-
1
-
-
0028146955
-
Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation
-
Arvidsson, A.-N., E. Rupp, E. Nanberg, J. Downward, L. Ronnstrand, S. Wennstrom, J. Schlessinger, C.-H. Heldin, and L. Claesson-Welsh. 1994. Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation. Mol. Cell. Biol. 14:6715-6726.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6715-6726
-
-
Arvidsson, A.-N.1
Rupp, E.2
Nanberg, E.3
Downward, J.4
Ronnstrand, L.5
Wennstrom, S.6
Schlessinger, J.7
Heldin, C.-H.8
Claesson-Welsh, L.9
-
2
-
-
0026689930
-
Cell death and control of cell survival in the oligodendrocyte lineage
-
Barres, B. A., I. K. Hart, H. S. Coles, R. Burne, J. F. Voyvodic, J. T. Richardson, and M. C. Raff. 1992. Cell death and control of cell survival in the oligodendrocyte lineage. Cell 70:31-46.
-
(1992)
Cell
, vol.70
, pp. 31-46
-
-
Barres, B.A.1
Hart, I.K.2
Coles, H.S.3
Burne, R.4
Voyvodic, J.F.5
Richardson, J.T.6
Raff, M.C.7
-
3
-
-
0028079681
-
The PDGF receptor alpha subunit activates p21ras and triggers DNA synthesis without interacting with ras-GAP
-
Bazenet, C., and A. Kazlauskas. 1994. The PDGF receptor alpha subunit activates p21ras and triggers DNA synthesis without interacting with ras-GAP. Oncogene 9:517-525.
-
(1994)
Oncogene
, vol.9
, pp. 517-525
-
-
Bazenet, C.1
Kazlauskas, A.2
-
4
-
-
0023722311
-
Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains
-
Beckmann, M. P., C. Betshollz, C.-H. Heldin, B. Westermark, E. DiMarco, P. P. Di Fiore, K. C. Robbins, and S. A. Aaronson. 1988. Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains. Science 241:1346-1349.
-
(1988)
Science
, vol.241
, pp. 1346-1349
-
-
Beckmann, M.P.1
Betshollz, C.2
Heldin, C.-H.3
Westermark, B.4
DiMarco, E.5
Di Fiore, P.P.6
Robbins, K.C.7
Aaronson, S.A.8
-
5
-
-
0026022620
-
Human microvascular endothelial cells express receptors for platelet-derived growth factor
-
Beitz, J. G., I.-S. Kim, P. Calabresi, and A. R. J. Frackelton. 1991. Human microvascular endothelial cells express receptors for platelet-derived growth factor. Proc. Natl. Acad. Sci. USA 88:2021-2025.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2021-2025
-
-
Beitz, J.G.1
Kim, I.-S.2
Calabresi, P.3
Frackelton, A.R.J.4
-
6
-
-
0030049783
-
Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression
-
Bennett, A. M., S. F. Hausdorff, A. M. O'Reilly, R. M. Freeman, and B. G. Neel. 1996. Multiple requirements for SHPTP2 in epidermal growth factor-mediated cell cycle progression. Mol. Cell. Biol. 16:1189-1202.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1189-1202
-
-
Bennett, A.M.1
Hausdorff, S.F.2
O'Reilly, A.M.3
Freeman, R.M.4
Neel, B.G.5
-
7
-
-
0028179013
-
Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras
-
Bennett, A. M., T. L. Tang, S. Sugimoto, C. T. Walsh, and B. J. Neel. 1994. Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras. Proc. Natl. Acad. Sci. USA 91:7335-7339.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7335-7339
-
-
Bennett, A.M.1
Tang, T.L.2
Sugimoto, S.3
Walsh, C.T.4
Neel, B.J.5
-
8
-
-
15844370315
-
PDGF-a signaling is a critical event in lung alveolar myofibroblast development and alveogenesis
-
Boström, H., K. Willetts, M. Pekny, P. Leveen, P. Lindahl, H. Hedstrand, M. Pekna, M. Hellström, S. Gebre-Medhin, M. Schalling, M. Nilsson, S. Kurland, J. Törnell, J. K. Heath, and C. Betsholtz. 1996. PDGF-a signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell 85:863-873.
