메뉴 건너뛰기




Volumn 276, Issue 3 39-3, 1999, Pages

Hepatocyte-specific localization and copper-dependent trafficking of the Wilson's disease protein in the liver

Author keywords

Adenosinetriphosphatase; Bile canaliculi; Ceruloplasmin; Golgi apparatus; Hepatolenticular degeneration

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CERULOPLASMIN; COPPER; PROTEIN;

EID: 0032920935     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.3.g639     Document Type: Article
Times cited : (212)

References (43)
  • 1
    • 0031024955 scopus 로고    scopus 로고
    • Presence of ATP-dependent copper transport in the hepatocyte canalicular membrane of the Long-Evans Cinnamon rat, an animal model of Wilson disease
    • Adachi, Y., Y. Okuyama, H. Miya, and T. Kamisako. Presence of ATP-dependent copper transport in the hepatocyte canalicular membrane of the Long-Evans Cinnamon rat, an animal model of Wilson disease. J. Hepatol. 26: 216, 1997.
    • (1997) J. Hepatol. , vol.26 , pp. 216
    • Adachi, Y.1    Okuyama, Y.2    Miya, H.3    Kamisako, T.4
  • 2
    • 0024462447 scopus 로고
    • A novel 58-kDa protein associates with the Golgi apparatus and microtubules
    • Bloom, G., and T. Brashear. A novel 58-kDa protein associates with the Golgi apparatus and microtubules. J. Biol. Chem. 264: 16083-16092, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 16083-16092
    • Bloom, G.1    Brashear, T.2
  • 3
    • 0028789248 scopus 로고
    • Vesicle targeting to the apical domain regulates bile excretory function in isolated rat hepatocyte couplets
    • Boyer, J. L., and C. L. Soroka. Vesicle targeting to the apical domain regulates bile excretory function in isolated rat hepatocyte couplets. Gastroenterology 109: 1600-1611, 1995.
    • (1995) Gastroenterology , vol.109 , pp. 1600-1611
    • Boyer, J.L.1    Soroka, C.L.2
  • 4
    • 0027452091 scopus 로고
    • The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene
    • Bull, P. C., G. R. Thomas, J. M. Rommers, J. R. Forbes, and D. W. Cox. The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene. Nat. Genet. 5: 327-337, 1993.
    • (1993) Nat. Genet. , vol.5 , pp. 327-337
    • Bull, P.C.1    Thomas, G.R.2    Rommers, J.M.3    Forbes, J.R.4    Cox, D.W.5
  • 5
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin, J. M., A. E. Pzybyla, R. J. MacDonald, and W. J. Rutter. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18: 5294-5299, 1979.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Pzybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 6
    • 0029799569 scopus 로고    scopus 로고
    • Molecular advances in Wilson disease
    • Cox, D. W. Molecular advances in Wilson disease. Prog. Liver Dis. 14: 245-264, 1996.
    • (1996) Prog. Liver Dis. , vol.14 , pp. 245-264
    • Cox, D.W.1
  • 7
    • 0029353191 scopus 로고
    • Wilson's disease: A new gene and an animal model for an old disease
    • Cuthbert, J. A. Wilson's disease: a new gene and an animal model for an old disease. J. Investig. Med. 43: 323-326, 1995.
    • (1995) J. Investig. Med. , vol.43 , pp. 323-326
    • Cuthbert, J.A.1
  • 8
    • 0031055871 scopus 로고    scopus 로고
    • Immunocytochemical localization of the Menkes copper transport protein (ATP7A) to the trans-Golgi network
    • Dierick, H. A., A. N. Adam, J. F. Escara-Wilke, and T. W. Glover. Immunocytochemical localization of the Menkes copper transport protein (ATP7A) to the trans-Golgi network. Hum. Mol. Genet. 6: 409-416, 1997.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 409-416
    • Dierick, H.A.1    Adam, A.N.2    Escara-Wilke, J.F.3    Glover, T.W.4
  • 10
    • 0028799373 scopus 로고
    • Chronic intake of a marginally low copper diet impairs in vitro activities of lymphocytes and neutrophils from male rats despite minimal impact on conventional indicators of copper status
    • Hopkins, R. G., and M. L. Failla. Chronic intake of a marginally low copper diet impairs in vitro activities of lymphocytes and neutrophils from male rats despite minimal impact on conventional indicators of copper status. J. Nutr. 125: 2658-2668, 1995.
    • (1995) J. Nutr. , vol.125 , pp. 2658-2668
    • Hopkins, R.G.1    Failla, M.L.2
  • 11
    • 0030803730 scopus 로고    scopus 로고
    • Biochemical characterization of the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae
    • Hung, I. H., M. Suzuki, Y. Yamaguchi, D. S. Yuan, R. D. Klausner, and J. D. Gitlin. Biochemical characterization of the Wilson disease protein and functional expression in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 272: 21461-21466, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21461-21466
    • Hung, I.H.1    Suzuki, M.2    Yamaguchi, Y.3    Yuan, D.S.4    Klausner, R.D.5    Gitlin, J.D.6
  • 12
    • 0030898098 scopus 로고    scopus 로고
