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Volumn 60, Issue 9, 2005, Pages 1125-1131

Dietary restriction in the nematode Caenorhabditis elegans

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; SOMATOMEDIN C; TARGET OF RAPAMYCIN KINASE;

EID: 25644432048     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/60.9.1125     Document Type: Review
Times cited : (49)

References (81)
  • 1
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of life and upon ultimate size
    • McCay C, Crowell M, Maynard L. The effect of retarded growth upon the length of life and upon ultimate size. J Nutr. 1935;10:63-79.
    • (1935) J Nutr , vol.10 , pp. 63-79
    • McCay, C.1    Crowell, M.2    Maynard, L.3
  • 2
    • 0033738362 scopus 로고    scopus 로고
    • An intervention resembling caloric restriction prolongs life span and retards aging in yeast
    • Jiang JC, Jaruga E, Repnevskaya MV, Jazwinski SM. An intervention resembling caloric restriction prolongs life span and retards aging in yeast. FASEB J. 2000;14:2135-2137.
    • (2000) FASEB J , vol.14 , pp. 2135-2137
    • Jiang, J.C.1    Jaruga, E.2    Repnevskaya, M.V.3    Jazwinski, S.M.4
  • 3
    • 0027880487 scopus 로고
    • Phenotypic plasticity and selection in Drosophila life history evolution. I. Nutrition and the cost of reproduction
    • Chippindale AK, Leroi A, Kim SB, Rose MR. Phenotypic plasticity and selection in Drosophila life history evolution. I. Nutrition and the cost of reproduction. J Evol Biol. 1993;6:171-193.
    • (1993) J Evol Biol , vol.6 , pp. 171-193
    • Chippindale, A.K.1    Leroi, A.2    Kim, S.B.3    Rose, M.R.4
  • 4
    • 0030463128 scopus 로고    scopus 로고
    • Female fitness in Drosophila melanogaster: An interaction between the effect of nutrition and of encounter rate with males
    • Chapman T, Partridge L. Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males. Proc R Soc Land B. 1996;263:755-759.
    • (1996) Proc R Soc Land B , vol.263 , pp. 755-759
    • Chapman, T.1    Partridge, L.2
  • 5
    • 0029684517 scopus 로고    scopus 로고
    • Caloric restriction and aging
    • Weindruch R. Caloric restriction and aging. Sci Am. 1996;274:46-52.
    • (1996) Sci Am , vol.274 , pp. 46-52
    • Weindruch, R.1
  • 7
    • 0037111862 scopus 로고    scopus 로고
    • Caloric restriction and aging in primates: Relevance to humans and possible CR mimetics
    • Lane M, Mattison J, Ingram D, Roth G. Caloric restriction and aging in primates: relevance to humans and possible CR mimetics. Microsc Res Tech. 2002;59:335-338.
    • (2002) Microsc Res Tech , vol.59 , pp. 335-338
    • Lane, M.1    Mattison, J.2    Ingram, D.3    Roth, G.4
  • 8
    • 2442428282 scopus 로고    scopus 로고
    • Effects of long-term diet restriction on aging and longevity in primates remain uncertain
    • Lane M, Mattison J, Roth G, Brant L, Ingram D. Effects of long-term diet restriction on aging and longevity in primates remain uncertain. J Gerontol A Biol Sci Med Sci. 2004;59:405-407.
    • (2004) J Gerontol A Biol Sci Med Sci , vol.59 , pp. 405-407
    • Lane, M.1    Mattison, J.2    Roth, G.3    Brant, L.4    Ingram, D.5
  • 9
    • 13944282128 scopus 로고    scopus 로고
    • Sex and death: What is the connection?
    • Partridge L, Gems D, Withers DJ. Sex and death: what is the connection? Cell. 2005;120:461-472.
    • (2005) Cell , vol.120 , pp. 461-472
    • Partridge, L.1    Gems, D.2    Withers, D.J.3
  • 10
    • 0024655426 scopus 로고
    • Food, reproduction and longevity: Is the extended lifespan of calorie-restricted animals an evolutionary adaptation?
