메뉴 건너뛰기




Volumn 23, Issue 6, 2005, Pages 746-751

A high-throughput assay for assessing the cell permeability of combinatorial libraries

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR DYNAMICS; OLIGOMERS; PROTEINS;

EID: 24944573100     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1099     Document Type: Article
Times cited : (92)

References (30)
  • 1
    • 0030995823 scopus 로고    scopus 로고
    • Residue-based control of helix shape in beta-peptide oligomers
    • Appella, D.H. et al. Residue-based control of helix shape in beta-peptide oligomers. Nature 387, 381-384 (1997).
    • (1997) Nature , vol.387 , pp. 381-384
    • Appella, D.H.1
  • 2
    • 0037450183 scopus 로고    scopus 로고
    • Design and synthesis of gamma-dipeptide derivatives with submicromolar affinities for human somatostatin receptors
    • Seebach, D., Schaeffer, L., Brenner, M. & Hoyer, D. Design and synthesis of gamma-dipeptide derivatives with submicromolar affinities for human somatostatin receptors. Angew. Chem. Int. Edn. Engl. 42, 776-778 (2003).
    • (2003) Angew. Chem. Int. Edn. Engl. , vol.42 , pp. 776-778
    • Seebach, D.1    Schaeffer, L.2    Brenner, M.3    Hoyer, D.4
  • 3
    • 0000908874 scopus 로고
    • Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis
    • Zuckermann, R.N., Kerr, J.M., Kent, S.B.H. & Moos, W.H. Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis. J. Am. Chem. Soc. 114, 10646-10647 (1992).
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 10646-10647
    • Zuckermann, R.N.1    Kerr, J.M.2    Kent, S.B.H.3    Moos, W.H.4
  • 5
    • 0025804183 scopus 로고
    • Correlation between oral drug absorption in humans and apparent drug permeability coefficients in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
    • Artursson, P. & Karlsson, J. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem. Biophys. Res. Commun. 175, 880-885 (1991).
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 880-885
    • Artursson, P.1    Karlsson, J.2
  • 6
    • 0031005057 scopus 로고    scopus 로고
    • Intestinal absorption screening of mixtures from combinatorial libraries in the Caco-2 model
    • Taylor, E.W., Gibbons, J.A. & Braeckman, R.A. Intestinal absorption screening of mixtures from combinatorial libraries in the Caco-2 model. Pharm. Res. 14, 572-577 (1997).
    • (1997) Pharm. Res. , vol.14 , pp. 572-577
    • Taylor, E.W.1    Gibbons, J.A.2    Braeckman, R.A.3
  • 7
    • 0035950120 scopus 로고    scopus 로고
    • Physicochemical determinants of passive membrane permeability: Role of solute hydrogen-bonding potential and volume
    • Goodwin, J.T., Conradi, R.A., Ho, N.F.H. & Burton, P.S. Physicochemical determinants of passive membrane permeability: Role of solute hydrogen-bonding potential and volume. J. Med. Chem. 44, 3721-3729 (2001).
    • (2001) J. Med. Chem. , vol.44 , pp. 3721-3729
    • Goodwin, J.T.1    Conradi, R.A.2    Ho, N.F.H.3    Burton, P.S.4
  • 8
    • 0033977587 scopus 로고    scopus 로고
    • Determination of in vitro permeability of drug candidates through a Caco-2 cell monolayer by liquid chromatography/tandem mass spectroscopy
    • Wang, Z., Hop, C.E.C.A., Leung, K.H. & Pang, J. Determination of in vitro permeability of drug candidates through a Caco-2 cell monolayer by liquid chromatography/tandem mass spectroscopy. J. Mass Spectrom. 35, 71-76 (2000).
    • (2000) J. Mass Spectrom. , vol.35 , pp. 71-76
    • Wang, Z.1    Hop, C.E.C.A.2    Leung, K.H.3    Pang, J.4
  • 9
    • 0042836926 scopus 로고    scopus 로고
