-
1
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet, P., D. Metcalf, D. C. S. Huang, D. M. Tarlinton, T. W. H. Kay, F. Königen, J. M. Adams, and A. Strasser. 1999. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286: 1735-1738.
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.S.3
Tarlinton, D.M.4
Kay, T.W.H.5
Königen, F.6
Adams, J.M.7
Strasser, A.8
-
2
-
-
0034508217
-
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
-
Lindsten, T., A. J. Ross, A. King, W. X. Zong, J. C. Rathmell, H. A. Shiels, E. Ulrich, K. G. Waymire, P. Mahar, K. Frauwirth, et al. 2000. The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol. Cell 6: 1389-1399.
-
(2000)
Mol. Cell
, vol.6
, pp. 1389-1399
-
-
Lindsten, T.1
Ross, A.J.2
King, A.3
Zong, W.X.4
Rathmell, J.C.5
Shiels, H.A.6
Ulrich, E.7
Waymire, K.G.8
Mahar, P.9
Frauwirth, K.10
-
3
-
-
0034641898
-
CD95's deadly mission in the immune system
-
Krammer, P. H. 2000. CD95's deadly mission in the immune system. Nature 407: 789-795.
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
4
-
-
0034574306
-
The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity
-
Siegel, R. M., F. K. Chan, H. I. Chun, and M. J. Lenardo. 2000. The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity. Nat. Immunol. 1: 469-474.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 469-474
-
-
Siegel, R.M.1
Chan, F.K.2
Chun, H.I.3
Lenardo, M.J.4
-
5
-
-
0029006893
-
Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
-
Rieux-Laucat, F., F. Le Deist, C. Hivroz, I. A. G. Roberts, K. M. Debatin, A. Fischer, and J. P. de Villartay. 1995. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268: 1347-1349.
-
(1995)
Science
, vol.268
, pp. 1347-1349
-
-
Rieux-Laucat, F.1
Le Deist, F.2
Hivroz, C.3
Roberts, I.A.G.4
Debatin, K.M.5
Fischer, A.6
De Villartay, J.P.7
-
6
-
-
0029025441
-
Dominant interfering Fas gene mutations
-
Fisher, G. H., F. J. Rosenberg, S. E. Straus, J. K. Dale, L. A. Middelton, A. Y. Lin, W. Strober, M. J. Lenardo, and J. M. Puck. 1995. Dominant interfering Fas gene mutations. Cell 81: 935-946.
-
(1995)
Cell
, vol.81
, pp. 935-946
-
-
Fisher, G.H.1
Rosenberg, F.J.2
Straus, S.E.3
Dale, J.K.4
Middelton, L.A.5
Lin, A.Y.6
Strober, W.7
Lenardo, M.J.8
Puck, J.M.9
-
7
-
-
0033538475
-
Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II
-
Wang, J., L. Zheng, A. Lobito, F. K. Chan, J. Dale, M. Sneller, X. Yao, J. M. Puck, S. E. Straus, and M. J. Lenardo. 1999. Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. Cell 98: 47-58.
-
(1999)
Cell
, vol.98
, pp. 47-58
-
-
Wang, J.1
Zheng, L.2
Lobito, A.3
Chan, F.K.4
Dale, J.5
Sneller, M.6
Yao, X.7
Puck, J.M.8
Straus, S.E.9
Lenardo, M.J.10
-
8
-
-
18544383460
-
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
-
Chun, H. J., L. Zheng, M. Ahmad, J. Wang, C. K. Speirs, R. M. Siegel, J. K. Dale, J. Puck, J. Davis, C. G. Hall, et al. 2002. Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature 419: 395-399.