    • Holliday R. Food, reproduction and longevity: is the extended lifespan of calorie-restricted animals an evolutionary adaptation? Bioessays. 1989;10:125-127.
    • (1989) Bioessays , vol.10 , pp. 125-127
    • Holliday, R.1
  • 11
    • 0029848121 scopus 로고    scopus 로고
    • The evolution of the antiaging action of dietary restriction: A hypothesis
    • Masoro EJ, Austad SN. The evolution of the antiaging action of dietary restriction: a hypothesis. J Gerontol A Biol Sci Med Sci. 1996;51B:387-391.
    • (1996) J Gerontol A Biol Sci Med Sci , vol.51 B , pp. 387-391
    • Masoro, E.J.1    Austad, S.N.2
  • 12
    • 0033910956 scopus 로고    scopus 로고
    • Calorie restriction and aging: A life-history analysis
    • Shanley DP, Kirkwood TB. Calorie restriction and aging: a life-history analysis. Evol Int J Org Evol. 2000;54:740-750.
    • (2000) Evol Int J Org Evol , vol.54 , pp. 740-750
    • Shanley, D.P.1    Kirkwood, T.B.2
  • 13
    • 0002639352 scopus 로고    scopus 로고
    • Feeding and defecation
    • Riddle DL, Blumenthal T, Meyer BJ, Priess JR, eds. Plainview, NY: Cold Spring Harbor Laboratory Press
    • Avery L, Thomas J. Feeding and defecation. In Riddle DL, Blumenthal T, Meyer BJ, Priess JR, eds. C. elegans 11. Plainview, NY: Cold Spring Harbor Laboratory Press; 1997:679-716.
    • (1997) C. Elegans 11 , pp. 679-716
    • Avery, L.1    Thomas, J.2
  • 14
    • 0022585682 scopus 로고
    • The autofluorescent "lipofuscin granules" in the intestinal cells of Caenorhabditis elegans are secondary lysosomes
    • Clokey GV, Jacobson LA. The autofluorescent "lipofuscin granules" in the intestinal cells of Caenorhabditis elegans are secondary lysosomes. Mech Ageing Dev. 1986;35:79-94.
    • (1986) Mech Ageing Dev , vol.35 , pp. 79-94
    • Clokey, G.V.1    Jacobson, L.A.2
  • 15
    • 0028225587 scopus 로고
    • Production of age-synchronous mass cultures of Caenorhabditis elegans
    • Fabian TJ, Johnson TE. Production of age-synchronous mass cultures of Caenorhabditis elegans. J Gerontol A Biol Sci Med Sci. 1994;49: B145-B156.
    • (1994) J Gerontol A Biol Sci Med Sci , vol.49
    • Fabian, T.J.1    Johnson, T.E.2
  • 16
    • 0036021375 scopus 로고    scopus 로고
    • Genetic analysis of tissue aging in Caenorhabditis elegans. A role for heat-shock factor and bacterial proliferation
    • Garigan D, Hsu AL, Fraser AG, Kamath RS, Ahringer J, Kenyon C. Genetic analysis of tissue aging in Caenorhabditis elegans. A role for heat-shock factor and bacterial proliferation. Genetics. 2002;161:1101-1112.
    • (2002) Genetics , vol.161 , pp. 1101-1112
    • Garigan, D.1    Hsu, A.L.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Kenyon, C.6
  • 17
    • 0034036321 scopus 로고    scopus 로고
    • Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans
    • Gems D, Riddle DL. Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans. Genetics. 2000;154:1597-1610.
    • (2000) Genetics , vol.154 , pp. 1597-1610
    • Gems, D.1    Riddle, D.L.2
  • 18
    • 0343693838 scopus 로고
    • Development and maturation of Caenorhabditis briggsae in response to growth factor
    • Hansen E, Buecher EJ, Yarwood EA. Development and maturation of Caenorhabditis briggsae in response to growth factor. Nematologica. 1964;10:623-630.
