NZO-3 expression causes global changes to actin cytoskeleton in Madin-Darby canine kidney cells: Linking a tight junction protein to Rho GTPases

Molecular Biology of the Cell

Volumn 14, Issue 5, 2003, Pages 1757-1768

  Wittchen, Erika S ^a   Haskins, Julie ^a   Stevenson, Bruce R ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CATENIN; GUANOSINE TRIPHOSPHATASE; PROTEIN; PROTEIN ZO3; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL JUNCTION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; CYTOSKELETON; DOG; ENZYME ACTIVITY; FOCAL ADHESION; IMMUNOHISTOCHEMISTRY; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRESS FIBER; TIGHT JUNCTION; WOUND HEALING;

ACTINS; ANIMALS; CARRIER PROTEINS; CYTOSKELETON; DOGS; KIDNEY; MEMBRANE PROTEINS; RHO GTP-BINDING PROTEINS;

ANIMALIA; CANIS FAMILIARIS;

EID: 0038586530     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-08-0486     Document Type: Article

References (47)

1. Amano, M., Chihara, K., Kimura, K., Fukata, Y., Nakamura, N., Matsuura, Y., and Kaibuchi, K. (1997). Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science 275, 1308-1311.
2. Anastasiadis, P.Z., Moon, S.Y., Thoreson, M.A., Mariner, D.J., Crawford, H.C., Zheng, Y., and Reynolds, A.B. (2000). Inhibition of RhoA by p120 catenin. Nat. Cell Biol. 2, 637-644.
3. Balda, M.S., Gonzalez-Mariscal, L., Matter, K., Cereijido, M., and Anderson, J.M. (1993). Assembly of the tight junction: the role of diacylglycerol. J. Cell Biol. 123, 293-302.
4. Braga, V. (2000). The crossroads between cell-cell adhesion and motility. Nat. Cell Biol. 2, E182-E184.
5. Braga, VM., Machesky, L.M., Hall, A., and Hotchin, N.A. (1997). The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J. Cell Biol. 137, 1421-1431.
6. Bretscher, A., Reczek, D., and Berryman, M. (1997). Ezrin: a protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures. J. Cell Sci. 110, 3011-3018.
7. Bretscher, A., Chambers, D., Nguyen, R., and Reczek, D. (2000). ERM-Merlin and EBP50 protein families in plasma membrane organization and function. Annu. Rev. Cell Dev. Biol. 16, 113-143.
8. Chen, Y., Lu, Q., Schneeberger, E.E., and Goodenough, D.A. (2000). Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells. Mol. Biol. Cell 11, 849-862.
9. Grosheva, I, Shtutman, M., Elbaum, M., and Bershadsky, A.D. (2001). p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion. J. Cell Sci. 114, 695-707.
10. Gumbiner, B., Stevenson, B.R., and Grimaldi, A. (1988). The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J. Cell Biol. 107, 1575-1587.
11. Haskins, J., Gu, L., Wittchen, E.S., Hibbard, J., and Stevenson, B.R. (1998). ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J. Cell Biol. 141, 199-208.
12. Hecht, G., Pestic, L., Nikcevic, G., Koutsouris, A., Tripuraneni, J., Lorimer, D.D., Nowak, G., Guerriero, V., Jr., Elson, E.L., and Lanerolle, P.D. (1996). Expression of the catalytic domain of myosin light chain kinase increases paracellular permeability. Am. J. Physiol. 271, C1678-C1684.
13. Herman, I.M., Crisona, N.J., and Pollard, T.D. (1981). Relation between cell activity and the distribution of cytoplasmic actin and myosin. J. Cell Biol. 90, 84-91.
14. Itoh, M., Nagafuchi, A., Moroi, S., and Tsukita, S. (1997). Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J. Cell Biol. 138, 181-192.
15. Itoh, M., Morita, K., and Tsukita, S. (1999). Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha catenin. J. Biol. Chem. 274, 5981-5986.
16. Johnson, R.P., and Craig, S.W. (1994). An intramolecular association between the head and tail domains of vinculin modulates talin binding. J. Biol. Chem. 269, 12611-12619.
17. Johnson, R.P., and Craig, S.W. (1995). F-actin binding site masked by the intramolecular association of vinculin head and tail domains. Nature 373, 261-264.
18. Jou, T.S., Schneeberger, E.E., and Nelson, W.J. (1998). Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases. J. Cell Biol. 142, 101-115.
19. Kaibuchi, K., Kuroda, S., and Amano, M. (1999). Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu. Rev. Biochem. 68, 459-486.
20. Kuroda, S., Fukata, M., Fujii, K., Nakamura, T., Izawa, I., and Kaibuchi, K. (1997). Regulation of cell-cell adhesion of MDCK cells by Cdc42 and Rac1 small GTPases. Biochem. Biophys. Res. Commun. 240, 430-435.
