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Volumn 86, Issue 3, 2000, Pages 255-263

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo. An apoptosis-independent model of dilated heart failure

Author keywords

Apoptosis; Calcineurin; Cardiac hypertrophy; Caspase 3; Phenylephrine

Indexed keywords

CALCINEURIN; CALCIUM; CALMODULIN; CASPASE 3; CYCLOSPORIN; DEOXYGLUCOSE; STAUROSPORINE;

EID: 0033982992     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.3.255     Document Type: Article
Times cited : (199)

References (51)
  • 1
    • 0029001622 scopus 로고
    • DNA fragmentation of human infarcted myocardial cells demonstrated by the nick end labeling method and DNA agarose gel electrophoresis
    • Itoh G, Tamura J, Suzuki M, Suzuki Y, Ikeda H, Koike M, Nomura M, Jie T, Ito K. DNA fragmentation of human infarcted myocardial cells demonstrated by the nick end labeling method and DNA agarose gel electrophoresis. Am J Pathol. 1995;146:1325-1331.
    • (1995) Am J Pathol , vol.146 , pp. 1325-1331
    • Itoh, G.1    Tamura, J.2    Suzuki, M.3    Suzuki, Y.4    Ikeda, H.5    Koike, M.6    Nomura, M.7    Jie, T.8    Ito, K.9
  • 5
    • 0343307138 scopus 로고    scopus 로고
    • Death by design: Programmed cell death in cardiovascular biology and disease
    • MacLellan WR, Schneider MD. Death by design: programmed cell death in cardiovascular biology and disease. Circ Res. 1997;81:137-144.
    • (1997) Circ Res , vol.81 , pp. 137-144
    • Maclellan, W.R.1    Schneider, M.D.2
  • 6
    • 0032526374 scopus 로고    scopus 로고
    • Apoptosis: Basic mechanisms and implications for cardiovascular disease
    • Haunstetter A, Izumo S. Apoptosis: basic mechanisms and implications for cardiovascular disease. Circ Res. 1998;82:1111-1129.
    • (1998) Circ Res , vol.82 , pp. 1111-1129
    • Haunstetter, A.1    Izumo, S.2
  • 10
    • 0001739436 scopus 로고    scopus 로고
    • Stretch-mediated release of angiotensin II induces myocytes apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell
    • Leri A, Claudio PP, Li Q, Wang X, Reiss K, Wang S, Malhotra A, Kajstura J, Anversa P. Stretch-mediated release of angiotensin II induces myocytes apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest. 1998;101:1326-1342.
    • (1998) J Clin Invest , vol.101 , pp. 1326-1342
    • Leri, A.1    Claudio, P.P.2    Li, Q.3    Wang, X.4    Reiss, K.5    Wang, S.6    Malhotra, A.7    Kajstura, J.8    Anversa, P.9
  • 11
    • 0032912721 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis
    • Leri A, Liu Y, Claudio PP, Kajstura J, Wang X, Wang S, Kang P, Malhotra A, Anversa P. Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis. Am J Pathol. 1999;154:567-580.
    • (1999) Am J Pathol , vol.154 , pp. 567-580
    • Leri, A.1    Liu, Y.2    Claudio, P.P.3    Kajstura, J.4    Wang, X.5    Wang, S.6    Kang, P.7    Malhotra, A.8    Anversa, P.9
  • 12
    • 0030954131 scopus 로고    scopus 로고
    • Atrial natriuretic peptide induces apoptosis in neonatal rat cardiac myocytes
    • Wu CF, Bishopric NH, Pratt RE. Atrial natriuretic peptide induces apoptosis in neonatal rat cardiac myocytes. J Biol Chem. 1997;272: 14860-14866.
    • (1997) J Biol Chem , vol.272 , pp. 14860-14866
    • Wu, C.F.1    Bishopric, N.H.2    Pratt, R.E.3
  • 14
    • 0032478822 scopus 로고    scopus 로고
    • MKK6 activates myocardial cell NF-κB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner
    • Zechner D, Craig R, Hanford DS, McDonough PM, Sabbadini RA, Glembotski CC. MKK6 activates myocardial cell NF-κB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner. J Biol Chem. 1998;273:8232-8239.
    • (1998) J Biol Chem , vol.273 , pp. 8232-8239
    • Zechner, D.1    Craig, R.2    Hanford, D.S.3    McDonough, P.M.4    Sabbadini, R.A.5    Glembotski, C.C.6
  • 15
    • 0031939753 scopus 로고    scopus 로고
    • Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
    • Wang Y, Huang S, Sah VP, Ross J Jr, Heller Brown J, Han J, Chien KR. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem. 1998;273:2161-2168.
    • (1998) J Biol Chem , vol.273 , pp. 2161-2168
    • Wang, Y.1    Huang, S.2    Sah, V.P.3    Ross J., Jr.4    Heller Brown, J.5    Han, J.6    Chien, K.R.7
  • 16
    • 0031041317 scopus 로고    scopus 로고
    • Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway: Divergence from downstream CT-1 signals for myocardial cell hypertrophy
    • Sheng Z, Knowlton K, Chen J, Hoshijima M, Brown JH, Chien KR. Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway: divergence from downstream CT-1 signals for myocardial cell hypertrophy. J Biol Chem. 1997;272:5783-5791.
    • (1997) J Biol Chem , vol.272 , pp. 5783-5791
    • Sheng, Z.1    Knowlton, K.2    Chen, J.3    Hoshijima, M.4    Brown, J.H.5    Chien, K.R.6
  • 17
    • 0030829808 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilatation, wall stress, and cardiac hypertrophy
    • Li Q, Li B, Wang X, Leri A, Jana KP, Liu Y, Kajstura J, Baserga R, Anversa P. Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilatation, wall stress, and cardiac hypertrophy. J Clin Invest. 1997;100: 1991-1999.
    • (1997) J Clin Invest , vol.100 , pp. 1991-1999
    • Li, Q.1    Li, B.2    Wang, X.3    Leri, A.4    Jana, K.P.5    Liu, Y.6    Kajstura, J.7    Baserga, R.8    Anversa, P.9
  • 18
    • 0031014651 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways
    • Parrizas M, Saltiel AR, LeRoith D. Insulin-like growth factor 1 inhibits apoptosis using the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. J Biol Chem. 1997;272:154-161.
    • (1997) J Biol Chem , vol.272 , pp. 154-161
    • Parrizas, M.1    Saltiel, A.R.2    Leroith, D.3
  • 19
    • 0032494175 scopus 로고    scopus 로고
    • Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor-1
    • Wang L, Ma W, Markovich R, Chen J-W, Wang PH. Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor-1. Circ Res. 1998;83:516-522.
    • (1998) Circ Res , vol.83 , pp. 516-522
    • Wang, L.1    Ma, W.2    Markovich, R.3    Chen, J.-W.4    Wang, P.H.5
  • 24
    • 0026455171 scopus 로고
    • Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism
    • Gomez-Foix AM, Coats WS, Baque S, Alam T, Gerard RD, Newgard CB. Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism. J Biol Chem. 1992;267:25129-25134.
    • (1992) J Biol Chem , vol.267 , pp. 25129-25134
    • Gomez-Foix, A.M.1    Coats, W.S.2    Baque, S.3    Alam, T.4    Gerard, R.D.5    Newgard, C.B.6
  • 25
    • 0032101282 scopus 로고    scopus 로고
    • Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes
    • Sun L, Youn HD., Loh C, Stolow M, He W, Liu JO. Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes. Immunity. 1998;8: 703-711.
    • (1998) Immunity , vol.8 , pp. 703-711
    • Sun, L.1    Youn, H.D.2    Loh, C.3    Stolow, M.4    He, W.5    Liu, J.O.6
  • 27
    • 0029836780 scopus 로고    scopus 로고
    • Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy
    • Mittereder N, March KL, Trapnell BC. Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J Virol. 1996;70: 7498-7509.
    • (1996) J Virol , vol.70 , pp. 7498-7509
    • Mittereder, N.1    March, K.L.2    Trapnell, B.C.3
  • 29
    • 0033617296 scopus 로고    scopus 로고
    • Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes
    • Malhotra R, Brosius FC III. Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes. J Biol Chem. 1999;274:12567-12575.
    • (1999) J Biol Chem , vol.274 , pp. 12567-12575
    • Malhotra, R.1    Brosius F.C. III2
  • 30
  • 33
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of bad through the protein kinase akt
    • del Peso L, Gonzalez-Garcia M, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science. 1997;278:687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Herrera, R.3    Nunez, G.4
  • 35
    • 0033517190 scopus 로고    scopus 로고
    • NF-kappaB is a target of AKT in anti-apoptotic PDGF signaling
    • Romashkova JA, Makarov SS. NF-kappaB is a target of AKT in anti-apoptotic PDGF signaling. Nature. 1999;401:86-90.
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 36
    • 0028001448 scopus 로고
    • Acute myocardial infarction leads to upregulation of the IGF-1 autocrine system, DNA replication, and nuclear mitotic division in the remaining viable cardiac myocytes
    • Reiss K, Kajstura J, Zhang X, Li P, Olivetti G, Anversa P. Acute myocardial infarction leads to upregulation of the IGF-1 autocrine system, DNA replication, and nuclear mitotic division in the remaining viable cardiac myocytes. Exp Cell Res. 1994;213:463-472.
    • (1994) Exp Cell Res , vol.213 , pp. 463-472
    • Reiss, K.1    Kajstura, J.2    Zhang, X.3    Li, P.4    Olivetti, G.5    Anversa, P.6
  • 37
    • 0032526374 scopus 로고    scopus 로고
    • Apoptosis: Basic mechanisms and implications for cardiovascular disease
    • Haunstetter A, Izumo S. Apoptosis: basic mechanisms and implications for cardiovascular disease. Circ Res. 1998;82:1111-1129.
    • (1998) Circ Res , vol.82 , pp. 1111-1129
    • Haunstetter, A.1    Izumo, S.2
  • 38
    • 0033593596 scopus 로고    scopus 로고
    • Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bax, and Bcl-x
    • Ing DJ, Dzau VJ, Webster KA, Bishopric NB. Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bax, and Bcl-x. Circ Res. 1999;84:21-33.
    • (1999) Circ Res , vol.84 , pp. 21-33
    • Ing, D.J.1    Dzau, V.J.2    Webster, K.A.3    Bishopric, N.B.4
  • 42
    • 0033565557 scopus 로고    scopus 로고
    • The mitochondrial permeability pore and its role in cell death
    • Crompton M. The mitochondrial permeability pore and its role in cell death. Biochem J. 1999;341:233-249.
    • (1999) Biochem J , vol.341 , pp. 233-249
    • Crompton, M.1
  • 43
    • 0032742696 scopus 로고    scopus 로고
    • Suppression or induction of apoptosis by opposing pathways downstream from calcium-activated calcineurin
    • Lotem J, Kama R, Sachs L. Suppression or induction of apoptosis by opposing pathways downstream from calcium-activated calcineurin. Proc Natl Acad Sci U S A. 1999;96:12016-12020.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12016-12020
    • Lotem, J.1    Kama, R.2    Sachs, L.3
  • 44
    • 0032561324 scopus 로고    scopus 로고
    • Induction of thymocyte apoptosis by Ca2+-independent protein kinase C (nPKC) activation and its regulation by calcineurin activation