    • (1964) Nematologica , vol.10 , pp. 623-630
    • Hansen, E.1    Buecher, E.J.2    Yarwood, E.A.3
  • 19
    • 0017643661 scopus 로고
    • The aging process of the nematode Caenorhabditis elegans in bacterial and axenic culture
    • Croll NA, Smith JM, Zuckerman BM. The aging process of the nematode Caenorhabditis elegans in bacterial and axenic culture. Exp Aging Res. 1977;3:175-189.
    • (1977) Exp Aging Res , vol.3 , pp. 175-189
    • Croll, N.A.1    Smith, J.M.2    Zuckerman, B.M.3
  • 20
    • 0017763799 scopus 로고
    • Aging in the nematode Caenorhabditis elegans: Major biological and environmental factors influencing life span
    • Klass MR. Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span. Mech Ageing Dev. 1977;6:413-429.
    • (1977) Mech Ageing Dev , vol.6 , pp. 413-429
    • Klass, M.R.1
  • 21
    • 0024385843 scopus 로고    scopus 로고
    • Alterations of life-span in the nematode Caenorhabditis elegans under monoxenic culture conditions
    • Hosono R, Nishimoto S, Kuno S. Alterations of life-span in the nematode Caenorhabditis elegans under monoxenic culture conditions. Exp Gerontol. 1998;24:251-264.
    • (1998) Exp Gerontol , vol.24 , pp. 251-264
    • Hosono, R.1    Nishimoto, S.2    Kuno, S.3
  • 22
    • 0032573178 scopus 로고    scopus 로고
    • The genetics of caloric restriction in Caenorhabditis elegans
    • Lakowski B, Hekimi S. The genetics of caloric restriction in Caenorhabditis elegans. Proc Natl Acad Sci USA. 1998;95:13091-13096.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13091-13096
    • Lakowski, B.1    Hekimi, S.2
  • 23
    • 0013881593 scopus 로고
    • Ficoll activation of a protein essential for maturation of the free-living nematode Caenorhabditis briggsae
    • Buecher EJ, Hansen EL, Yarwood EA. Ficoll activation of a protein essential for maturation of the free-living nematode Caenorhabditis briggsae. Proc Soc Exp Biol Med. 1966;121:390-393.
    • (1966) Proc Soc Exp Biol Med , vol.121 , pp. 390-393
    • Buecher, E.J.1    Hansen, E.L.2    Yarwood, E.A.3
  • 24
    • 0000469502 scopus 로고
    • Axenic culture of free-living, plant-parasitic, and insect-parasitic nematodes
    • Vanfleteren JR. Axenic culture of free-living, plant-parasitic, and insect-parasitic nematodes. Ann Rev Phytopathol. 1978;16:131-157.
    • (1978) Ann Rev Phytopathol , vol.16 , pp. 131-157
    • Vanfleteren, J.R.1
  • 25
    • 0036975161 scopus 로고    scopus 로고
    • Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans
    • Houthoofd K, Braeckman BP, Lenaerts I, et al. Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans. Exp Gerontol. 2002;37:1371-1378.
    • (2002) Exp Gerontol , vol.37 , pp. 1371-1378
    • Houthoofd, K.1    Braeckman, B.P.2    Lenaerts, I.3
  • 27
    • 0042886011 scopus 로고    scopus 로고
    • Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans
    • Houthoofd K, Braeckman BP, Johnson TE, Vanfleteren JR. Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans. Exp Gerontol. 2003;38:947-954.
    • (2003) Exp Gerontol , vol.38 , pp. 947-954
    • Houthoofd, K.1    Braeckman, B.P.2    Johnson, T.E.3    Vanfleteren, J.R.4
  • 28
    • 85044703856 scopus 로고    scopus 로고
    • No reduction of metabolic rate in food restricted Caenorhabditis elegans
    • Houthoofd K, Braeckman BP, Lenaerts I, et al. No reduction of metabolic rate in food restricted Caenorhabditis elegans. Exp Gerontol. 2002;37:1359-1369.
    • (2002) Exp Gerontol , vol.37 , pp. 1359-1369
    • Houthoofd, K.1    Braeckman, B.P.2    Lenaerts, I.3
  • 29
    • 0037458617 scopus 로고    scopus 로고
    • Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span
    • Fei YJ, Inoue K, Ganapathy V. Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. J Biol Chem. 2003;278:6136-6144.
