Endothelial nitric oxide synthase gene polymorphism and maternal vascular adaptation to pregnancy

Hypertension

Volumn 38, Issue 6, 2001, Pages 1289-1293

  Savvidou, Makrina D ^a   Vallance, Patrick J T ^b   Nicolaides, Kypros H ^a   Hingorani, Aroon D ^b  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Endothelium; Nitric oxide synthase; Pregnancy

Indexed keywords

DNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ADAPTATION; ADULT; ARTICLE; BRACHIAL ARTERY; FEMALE; FIRST TRIMESTER PREGNANCY; GENETIC POLYMORPHISM; GESTATIONAL AGE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MATERNAL HYPERTENSION; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; ULTRASOUND; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 0035674633     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/hy1201.097305     Document Type: Article

References (40)

1. Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium
2. Nitric oxide: An endogenous modulator of leukocyte adhesion
3. Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells
4. Nitric oxide-generating vasodilators and 8-bromocyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
5. Inhibition of low-density lipoprotein oxidation by nitric oxide: Potential role in atherogenesis
6. Basal nitric oxide synthesis in essential hypertension
7. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits
8. Endothelium dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction
9. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
10. Flow-mediated vasodilatation is enhanced in normal pregnancy but reduced in preeclampsia
11. The role of nitric oxide in the pathogenesis of preeclampsia
12. 298→Asp) is a major risk factor for coronary artery disease in the UK
13. Endothelial nitric oxide synthase gene is positively associated with essential hypertension
14. Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction
15. Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction
16. Association of the polymorphism of the endothelial constitutive nitric oxide synthase gene with myocardial infarction in the Japanese population
17. Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with severe preeclampsia
18. Intracellular processing of endothelial constitutive nitric oxide synthase isoforms associated with differences in severity of cardiopulmonary diseases: Cleavage of proteins with aspartase vs. glutamate at position 298
19. Serial study of factors influencing changes in cardiac output during human pregnancy
20. Twenty-four-hour ambulatory blood pressure measurement in a primigravid population
21. Identification of increased nitric oxide biosynthesis during pregnancy in rats
22. Nitric oxide-mediated vasodilation in human pregnancy
23. Urinary excretion of cyclic 3′,5′-adenosine monophosphate and cyclic 3′,5′-guanosine monophosphate during and after pregnancy
24. Induction of calcium-dependent nitric oxide synthases by sex hormones
25. Induction of nitric oxide synthases early in pregnancy
26. Non-invasive assessment of endothelial function in normal pregnancy
27. Normal pregnancy is associated with enhanced endothelium-dependent flow mediated vasodilation
28. Modulation of endothelium-dependent flow-mediated dilatation of the brachial artery by sex and menstrual cycle
29. Impaired vascular reactivity in insulin-dependent diabetes mellitus is related to disease duration and low density lipoprotein cholesterol levels
30. G894T polymorphism in the endothelial nitric oxide synthase gene is associated with an enhanced vascular responsiveness to phenylephrine
31. Preeclampsia: More than pregnancy-induced hypertension
32. Pathogenesis of preeclampsia: A comprehensive model
33. The value of the angiotensin sensitivity test in the early diagnosis of hypertensive disorders in pregnancy
34. Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of preeclampsia
35. Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension, proteinuria, thrombocytopenia, and intrauterine growth retardation
36. Genetic and familial predisposition to eclampsia and preeclampsia in a defined population
37. The incidence of severe preeclampsia amongst mothers and mothers-in-law of preeclamptics and controls
38. Evidence for a familial pregnancy-induced hypertension locus in the eNOS-gene region
39. Genetic susceptibility to preeclampsia and chromosome 7q36