brachial artery Clin Sci (Lond) 103 2002 517 524
17. A. Snapir, J. Koskenvuo, and J. Toikka Effects of common polymorphisms in the alpha1A-, alpha2B-, beta1- and beta2-adrenoreceptors on haemodynamic responses to adrenaline Clin Sci (Lond) 104 2003 509 520
18. A. Snapir, J. Mikkelsson, M. Perola, A. Penttila, M. Scheinin, and P.J. Karhunen Variation in the alpha2B-adrenoceptor gene as a risk factor for prehospital fatal myocardial infarction and sudden cardiac death J Am Coll Cardiol 41 2003 190 194
19. A. Snapir, P. Heinonen, and T.P. Tuomainen An insertion/deletion polymorphism in the alpha2B-adrenergic receptor gene is a novel genetic risk factor for acute coronary events J Am Coll Cardiol 37 2001 1516 1522
20. D.A. Mason, J.D. Moore, S.A. Green, and S.B. Liggett A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor J Biol Chem 274 1999 12670 12674
21. G.G. Sofowora, V. Dishy, and M. Muszkat A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade Clin Pharmacol Ther 73 2003 366 371
22. H.G. Xie, V. Dishy, and G. Sofowora Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo Pharmacogenetics 11 2001 191 197
23. S.B. Liggett Polymorphisms of the beta2-adrenergic receptor N Engl J Med 346 2002 536 538
24. S.A. Green, J. Turki, M. Innis, and S.B. Liggett Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonist-promoted regulatory properties Biochemistry 33 1994 9414 9419
25. J.J. Lima, D.B. Thomason, M.H. Mohamed, L.V. Eberle, T.H. Self, and J.A. Johnson Impact of genetic polymorphisms of the beta2-adrenergic receptor on albuterol bronchodilator pharmacodynamics Clin Pharmacol Ther 65 1999 519 525
26. E. Israel, V.M. Chinchilli, and J.G. Ford Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial Lancet 364 2004 1505 1512
27. R. Landau, H.G. Xie, and V. Dishy beta2-Adrenergic receptor genotype and preterm delivery Am J Obstet Gynecol 187 2002 1294 1298
28. K. Doh, I. Sziller, S. Vardhana, E. Kovacs, Z. Papp, and S.S. Witkin Beta2-adrenergic receptor gene polymorphisms and pregnancy outcome J Perinat Med 32 2004 413 417
29. R. Landau, M. Morales, and S. Antonarakis Genotype of the B2 adrenergic receptor determines response to tocolysis Anesthesiology 98 suppl 1 2003 10
30. A. Busjahn, G.H. Li, and H.D. Faulhaber beta-2 adrenergic receptor gene variations, blood pressure, and heart size in normal twins Hypertension 35 2000 555 560
31. J.R. Cockcroft, A.G. Gazis, and D.J. Cross Beta (2)-adrenoceptor polymorphism determines vascular reactivity in humans Hypertension 36 2000 371 375
32. V. Dishy, G.G. Sofowora, and H.G. Xie The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization N Engl J Med 345 2001 1030 1035
33. B.D. Hoit, D.P. Suresh, L. Craft, R.A. Walsh, and S.B. Liggett beta2-adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals Am Heart J 139 2000 537 542
34. S.B. Liggett, L.E. Wagoner, and L.L. Craft The Ile164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure J Clin Invest 102 1998 1534 1539
35. O.E. Brodde, R. Buscher, and R. Tellkamp Blunted cardiac responses to receptor activation in subjects with Thr164Ile beta (2)-adrenoceptors Circulation 103 2001 1048 1050
36. V. Dishy, R. Landau, and G.G. Sofowora beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo Pharmacogenetics 14 2004 517 522
37. K. Leineweber, and O.E. Brodde Beta2-adrenoceptor polymorphisms: relation between in vitro and in vivo phenotypes Life Sci 74 2004 2803 2814
38. G. Alvan, P. Bechtel, L. Iselius, and U. Gundert-Remy Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations Eur J Clin Pharmacol 39 1990 533 537
39. D.G. Williams, A. Patel, and R.F. Howard Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability Br J Anaesth 89 2002 839 845
40. P. Dayer, J. Desmeules, T. Leemann, and R. Striberni Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI) Biochem Biophys Res Commun 152 1988 411 416