    • Asada A, Zhao Y, Kondo S, Iwata M. Induction of thymocyte apoptosis by Ca2+-independent protein kinase C (nPKC) activation and its regulation by calcineurin activation. J Biol Chem. 1998;273:28392-28398.
    • (1998) J Biol Chem , vol.273 , pp. 28392-28398
    • Asada, A.1    Zhao, Y.2    Kondo, S.3    Iwata, M.4
  • 45
    • 0032516085 scopus 로고    scopus 로고
    • Different mechanisms for suppression of apoptosis by cytokines and calcium mobilizing compounds
    • Lotem J, Sachs L. Different mechanisms for suppression of apoptosis by cytokines and calcium mobilizing compounds. Proc Natl Acad Sci U S A. 1998;95:4601-4606.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 4601-4606
    • Lotem, J.1    Sachs, L.2
  • 46
    • 0030929913 scopus 로고    scopus 로고
    • Select alterations in protein kinases and phosphatases during apoptosis of differentiated PC12 cells
    • Davis PK, Dudek SM, Johnson GV. Select alterations in protein kinases and phosphatases during apoptosis of differentiated PC12 cells. J Neurochem. 1997;68:2338-2347.
    • (1997) J Neurochem , vol.68 , pp. 2338-2347
    • Davis, P.K.1    Dudek, S.M.2    Johnson, G.V.3
  • 47
    • 0029061299 scopus 로고
    • Calcineurin activation protects T cells from glucocorticoid-induced apoptosis
    • Zhao Y, Tozawa Y, Iseki R, Mukai M, Iwata M. Calcineurin activation protects T cells from glucocorticoid-induced apoptosis. J Immunol. 1995; 154:6346-6354.
    • (1995) J Immunol , vol.154 , pp. 6346-6354
    • Zhao, Y.1    Tozawa, Y.2    Iseki, R.3    Mukai, M.4    Iwata, M.5
  • 48
    • 0028971035 scopus 로고
    • Calcineurin functions in Ca(2+)-activated cell death in mammalian cells
    • Shibasaki F, McKeon F. Calcineurin functions in Ca(2+)-activated cell death in mammalian cells. J Cell Biol. 1995;131:735-743.
    • (1995) J Cell Biol , vol.131 , pp. 735-743
    • Shibasaki, F.1    McKeon, F.2
  • 49
    • 0030574021 scopus 로고    scopus 로고
    • Calcineurin and mitochondrial function in glutamate-induced neuronal cell death
    • Ankarcrona M, Dypbukt JM, Orrenius S, Nicotera P. Calcineurin and mitochondrial function in glutamate-induced neuronal cell death. FEbS Lett. 1996;394:321-324.
    • (1996) FEBS Lett , vol.394 , pp. 321-324
    • Ankarcrona, M.1    Dypbukt, J.M.2    Orrenius, S.3    Nicotera, P.4
  • 50
    • 0344026230 scopus 로고    scopus 로고
    • Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively
    • Toth R, Szegezdi E, Molnar G, Lord JM, Fesus L, Szondy Z. Regulation of cell surface expression of Fas (CD95) ligand and susceptibility to Fas (CD95)-mediated apoptosis in activation-induced T cell death involves calcineurin and protein kinase C, respectively. Eur J Immunol. 1999;29: 383-393.
    • (1999) Eur J Immunol , vol.29 , pp. 383-393
    • Toth, R.1    Szegezdi, E.2    Molnar, G.3    Lord, J.M.4    Fesus, L.5    Szondy, Z.6
  • 51
    • 0031238838 scopus 로고    scopus 로고
    • Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma
    • Denecker G, Vandenabeele P, Grooten J, Penning LC, Declercq W, Beyaert R, Buurman WA, Fiers W. Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma. Cytokine. 1997; 9:631-638.
    • (1997) Cytokine , vol.9 , pp. 631-638
    • Denecker, G.1    Vandenabeele, P.2    Grooten, J.3    Penning, L.C.4    Declercq, W.5    Beyaert, R.6    Buurman, W.A.7    Fiers, W.8


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