Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins

American Journal of Physiology - Renal Physiology

Volumn 276, Issue 5 45-5, 1999, Pages

  Tsukamoto, Tatsuo ^a   Nigam, Sanjay K ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

ATP depletion; Cytoskeleton; Occludin; Tyrosine phosphorylation; Zonula occludens 1

Indexed keywords

ADENOSINE TRIPHOSPHATE; GENISTEIN; OCCLUDIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVITY; ENZYME INHIBITION; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TIGHT JUNCTION;

EID: 0033004247     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1999.276.5.f737     Document Type: Article

References (56)

1. Anderson, J. M., M. S. Balda, and A. S. Fanning. The structure and regulation of tight junctions. Curr. Opin. Cell Biol. 5: 772-778, 1993.
2. Anderson, J. M., B. R. Stevenson, L. A. Jesaitis, D. A. Goodenough, and M. S. Mooseker. Characterization of ZO-1: a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells. J. Cell Biol. 106: 1141-1149, 1988.
3. Bacallao, R., A. Garfinkel, S. Monke, G. Zampighi, and L. J. Mandel. ATP depletion: a novel method to study junctional properties in epithelial tissues. I. Rearrangement of the actin cytoskeleton. J. Cell Sci. 107: 3301-3313, 1994.
4. Balda, M. S., L. Gonzalez-Mariscal, K. Matter, M. Cereijido, and J. M. Anderson. Assembly of the tight junction: the role of diacylglycerol. J. Cell Biol. 123: 293-302, 1993.
5. Beatch, M., L. A. Jesaitis, W. J. Gallin, D. Goodenough, and B. R. Stevenson. The tight junction protein ZO-2 contains three PDZ (PSD-95/Discs-large/ZO-1) domains and an alternatively spliced region. J. Biol. Chem. 271: 25723-25726, 1996.
6. Brady-Kalnay, S. M., T. Mourton, J. P. Nixon, G. E. Pietz, M. Kinch, H. Chen, R. Brackenbury, D. L. Rimm, R. L. D. Vecchio, and N. K. Tonks. Dynamic interaction of PTPm with multiple cadherins in vivo. J. Cell Biol. 141: 287-296, 1998.
7. Brown, D., and J. L. Stow. Protein trafficking and polarity in kidney epithelium: from cell biology to physiology. Physiol. Rev. 76: 245-297, 1996.
8. 1 cells. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F1038-F1045, 1991.
9. Cantley, L. G., E. J. G. Barros, M. Gandhi, M. Rauchman, and S. K. Nigam. Regulation of mitogenesis, motogenesis, and tubulogenesis by hepatocyte growth factor in renal collecting duct cells. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F271-F280, 1994.
10. Chertow, G. M. On the design and analysis of multicenter trials in acute renal failure. Am. J. Kidney Dis. 30: S96-S101, 1997.
11. Citi, S., and N. Denisenko. Phosphorylation of the tight junction cingulin and the effects of protein kinase inhibitors and activators in MDCK epithelial cells. J. Cell Sci. 108: 2917-2926, 1995.
12. Denker, B. M., and S. K. Nigam. Molecular structure and assembly of the tight junction. Am. J. Physiol. 274 (Renal Physiol. 43): F1-F9, 1998.
13. Denker, B. M., C. Saha, S. Khawaja, and S. K. Nigam. Involvement of a heterotrimeric G protein a subunit in tight junction biogenesis. J. Biol. Chem. 271: 25750-25753, 1996.
14. Doctor, R. B., R. Bacallao, and L. J. Mandel. Method for recovering ATP content and mitochondrial function after chemical anoxia in renal cell cultures. Am. J. Physiol. 266 (Cell Physiol. 35): C1803-C1811, 1994.
15. Dodane, V., and B. Kachar. Identification of isoforms of G proteins and PKC that colocalized tight junctions. J. Membr. Biol. 149: 199-209, 1996.