-
(1996)
Cell
, vol.85
, pp. 863-873
-
-
Boström, H.1
Willetts, K.2
Pekny, M.3
Leveen, P.4
Lindahl, P.5
Hedstrand, H.6
Pekna, M.7
Hellström, M.8
Gebre-Medhin, S.9
Schalling, M.10
Nilsson, M.11
Kurland, S.12
Törnell, J.13
Heath, J.K.14
Betsholtz, C.15
-
9
-
-
0028589148
-
Platelet-derived growth factor receptor signals
-
Claesson-Welsh, L. 1994. Platelet-derived growth factor receptor signals. J. Biol. Chem. 269:32023-32026.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32023-32026
-
-
Claesson-Welsh, L.1
-
10
-
-
0028895654
-
Modular binding domains in signal transduction proteins
-
Cohen, G. B., R. Ren, and D. Baltimore. 1995. Modular binding domains in signal transduction proteins. Cell 80:237-248.
-
(1995)
Cell
, vol.80
, pp. 237-248
-
-
Cohen, G.B.1
Ren, R.2
Baltimore, D.3
-
12
-
-
0022081671
-
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation
-
Courtneidge, S. A. 1985. Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation. EMBO J. 4:1471-1477.
-
(1985)
EMBO J.
, vol.4
, pp. 1471-1477
-
-
Courtneidge, S.A.1
-
13
-
-
0026647411
-
Mouse platelet-derived growth factor α receptor: Sequence, tissue-specific expression and correlation with metastatic phenotype
-
Do, M.-S., C. Fitzer-Altas, J. Gubbaj, L. Greenfield, M. Feldman, and L. Eisenbach. 1992. Mouse platelet-derived growth factor α receptor: sequence, tissue-specific expression and correlation with metastatic phenotype. Oncogene 7:1567-1575.
-
(1992)
Oncogene
, vol.7
, pp. 1567-1575
-
-
Do, M.-S.1
Fitzer-Altas, C.2
Gubbaj, J.3
Greenfield, L.4
Feldman, M.5
Eisenbach, L.6
-
14
-
-
0027536088
-
Expression of platelet- derived growth factor (PDGF) and PDGF α- and β-receptors in the peripheral nervous system: An analysis of sciatic nerve and dorsal root ganglia
-
Eccleston, P. A., K. Funa, and C.-H. Heldin. 1993. Expression of platelet- derived growth factor (PDGF) and PDGF α- and β-receptors in the peripheral nervous system: an analysis of sciatic nerve and dorsal root ganglia. Dev. Biol. 155:459-470.
-
(1993)
Dev. Biol.
, vol.155
, pp. 459-470
-
-
Eccleston, P.A.1
Funa, K.2
Heldin, C.-H.3
-
15
-
-
0028951440
-
Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors
-
Eriksson, A., E. Nanberg, L. Ronnstrand, U. Engstrom, U. Hellman, E. Rupp, G. Carpenter, C. H. Heldin, and L. Claesson-Welsh. 1995. Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors. J. Biol. Chem. 270:7773-7781.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7773-7781
-
-
Eriksson, A.1
Nanberg, E.2
Ronnstrand, L.3
Engstrom, U.4
Hellman, U.5
Rupp, E.6
Carpenter, G.7
Heldin, C.H.8
Claesson-Welsh, L.9
-
16
-
-
0026583942
-
PDGF α- and β-receptors activate unique and common signal transduction pathways
-
Eriksson, A., A. Siegbahn, B. Westermark, C.-H. Heldin, and L. Claesson-Welsh. 1992. PDGF α- and β-receptors activate unique and common signal transduction pathways. EMBO J. 11:543-550.
-
(1992)
EMBO J.
, vol.11
, pp. 543-550
-
-
Eriksson, A.1
Siegbahn, A.2
Westermark, B.3
Heldin, C.-H.4
Claesson-Welsh, L.5
-
17
-
-
0026652899
-
Distinct phosphotyrosines on a growth factor receptor hind to specific molecules that mediate different signaling pathways
-
Fantl, W. J., J. A. Escobedo, G. A. Martin, C. T. Turck, M. del Rosario, F. McCormick, and L. T. Williams. 1992. Distinct phosphotyrosines on a growth factor receptor hind to specific molecules that mediate different signaling pathways. Cell 69:413-423.