-
(2002)
Nature
, vol.419
, pp. 395-399
-
-
Chun, H.J.1
Zheng, L.2
Ahmad, M.3
Wang, J.4
Speirs, C.K.5
Siegel, R.M.6
Dale, J.K.7
Puck, J.8
Davis, J.9
Hall, C.G.10
-
9
-
-
0142259712
-
Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
-
Rudd, C. E., and H. Schneider. 2003. Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling. Nat. Rev. Immunol. 3: 544-556.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 544-556
-
-
Rudd, C.E.1
Schneider, H.2
-
10
-
-
0032881288
-
AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation
-
Chan, T. O., S. E. Rittenhouse, and P. N. Tsichlis. 1999. AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation. Annu. Rev. Biochem. 68: 965-1014.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 965-1014
-
-
Chan, T.O.1
Rittenhouse, S.E.2
Tsichlis, P.N.3
-
11
-
-
0035489468
-
PKB/AKT: Functional insights from genetic models
-
Scheid, M. P., and J. R. Woodgett. 2001. PKB/AKT: functional insights from genetic models. Nat. Rev. Mol. Cell Biol. 2: 760-768.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 760-768
-
-
Scheid, M.P.1
Woodgett, J.R.2
-
12
-
-
0034107671
-
Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo
-
Borlado, L. R., C. Redondo, B. Alverez, C. Jimenez, L. M. Criado, J. Flores, M. A. Marcos, C. Martinez-A, D. Balomenos, and A. C. Carrera. 2000. Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo. FASEB J. 14: 895-903.
-
(2000)
FASEB J.
, vol.14
, pp. 895-903
-
-
Borlado, L.R.1
Redondo, C.2
Alverez, B.3
Jimenez, C.4
Criado, L.M.5
Flores, J.6
Marcos, M.A.7
Martinez-A, C.8
Balomenos, D.9
Carrera, A.C.10
-
14
-
-
0034995242
-
T cell-specific loss of Pten leads to defects in central and peripheral tolerance
-
Suzuki, A., M. T. Yamaguchi, T. Ohteki, T. Sasaki, T. Kaisho, Y. Kimura. R. Yoshida, A. Wakeham, T. Higuchi, M. Fukumoto, et al. 2001. T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity 14: 523-534.
-
(2001)
Immunity
, vol.14
, pp. 523-534
-
-
Suzuki, A.1
Yamaguchi, M.T.2
Ohteki, T.3
Sasaki, T.4
Kaisho, T.5
Kimura, Y.6
Yoshida, R.7
Wakeham, A.8
Higuchi, T.9
Fukumoto, M.10
-
15
-
-
0035399612
-
Expression of active PKB in T cells perturbs both T and B cell homeostasis and promotes inflammation
-
Parsons, M. I., R. G. Jones, M. S. Tsao, B. Odermatt, P. S. Ohashi, and J. R. Woodgett. 2001. Expression of active PKB in T cells perturbs both T and B cell homeostasis and promotes inflammation. J. Immunol. 167: 42-48.
-
(2001)
J. Immunol.
, vol.167
, pp. 42-48
-
-
Parsons, M.I.1
Jones, R.G.2
Tsao, M.S.3
Odermatt, B.4
Ohashi, P.S.5
Woodgett, J.R.6
-
16
-
-
0041975825
-
Activated Akt promotes increased resting T cell size CD28-independent T cell growth, and development of autoimmunity and lymphoma
-
Rathmell, J. C., R. L. Elstrom, R. M. Cinalli, and C. B. Thompson. 2003. Activated Akt promotes increased resting T cell size CD28-independent T cell growth, and development of autoimmunity and lymphoma. Eur. J. Immunol. 33: 2223-2232.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 2223-2232
-
-
Rathmell, J.C.1
Elstrom, R.L.2
Cinalli, R.M.3
Thompson, C.B.4
-
17
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-κB activity
-
Karin, M., and Y. Ben Neriah. 2000. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu. Rev. Immunol. 18: 621-663.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben Neriah, Y.2
-
19
-
-
0036679733
-
It's all rel-ative: NF-κB and CD28 costimulation of T-cell activation
-
Kane, L. P., J. Lin, and A. Weiss. 2002. It's all rel-ative: NF-κB and CD28 costimulation of T-cell activation. Trends Immunol. 23: 413-420.
-
(2002)
Trends Immunol.
, vol.23
, pp. 413-420
-
-
Kane, L.P.1
Lin, J.2
Weiss, A.3
-
20
-
-
0029992609
-
Suppression of TNF-α-induced apoptosis by NF-κB
-
Van Antwerp, D. J., S. J. Martin, T. Kafri, D. R. Green, and I. M. Verma. 1996. Suppression of TNF-α-induced apoptosis by NF-κB. Science 274: 787-789.