16. Edelstein, C. L., H. Ling, and R. W. Schrier. The nature of renal cell injury. Kidney Int. 51: 1341-1351, 1997.
17. Fanning, A. S., B. J. Jameson, L. A. Jesaitis, and J. M. Anderson. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J. Biol. Chem. 273: 29745-29753, 1998.
18. Finkel, T. Oxygen radicals and signaling. Curr. Opin. Cell Biol. 10: 248-253, 1998.
19. Fish, E. M., and B. A. Molitoris. Alterations in epithelial polarity and the pathogenesis of disease states. N. Engl. J. Med. 330: 1580-1588, 1994.
20. Franklin, S. C., M. Moulton, G. A. Sicard, M. R. Hammerman, and S. B. Miller. Insulin-like growth factor I preserves renal function postoperatively. Am. J. Physiol. 272 (Renal Physiol. 41): F257-F259, 1997.
21. Furuse, M., K. Fujita, T. Hiiragi, K. Fujimoto, and S. Tsukita. Claudin-1 and claudin-2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J. Cell Biol. 141: 1539-1550, 1998.
22. Furuse, M., M. Itoh, T. Hirase, A. Nagafuchi, S. Yonemura, S. Tsukita, and S. Tsukita. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J. Cell Biol. 127: 1617-1626, 1994.
23. Gumbiner, B. M. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84: 345-357, 1996.
24. Harris, R. C. Growth factor and cytokines in acute renal failure. Adv. Ren. Replace. Ther. 4: 43-53, 1997.
25. Haskins, J., L. Gu, E. S. Wittchen, J. Hibbard, and B. R. Stevenson. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interactions with ZO-1 and occludin. J. Cell Biol. 141: 199-208, 1998.
26. 2 and vanadate in vitro. Biochem. Biophys. Res. Commun. 188: 773-779, 1992.
27. Hirsberg, R. Biologically active peptides in acute renal failure: recent clinical trials. Nephrol. Dial. Transplant. 12: 1563-1566, 1997.
28. Itallie, C. M. V., M. S. Balda, and J. M. Anderson. Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells. J. Cell Sci. 108: 1735-1742, 1995.
29. Itoh, M., S. Yonemura, A. Nagafuchi, S. Tsukita, and S. Tsukita. A 220-kDa undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J. Cell Biol. 115: 1449-1462, 1991.
30. Johnson, K., and J. Weinberg. Postischemic renal injury due to oxygen radicals. Curr. Opin. Nephrol. Hypertens. 2: 625-635, 1993.
31. Keon, B. H., S. Schäfer, C. Kuhn, C. Grund, and W. W. Franke. Symplekin, a novel type of tight junction plaque protein. J. Cell Biol. 134: 1003-1018, 1996.
32. Kim, S. K. Tight junction, membrane-associated guanylate kinases and cell signaling. Curr. Opin. Cell Biol. 7: 641-649, 1995.
33. Kroshian, V. M., A. M. Sheridan, and W. Lieberthal. Functional and cytoskeletal changes induced by sublethal injury in proximal tubular epithelial cells. Am. J. Physiol. 266 (Renal Fluid Electrolyte Physiol. 35): F21-F30, 1994.
34. Kurihara, H., J. M. Anderson, and M. G. Farquhar. Increased Tyr phosphorylation of ZO-1 during modification of tight junctions between glomerular foot processes. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F514-F524, 1995.
35. Mandel, L. J., R. Bacallao, and G. Zampighi. Uncoupling of the molecular "fence" and paracellular "gate" functions in epithelial tight junctions. Nature 361: 552-555, 1993.
36. +-ATPase and E-cadherin. J. Cell Sci. 107: 3315-3324, 1994.
37. Mitic, L. L., and J. M. Anderson. Molecular architecture of tight junction. Annu. Rev. Physiol. 60: 121-142, 1998.
38. Molitoris, B. A., R. Dahl, and M. Hosford. Cellular ATP depletion induces disruption of the spectrin cytoskeletal network. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F790-F798, 1996.
