The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells

Journal of Cell Biology

Volumn 139, Issue 3, 1997, Pages 785-795

  Yamamoto, Takaharu ^a   Harada, Naozumi ^a   Kano, Kyoko ^a   Taya, Shin Ichiro ^a   Canaani, Eli ^b   Matsuura, Yoshiharu ^c   Mizoguchi, Akira ^d   Ide, Chizuka ^d   Kaibuchi, Kozo ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL COMPOSITION; CELL PROLIFERATION; CELL TRANSFORMATION; ENZYME ACTIVATION; EPITHELIUM CELL; GENE REARRANGEMENT; GENE TARGETING; MONKEY; NONHUMAN; ONCOGENE C FOS; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TIGHT JUNCTION;

ALPHA CATENIN; ANIMALS; CALCIUM; CATTLE; CELL COMMUNICATION; CELL LINE; CYTOSKELETAL PROTEINS; DOGS; EPITHELIAL CELLS; FIBROBLASTS; INTESTINES; KIDNEY; KINESIN; MEMBRANE PROTEINS; MICE; MICROSCOPY, IMMUNOELECTRON; MYOSINS; PC12 CELLS; PHOSPHOPROTEINS; RAS PROTEINS; RATS; RECOMBINANT PROTEINS; TIGHT JUNCTIONS;

EID: 0030724368     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.139.3.785     Document Type: Article

References (52)