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
21
-
-
0031739867
-
Rel blocks both anti-Fas- and TNFα-induced apoptosis and an intact Rel transactivation domain is essential for this effect
-
Zong, W., J. Bash, and C. Gélinas. 1998. Rel blocks both anti-Fas- and TNFα-induced apoptosis and an intact Rel transactivation domain is essential for this effect. Cell Death Differ. 5: 963-972.
-
(1998)
Cell Death Differ.
, vol.5
, pp. 963-972
-
-
Zong, W.1
Bash, J.2
Gélinas, C.3
-
22
-
-
0033560024
-
A critical role for the RelA subunit of nuclear factor κB in regulation of multiple immune-response genes and in Fas-induced cell death
-
Ouaaz, F., M. Li, and A. A. Beg. 1999. A critical role for the RelA subunit of nuclear factor κB in regulation of multiple immune-response genes and in Fas-induced cell death. J. Exp. Med. 189: 999-1004.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 999-1004
-
-
Ouaaz, F.1
Li, M.2
Beg, A.A.3
-
23
-
-
0032588794
-
NF-κB regulates Fas/APO-1/CD95- and TCR-mediated apoptosis of T lymphocytes
-
Dudley, E., F. Hornung, L. Zheng, D. Scherer, D. Ballard, and M. Lenardo. 1999. NF-κB regulates Fas/APO-1/CD95- and TCR-mediated apoptosis of T lymphocytes. Eur. J. Immunol. 29: 878-886.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 878-886
-
-
Dudley, E.1
Hornung, F.2
Zheng, L.3
Scherer, D.4
Ballard, D.5
Lenardo, M.6
-
24
-
-
0035871841
-
NF-κB RelA (p65) is essential for TNF-α-induced Fas expression but dispensable for both TCR-induced expression and activation-induced cell death
-
Zheng, Y., F. Ouaaz, P. Bruzzo, V. Singh, S. Gerondakis, and A. A. Beg. 2001. NF-κB RelA (p65) is essential for TNF-α-induced Fas expression but dispensable for both TCR-induced expression and activation-induced cell death. J. Immunol. 166: 4949-4957.
-
(2001)
J. Immunol.
, vol.166
, pp. 4949-4957
-
-
Zheng, Y.1
Ouaaz, F.2
Bruzzo, P.3
Singh, V.4
Gerondakis, S.5
Beg, A.A.6
-
25
-
-
0041912330
-
L
-
L. Cell Death Differ. 10: 1032-1044.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 1032-1044
-
-
Mora, A.L.1
Corn, R.A.2
Stanic, A.K.3
Goenka, S.4
Aronica, M.5
Stanley, S.6
Ballard, D.W.7
Joyce, S.8
Boothby, M.9
-
26
-
-
0030925372
-
Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-κB
-
Boothby, M. R., A. L. Mora, D. C. Scherer, J. A. Brockman, and D. W. Ballard. 1997. Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-κB. J. Exp. Med. 185: 1897-1907.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1897-1907
-
-
Boothby, M.R.1
Mora, A.L.2
Scherer, D.C.3
Brockman, J.A.4
Ballard, D.W.5
-
27
-
-
0028804551
-
Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses
-
Sha, W. C., H.-C. Liou, E. L. Tuomanen, and D. Baltimore. 1995. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell 80: 321-330.
-
(1995)
Cell
, vol.80
, pp. 321-330
-
-
Sha, W.C.1
Liou, H.-C.2
Tuomanen, E.L.3
Baltimore, D.4
-
28
-
-
0029150389
-
Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity and interleukin-2 expression
-
Kontgen, F., R. J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlinton, and S. Gerondakis. 1995. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity and interleukin-2 expression. Genes Dev. 9: 1965-1977.
-
(1995)
Genes Dev.
, vol.9
, pp. 1965-1977
-
-
Kontgen, F.1
Grumont, R.J.2
Strasser, A.3
Metcalf, D.4
Li, R.5
Tarlinton, D.6
Gerondakis, S.7
-
29
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer, K., T. Matsuyama, T. M. Kündig, A. Wakeham, K. Kishihara, A. Shahinian, K. Wiegmann, P. S. Ohashi, M. Krönke, and T. W. Mak. 1993. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73: 456-467.