    • Higher-throughput screening for Caco-2 permeability utilizing a multiple sprayer liquid chromatography/tandem mass spectrometry system
    • Fung, E.N. et al. Higher-throughput screening for Caco-2 permeability utilizing a multiple sprayer liquid chromatography/tandem mass spectrometry system. Rapid Commun. Mass Spectrom. 17, 2147-2152 (2003).
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , pp. 2147-2152
    • Fung, E.N.1
  • 10
    • 0034910022 scopus 로고    scopus 로고
    • Is VP22 nuclear homing an artifact?
    • Lundberg, M. & Johansson, M. Is VP22 nuclear homing an artifact? Nat. Biotechnol. 19, 713 (2001).
    • (2001) Nat. Biotechnol. , vol.19 , pp. 713
    • Lundberg, M.1    Johansson, M.2
  • 11
    • 0346460957 scopus 로고    scopus 로고
    • Cell-penetrating peptides: A reevaluation of the mechanism of cellular uptake
    • Richard, J.P. et al. Cell-penetrating peptides: A reevaluation of the mechanism of cellular uptake. J. Biol. Chem. 278, 585-590 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 585-590
    • Richard, J.P.1
  • 13
    • 0032004231 scopus 로고    scopus 로고
    • Heat shock protein interactions with the glucocorticoid receptor
    • Bertorelli, G., Bocchino, V. & Olivieri, D. Heat shock protein interactions with the glucocorticoid receptor. Pulm. Pharmacol. Ther. 11, 7-12 (1998).
    • (1998) Pulm. Pharmacol. Ther. , vol.11 , pp. 7-12
    • Bertorelli, G.1    Bocchino, V.2    Olivieri, D.3
  • 14
    • 0030925683 scopus 로고    scopus 로고
    • Steroid receptor interactions with heat shock protein and immunophilin chaperones
    • Pratt, W.B. & Toft, D.O. Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev. 18, 306-360 (1997).
    • (1997) Endocr. Rev. , vol.18 , pp. 306-360
    • Pratt, W.B.1    Toft, D.O.2
  • 15
    • 0032167985 scopus 로고    scopus 로고
    • A chimeric Cre recombinase inducible by synthetic, but not by natural ligands of the glucocorticoid receptor
    • Brocard, J., Feil, R., Chambon, P. & Metzger, D. A chimeric Cre recombinase inducible by synthetic, but not by natural ligands of the glucocorticoid receptor. Nucleic Acids Res. 26, 4086-4090 (1998).
    • (1998) Nucleic Acids Res , vol.26 , pp. 4086-4090
    • Brocard, J.1    Feil, R.2    Chambon, P.3    Metzger, D.4
  • 16
    • 0027465481 scopus 로고
    • A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins
    • Braselmann, S., Graninger, P. & Busslinger, M. A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins. Proc. Natl. Acad. Sci. USA 90, 1657-1661 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1657-1661
    • Braselmann, S.1    Graninger, P.2    Busslinger, M.3
  • 18
    • 0018765706 scopus 로고
    • 17β-carboxamide steroids are a new class of glucocorticoid antagonists
    • Rousseau, G.G. & Kirchhoff, J. 17β-Carboxamide steroids are a new class of glucocorticoid antagonists. Nature 279, 158-160 (1979).
    • (1979) Nature , vol.279 , pp. 158-160
    • Rousseau, G.G.1    Kirchhoff, J.2
  • 19
    • 85058199478 scopus 로고
    • Steroid side-chain modification and receptor affinity: Binding of synthetic derivatives of corticoids to human spleen tumor and rat liver glucocorticoid receptors
    • Manz, B., Grill, H-J. & Follow, K. Steroid side-chain modification and receptor affinity: Binding of synthetic derivatives of corticoids to human spleen tumor and rat liver glucocorticoid receptors. J. Steroid Biochem. 17, 335-342 (1982).
    • (1982) J. Steroid Biochem. , vol.17 , pp. 335-342
    • Manz, B.1    Grill, H.-J.2    Follow, K.3
  • 20
    • 0029824170 scopus 로고    scopus 로고
