Dieldrin induces ubiquitin-proteasome dysfunction in α-synuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death

Journal of Pharmacology and Experimental Therapeutics

Volumn 315, Issue 1, 2005, Pages 69-79

  Sun, Faneng ^a   Anantharam, Vellareddy ^a   Latchoumycandane, Calivarathan ^a   Kanthasamy, Arthi ^a   Kanthasamy, Anumantha G ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; BIOCHEMICAL MARKER; CADAVERINE; CASPASE 3; DIELDRIN; DNA FRAGMENT; PESTICIDE; PROTEASOME; UBIQUITIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOT HYBRIDIZATION; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; EXPRESSION VECTOR; GENE OVEREXPRESSION; LYSOSOME; MESENCEPHALON; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; OLIGOMERIZATION; PHAGOSOME; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; WILD TYPE;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELL LINE; DIELDRIN; DNA FRAGMENTATION; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; INSECTICIDES; NEURONS; OXIDATIVE STRESS; PARKINSONIAN DISORDERS; PHAGOSOMES; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; UBIQUITIN;

EID: 25644446864     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.105.084632     Document Type: Article

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