-
(1992)
Cell
, vol.69
, pp. 413-423
-
-
Fantl, W.J.1
Escobedo, J.A.2
Martin, G.A.3
Turck, C.T.4
Del Rosario, M.5
McCormick, F.6
Williams, L.T.7
-
18
-
-
0027531637
-
SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases
-
Feng, G.-S., C.-C. Hui, and T. Pawson. 1993. SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. Science 259:1607-1611.
-
(1993)
Science
, vol.259
, pp. 1607-1611
-
-
Feng, G.-S.1
Hui, C.-C.2
Pawson, T.3
-
19
-
-
0027535962
-
Expression of functionally intact PDGF-α receptors in highly metastatic 3LL lewis lung carcinoma cells
-
Fitzer-Attas, C., M. Feldman, and L. Eisenbach. 1993. Expression of functionally intact PDGF-α receptors in highly metastatic 3LL lewis lung carcinoma cells. Int. J. Cancer 53:315-322.
-
(1993)
Int. J. Cancer
, vol.53
, pp. 315-322
-
-
Fitzer-Attas, C.1
Feldman, M.2
Eisenbach, L.3
-
21
-
-
0027175182
-
Differences in substrate specificities of α and β platelet-derived growth factor (PDGF) receptors
-
Heidaran, M. A., J. F. Beeler, J.-C. Yu, T. Ishibashi, W. J. LaRochelle, J. H. Pierce, and S. A. Aaronson. 1993. Differences in substrate specificities of α and β platelet-derived growth factor (PDGF) receptors. J. Biol. Chem. 268:9287-9295.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 9287-9295
-
-
Heidaran, M.A.1
Beeler, J.F.2
Yu, J.-C.3
Ishibashi, T.4
Larochelle, W.J.5
Pierce, J.H.6
Aaronson, S.A.7
-
22
-
-
0000579617
-
Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia
-
Heldin, C.-H., B. Westermark, and A. Wasteson. 1981. Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia. Proc. Natl. Acad. Sci. USA 78:3664-3668.
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 3664-3668
-
-
Heldin, C.-H.1
Westermark, B.2
Wasteson, A.3
-
23
-
-
0027365546
-
Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms
-
Henriksen, R., K. Funa, E. Wilander, T. Backstrom, M. Ridderheim, and K. Oberg. 1993. Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms. Cancer Res. 53:4550-4554.
-
(1993)
Cancer Res.
, vol.53
, pp. 4550-4554
-
-
Henriksen, R.1
Funa, K.2
Wilander, E.3
Backstrom, T.4
Ridderheim, M.5
Oberg, K.6
-
24
-
-
85088671971
-
Expression of PDGF, VEGF and their receptors in non-small cell lung tumor cell lines
-
in press
-
Holm, C., D. Gineitis, G. S. McConville, and A. Kazlauskas. Expression of PDGF, VEGF and their receptors in non-small cell lung tumor cell lines. Int. J. Oncol., in press.
-
Int. J. Oncol.
-
-
Holm, C.1
Gineitis, D.2
McConville, G.S.3
Kazlauskas, A.4
-
25
-
-
0028077899
-
Differences in signal transduction between platelet-derived growth factor (PDGF) alpha and beta receptors in vascular smooth muscle cells. PDGF-BB is a potent mitogen, but PDGF-AA promotes only protein synthesis without activation of DNA synthesis
-
Inui, H., Y. Kitami, M. Tani, T. Kondo, and T. Inagami. 1994. Differences in signal transduction between platelet-derived growth factor (PDGF) alpha and beta receptors in vascular smooth muscle cells. PDGF-BB is a potent mitogen, but PDGF-AA promotes only protein synthesis without activation of DNA synthesis. J. Biol. Chem. 269:30546-30552.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30546-30552
-
-
Inui, H.1
Kitami, Y.2
Tani, M.3
Kondo, T.4
Inagami, T.5
-
26
-
-
0026557517
-
Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo
-
Kashishian, A., A. Kazlauskas, and J. A. Cooper. 1992. Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo. EMBO J. 11:1373-1382.
-
(1992)
EMBO J.
, vol.11
, pp. 1373-1382
-
-
Kashishian, A.1
Kazlauskas, A.2
Cooper, J.A.3
-
27
-
-
0028084335
-
Receptor tyrosine kinases and their targets
-
Kazlauskas, A. 1994. Receptor tyrosine kinases and their targets. Curr. Opin. Genet. Dev. 4:5-14.
