Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice

Experimental Gerontology

Volumn 40, Issue 8-9, 2005, Pages 685-693

  Anisimov, Vladimir N ^a,b   Berstein, Lev M ^a   Egormin, Peter A ^a   Piskunova, Tatiana S ^a   Popovich, Irina G ^a   Zabezhinski, Mark A ^a   Kovalenko, Irina G ^a   Poroshina, Tatiana E ^a   Semenchenko, Anna V ^a,b   Provinciali, Mauro ^c   Re, Francesca ^c   Franceschi, Claudio ^d  

^a N N PETROV RESEARCH INSTITUTE OF ONCOLOGY   (Russian Federation)

^b MAX PLANCK INSTITUTE FOR DEMOGRAPHIC RESEARCH   (Germany)

^c INRCA   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Biguanides; HER 2 neu; Mammary cancer; Transgenic mice

Indexed keywords

DRINKING WATER; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GLUCOSE; INSULIN; METFORMIN; SOMATOMEDIN C; TRIACYLGLYCEROL;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BREAST ADENOCARCINOMA; BREAST TUMOR; CALORIC RESTRICTION; CARCINOGENESIS; CONTROLLED STUDY; DEMOGRAPHY; ESTRUS CYCLE; FEMALE; FOOD INTAKE; GENE INACTIVATION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERINSULINEMIA; INTERNATIONAL NORMALIZED RATIO; LIFESPAN; LONGEVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION;

ADENOCARCINOMA; AGING; ANIMALS; BLOOD GLUCOSE; BODY TEMPERATURE; BODY WEIGHT; ESTRUS; FEMALE; GRANZYMES; HYPOGLYCEMIC AGENTS; INSULIN; LIPOPROTEINS, LDL; LONGEVITY; MAMMARY NEOPLASMS, ANIMAL; MEMBRANE GLYCOPROTEINS; METFORMIN; MICE; MICE, TRANSGENIC; PORE FORMING CYTOTOXIC PROTEINS; RECEPTOR, ERBB-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SERINE ENDOPEPTIDASES; THYROXINE; TRIGLYCERIDES; TRIIODOTHYRONINE;

DROSOPHILA MELANOGASTER; MAMMALIA; MUS MUSCULUS; NEMATODA;

EID: 24644475793     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2005.07.007     Document Type: Article

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