Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability

British Journal of Anaesthesia

Volumn 89, Issue 6, 2002, Pages 839-845

  Williams, D G ^a,b   Patel, A ^c   Howard, R F ^d  

^a ROYAL LONDON HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ROYAL NATIONAL THROAT NOSE AND EAR HOSPITAL   (United Kingdom)

^d GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

Analgesia, genetic factors; Analgesics opioid, codeine; Enzymes, cytochrome P450 CYP2D6; Surgery, adenotonsillectomy

Indexed keywords

ANALGESIC AGENT; CODEINE; CYTOCHROME P450 2D6; DICLOFENAC; MORPHINE; PARACETAMOL;

ADENOTONSILLECTOMY; ANALGESIA; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DOCUMENTATION; PAIN ASSESSMENT; PHARMACOGENETICS; POPULATION RESEARCH; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELIABILITY; SCORING SYSTEM; TIME; URBAN AREA; VOMITING;

EID: 0036898460     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aef284     Document Type: Article

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