-
(1994)
Curr. Opin. Genet. Dev.
, vol.4
, pp. 5-14
-
-
Kazlauskas, A.1
-
28
-
-
0024434183
-
Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins
-
Kazlauskas, A., and J. A. Cooper. 1989. Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins. Cell 58:1121-1133.
-
(1989)
Cell
, vol.58
, pp. 1121-1133
-
-
Kazlauskas, A.1
Cooper, J.A.2
-
29
-
-
0025042770
-
Phosphorylation of the PDGF receptor β subunit creates a tight binding site for phosphatidylinositol 3 kinase
-
Kazlauskas, A., and J. A. Cooper. 1990. Phosphorylation of the PDGF receptor β subunit creates a tight binding site for phosphatidylinositol 3 kinase. EMBO J. 9:3279-3266.
-
(1990)
EMBO J.
, vol.9
, pp. 3279-13266
-
-
Kazlauskas, A.1
Cooper, J.A.2
-
30
-
-
0027179869
-
The 64-kDa protein that associates with the platelet-derived growth factor receptor β subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp
-
Kazlauskas, A., G.-S. Feng, T. Pawson, and M. Valius. 1993. The 64-kDa protein that associates with the platelet-derived growth factor receptor β subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp. Proc. Natl. Acad. Sci. USA 90:6939-6942.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6939-6942
-
-
Kazlauskas, A.1
Feng, G.-S.2
Pawson, T.3
Valius, M.4
-
31
-
-
0026664293
-
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor β subunit
-
Kazlauskas, A., A. Kashishian, J. A. Cooper, and M. Valius. 1992. GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor β subunit. Mol. Cell. Biol. 12:2534-2544.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2534-2544
-
-
Kazlauskas, A.1
Kashishian, A.2
Cooper, J.A.3
Valius, M.4
-
32
-
-
0029085194
-
Identification of a putative Syp substrate, the PDGF beta receptor
-
Klinghoffer, A. R., and A. Kazlauskas. 1995. Identification of a putative Syp substrate, the PDGF beta receptor. J. Biol. Chem. 270:22208-22217.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22208-22217
-
-
Klinghoffer, A.R.1
Kazlauskas, A.2
-
33
-
-
0027490590
-
Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2
-
Lechleider, R. J., R. M. J. Freeman, and B. G. Neel. 1993. Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2. J. Biol. Chem. 268:13434-13438.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 13434-13438
-
-
Lechleider, R.J.1
Freeman, R.M.J.2
Neel, B.G.3
-
34
-
-
0027987263
-
Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins
-
Li, N., J. Schlessinger, and B. Margolis. 1994. Autophosphorylation mutants of the EGF-receptor signal through auxiliary mechanisms involving SH2 domain proteins. Oncogene 9:3457-3465.
-
(1994)
Oncogene
, vol.9
, pp. 3457-3465
-
-
Li, N.1
Schlessinger, J.2
Margolis, B.3
-
35
-
-
0028123457
-
A new function for a phosphotyrosine phosphatase: Linking GRB2-Sos to a receptor tyrosine kinase
-
Li, W., R. Nishimura, A. Kashishian, A. G. Batzer, W. J. H. Kim, J. A. Cooper, and J. Schlessinger. 1994. A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase. Mol. Cell. Biol. 14:509-517.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 509-517
-
-
Li, W.1
Nishimura, R.2
Kashishian, A.3
Batzer, A.G.4
Kim, W.J.H.5
Cooper, J.A.6
Schlessinger, J.7
-
36
-
-
0028136280
-
Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin
-
Milarski, K. L., and A. R. Saltiel. 1994. Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin. J. Biol. Chem. 269:21239-21243.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21239-21243
-
-
Milarski, K.L.1
Saltiel, A.R.2
-
37
-
-
0026641249
-
Point mutant in the FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis
-
Mohammadi, M., C. A. Dionne, W. Li, N. Li, T. Spival, A. M. Honegger, M. Jaye, and J. Schlessinger. 1992. Point mutant in the FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature (London) 358:681-684.
-
(1992)
Nature (London)
, vol.358
, pp. 681-684
-
-
Mohammadi, M.1
Dionne, C.A.2
Li, W.3
Li, N.4
Spival, T.5
Honegger, A.M.6
Jaye, M.7
Schlessinger, J.8
-
38
-
-
0026663734
-
A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest-derived cells
-
Morrison-Graham, K., G. C. Schatteman, T. Bork, D. F. Bowen-Pope, and J. A. Weston. 1992. A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest-derived cells. Development 115:133-143.