-
(1993)
Cell
, vol.73
, pp. 456-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kündig, T.M.3
Wakeham, A.4
Kishihara, K.5
Shahinian, A.6
Wiegmann, K.7
Ohashi, P.S.8
Krönke, M.9
Mak, T.W.10
-
30
-
-
0037025948
-
CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly
-
Jones, R. G., A. R. Elford, M. J. Parsons, L. Wu, C. M. Krawczyk, W.-C. Yeh, R. Hakem, R. Rottapel, J. R. Woodgett, and P. S. Ohashi. 2002. CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. J. Exp. Med. 196: 335-348.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 335-348
-
-
Jones, R.G.1
Elford, A.R.2
Parsons, M.J.3
Wu, L.4
Krawczyk, C.M.5
Yeh, W.-C.6
Hakem, R.7
Rottapel, R.8
Woodgett, J.R.9
Ohashi, P.S.10
-
31
-
-
0030890933
-
Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
-
Ahmed, N. N., H. L. Grimes, A. Bellacosa, T. O. Chan, and P. N. Tsichlis. 1997. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl. Acad. Sci. USA 94: 3627-3632.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3627-3632
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
32
-
-
0030908525
-
Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase
-
Reif, K., B. M. T. Burgering, and D. A. Cantrell. 1997. Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase. J. Biol. Chem. 272: 14426-14433.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14426-14433
-
-
Reif, K.1
Burgering, B.M.T.2
Cantrell, D.A.3
-
33
-
-
0037080219
-
IL-2 and related cytokines can promote T cell survival by activating AKT
-
Kelly, E., A. Won, Y. Refaeli, and L. van Parijs. 2002. IL-2 and related cytokines can promote T cell survival by activating AKT. J. Immunol. 168: 597-603.
-
(2002)
J. Immunol.
, vol.168
, pp. 597-603
-
-
Kelly, E.1
Won, A.2
Refaeli, Y.3
Van Parijs, L.4
-
34
-
-
0036009115
-
NF-κB at the crossroads of life and death
-
Karin, M., and A. Lin. 2002. NF-κB at the crossroads of life and death. Nat. Immunol. 3: 221-227.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
35
-
-
0028929371
-
Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation
-
Brockman, J. A., D. C. Scherer, T. A. McKinsey, S. M. Hall, X. Qi, W. Y. Lee, and D. W. Ballard. 1995. Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation. Mol. Cell. Biol. 15: 2809-2818.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2809-2818
-
-
Brockman, J.A.1
Scherer, D.C.2
McKinsey, T.A.3
Hall, S.M.4
Qi, X.5
Lee, W.Y.6
Ballard, D.W.7
-
36
-
-
0026068601
-
+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B
-
+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature 349: 245-248.
-
(1991)
Nature
, vol.349
, pp. 245-248
-
-
Kawabe, Y.1
Ochi, A.2
-
37
-
-
17944394558
-
Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells
-
Bonfoco, E., P. M. Stuart, T. Brunner, T. Lin, T. S. Griffith, Y. Gao, H. Nakajima, P. A. Henkart, T. A. Ferguson. and D. R. Green. 1998. Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells. Immunity 9: 711-720.
-
(1998)
Immunity
, vol.9
, pp. 711-720
-
-
Bonfoco, E.1
Stuart, P.M.2
Brunner, T.3
Lin, T.4
Griffith, T.S.5
Gao, Y.6
Nakajima, H.7
Henkart, P.A.8
Ferguson, T.A.9
Green, D.R.10
-
38
-
-
0036781052
-
NF-κB regulation in the immune system
-
Li, Q., and I. M. Verma. 2002. NF-κB regulation in the immune system. Nat. Rev. Immunol. 2: 725-734.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
39
-
-
0344406188
-
+ T cells reveals an essential requirement for nuclear factor κB in regulating mature T cell survival and in vivo function
-
+ T cells reveals an essential requirement for nuclear factor κB in regulating mature T cell survival and in vivo function. J. Exp. Med. 197: 861-874.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 861-874
-
-
Zheng, Y.1
Vig, M.2
Lyons, J.3
Van Parijs, L.4
Beg, A.A.5
-
40
-
-
0035448879
-
Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene
-
Chen, W. S., P.-S. Xu, K. Gottlob, M.-L. Chen, K. Sokol, T. Shiyanova, I. Roninson, W. Weng, R. Suzuki, K. Tobe, et al. 2001. Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene. Genes Dev. 15: 2203-2208.