1. Anderson, J.M. 1996. Cell signaling: MAGUK magic. Curr. Biol 6:382-384.
2. Anderson, J.M., B.R. Stevenson, L.A. Jesaitis, D.A. Goodenough, and M.S. Mooseker. 1988. Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells. J. Cell Biol. 106:1141-1149.
3. Barbacid, M. 1987. Ras genes. Ann. Rev. Biochem. 56:779-827.
4. Basolo, F., J. Elliott, L. Tait, X.Q. Chen, T. Maloney, I.H. Russo, R. Pauley, S. Momiki, J. Caamano, A.J. Klein-Szanto, et al. 1991. Transformation of human breast epithelial cells by c-Ha-ras oncogene. Mol. Carcinog. 4:25-35.
5. Blenis, J. 1993. Signal transduction via the MAP kinases: proceed at your own RSK. Proc. Natl. Acad. Sci. USA. 90:5889-5892.
6. Bradford, M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
7. Brenman, J.E., D.S. Chao, S.H. Gee, A.W. McGee, S.E. Craven, D.R. Santillano, Z. Wu, F. Huang, H. Xia, M.F. Peters, et al. 1996. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and α1-syntrophin mediated by PDZ domains. Cell. 84:757-767.
8. Burry, R.W., D.D. Vandre, and D.M. Hayes. 1992. Silver enhancement of gold antibody probes in pre-embedding electron microscopic immunocytochemistry. J. Histochem. Cytochem. 40:1849-1856.
9. Cano, E., and L.C. Mahadevan. 1995. Parallel signal processing among mammalian MAPKs. Trends Biochem. Sci. 20:117-122.
10. Catling, A.D., C.W.M. Reuter, M.E. Cox, S.J. Parsons, and M.J. Weber. 1994. Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. J. Biol Chem. 269:30014-30021.
11. Cho, K.O., C.A. Hunt, and M.B. Kennedy. 1992. The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron. 9:929-942.
12. Daum, G., I. Eisenmann-Tappe, H.-W. Fries, J. Troppmair, and U.R. Rapp. 1994. The ins and outs of Raf kinases. Trends Biochem. Sci. 19:474-480.
13. Diamond, J. 1977. The epithelial junction: bridge, gate, and fence. Physiologist. 20:10-18.
14. Farquhar, M.G., and G.E. Palade. 1963. Junctional complexes in various epitheHa. J. Cell Biol. 17:375-412.
15. Furuse, M., M. Itoh, T. Hirase, A. Nagafuchi, S. Yonemura, Sa. Tsukita, and Sh. Tsukita. 1994. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J. Cell Biol. 127: 1617-1626.
16. Gumbiner, B.M. 1987. The structure, biochemistry and assembly of epithelial tight junctions. Am. J. Physiol. 253:C749-C758.
17. Gumbiner, B.M. 1996. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 84:345-357.
18. Gonzalez-Mariscal, L., B. Chavez de Ramirez, and M. Cereijido. 1985. Tight junction formation in cultured epithelial cells (MDCK). J. Membr. Biol. 86: 113-125.
19. Hall, A. 1994. Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu. Rev. Cell Biol. 10:31-54.
20. Han, L., and J. Colicelli. 1995. A human protein selected for interference with ras function interacts directly with ras and competes with raf1. Mol. Cell. Biol. 15:1318-1323.
21. Harlow, E., and D. Lane. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
22. Howarth, A.G., M.R. Hughes, and B.R. Stevenson. 1992. Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell types. Am. J. Physiol. 262:C461-C469.
23. Hülsken, J., J. Behrens, and W. Birchmeier. 1994. Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr. Opin. Cell Biol. 6:711-716.
24. Itoh, M., S. Yonemura, A. Nagafuchi, Sa. Tsukita, and Sh. Tsukita. 1991. A 220-kD undercoat-constitutive protein: its specific localization at cadherin-based cell-cell adhesion sites. J. Cell biol. 115:1449-1462.
25. Itoh, M., A. Nagafuchi, S. Yonemura, T. Kitani-Yasuda, Sa. Tsukita, and Sh. Tsukita. 1993. The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J. Cell. Biol. 121:491-502.
26. ras. Mol. Cell. Biol. 14:6944-6953.
27. Jongens, T.A., L.D. Ackerman, J.R. Swedlow, L.Y. Jan, and Y.N. Jan. 1994. Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila. Genes Dev. 8:2123-2136.
28. Kikuchi, A., S.D. Demo, Z.H. Ye, Y.W. Chen, and L.T. Williams. 1994. ralGDS family members interact with the effector loop of ras p21. Mol. Cell. Biol. 14: 7483-7491.
29. Kim, E., M. Niethammer, A. Rothschild, Y.N. Jan, and M. Sheng. 1995. Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases. Nature (Lond.). 378:85-88.
30. Kinch, M.S., G.J. Clark, C.J. Der, and K. Burridge. 1995. Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia. J. Cell Biol. 130:461-471.
31. Kornau, H.C., L.T. Schenker, M.B. Kennedy, and P.H. Seeburg. 1995. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science (Wash. DC). 269:1737-1740.
32. Kuriyama, M., N. Harada, S. Kuroda, T. Yamamoto, M. Nakafuku, A. Iwamatsu, D. Yamamoto, R. Prasad, C. Croce, E. Canaani, et al. 1996. Identification of AF-6 and canoe as putative targets for Ras. J. Biol. Chem. 271: 607-610.
33. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.). 227:680-685.
34. Marshall, C.J. 1995a. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell. 80: 179-185.
35. Marshall, M.S. 1995b. Ras target proteins in eukaryotic cells. FASEB J. 9:1311-1318.
36. Matsuo, T., K. Takahashi, S. Kondo, K. Kaibuchi, and D. Yamamoto. 1997. Regulation of cone cell formation by Canoe and Ras in the developing Drosophila eye. Development. 124:2671-2680.
37. Matsuura, Y., R.D. Possee, H.A. Overton, and D.H. Bishop. 1987. Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins. J. Gen. Virol. 68:1233-1250.
38. McCormick, F. 1994. Activators and effectors of ras p21 proteins. Curr. Opin. Genet. Dev. 4:71-76.
39. ras. GMPPNP is dependent on B-Raf. Mol. Cell. Biol. 14: 7153-7162.
40. Prasad, R., Y. Gu, H. Alder, T. Nakamura, O. Canaani, H. Saito, K. Huebner, R.P. Gale, P.C. Nowell, K. Kuriyama, et al. 1993. Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation. Cancer Res. 53:5624-5628.
41. Rajasekaran, A.K., M. Hojo, T. Huima, and E. Rodriguez-Boulan. 1996. Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions. J. Cell Biol. 132:451-463.
42. Rodriguez-Viciana, P., P.H. Warne, R. Dhand, B. Vanhaesebroeck, I. Gout, M.J. Fry, M.D. Waterfield, and J. Downward. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature (Lond.). 370:527-532.
43. Satoh, T., M. Nakafuku, and Y. Kaziro. 1992. Function of Ras as a molecular switch in signal transduction. J. Biol. Chem. 267:24149-24152.
44. Spaargaren, M., and J.R. Bischoff. 1994. Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap. Proc. Natl. Acad. Sci. USA. 91:12609-12613.
45. Sudol, M. 1996. The WW module competes with the SH3 domain? Trends Biochem. Sci. 21:161-163.
46. Takeichi, M, 1990. Cadherins: a molecular family important in selective cell-cell adhesion. Annu. Rev. Biochem. 59:237-252.
47. Tsukita, Sh., M. Itoh, A. Nagafuchi, S. Yonemura, and Sa. Tsukita. 1993. Submembranous junctional plaque proteins include potential tumor suppressor molecules. J. Cell Biol. 123:1049-1053.
48. Uchida, N., Y. Honjo, K.R. Johnson, M.J. Wheelock, and M. Takeichi. 1996. The catenin/cadherin adhesion system is localized in synaptic junction bordering transmitter release zones. J. Cell Biol. 135:767-779.
49. Vojtek, A.B., S.M. Hollenberg, and J.A. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell. 74:205-214.
50. Willott, E., M.S. Balda, A.S. Fanning, B. Jameson, C. Van Itallie, and J.M. Anderson. 1993. The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc. Natl. Acad. Sci. USA. 90:7834-7838.
51. Woods, D.F., and P.J. Bryant. 1991. The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions. Cell. 66:451-464.
52. Yamamori, B., S. Kuroda, K. Shimizu, K. Fukui, T. Ohtsuka, and Y. Takai. 1995. Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins. J. Biol. Chem. 270:11723-11726.