-
(1992)
Development
, vol.115
, pp. 133-143
-
-
Morrison-Graham, K.1
Schatteman, G.C.2
Bork, T.3
Bowen-Pope, D.F.4
Weston, J.A.5
-
39
-
-
0023747564
-
Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-α and their receptors in human malignant glioma cell lines
-
Nister, M., T. A. Libermann, C. Betsholtz, M. Pettersson, L. Claesson-Welsh, C.-H. Heldin, J. Schlessinger, and B. Westermark. 1988. Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-α and their receptors in human malignant glioma cell lines. Cancer Res. 48:3910-3918.
-
(1988)
Cancer Res.
, vol.48
, pp. 3910-3918
-
-
Nister, M.1
Libermann, T.A.2
Betsholtz, C.3
Pettersson, M.4
Claesson-Welsh, L.5
Heldin, C.-H.6
Schlessinger, J.7
Westermark, B.8
-
40
-
-
0026045167
-
Differential expression ot platelet-derived growth factor receptors in human malignant glioma cell lines
-
Nister, M. L., L. Claesson-Welsh, A. Eriksson, C. H. Heldin, and B. Westermark. 1991. Differential expression ot platelet-derived growth factor receptors in human malignant glioma cell lines. J. Biol. Chem. 266:16755-16763.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 16755-16763
-
-
Nister, M.L.1
Claesson-Welsh, L.2
Eriksson, A.3
Heldin, C.H.4
Westermark, B.5
-
41
-
-
0024282573
-
PDGF promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor cell
-
Noble, M., K. Murray, P. Stroobant, M. D. Waterfield, and P. Riddle. 1988. PDGF promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor cell. Nature (London) 333:560-562.
-
(1988)
Nature (London)
, vol.333
, pp. 560-562
-
-
Noble, M.1
Murray, K.2
Stroobant, P.3
Waterfield, M.D.4
Riddle, P.5
-
42
-
-
0027103825
-
Expression of mouse PDGF-A and PDGF α-receptor genes during pre- and post-implantation development: Evidence for a developmental shift from an autocrine to a paracrine mode of action
-
Palmieri, S. L., J. Payne, C. D. Stiles, J. D. Biggers, and M. Mercola. 1992. Expression of mouse PDGF-A and PDGF α-receptor genes during pre- and post-implantation development: evidence for a developmental shift from an autocrine to a paracrine mode of action. Mech. Dev. 39:181-191.
-
(1992)
Mech. Dev.
, vol.39
, pp. 181-191
-
-
Palmieri, S.L.1
Payne, J.2
Stiles, C.D.3
Biggers, J.D.4
Mercola, M.5
-
43
-
-
0028859279
-
Protein modules and signaling networks
-
Pawson, T. 1995. Protein modules and signaling networks. Nature (London) 373:573-578.
-
(1995)
Nature (London)
, vol.373
, pp. 573-578
-
-
Pawson, T.1
-
44
-
-
0026731562
-
2+ flux hut not mitogenesis
-
2+ flux hut not mitogenesis. Nature (London) 358:678-681.
-
(1992)
Nature (London)
, vol.358
, pp. 678-681
-
-
Peters, K.G.1
Marie, J.2
Wilson, E.3
Ives, H.E.4
Esconedo, J.5
Del Rosario, M.6
Mirda, D.7
Williams, L.T.8
-
45
-
-
0024282594
-
Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture
-
Raff, M. C., L. E. Lillien, W. D. Richardson, J. F. Burne, and M. D. Noble. 1988. Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature (London) 333:562-565.
-
(1988)
Nature (London)
, vol.333
, pp. 562-565
-
-
Raff, M.C.1
Lillien, L.E.2
Richardson, W.D.3
Burne, J.F.4
Noble, M.D.5
-
46
-
-
0023947394
-
A role for platelet-derived growth factor in normal gliogenesis in the central nervous system
-
Richardson, W. D., N. Pringle, M. J. Mosley, B. Westermark, and M. Dubois-Dalcq. 1988. A role for platelet-derived growth factor in normal gliogenesis in the central nervous system. Cell 53:309-319.