-
(2001)
Genes Dev.
, vol.15
, pp. 2203-2208
-
-
Chen, W.S.1
Xu, P.-S.2
Gottlob, K.3
Chen, M.-L.4
Sokol, K.5
Shiyanova, T.6
Roninson, I.7
Weng, W.8
Suzuki, R.9
Tobe, K.10
-
41
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth, K. A., J. L. Riley, M. H. Harris, R. V. Parry, J. C. Rathmell, D. R. Plas, R. L. Elstrom, C. H. June, and C. B. Thompson. 2002. The CD28 signaling pathway regulates glucose metabolism. Immunity 16: 769-777.
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.A.1
Riley, J.L.2
Harris, M.H.3
Parry, R.V.4
Rathmell, J.C.5
Plas, D.R.6
Elstrom, R.L.7
June, C.H.8
Thompson, C.B.9
-
42
-
-
1142263117
-
The costimulation-regulated duration of PKB activation controls T cell longevity
-
Song, J., S. Salek-Ardakani, P. R. Rogers, M. Cheng, L. van Parijs, and M. Croft. 2004. The costimulation-regulated duration of PKB activation controls T cell longevity. Nat. Immunol. 1-9.
-
(2004)
Nat. Immunol.
, pp. 1-9
-
-
Song, J.1
Salek-Ardakani, S.2
Rogers, P.R.3
Cheng, M.4
Van Parijs, L.5
Croft, M.6
-
43
-
-
0042847224
-
Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation
-
Na, S.-Y., A. Patra, Y. Scheuring, A. Marx, M. Tolaini, D. Kioussis, B. Hemmings, T. Hünig, and U. Bommhardt. 2003. Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation. J. Immunol. 171: 1285-1296.
-
(2003)
J. Immunol.
, vol.171
, pp. 1285-1296
-
-
Na, S.-Y.1
Patra, A.2
Scheuring, Y.3
Marx, A.4
Tolaini, M.5
Kioussis, D.6
Hemmings, B.7
Hünig, T.8
Bommhardt, U.9
-
44
-
-
17744386318
-
Bcl10 is a positive regulator of antigen receptor-induced activation of NF-κB and neural tube closure
-
Ruland, J., G. S. Duncan, A. Elia, I. d. B. Barrantes, L. Nguyen, D. G. Millar, D. Bouchard, A. Wakeham, P. S. Ohashi, and T. W. Mak. 2001. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-κB and neural tube closure. Cell 104: 33-42.
-
(2001)
Cell
, vol.104
, pp. 33-42
-
-
Ruland, J.1
Duncan, G.S.2
Elia, A.3
Barrantes, I.D.B.4
Nguyen, L.5
Millar, D.G.6
Bouchard, D.7
Wakeham, A.8
Ohashi, P.S.9
Mak, T.W.10
-
45
-
-
0037827638
-
Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis
-
Jun, J. E., L. E. Wilson, C. G. Vinuesa, S. Lesage, M. Blery, L. A. Miosge, M. C. Cook, E. M. Kucharska, H. Hara, J. M. Penninger, et al. 2003. Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis. Immunity 18: 751-762.
-
(2003)
Immunity
, vol.18
, pp. 751-762
-
-
Jun, J.E.1
Wilson, L.E.2
Vinuesa, C.G.3
Lesage, S.4
Blery, M.5
Miosge, L.A.6
Cook, M.C.7
Kucharska, E.M.8
Hara, H.9
Penninger, J.M.10
-
46
-
-
0037490078
-
The MAGUK family protein CARD11 is essential for lymphocyte activation
-
Hara, H., T. Wada, C. Bakal, I. Kozieradzki, S. Suzuki, N. Suzuki, M. Nghiem, E. K. Griffiths, C. Krawczyk, B. Bauer, et al. 2003. The MAGUK family protein CARD11 is essential for lymphocyte activation. Immunity 18: 763-775.