    • (2003) J Biol Chem , vol.278 , pp. 6136-6144
    • Fei, Y.J.1    Inoue, K.2    Ganapathy, V.3
  • 30
    • 1842844288 scopus 로고    scopus 로고
    • Relevance of Nac-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans
    • Fei YJ, Liu JC, Inoue K, et al. Relevance of Nac-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans. Biochem J. 2004;379:191-198.
    • (2004) Biochem J , vol.379 , pp. 191-198
    • Fei, Y.J.1    Liu, J.C.2    Inoue, K.3
  • 31
    • 4344632329 scopus 로고    scopus 로고
    • Deletion of the intestinal peptide transporter affects insulin and Tor signaling in Caenorhabditis elegans
    • MeissnerB, Boll M, Daniel H, Baumeister R. Deletion of the intestinal peptide transporter affects insulin and Tor signaling in Caenorhabditis elegans. J Biol Chem. 2004;279:36739-36745.
    • (2004) J Biol Chem , vol.279 , pp. 36739-36745
    • Meissner, B.1    Boll, M.2    Daniel, H.3    Baumeister, R.4
  • 32
    • 0242497750 scopus 로고    scopus 로고
    • A reduction in intestinal cell pHj due to loss of the Caenorhabditis elegans Na+/H+exchanger NHX-2 increases life span
    • Nehrke K. A reduction in intestinal cell pHj due to loss of the Caenorhabditis elegans Na+/H+exchanger NHX-2 increases life span. J Biol Chem. 2003;278:44657-44666.
    • (2003) J Biol Chem , vol.278 , pp. 44657-44666
    • Nehrke, K.1
  • 33
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol. 1956;11:298-300.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 34
    • 0041440219 scopus 로고    scopus 로고
    • A metabolic model for life span determination in Caenorhabditis elegans
    • Rea S, Johnson TE. A metabolic model for life span determination in Caenorhabditis elegans. Dev Cell. 2003;5:197-203.
    • (2003) Dev Cell , vol.5 , pp. 197-203
    • Rea, S.1    Johnson, T.E.2
  • 35
    • 0036828603 scopus 로고    scopus 로고
    • Molecular mechanisms linking calorie restriction and longevity
    • Merry BJ. Molecular mechanisms linking calorie restriction and longevity. Int J Biochem Cell Biol. 2002;34:1340-1354.
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1340-1354
    • Merry, B.J.1
  • 36
    • 0002982269 scopus 로고
    • Life table modifications and life prolongation
    • Finch CE, Hayflick L, eds. New York: Van Nostrand Reinhold
    • Sacher GA. Life table modifications and life prolongation. In: Finch CE, Hayflick L, eds. Handbook of the Biology of Aging. New York: Van Nostrand Reinhold; 1977;582-638.
    • (1977) Handbook of the Biology of Aging , pp. 582-638
    • Sacher, G.A.1
  • 38
    • 13944269026 scopus 로고    scopus 로고
    • Dietary restriction in C. elegans: From rate-of-living effects to nutrient sensing pathways
    • In press
    • Walker G, Houthoofd K, Vanfleteren JR, Gems D. Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways. Mech Aging Dev. 2005. In press.
    • (2005) Mech Aging Dev
    • Walker, G.1    Houthoofd, K.2    Vanfleteren, J.R.3    Gems, D.4
  • 39
    • 0029776793 scopus 로고    scopus 로고
    • Determination of life-span in Caenorhabditis elegans by four clock genes
    • Lakowski B, Hekimi S. Determination of life-span in Caenorhabditis elegans by four clock genes. Science. 1996;17:1010-1013.
    • (1996) Science , vol.17 , pp. 1010-1013
    • Lakowski, B.1    Hekimi, S.2
  • 40
    • 0028950419 scopus 로고
    • Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing
    • Wong A, Boutis P, Hekimi S. Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing. Genetics. 1995;139:1247-1259.
