Ethnic differences in drug disposition and response

Therapeutic Drug Monitoring

Volumn 20, Issue 5, 1998, Pages 525-526

  Wood, Alastair J J ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Drug response; Ethnicity; Pharmacodynamics; Pharmacokinetics

Indexed keywords

DRUG;

CARDIOVASCULAR RESPONSE; CONFERENCE PAPER; DRUG DISPOSITION; DRUG METABOLISM; DRUG RESPONSE; ETHNIC DIFFERENCE; HUMAN; INDIVIDUALIZATION; PRIORITY JOURNAL; RACE DIFFERENCE;

CONTINENTAL POPULATION GROUPS; HUMANS; PHARMACOGENETICS; PHARMACOKINETICS;

EID: 0031692449     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-199810000-00013     Document Type: Conference Paper

References (11)

1. Wood AJ, Zhou HH. Ethnic differences in drug disposition and responsiveness. Clin Pharmacokinet 1991;20:350-73.
2. Zhou HH, Koshakji RP, Silberstein DJ, et al. Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites. New Engl J Med 1989;320:565-70.
3. Zhou HH, Wood AJJ. Differences in stereoselective disposition of propranolol do not explain sensitivity differences between white and Chinese subjects: Correlation between the clearance of (-)- and (+)- propranolol. Clin Pharmacol Ther 1990;47:719-23.
4. Zhou HH, Wood AJ. Increased suppression of exercise-induced increase in renin by propranolol in Chinese subjects. Clin Pharmacol Ther 1991;50:150-56.
5. Zhou HH, Sheller JR, Nu H, et al. Ethnic differences in response to morphine. Clin Pharmacol Ther 1993;54:507-13.
6. Kinirons MT, Lang CC, He HB, et al. Triazolam pharmacokinetics and pharmacodynamics in Caucasians and Southern Asians: Ethnicity and CYP3A activity. Br J Clin Pharmacol 1996;41:69-72.
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8. Ahsan CH, Renwick AG, Waller DG, et al. The influence of dose and ethnic origins on the pharmacokinetics of nifedipine. Clin Pharmacol Ther 1993;54:329-38.
9. Lang CC, Stein CM, Brown RM, et al. Attenuation of isoproterenol-mediated vasodilation in blacks. New Engl J Med 1995;333: 155-60.
10. Stein CM, Lang CC, Nelson R, et al. Vasodilation in black Americans: attenuated nitric oxide-mediated responses. Clin Pharmacol Ther 1997;62:436-43.
11. Caraco Y, Sheller J, Wood AJJ. The impact of ethnic origin and quinidine coadministration on codeine's disposition and pharmacodynamic effects. 1998;(submitted).