Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells

Molecular Biology of the Cell

Volumn 13, Issue 4, 2002, Pages 1227-1237

  Chen, Yan Hua ^a   Lu, Qun ^a   Goodenough, Daniel A ^a   Jeansonne, Beverly ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OCCLUDIN; PROTEIN INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE C YES; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL JUNCTION; CONTROLLED STUDY; DOG; ELECTRIC RESISTANCE; EPITHELIUM CELL; KIDNEY EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TIGHT JUNCTION;

ANIMALS; BLOTTING, WESTERN; CALCIUM; DOGS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-YES; PYRIMIDINES; PYRROLES; SRC-FAMILY KINASES; TIGHT JUNCTIONS; TIME FACTORS; TYROSINE;

ANIMALIA; CANIS FAMILIARIS;

EID: 0036226069     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.01-08-0423     Document Type: Article

References (64)

1. Genistein, a specific inhibitor of tyrosine-specific protein kinases
2. Interspecies diversity of the occludin sequence - cDNA cloning of human, mouse, dog, and rat-kangaroo homologues
3. Triton X-100-resistant membrane complexes from cultured kidney epithelial cells contain the Src family protein tyrosine kinase p62yes
4. Role of protein tyrosine phosphorylation in acetaldehyde-induced disruption of epithelial tight junctions
5. Assembly and sealing tight junctions: Possible participation of G-proteins, phospholipase C, protein kinase C and calmodulin
6. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein
7. Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene
8. The p60c-src family of protein-tyrosine kinases: Structure, regulation, and function
9. Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in Ras-transformed Madin-Darby Canine Kidney cells
10. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos
11. Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets
12. Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in M.D.C.K. epithelia
13. Xenopus laevis occludin. Identification of in vitro phosphorylation sites by protein kinase CK2 and association with cingulin
14. Involvement of a heterotrimeric G protein alpha subunit in tight junction biogenesis
15. Redistribution and phosphorylation of occludin during opening and resealing of tight junctions in cultured epithelial cells
16. Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling if intercellular junctional complexes
17. Occludin-a novel integral membrane protein localizing at tight junctions
18. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions
19. A third class of avian sarcoma viruses, defined by related transformation-specific proteins of Yamaguchi 73 and Esh sarcoma viruses
20. Independent regulation of adherens and tight junctions by tyrosine phosphorylation in Caco-2 cells
21. Plugging the leaks
22. Rho GTPase signaling regulates tight junction assembly and protects tight junctions during ATP depletion
23. Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1
24. Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein
25. Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases
26. Avian sarcoma virus Y73 genome sequence and structural similarity of its transforming gene product to that of Rous sarcoma virus
27. The role of Src kinase in the potentiation by ethanol of cytokine- and endotoxin-mediated nitric oxide synthase expression in rat hepatocytes
28. Increased tyr phosphorylation of ZO-1 during modification of tight junctions between glomerular foot processes
29. Small synthetic peptides homologous to segments of the first external loop of occludin impair tight junction resealing
30. Detection of sarcoma virus family tyrosine kinase activity in coronary arterial tissue
31. Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin
32. Transduction of basolateral-toapical signals across epithelial cells: Ligand-stimulated transcytosis of the polymeric immunoglobulin receptor requires two signals
33. The SRC family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo
34. Biogenesis of tight junctions - The C-terminal domain of occludin mediates basolateral targeting
35. Occludin is a functional component of the tight junction
36. Occludin localization at the tight junction requires the second extracellular loop
37. A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo
38. Connexin-occludin chimeras containing the ZO-binding domain of occludin localize at MDCK tight junctions and NRK cell contacts
39. Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50
40. Overexpression of protein kinase C-delta increases tight junction permeability in LLC-PK1 epithelia
41. Phospholipase C-γ 1 associates with viral and cellular src kinases
42. The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction
43. Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia
44. Involvement of Gα2 in the maintenance and biogenesis of epithelial cell tight junctions
45. Complex phenotype of mice lacking occludin, a component of tight junction strands
46. Possible involvement of phosphorylation of occludin in tight junction formation
47. Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells
48. Relationship of serine/threonine phosphorylation/dephosphorylation signaling to glucocorticoid regulation of tight junction permeability and zo-1 distribution in nontransformed mammary epithelial cells
49. Evidence that tyrosine phosphorylation may increase tight junction permeability
50. Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice
51. The tight junction: Morphology to molecules
52. Differential developmental expression of cellular yes and cellular src proteins in cerebellum
53. Cellular proteins homologous to the viral yes gene product
54. Monoclonal antibodies to the amino-terminal sequence of the c-yes gene product as specific probes of its expression
55. Characterization of cDNA clones for the human c-yes gene
56. The SH3 and SH2 domains are capable of directing specificity in protein interactions between the non-receptor tyrosine kinases cSrc and cYes
57. Active recombinant human tyrosine kinase c-Yes: Expression in baculovirus system, purification, comparison to c-Src, and inhibition by a c-Src inhibitor
58. Cellular functions regulated by Src family kinases
59. Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins
60. Structural and signaling molecules come together at tight junctions
61. Epidermal growth factor induces tyrosine phosphorylation and reorganization of the tight junction protein ZO-1 in A431 cells
62. Phosphorylation of occludin correlates with occludin localization and function at the tight junction
63. A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier
64. Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo