Quantitative analysis of fluorescent caspase substrate cleavage in intact cells and identification of novel inhibitors of apoptosis

Cell Death and Differentiation

Volumn 8, Issue 1, 2001, Pages 30-37

  Tawa, P ^a   Tam, J ^a   Cassady, R ^a   Nicholson, D W ^a   Xanthoudakis, S ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

Apoptosis; Caspase activity; GFP

Indexed keywords

CASPASE; CASPASE 2; CASPASE 3; CASPASE 7; GREEN FLUORESCENT PROTEIN; RECOMBINANT PROTEIN;

ANALYSIS; APOPTOSIS; ARTICLE; BIOCHEMISTRY; CELL CULTURE; CELL DEATH; CELL LINE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG TARGETING; ENERGY TRANSFER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; FLUORESCENCE; HUMAN; HUMAN CELL; MEASUREMENT; MONITORING; MORPHOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE ASSAY; SCREENING; TECHNOLOGY;

APOPTOSIS; BIOLOGICAL ASSAY; CASPASE 3; CASPASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY TRANSFER; ENZYME ACTIVATION; ENZYME INHIBITORS; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; HYDROLYSIS; LUMINESCENT PROTEINS; PEPTIDE FRAGMENTS; POLY(ADP-RIBOSE) POLYMERASES; RECOMBINANT FUSION PROTEINS; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY;

EID: 0035135797     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400769     Document Type: Article

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