Decoding protein-protein interactions through combinatorial chemistry: Sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains

Biochemistry

Volumn 44, Issue 45, 2005, Pages 14932-14947

  Sweeney, Michael C ^a   Wavreille, Anne Sophie ^a   Park, Junguk ^a   Butchar, Jonathan P ^a   Tridandapani, Susheela ^a   Pei, Dehua ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DATABASE SYSTEMS; ENZYMES; MASS SPECTROMETRY;

COMBINATORIAL LIBRARY METHOD; HIGH-AFFINITY PEPTIDE LIGANDS; PROTEIN DOMAINS;

PROTEINS;

BINDING PROTEIN; INOSITOL PHOSPHATASE SHIP; LIGAND; PEPTIDE; PEPTIDE LIBRARY; PHOSPHATASE; PHOSPHOTYROSINE; PHOSPHOTYROSYL PEPTIDE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING COMPETITION; CARBOXY TERMINAL SEQUENCE; COMBINATORIAL CHEMISTRY; CONSENSUS SEQUENCE; DATA BASE; DEGRADATION; ITIM MOTIF; MASS SPECTROMETRY; PARTIAL EDMAN DEGRADATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SRC HOMOLOGY 2 DOMAIN; SRC HOMOLOGY DOMAIN; XP MOTIF; XPY MOTIF;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; DATABASES, PROTEIN; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MASS SPECTROMETRY; MICE; PEPTIDE LIBRARY; PEPTIDES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN INTERACTION MAPPING; PROTEIN-TYROSINE-PHOSPHATASE; SHP1 PROTEIN TYROSINE PHOSPHATASE; SRC HOMOLOGY DOMAINS;

EID: 24644500492     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051408h     Document Type: Article

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