    • (1995) Genetics , vol.139 , pp. 1247-1259
    • Wong, A.1    Boutis, P.2    Hekimi, S.3
  • 41
    • 0036757226 scopus 로고    scopus 로고
    • No reduction of energy metabolism in Clk mutants
    • Braeckman BP, Houthoofd K, Brys K, et al. No reduction of energy metabolism in Clk mutants. Mech Ageing Dev. 2002;123:1447-1456.
    • (2002) Mech Ageing Dev , vol.123 , pp. 1447-1456
    • Braeckman, B.P.1    Houthoofd, K.2    Brys, K.3
  • 42
    • 0033529032 scopus 로고    scopus 로고
    • Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans
    • Braeckman BP, Houthoofd K, De Vreese A, Vanfleteren JR. Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans. Curr Biol. 1999;9:493-496.
    • (1999) Curr Biol , vol.9 , pp. 493-496
    • Braeckman, B.P.1    Houthoofd, K.2    De Vreese, A.3    Vanfleteren, J.R.4
  • 43
    • 0022375067 scopus 로고
    • The effects of aging and chronic dietary restriction on whole body growth and protein turnover in the rat
    • Lewis SE, Goldspink DF, Phillips JG, Merry BJ, Holehan AM. The effects of aging and chronic dietary restriction on whole body growth and protein turnover in the rat. Exp Gerontol. 1985;20:253-263.
    • (1985) Exp Gerontol , vol.20 , pp. 253-263
    • Lewis, S.E.1    Goldspink, D.F.2    Phillips, J.G.3    Merry, B.J.4    Holehan, A.M.5
  • 44
    • 0033788296 scopus 로고    scopus 로고
    • Metabolic mechanisms of yeast ageing
    • Jazwinski SM. Metabolic mechanisms of yeast ageing. Exp Gerontol. 2000;35:671-676.
    • (2000) Exp Gerontol , vol.35 , pp. 671-676
    • Jazwinski, S.M.1
  • 45
    • 0037130175 scopus 로고    scopus 로고
    • Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
    • Lin SJ, Kaeberlein M, Andalis AA, et al. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature. 2002;418:344-348.
    • (2002) Nature , vol.418 , pp. 344-348
    • Lin, S.J.1    Kaeberlein, M.2    Andalis, A.A.3
  • 46
    • 0030729851 scopus 로고    scopus 로고
    • High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
    • Korshunov SS, Skulachev VP, Starkov AA. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett. 1997:416:15-18.
    • (1997) FEBS Lett , vol.416 , pp. 15-18
    • Korshunov, S.S.1    Skulachev, V.P.2    Starkov, A.A.3
  • 47
    • 0033785071 scopus 로고    scopus 로고
    • Uncoupling to survive? The role of mitochondrial inefficiency in ageing
    • Brand MD. Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Exp Gerontol. 2000;35:811-820.
    • (2000) Exp Gerontol , vol.35 , pp. 811-820
    • Brand, M.D.1
  • 48
    • 4544264062 scopus 로고    scopus 로고
    • Mitochondrial membrane potential and aging
    • Nicholls DG. Mitochondrial membrane potential and aging. Aging Cell. 2004;3:35-40.
    • (2004) Aging Cell , vol.3 , pp. 35-40
    • Nicholls, D.G.1
  • 49
    • 7044239977 scopus 로고    scopus 로고
    • Uncoupled and surviving: Individual mice with high metabolism have greater mitochondrial uncoupling and live longer
    • Speakman JR, Talbot DA, Selman C, et al. Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. Aging Cell. 2004;3:87-95.
    • (2004) Aging Cell , vol.3 , pp. 87-95
    • Speakman, J.R.1    Talbot, D.A.2    Selman, C.3
  • 50
    • 0346455761 scopus 로고    scopus 로고
    • Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: Reversal by insulin
    • Lambert AJ, Merry BJ. Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin. Am J Physiol Regul Integr Comp Physiol. 2004;286:R71-R79.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Lambert, A.J.1    Merry, B.J.2
  • 51
    • 0031668348 scopus 로고    scopus 로고
    • Hormesis-Implications for risk assessment caloric intake (body weight) as an examplar
    • Turturro A, Hass B, Hart RW. Hormesis-Implications for risk assessment caloric intake (body weight) as an examplar. Hum Exp Toxicol. 1998;17:454-459.