41. J. Desmeules, M.P. Gascon, P. Dayer, and M. Magistris Impact of environmental and genetic factors on codeine analgesia Eur J Clin Pharmacol 41 1991 23 26
42. S.H. Sindrup, and K. Brosen The pharmacogenetics of codeine hypoalgesia Pharmacogenetics 5 1995 335 346
43. K. Eckhardt, S. Li, S. Ammon, G. Schanzle, G. Mikus, and M. Eichelbaum Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation Pain 76 1998 27 33
44. Y. Gasche, Y. Daali, and M. Fathi Codeine intoxication associated with ultrarapid CYP2D6 metabolism N Engl J Med 351 2004 2827 2831
45. C. Gaveriaux-Ruff, and B.L. Kieffer Opioid receptor genes inactivated in mice: the highlights Neuropeptides 36 2002 62 71
46. B.L. Kieffer, and C. Gaveriaux-Ruff Exploring the opioid system by gene knockout Prog Neurobiol 66 2002 285 306
47. J.S. Mogil The genetic mediation of individual differences in sensitivity to pain and its inhibition Proc Natl Acad Sci U S A 96 1999 7744 7751
48. G.W. Pasternak The pharmacology of mu analgesics: from patients to genes Neuroscientist 7 2001 220 231
49. G.R. Uhl, I. Sora, and Z. Wang The mu opiate receptor as a candidate gene for pain: polymorphisms, variations in expression, nociception, and opiate responses Proc Natl Acad Sci U S A 96 1999 7752 7755
50. S. Grosch, E. Niederberger, and J. Lotsch A rapid screening method for a single nucleotide polymorphism (SNP) in the human MOR gene Br J Clin Pharmacol 52 2001 711 714
51. K.S. LaForge, V. Shick, and R. Spangler Detection of single nucleotide polymorphisms of the human mu opioid receptor gene by hybridization or single nucleotide extension on custom oligonucleotide gelpad microchips: potential in studies of addiction Am J Med Genet 96 2000 604 615
52. J. Gelernter, H. Kranzler, and J. Cubells Genetics of two mu opioid receptor gene (OPRM1) exon I polymorphisms: population studies, and allele frequencies in alcohol- and drug-dependent subjects Mol Psychiatry 4 1999 476 483
53. C. Bond, K.S. LaForge, and M. Tian Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction Proc Natl Acad Sci U S A 95 1998 9608 9613
54. E.C. Tan, C.H. Tan, U. Karupathivan, and E.P. Yap Mu opioid receptor gene polymorphisms and heroin dependence in Asian populations Neuroreport 14 2003 569 572
55. J.J. Crowley, D.W. Oslin, and A.A. Patkar A genetic association study of the mu opioid receptor and severe opioid dependence Psychiatr Genet 13 2003 169 173
56. J. Lotsch, C. Skarke, S. Grosch, J. Darimont, H. Schmidt, and G. Geisslinger The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine Pharmacogenetics 12 2002 3 9
57. J. Lotsch, M. Zimmermann, and J. Darimont Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity Anesthesiology 97 2002 814 819
58. P. Klepstad, T.T. Rakvag, and S. Kaasa The 118 A > G polymorphism in the human micro-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease Acta Anaesthesiol Scand 48 2004 1232 1239
59. C.A. Hernandez-Avila, G. Wand, X. Luo, J. Gelernter, and H.R. Kranzler Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1 Am J Med Genet 118B 2003 60 65
60. G.S. Wand, M. McCaul, and X. Yang The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockade Neuropsychopharmacology 26 2002 106 114
61. R. Landau, A. Cahana, R.M. Smiley, S.E. Antonarakis, and J.L. Blouin Genetic variability of mu-opioid receptor in an obstetric population Anesthesiology 100 2004 1030 1033
62. I. Belfer, T. Wu, A. Kingman, R.K. Krishnaraju, D. Goldman, and M.B. Max Candidate gene studies of human pain mechanisms: methods for optimizing choice of polymorphisms and sample size Anesthesiology 100 2004 1562 1572
63. J.C. Eisenach Fishing for genes: practical ways to study genetic polymorphisms for pain Anesthesiology 100 2004 1343 1344