21. Madara, J.L., and Pappenheimer, J.R. (1987). Structural basis for physiological regulation of paracellular pathways in intestinal epithelia. J. Membr. Biol. 100, 149-164.
22. Mercer, J.A. (2000). Intercellular junctions: downstream and upstream of Ras? Semin. Cell Dev. Biol. 11, 309-314.
23. Nakagawa, M., Fukata, M., Yamaga, M., Itoh, N., and Kaibuchi, K. (2001). Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell-cell adhesion sites. J. Cell Sci. 114, 1829-1838.
24. Nobes, C.D., and Hall, A. (1995). Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia, Cell 81, 53-62.
25. Nobes, C., and Hall, A. (1999). Rho GTPases control polarity, protrusion, and adhesion during cell movement. J. Cell Biol. 144, 1235-1244.
26. Noren, N.K., Liu, B.P., Burridge, K., and Kreft, B. (2000). p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J. Cell Biol. 150, 567-580.
27. Noren, N.K., Niessen, C.M., Gumbiner, B.M., and Burridge, K. (2001). Cadherin engagement regulates Rho family GTPases. J. Biol. Chem. 276, 33305-33308.
28. Nusrat, A., Giry, M., Turner, J.R., Colgan, S.P., Parkos, C.A., Carnes, D., Lemichez, E., Boquet, P., and Madara, J.L. (1995). Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. Proc. Natl. Acad. Sci. USA 92, 10629-10633.
29. Rajasekaran, A.K., Hojo, M., Huima, T., and Rodriguez-Boulan, E. (1996). Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions. J. Cell Biol. 132, 451-463.
30. Ren, R., Mayer, B.J., Cicchetti, P., and Baltimore, D. (1993). Identification of a ten-amino acid proline-rich SH3 binding site. Science 259, 1157-1161.
31. Ren, X.D., Kiosses, W.B., and Schwartz, M.A. (1999). Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J. 18, 578-585.
32. Ridley, A.J., Comoglio, P.M., and Hall, A. (1995). Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells. Mol. Cell. Biol. 15, 1110-1122.
33. Ridley, A.J., and Hall, A. (1992). The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.
34. Ridley, A.J., Paterson, H.F., Johnston, C.L., Diekmann, D., and Hall, A. (1992). The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410.
35. Sander, E.E., ten Klooster, J.P., van Delft, S., van der Kammen, R.A., and Collard, J.G. (1999). Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol. 147, 1009-1022.
36. Schoenenberger, C.A., Zuk, A., Kendall, D., and Matlin, K.S. (1991). Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras. J. Cell Biol. 112, 873-889.
37. Stevenson, B.R., and Begg, D.A. (1994). Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells. J. Cell Sci. 107, 367-375.
38. Takaishi, K., Sasaki, T., Kotani, H., Nishioka, H., and Takai, Y. (1997). Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J. Cell Biol. 139, 1047-1059.
39. Troxell, M.L., Gopalakrishnan, S., McCormack, J., Poteat, B.A., Pennington, J., Garringer, S.M., Schneeberger, E.E., Nelson, W.J., and Marrs, J.A. (2000). Inhibiting cadherin function by dominant mutant E-cadherin expression increases the extent of tight junction assembly. J. Cell Sci. 113, 985-996.
40. van Hengel, J., Vanhoenacker, P., Staes, K., and van Roy, F. (1999). Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression. Proc. Natl. Acad. Sci. USA 96, 7980-7985.
41. Walsh, S.V., Hopkins, A.M., Chen, J., Narumiya, S., Parkos, C.A., and Nusrat, A. (2001). Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia. Gastroenterology 121, 566-579.
42. Waterman-Storer, C.M., Worthylake, R.A., Liu, B.P., Burridge, K., and Salmon, E.D. (1999). Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts. Nat. Cell Biol. 1, 45-50.
43. Wittchen, E.S., Haskins, J., and Stevenson, B.R. (1999). Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3. J. Biol. Chem. 274, 35179-35185.
44. Wittchen, E.S., Haskins, J., and Stevenson, B.R. (2000). Exogenous expression of the amino terminal half of the tight junction protein ZO-3 perturbs junctional complex assembly. J. Cell Biol. 151, 825-836.
45. Wu, H., Reissner, C., Kuhlendahl, S., Coblentz, B., Reuver, S., Kindler, S., Gundelfinger, E.D., and Garner, C.C. (2000). Intramolecular interactions regulate SAP97 binding to GKAP. EMBO J. 19, 5740-5751.
46. Yamamoto, T., Harada, N., Kano, K., Taya, S.-I., Canaani, E., Matsuura, Y., Mizoguchi, A., Ide, C., and Kaibuchi, K. (1997). The ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. J. Cell Biol. 139, 785-795.
47. Yap, A.S., Niessen, C.M., and Gumbiner, B.M. (1998). The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. J. Cell Biol. 141, 779-789.