    • (1998) Hum Exp Toxicol , vol.17 , pp. 454-459
    • Turturro, A.1    Hass, B.2    Hart, R.W.3
  • 52
    • 0031984854 scopus 로고    scopus 로고
    • Hormesis and the antiaging action of dietary restriction
    • Masoro EJ. Hormesis and the antiaging action of dietary restriction. Exp Gerontol. 1998;33:61-66.
    • (1998) Exp Gerontol , vol.33 , pp. 61-66
    • Masoro, E.J.1
  • 53
    • 15444371989 scopus 로고    scopus 로고
    • JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factior DAF-16
    • Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ, Tissenbaum HA. JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factior DAF-16. Proc Natl Acad Sci USA. 2005;102:4494-4499.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4494-4499
    • Oh, S.W.1    Mukhopadhyay, A.2    Svrzikapa, N.3    Jiang, F.4    Davis, R.J.5    Tissenbaum, H.A.6
  • 54
    • 0036245337 scopus 로고    scopus 로고
    • Mechanisms of ageing: Public or private?
    • Partridge L, Gems D. Mechanisms of ageing: public or private? Nat Rev Genet. 2002;3:165-175.
    • (2002) Nat Rev Genet , vol.3 , pp. 165-175
    • Partridge, L.1    Gems, D.2
  • 55
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature. 1993;366:461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 56
    • 0035846604 scopus 로고    scopus 로고
    • Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • Henderson ST, Johnson TE. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol. 2001;11:1975-1980.
    • (2001) Curr Biol , vol.11 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 57
    • 0042631524 scopus 로고    scopus 로고
    • Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
    • McElwee J, Bubb K, Thomas JH. Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell. 2003;2:111-121.
    • (2003) Aging Cell , vol.2 , pp. 111-121
    • McElwee, J.1    Bubb, K.2    Thomas, J.H.3
  • 58
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of Daf-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, et al. Genes that act downstream of Daf-16 to influence the lifespan of Caenorhabditis elegans. Nature. 2003;424:277-284.
    • (2003) Nature , vol.424 , pp. 277-284
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3
  • 59
    • 0033576579 scopus 로고    scopus 로고
    • Regulation of lifespan by sensory perception in Caenorhabditis elegans
    • Apfeld J, Kenyon C. Regulation of lifespan by sensory perception in Caenorhabditis elegans. Nature. 1999;402:804-809.
    • (1999) Nature , vol.402 , pp. 804-809
    • Apfeld, J.1    Kenyon, C.2
  • 60
    • 0035868890 scopus 로고    scopus 로고
    • Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family
    • Pierce SB, Costa M, Wisotzkey R, et al. Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Genes Dev. 2001;15:672-686.
    • (2001) Genes Dev , vol.15 , pp. 672-686
    • Pierce, S.B.1    Costa, M.2    Wisotzkey, R.3
  • 61
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
    • Libina N, Herman JR, Kenyon C. Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell. 2003;115:489-502.
    • (2003) Cell , vol.115 , pp. 489-502
    • Libina, N.1    Herman, J.R.2    Kenyon, C.3
  • 62
    • 0033609291 scopus 로고    scopus 로고
    • Signals from the reproductive system regulate the lifespan of C. elegans
    • Hsin H, Kenyon C. Signals from the reproductive system regulate the lifespan of C. elegans. Nature. 1999;399:362-366.
    • (1999) Nature , vol.399 , pp. 362-366
    • Hsin, H.1    Kenyon, C.2
  • 63
    • 0042721486 scopus 로고
    • Genetic variants and mutations of Caenorhabditis elegans provide tools for dissecting the aging process
    • Harrison D, ed. Caldwell, NJ: Telford
    • Johnson T, Friedman DB, Foltz N, Fitzpatrick PA, Shoemaker JE. Genetic variants and mutations of Caenorhabditis elegans provide tools for dissecting the aging process. In Harrison D, ed. Genetic Effects of Aging, Volume II. Caldwell, NJ: Telford; 1990;101-126.