    • A three-hybrid system for detecting small ligand-protein receptor interactions
    • Licitra, E.J. & Liu, J.O. A three-hybrid system for detecting small ligand-protein receptor interactions. Proc. Natl. Acad. Sci. USA 93, 12817-12821 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12817-12821
    • Licitra, E.J.1    Liu, J.O.2
  • 22
    • 0027934780 scopus 로고
    • Discovery of nanomolar ligands for 7-transmerrjbrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library
    • Zuckermann, R.N. et al. Discovery of nanomolar ligands for 7-transmerrjbrane G-protein-coupled receptors from a diverse N-(substituted)glycine peptoid library. J. Med. Chem. 37, 2678-2685 (1994).
    • (1994) J. Med. Chem. , vol.37 , pp. 2678-2685
    • Zuckermann, R.N.1
  • 23
    • 0036606916 scopus 로고    scopus 로고
    • Development of protein-detecting microarrays and related devices
    • Kodadek, T. Development of protein-detecting microarrays and related devices. Trends Biochem. Sci. 27, 295-300 (2002).
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 295-300
    • Kodadek, T.1
  • 24
    • 0037596751 scopus 로고    scopus 로고
    • Synthetic small molecules that control stem cell fate
    • Ding, S. et al. Synthetic small molecules that control stem cell fate. Proc. Natl. Acad. Sci. USA 100, 7632-7637 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7632-7637
    • Ding, S.1
  • 25
    • 0033615357 scopus 로고    scopus 로고
    • Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
    • Mayer, T.U. et al. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science 286, 971-974 (1999).
    • (1999) Science , vol.286 , pp. 971-974
    • Mayer, T.U.1
  • 26
    • 0347717672 scopus 로고    scopus 로고
    • Dedifferentiation of lineage-committed cells by a small molecule
    • Chen, S., Zhang, Q., Wu, X., Schultz, P.G. & Ding, S. Dedifferentiation of lineage-committed cells by a small molecule. J. Am. Chem. Soc. 126, 410-411 (2004).
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 410-411
    • Chen, S.1    Zhang, Q.2    Wu, X.3    Schultz, P.G.4    Ding, S.5
  • 27
    • 0034700166 scopus 로고    scopus 로고
    • Small molecule developmental screens reveal the logic and timing of vertebrate development
    • Peterson, R.T., Link, B.A., Dowling, J.E. & Schreiber, S.L. Small molecule developmental screens reveal the logic and timing of vertebrate development. Proc. Natl. Acad. Sci. USA 97, 12965-12969 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12965-12969
    • Peterson, R.T.1    Link, B.A.2    Dowling, J.E.3    Schreiber, S.L.4
  • 28
    • 0030458462 scopus 로고    scopus 로고
    • How structural features influence the biomembrane permeability of peptides
    • Burton, P.S., Conradi, R.A., Ho, N.F.H., Hilgers, A.R. & Borchard, R.T. How structural features influence the biomembrane permeability of peptides. J. Pharm. Sci., 85, 1336-1340 (1996).
    • (1996) J. Pharm. Sci. , vol.85 , pp. 1336-1340
    • Burton, P.S.1    Conradi, R.A.2    Ho, N.F.H.3    Hilgers, A.R.4    Borchard, R.T.5
  • 29
    • 0033002003 scopus 로고    scopus 로고
    • Strategies toward predicting peptide cellular permeability from computed molecular descriptors
    • Goodwin, J.T., Mao, B., Vidmar, T.J., Conradi, R.A. & Burton, P.S. Strategies toward predicting peptide cellular permeability from computed molecular descriptors. J. Pept. Res. 53, 355-369 (1999).
    • (1999) J. Pept. Res. , vol.53 , pp. 355-369
    • Goodwin, J.T.1    Mao, B.2    Vidmar, T.J.3    Conradi, R.A.4    Burton, P.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.