Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor κB in regulating mature T cell survival and in vivo function

Journal of Experimental Medicine

Volumn 197, Issue 7, 2003, Pages 861-874

  Zheng, Ye ^a   Vig, Monika ^b   Lyons, Jesse ^a   Van Parijs, Luk ^b   Beg, Amer A ^a  

^a Columbia University ^*  (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cell death; NF KB; T cell receptor; T lymphocytes; Transcription factor

Indexed keywords

CD4 ANTIGEN; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P50; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR REL;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL FUNCTION; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; GENETIC TRANSDUCTION; IN VIVO STUDY; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; RETROVIRUS; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD28; CD4-POSITIVE T-LYMPHOCYTES; CELL CYCLE; CELL DEATH; CELL SURVIVAL; I-KAPPA B KINASE; MICE; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-REL; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 0344406188     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021610     Document Type: Article

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