-
(2003)
Immunity
, vol.18
, pp. 763-775
-
-
Hara, H.1
Wada, T.2
Bakal, C.3
Kozieradzki, I.4
Suzuki, S.5
Suzuki, N.6
Nghiem, M.7
Griffiths, E.K.8
Krawczyk, C.9
Bauer, B.10
-
47
-
-
0345358541
-
Differential requirement for Malt1 in T and B cell antigen receptor signaling
-
Ruland, J., G. S. Duncan, A. Wakeham, and T. W. Mak. 2003. Differential requirement for Malt1 in T and B cell antigen receptor signaling. Immunity 19: 749-758.
-
(2003)
Immunity
, vol.19
, pp. 749-758
-
-
Ruland, J.1
Duncan, G.S.2
Wakeham, A.3
Mak, T.W.4
-
48
-
-
0345374583
-
Regulation of NF-κB-dependent lymphocyte activation and development by paracaspase
-
Ruefli-Brasse, A. A., D. M. French, and V. M. Dixit. 2003. Regulation of NF-κB-dependent lymphocyte activation and development by paracaspase. Science 302: 1581-1584.
-
(2003)
Science
, vol.302
, pp. 1581-1584
-
-
Ruefli-Brasse, A.A.1
French, D.M.2
Dixit, V.M.3
-
49
-
-
0036316344
-
Akt-dependent phosphorylation specifically regulates Cot induction of NF-κB-dependent transcription
-
Kane, L. P., M. N. Mollenauer, Z. Xu, C. W. Turck, and A. Weiss. 2002. Akt-dependent phosphorylation specifically regulates Cot induction of NF-κB-dependent transcription. Mol. Cell. Biol. 22: 5962-5974.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5962-5974
-
-
Kane, L.P.1
Mollenauer, M.N.2
Xu, Z.3
Turck, C.W.4
Weiss, A.5
-
50
-
-
0035943657
-
Complex formation and cooperation of protein kinase Cθ and Akt1/protein kinase Bα in the NF-κB transactivation cascade in Jurkat T cells
-
Bauer, B., N. Krumböck, F. Fresser, F. Hochholdinger, M. Spitaler, A. Simm, F. Überall, B. Schraven, and G. Baier. 2001. Complex formation and cooperation of protein kinase Cθ and Akt1/protein kinase Bα in the NF-κB transactivation cascade in Jurkat T cells. J. Biol. Chem. 276: 31627-31634.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31627-31634
-
-
Bauer, B.1
Krumböck, N.2
Fresser, F.3
Hochholdinger, F.4
Spitaler, M.5
Simm, A.6
Überall, F.7
Schraven, B.8
Baier, G.9
-
51
-
-
0037464468
-
AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling
-
Bauer, B., M. Jenny, F. Fresser, F. Überall, and G. Baier. 2003. AKT1/PKBα is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling. FEBS Lett. 541: 155-162.
-
(2003)
FEBS Lett.