    • (1990) Genetic Effects of Aging , vol.2 , pp. 101-126
    • Johnson, T.1    Friedman, D.B.2    Foltz, N.3    Fitzpatrick, P.A.4    Shoemaker, J.E.5
  • 66
    • 13644269577 scopus 로고    scopus 로고
    • DAF-2 pathway mutations and food restriction in aging Caenorhabditis elegans differentially affect metabolism
    • Houthoofd K, Braeckman BP, Lenaerts I, et al. DAF-2 pathway mutations and food restriction in aging Caenorhabditis elegans differentially affect metabolism. Near Biol Aging. 2005;26:689-696.
    • (2005) Near Biol Aging , vol.26 , pp. 689-696
    • Houthoofd, K.1    Braeckman, B.P.2    Lenaerts, I.3
  • 67
    • 0013404438 scopus 로고    scopus 로고
    • Interpreting interactions between treatments that slow aging
    • Gems D, Pletcher S, Partridge L. Interpreting interactions between treatments that slow aging. Aging Cell. 2002;1:1-9.
    • (2002) Aging Cell , vol.1 , pp. 1-9
    • Gems, D.1    Pletcher, S.2    Partridge, L.3
  • 70
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature. 2001;410:227-230.
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 71
    • 3943071801 scopus 로고    scopus 로고
    • Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • Wood JG, Rogina B, Lavu S, et al. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature. 2004;430:686-689.
    • (2004) Nature , vol.430 , pp. 686-689
    • Wood, J.G.1    Rogina, B.2    Lavu, S.3
  • 72
    • 0033214237 scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein M, McVey M, Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 1990;13:2570-2580.
    • (1990) Genes Dev , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 73
    • 0036599352 scopus 로고    scopus 로고
    • Regulation of lifespan by histone deacetylase
    • Chang KT, Min KT. Regulation of lifespan by histone deacetylase. Ageing Res Rev. 2002;1:313-326.
    • (2002) Ageing Res Rev , vol.1 , pp. 313-326
    • Chang, K.T.1    Min, K.T.2
  • 74
    • 0034703217 scopus 로고    scopus 로고
    • Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
    • Lin SJ, Defossez PA, Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science. 2000;289:2126-2128.
    • (2000) Science , vol.289 , pp. 2126-2128
    • Lin, S.J.1    Defossez, P.A.2    Guarente, L.3
  • 75
    • 10844236451 scopus 로고    scopus 로고
    • Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
    • Nemoto S, Fergusson MM, Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science. 2004;306:2105-2108.
    • (2004) Science , vol.306 , pp. 2105-2108
    • Nemoto, S.1    Fergusson, M.M.2    Finkel, T.3
  • 76
    • 0037306190 scopus 로고    scopus 로고
    • Insulin/IGF and target of rapamycin signaling: A TOR de force in growth control
    • Oldham S, Hafen E. Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol. 2003;13:79-85.
    • (2003) Trends Cell Biol , vol.13 , pp. 79-85
    • Oldham, S.1    Hafen, E.2
  • 77
    • 4544311861 scopus 로고    scopus 로고
    • The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
    • Jia K, Chen D, Riddle D. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development. 2004;131:3897-3906.
    • (2004) Development , vol.131 , pp. 3897-3906
    • Jia, K.1    Chen, D.2    Riddle, D.3
  • 79
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev. 2003;18:1926-1945.
    • (2003) Genes Dev , vol.18 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 80
    • 0037276069 scopus 로고    scopus 로고
    • A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway
    • Kimura N, Tokunaga C, Dalal S, et al. A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway. Genes Cells. 2003;8:65-79.
    • (2003) Genes Cells , vol.8 , pp. 65-79
    • Kimura, N.1    Tokunaga, C.2    Dalal, S.3
  • 81
    • 10644282295 scopus 로고    scopus 로고
    • The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
    • Apfeld J, O'Connor G, McDonagh T, DiStefano PS, Curtis R. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev. 2004;18:3004-3009.
    • (2004) Genes Dev , vol.18 , pp. 3004-3009
    • Apfeld, J.1    O'Connor, G.2    McDonagh, T.3    Distefano, P.S.4    Curtis, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.