-
(1988)
Cell
, vol.53
, pp. 309-319
-
-
Richardson, W.D.1
Pringle, N.2
Mosley, M.J.3
Westermark, B.4
Dubois-Dalcq, M.5
-
48
-
-
0026750569
-
Regulation and role of PDGF receptor α-subunit expression during embryogenesis
-
Schatteman, G. C., K. Morrison-Graham, A. van Kuppen, J. A. Weston, and D. F. Bowen-Pope. 1992. Regulation and role of PDGF receptor α-subunit expression during embryogenesis. Development 115:123-131.
-
(1992)
Development
, vol.115
, pp. 123-131
-
-
Schatteman, G.C.1
Morrison-Graham, K.2
Van Kuppen, A.3
Weston, J.A.4
Bowen-Pope, D.F.5
-
50
-
-
0027418984
-
PDGF-AB requires PDGF receptor α-subunits for high-affinity, but not for low-affinity, binding and signal transduction
-
Seifert, R. A., A. van Koppen, and D. F. Bowen-Pope. 1993. PDGF-AB requires PDGF receptor α-subunits for high-affinity, but not for low-affinity, binding and signal transduction. J. Biol. Chem. 268:4473-4480.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 4473-4480
-
-
Seifert, R.A.1
Van Koppen, A.2
Bowen-Pope, D.F.3
-
51
-
-
0027361809
-
Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells
-
Shamah, S. M., C. D. Stiles, and A. Guhu. 1993. Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells. Mol. Cell. Biol. 13:7203-7212.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7203-7212
-
-
Shamah, S.M.1
Stiles, C.D.2
Guhu, A.3
-
52
-
-
0025913156
-
Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF β-type receptors and respond to PDGF
-
Smits, A., M. Kato, B. Westermark, M. Nister, C.-H. Heldin, and K. Funa. 1991. Neurotrophic activity of platelet-derived growth factor (PDGF): rat neuronal cells possess functional PDGF β-type receptors and respond to PDGF. Proc. Natl. Acad. Sci. USA 88:8159-8163.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 8159-8163
-
-
Smits, A.1
Kato, M.2
Westermark, B.3
Nister, M.4
Heldin, C.-H.5
Funa, K.6
-
53
-
-
0028237504
-
Potent SHC tyrosine phosphorylation by epidermal growth factor at low receptor density or in the absence of receptor autophosphorylation sites
-
Soler, C., C. V. Alvarez, L. Beguinot, and G. Carpenter. 1994. Potent SHC tyrosine phosphorylation by epidermal growth factor at low receptor density or in the absence of receptor autophosphorylation sites. Oncogene 9:2207-2215.
-
(1994)
Oncogene
, vol.9
, pp. 2207-2215
-
-
Soler, C.1
Alvarez, C.V.2
Beguinot, L.3
Carpenter, G.4
-
54
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
Songyang, Z., S. E. Shoelson, M. Chaudhuri, G. Gish, T. Pawson, W. G. Haser, F. King, T. Roberts, S. Ratnofsky, R. J. Lechleider, B. J. Neel, R. B. Birge, J. Fajardo, M. M. Chou, H. Hanafusa, B. Schaffhausen, and L. C. Cantley. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell 72:767-778.
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
Shoelson, S.E.2
Chaudhuri, M.3
Gish, G.4
Pawson, T.5
Haser, W.G.6
King, F.7
Roberts, T.8
Ratnofsky, S.9
Lechleider, R.J.10
Neel, B.J.11
Birge, R.B.12
Fajardo, J.13
Chou, M.M.14
Hanafusa, H.15
Schaffhausen, B.16
Cantley, L.C.17
-
55
-
-
0028351583
-
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps, fes, GRB-2, HCP, SHC, Syk, and Vav
-
Songyang, Z., S. E. Shoelson, J. McGlade, P. Olivier, T. Pawson, X. R. Bustelo, M. Barbacid, H. Sabe, H. Hanafusa, T. Yi, R. Ren, D. Baltimore, S. Ratnofsky, R. A. Feldman, and L. C. Cantley. 1994. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps, fes, GRB-2, HCP, SHC, Syk, and Vav. Mol. Cell. Biol. 14:2777-2785.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2777-2785
-
-
Songyang, Z.1
Shoelson, S.E.2
McGlade, J.3
Olivier, P.4
Pawson, T.5
Bustelo, X.R.6
Barbacid, M.7
Sabe, H.8
Hanafusa, H.9
Yi, T.10
Ren, R.11
Baltimore, D.12
Ratnofsky, S.13
Feldman, R.A.14
Cantley, L.C.15
-
56
-
-
0028059309
-
Abnormal kidney development and hematological disorders in PDGF β-receptor mutant mice
-
Soriano, P. 1994. Abnormal kidney development and hematological disorders in PDGF β-receptor mutant mice. Genes Dev. 8:1888-1896.