39. Neel, B. G., and N. K. Tonks. Protein tyrosine phosphatases in signal transduction. Curr. Opin. Cell Biol. 9: 193-204, 1997.
40. Nigam, S. K., N. Denisenko, E. Rodriguez-Boulan, and S. Citi. The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells. Biochem. Biophys. Res. Commun. 181: 548-553, 1991.
41. Nusrat, A., M. Giry, J. R. Turner, S. P. Colgan, C. A. Parkos, D. Carnes, E. Lemichez, P. Boquet, and J. L. Madara. Rho protein regulates tight junction and perijunctional actin organization in polarized epithelia. Proc. Natl. Acad. Sci. USA 92: 10629-10633, 1995.
42. Saitou, M., K. Fujimoto, Y. Doi, M. Itoh, T. Fujimoto, M. Furuse, H. Takano, T. Noda, and S. Tsukita. Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J. Cell Biol. 141: 397-408, 1998.
43. Sakakibara, A., M. Furuse, M. Saitou, Y. Ando-Akatsuka, and S. Tsukita. Possible involvement of phosphorylation of occludin in tight junction formation. J. Cell Biol. 137: 1393-1401, 1997.
44. Staddon, J. M., K. Herrenknecht, C. Smales, and L. L. Rubin. Evidence that tyrosine phosphorylation may increase tight junction permeability. J. Cell Sci. 108: 609-619, 1995.
45. Stone, R. L., and J. E. Dixon. Protein-tyrosine phosphatases. J. Biol. Chem. 269: 31323-31326, 1994.
46. Stuart, R. O., and S. K. Nigam. Development of tubular nephron. Semin. Nephrol. 15: 315-326, 1995.
47. Stuart, R. O., and S. K. Nigam. Regulated assembly of tight junctions by protein kinase C. Proc. Natl. Acad. Sci. USA 92: 6072-6076, 1995.
48. Stuart, R. O., A. Sun, K. T. Bush, and S. K. Nigam. Dependence of epithelial intercellular junction biogenesis on thapsigargin-sensitive intracellular calcium stores. J. Biol. Chem. 271: 13636-13641, 1996.
49. Takeda, H., A. Nagafuchi, S. Yonemura, S. Tsukita, J. Behrens, W. Birchimeier, and S. Tsukita. V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and b catenin is not required for the shift. J. Cell Biol. 131: 1839-1847, 1995.
50. Takeda, H., and S. Tsukita. Effects of tyrosine phosphorylation on tight junction in temperature-sensitive v-src-transfected MDCK cells. Cell Struct. Funct. 20: 387-393, 1995.
51. Thadhani, R. M., M. Pascual, and J. V. Bonventre. Acute renal failure. N. Engl. J. Med. 334: 1448-1460, 1996.
52. Tsukamoto, T., and S. K. Nigam. Tight junction proteins form large complexes and associate with the cytoskeleton in an ATP depletion model for reversible junction assembly. J. Biol. Chem. 272: 16133-16139, 1997.
53. Weber, E., G. Berta, A. Tousson, P. S. John, M. W. Green, U. Gopalokrishnan, T. Jilling, E. J. Sorscher, T. S. Elton, D. R. Abrahamson, and K. L. Kirk. Expression and polarized targeting of a Rab3 isoform in epithelial cells. J. Cell Biol. 125: 583-594, 1994.
54. Wong, V. Phosphorylation of occludin correlates with occludin localization and function at the tight junction. Am. J. Physiol. 273 (Cell Physiol. 42): C1859-C1867, 1997.
55. Zahraoui, A., G. Joberty, M. Arpin, J. J. Fontaine, R. Hellio, A. Tavitian, and D. Louvard. A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells. J. Cell Biol. 124: 101-115, 1994.
56. Zhong, Y., K. Enomoto, H. Isomura, N. Sawada, T. Minase, M. Oyamada, Y. Konishi, and M. Mori. Localization of the 7H6 antigen at tight junctions correlates with the paracellular barrier function of MDCK cells. Exp. Cell Res. 214: 614-620, 1994.