, vol.541
, pp. 155-162
-
-
Bauer, B.1
Jenny, M.2
Fresser, F.3
Überall, F.4
Baier, G.5
-
52
-
-
0033038491
-
Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-κB p65/RelA subunit
-
Sizemore, N., S. Leung, and G. R. Stark. 1999. Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-κB p65/RelA subunit. Mol. Cell. Biol. 19: 4798-4805.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4798-4805
-
-
Sizemore, N.1
Leung, S.2
Stark, G.R.3
-
53
-
-
0033961280
-
Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB
-
Madrid, L. V., C. Y. Wang, D. C. Guttridge, A. J. Schottelius, A. S. Baldwin, Jr., and M. W. Mayo. 2000. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB. Mol. Cell. Biol. 20: 1626-1638.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1626-1638
-
-
Madrid, L.V.1
Wang, C.Y.2
Guttridge, D.C.3
Schottelius, A.J.4
Baldwin Jr., A.S.5
Mayo, M.W.6
-
54
-
-
0035379555
-
Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38
-
Madrid, L. V., M. W. Mayo, J. Y. Reuther, and A. S. Baldwin, Jr. 2001. Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38. J. Biol. Chem. 276: 18934-18940.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18934-18940
-
-
Madrid, L.V.1
Mayo, M.W.2
Reuther, J.Y.3
Baldwin Jr., A.S.4
-
55
-
-
0037192829
-
PTEN blocks tumor necrosis factor-induced NF-κB-dependent transcription by inhibiting the transactivation potential of the p65 subunit
-
Mayo, M. W., L. V. Madrid, S. D. Westerheide, D. R. Jones, X. J. Yuan, A. S. Baldwin, Jr., and Y. E. Whang. 2002. PTEN blocks tumor necrosis factor-induced NF-κB-dependent transcription by inhibiting the transactivation potential of the p65 subunit. J. Biol. Chem. 277: 11116-11125.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11116-11125
-
-
Mayo, M.W.1
Madrid, L.V.2
Westerheide, S.D.3
Jones, D.R.4
Yuan, X.J.5
Baldwin Jr., A.S.6
Whang, Y.E.7
-
56
-
-
0035816727
-
Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP)
-
Suhara, T., T. Mano, B. E. Oliveira, and K. Walsh. 2001. Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP). Circ. Res. 89: 13-19.
-
(2001)
Circ. Res.
, vol.89
, pp. 13-19
-
-
Suhara, T.1
Mano, T.2
Oliveira, B.E.3
Walsh, K.4
-
57
-
-
0035831556
-
Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells
-
Panka, D. J., T. Mano, T. Suhara, K. Walsh, and J. W. Mier. 2001. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells. J. Biol. Chem. 276: 6893-6896.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6893-6896
-
-
Panka, D.J.1
Mano, T.2
Suhara, T.3
Walsh, K.4
Mier, J.W.5
-
58
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler, M., M. Thome, M. Hahne, P. Schneider, K. Hofmann, V. Steiner, J.-L. Bodmer, M. Schroter, K. Burns, C. Mattmann, et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature 388: 190-195.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer, J.-L.7
Schroter, M.8
Burns, K.9
Mattmann, C.10
-
59
-
-
0034741071
-
Inhibition of NF-κB in T cells blocks lymphoproliferation and partially rescues autoimmune disease in gld/gld mice
-
Vallabhapurapu, S., R.-P. Ryseck, M. Malewicz, D. S. Weih, and F. Weih. 2001. Inhibition of NF-κB in T cells blocks lymphoproliferation and partially rescues autoimmune disease in gld/gld mice. Eur. J. Immunol. 31: 2612-2622.
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2612-2622
-
-
Vallabhapurapu, S.1
Ryseck, R.-P.2
Malewicz, M.3
Weih, D.S.4
Weih, F.5
-
60
-
-
1942454327
-
Human lupus T cells resist inactivation and escape death by upregulating COX-2
-
Xu, L., L. Zhang, Y. Yi, H.-K. Kang, and S. K. Datta. 2004. Human lupus T cells resist inactivation and escape death by upregulating COX-2. Nat. Med. 10: 411-415.
-
(2004)
Nat. Med.
, vol.10
, pp. 411-415
-
-
Xu, L.1
Zhang, L.2
Yi, Y.3
Kang, H.-K.4
Datta, S.K.5
-
61
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet, A., A. Bonni, M. J. Zigmond, M. Z. Lin, P. Juo, L. S. Hu, M. J. Anderson, K. C. Arden, J. Blenis, and M. E. Greenberg. 1999. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96: 857-868.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
62
-
-
4143129696
-
Regulation of NF-κB, Th activation, and autoinflammation by the Forkhead transcription factor Foxo3a
-
Lin, L., J. D. Hron, and S. L. Peng. 2004. Regulation of NF-κB, Th activation, and autoinflammation by the Forkhead transcription factor Foxo3a. Immunity 21: 203-213.
-
(2004)
Immunity
, vol.21
, pp. 203-213
-
-
Lin, L.1
Hron, J.D.2
Peng, S.L.3
|