-
(1994)
Genes Dev.
, vol.8
, pp. 1888-1896
-
-
Soriano, P.1
-
57
-
-
0026020611
-
Platelet-derived growth factor receptor α-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation
-
Stephenson, D. A., M. Mercola, E. Anderson, C. Wang, C. D. Stiles, D. F. Bowen-Pope, and V. M. Chapman. 1991. Platelet-derived growth factor receptor α-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation. Proc. Natl. Acad. Sci. USA 88:6-10.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 6-10
-
-
Stephenson, D.A.1
Mercola, M.2
Anderson, E.3
Wang, C.4
Stiles, C.D.5
Bowen-Pope, D.F.6
Chapman, V.M.7
-
58
-
-
0026130677
-
1-Histidinol provides effective selection of retrovirus-vector-transduced keratinocytes without impairing their proliferative potential
-
Stockschlaeder, M. A., R. Storb, W. R. Osborne, and A. D. Miller. 1991. 1-Histidinol provides effective selection of retrovirus-vector-transduced keratinocytes without impairing their proliferative potential. Hum. Gene Ther. 2:33-39.
-
(1991)
Hum. Gene Ther.
, vol.2
, pp. 33-39
-
-
Stockschlaeder, M.A.1
Storb, R.2
Osborne, W.R.3
Miller, A.D.4
-
59
-
-
0028878979
-
The SH2-containing protein tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development
-
Tang, T. L., R. M. J. Freeman, A. M. O'Reilly, B. G. Neel, and S. Y. Sokol. 1995. The SH2-containing protein tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development. Cell 80: 473-483.
-
(1995)
Cell
, vol.80
, pp. 473-483
-
-
Tang, T.L.1
Freeman, R.M.J.2
O'Reilly, A.M.3
Neel, B.G.4
Sokol, S.Y.5
-
60
-
-
0027506762
-
Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor β subunit and are required for binding of phospholipase Cγ and a 64-kilodalton protein, respectively
-
Valius, M., C. Bazenet, and A. Kazlauskas. 1993. Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor β subunit and are required for binding of phospholipase Cγ and a 64-kilodalton protein, respectively. Mol. Cell. Biol. 13:133-143.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 133-143
-
-
Valius, M.1
Bazenet, C.2
Kazlauskas, A.3
-
61
-
-
0027211693
-
Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
-
Valius, M., and A. Kazlauskas. 1993. Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell 73:321-334.
-
(1993)
Cell
, vol.73
, pp. 321-334
-
-
Valius, M.1
Kazlauskas, A.2
-
62
-
-
0027159221
-
Reversion of autocrine transformation by a dominant negative platelet-derived growth factor mutant
-
Vassbotn, F. S., M. Andersson, B. Westermark, C.-H. Heldin, and A. Östman. 1993. Reversion of autocrine transformation by a dominant negative platelet-derived growth factor mutant. Mol. Cell. Biol. 13:4066-4076.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4066-4076
-
-
Vassbotn, F.S.1
Andersson, M.2
Westermark, B.3
Heldin, C.-H.4
Östman, A.5
-
63
-
-
0026753688
-
Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor signals in cells expressing both receptor types
-
Vassbotn, F. S., A. Ostman, S. Siegbahn, H. Holmsen, and C.-H. Heldin. 1992. Neomycin is a platelet-derived growth factor (PDGF) antagonist that allows discrimination of PDGF alpha- and beta-receptor signals in cells expressing both receptor types. J. Biol. Chem. 267:15635-15641.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 15635-15641
-
-
Vassbotn, F.S.1
Ostman, A.2
Siegbahn, S.3
Holmsen, H.4
Heldin, C.-H.5
-
64
-
-
0027399168
-
Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation
-
Vogel, W., R. Lammers, J. Huang, and A. Ulrich. 1993. Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation. Science 259:1611-1614.
