Low- and high-level transgenic expression of β2-adrenergic receptors differentially affect cardiac hypertrophy and function in Gαq-overexpressing mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 11, 1999, Pages 6400-6405

  Dorn II, Gerald W ^a   Tepe, Nicole M ^a   Lorenz, John N ^a   Koch, Walter J ^b   Liggett, Stephen B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; GENE PRODUCT; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN G ALPHA Q; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HEART MUSCLE FIBROSIS; HEART VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; TRANSGENE;

ANIMALS; ATRIAL NATRIURETIC FACTOR; CARDIOMEGALY; CROSSES, GENETIC; ECHOCARDIOGRAPHY; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEINS; HEART; HETEROZYGOTE; HUMANS; MICE; MICE, TRANSGENIC; MYOCARDIUM; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; VENTRICULAR FUNCTION, LEFT;

ANIMALIA; RODENTIA;

EID: 0033033440     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.11.6400     Document Type: Article

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