64. J.P. Casas, L.E. Bautista, S.E. Humphries, and A.D. Hingorani Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects Circulation 109 2004 1359 1365
65. K. Chang, S.H. Baek, and K.B. Seung The Glu298Asp polymorphism in the endothelial nitric oxide synthase gene is strongly associated with coronary spasm Coron Artery Dis 14 2003 293 299
66. G.P. Rossi, M. Cesari, and M. Zanchetta The T-786C endothelial nitric oxide synthase genotype is a novel risk factor for coronary artery disease in Caucasian patients of the GENICA study J Am Coll Cardiol 41 2003 930 937
67. M.G. Colombo, U. Paradossi, and M.G. Andreassi Endothelial nitric oxide synthase gene polymorphisms and risk of coronary artery disease Clin Chem 49 2003 389 395
68. A.D. Hingorani Endothelial nitric oxide synthase polymorphisms and hypertension Curr Hypertens Rep 5 2003 19 25
69. M. Shoji, S. Tsutaya, R. Saito, H. Takamatu, and M. Yasujima Positive association of endothelial nitric oxide synthase gene polymorphism with hypertension in northern Japan Life Sci 66 2000 2557 2562
70. A.V. Benjafield, and B.J. Morris Association analyses of endothelial nitric oxide synthase gene polymorphisms in essential hypertension Am J Hypertens 13 2000 994 998
71. Y. Miyamoto, Y. Saito, and N. Kajiyama Endothelial nitric oxide synthase gene is positively associated with essential hypertension Hypertension 32 1998 3 8
72. J.A. Lade, E.K. Moses, and G. Guo The eNOS gene: a candidate for the preeclampsia susceptibility locus Hypertens Pregnancy 18 1999 81 93
73. T. Yoshimura, M. Yoshimura, and A. Tabata Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with severe preeclampsia J Soc Gynecol Investig 7 2000 238 241
74. T. Yoshimura, M. Yoshimura, A. Tabata, H. Yasue, and H. Okamura The missense Glu298Asp variant of the endothelial nitric oxide synthase gene is strongly associated with placental abruption Hum Genet 108 2001 181 183
75. G. Kobashi, H. Yamada, and K. Ohta Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy Am J Med Genet 103 2001 241 244
76. C.B. Tempfer, S. Jirecek, and E.K. Riener Polymorphisms of thrombophilic and vasoactive genes and severe preeclampsia: a pilot study J Soc Gynecol Investig 11 2004 227 231
77. N.C. Serrano, J.P. Casas, and L.A. Diaz Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study Hypertension 44 2004 702 707
78. T. Hakli, E.L. Romppanen, M. Hiltunen, S. Helisalmi, K. Punnonen, and S. Heinonen Endothelial nitric oxide synthase polymorphism in preeclampsia J Soc Gynecol Investig 10 2003 154 157
79. T. Yoshimura, F.A. Chowdhury, M. Yoshimura, and H. Okamura Genetic and environmental contributions to severe preeclampsia: lack of association with the endothelial nitric oxide synthase Glu298Asp variant in a developing country Gynecol Obstet Invest 56 2003 10 13
80. R. Landau, H.G. Xie, V. Dishy, A.J. Wood, C.M. Stein, and R.M. Smiley No association of, the Asp298 variant of the endothelial nitric oxide synthase gene with preeclampsia Am J Hypertens 17 2004 391 394
81. M.D. Savvidou, P.J. Vallance, K.H. Nicolaides, and A.D. Hingorani Endothelial nitric oxide synthase gene polymorphism and maternal vascular adaptation to pregnancy Hypertension 38 2001 1289 1293
82. I. Philip, G. Plantefeve, and S. Vuillaumier-Barrot G894T polymorphism in the endothelial nitric oxide synthase gene is associated with an enhanced vascular responsiveness to phenylephrine Circulation 99 1999 3096 3098
83. R. Landau, M. Negron, and J.L. Blouin Effect of eNOS genetic polymorphism on hypotension and treatment response during spinal anesthesia for cesarean section Anesthesiology 100 Suppl 2004 A52
84. J. Kirchheiner, L. Bertilsson, H. Bruus, A. Wolff, I. Roots, and M. Bauer Individualized medicine - implementation of pharmacogenetic diagnostics in antidepressant drug treatment of major depressive disorders Pharmacopsychiatry 36 Suppl 3 2003 S235 S243