-
(1993)
Science
, vol.259
, pp. 1611-1614
-
-
Vogel, W.1
Lammers, R.2
Huang, J.3
Ulrich, A.4
-
65
-
-
0027990829
-
Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction
-
Xiao, S., D. W. Rose, T. Sasaoka, H. Maegawa, T. R. Burke, Jr., P. P. Roller, S. E. Shoelson, and J. M. Olefsky. 1994. Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J. Biol. Chem. 269:21244-21248.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21244-21248
-
-
Xiao, S.1
Rose, D.W.2
Sasaoka, T.3
Maegawa, H.4
Burke Jr., T.R.5
Roller, P.P.6
Shoelson, S.E.7
Olefsky, J.M.8
-
66
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
-
Yamaguchi, K., K. Shirakabe, H. Shibuva, K. Irie, I. Oishi, N. Ueno, T. Taniguchi, E. Nishida, and K. Matsumoto. 1995. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 270:2008-2011.
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuva, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
Taniguchi, T.7
Nishida, E.8
Matsumoto, K.9
-
67
-
-
0026012736
-
PDGF A-chain gene is expressed by mammalian neurons during development and in maturity
-
Yen, H.-J., K. G. Ruit, Y.-X. Wang, W. C. Parks, W. D. Snider, and T. F. Deuel. 1991. PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell 64:209-216.
-
(1991)
Cell
, vol.64
, pp. 209-216
-
-
Yen, H.-J.1
Ruit, K.G.2
Wang, Y.-X.3
Parks, W.C.4
Snider, W.D.5
Deuel, T.F.6
-
68
-
-
0027512554
-
Developmental expression of the platelet-derived growth factor alpha-receptor gene in the mammalian central nervous system
-
Yen, H. J., I. Silos-Santiago, Y. X. Wang, R. J. George, W. D. Snider, and T. F. Deuel. 1993. Developmental expression of the platelet-derived growth factor alpha-receptor gene in the mammalian central nervous system. Proc. Natl. Acad. Sci. USA 90:1952-1956.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1952-1956
-
-
Yen, H.J.1
Silos-Santiago, I.2
Wang, Y.X.3
George, R.J.4
Snider, W.D.5
Deuel, T.F.6
-
69
-
-
0028043846
-
Biological function of PDGF-induced PI-3 kinases activity: Its role in alpha PDGF receptor-mediated mitogenic or chemotactic signaling
-
Yu, J.-C., J. S. Gutkind, D. Mahadevan, W. Li, K. A. Meyers, J. H. Pierce, and M. A. Heidaran. 1994. Biological function of PDGF-induced PI-3 kinases activity: its role in alpha PDGF receptor-mediated mitogenic or chemotactic signaling. J. Cell Biol. 127:479-487.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 479-487
-
-
Yu, J.-C.1
Gutkind, J.S.2
Mahadevan, D.3
Li, W.4
Meyers, K.A.5
Pierce, J.H.6
Heidaran, M.A.7
-
70
-
-
0025735518
-
Tyrosine mutations within the α platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction
-
Yu, J.-C., M. A. Heidaran, J. H. Pierce, J. S. Gutkind, D. Lombardi, M. Ruggiero, and S. A. Aaronson. 1991. Tyrosine mutations within the α platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction. Mol. Cell. Biol. 11:3780-3785.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 3780-3785
-
-
Yu, J.-C.1
Heidaran, M.A.2
Pierce, J.H.3
Gutkind, J.S.4
Lombardi, D.5
Ruggiero, M.6
Aaronson, S.A.7
-
71
-
-
0028930121
-
Differential requirement of a motif within the carboxyl-terminal domain of the alpha-platelet-derived growth factor (alphaPDGF) receptor for PDGF focus forming activity, chemotaxis or growth
-
Yu, J.-C., W. Li, L.-M. Wang, A. Uren, J. H. Pierce, and M. A. Heidaran. 1995. Differential requirement of a motif within the carboxyl-terminal domain of the alpha-platelet-derived growth factor (alphaPDGF) receptor for PDGF focus forming activity, chemotaxis or growth. J. Biol. Chem. 270: 7033-7036.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7033-7036
-
-
Yu, J.-C.1
Li, W.2
Wang, L.-M.3
Uren, A.4
Pierce, J.H.5
Heidaran, M.A.6
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