Intestinal absorption screening of mixtures from combinatorial libraries in the Caco-2 model

Pharmaceutical Research

Volumn 14, Issue 5, 1997, Pages 572-577

  Taylor, Eric W ^a   Gibbons, Jacqueline A ^a   Braeckman, Rene A ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Caco 2; Combinatorial chemistry; Intestinal absorption; Mixtures; Structure activity relationships (SAR); Structure transport relationships

Indexed keywords

PEPTIDE DERIVATIVE;

ARTICLE; CELL STRAIN CACO 2; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG MIXTURE; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; PRIORITY JOURNAL; SCREENING; STRUCTURE ACTIVITY RELATION;

BIOLOGICAL TRANSPORT, ACTIVE; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CHEMISTRY, PHYSICAL; DRUG DELIVERY SYSTEMS; DRUG EVALUATION, PRECLINICAL; GLYCINE; HUMANS; INTESTINAL ABSORPTION; MASS SPECTROMETRY; PEPTIDES; PEPTOIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031005057     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012140709158     Document Type: Article

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