    • Identification and functional expression of HAH1, a novel human gene involved in copper homeostasis
    • Klomp, L. W. J., S.-J. Lin, D. S. Yuan, R. D. Klausner, V. C. Culotta, and J. D. Gitlin. Identification and functional expression of HAH1, a novel human gene involved in copper homeostasis. J. Biol. Chem. 272: 9221-9226, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9221-9226
    • Klomp, L.W.J.1    Lin, S.-J.2    Yuan, D.S.3    Klausner, R.D.4    Culotta, V.C.5    Gitlin, J.D.6
  • 14
    • 0030910597 scopus 로고    scopus 로고
    • A role for the Saccharomyces cerevisiae ATX1 gene in copper trafficking and iron transport
    • Lin, S.-J., R. A. Pufahl, A. Dancis, T. V. O'Halloran, and V. C. Culotta. A role for the Saccharomyces cerevisiae ATX1 gene in copper trafficking and iron transport. J. Biol. Chem. 272: 9215-9220, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9215-9220
    • Lin, S.-J.1    Pufahl, R.A.2    Dancis, A.3    O'Halloran, T.V.4    Culotta, V.C.5
  • 15
    • 0028866670 scopus 로고
    • Organization of P-type ATPases: Significance of structural diversity
    • Lutsenko, S., and J. H. Kaplan. Organization of P-type ATPases: significance of structural diversity. Biochemistry 34: 15607-15613, 1995.
    • (1995) Biochemistry , vol.34 , pp. 15607-15613
    • Lutsenko, S.1    Kaplan, J.H.2
  • 16
    • 0029983378 scopus 로고    scopus 로고
    • Liver copper storage and transport during development: Implications for cytotoxicity
    • Luza, S. C., and H. C. Speisky. Liver copper storage and transport during development: implications for cytotoxicity. Am. J. Clin. Nutr. 63: 812S-820S, 1996.
    • (1996) Am. J. Clin. Nutr. , vol.63
    • Luza, S.C.1    Speisky, H.C.2
  • 17
    • 0025148186 scopus 로고
    • Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)
    • Luzio, J. P., B. Brake, G. Banting, K. E. Howell, P. Braghetta, and K. K. Stanley. Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38). Biochem. J. 270: 97-102, 1990.
    • (1990) Biochem. J. , vol.270 , pp. 97-102
    • Luzio, J.P.1    Brake, B.2    Banting, G.3    Howell, K.E.4    Braghetta, P.5    Stanley, K.K.6
  • 18
    • 0021262435 scopus 로고
    • Species differences in the occurrence of copper-metallothionein in the particulate fractions of the liver of copper-loaded animals
    • Mehra, R. K., and I. Bremner. Species differences in the occurrence of copper-metallothionein in the particulate fractions of the liver of copper-loaded animals. Biochem. J. 219: 539-546, 1984.
    • (1984) Biochem. J. , vol.219 , pp. 539-546
    • Mehra, R.K.1    Bremner, I.2
  • 19
    • 77956998789 scopus 로고
    • Isolation of Golgi apparatus
    • Morré, D. J. Isolation of Golgi apparatus. Methods Enzymol. 22: 130-148, 1971.
    • (1971) Methods Enzymol. , vol.22 , pp. 130-148
    • Morré, D.J.1
  • 21
    • 0013912521 scopus 로고
    • Metabolism of Cu-64-labeled copper by the isolated rat liver
    • Owen, C. A., Jr., and J. B. Hazelring. Metabolism of Cu-64-labeled copper by the isolated rat liver. Am. J. Physiol. 210: 1059-1064, 1966.
    • (1966) Am. J. Physiol. , vol.210 , pp. 1059-1064
    • Owen C.A., Jr.1    Hazelring, J.B.2
  • 22
    • 0032488829 scopus 로고    scopus 로고
    • Functional expression of the Menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases
    • Payne, A. S., and J. D. Gitlin. Functional expression of the Menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases. J. Biol. Chem. 273: 3765-3770, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 3765-3770
    • Payne, A.S.1    Gitlin, J.D.2
  • 23
    • 0029909937 scopus 로고    scopus 로고
    • Ligand regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: A novel mechanism of regulated trafficking
    • Petris, M. J., J. F. B. Mercer, J. G. Culvenor, P. Lockhart, P. A. Gleeson, and J. Camakaris. Ligand regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking. EMBO J. 15: 6084-6095, 1996.
    • (1996) EMBO J. , vol.15 , pp. 6084-6095
    • Petris, M.J.1    Mercer, J.F.B.2    Culvenor, J.G.3    Lockhart, P.4    Gleeson, P.A.5    Camakaris, J.6
  • 24
    • 0030787764 scopus 로고    scopus 로고
    • Genetic heterogeneity in Wilson disease: Lessons from rare alleles
    • Pyeritz, R. E. Genetic heterogeneity in Wilson disease: lessons from rare alleles. Ann. Intern. Med. 127: 70-72, 1997.
    • (1997) Ann. Intern. Med. , vol.127 , pp. 70-72
    • Pyeritz, R.E.1
  • 25
    • 0019310185 scopus 로고
    • Human fetal liver contains both zinc-and copper-rich forms of metallotheionein
    • Riordan, J. R., and V. Richards. Human fetal liver contains both zinc-and copper-rich forms of metallotheionein. J. Biol. Chem. 255: 5380-5383, 1980.
    • (1980) J. Biol. Chem. , vol.255 , pp. 5380-5383
    • Riordan, J.R.1    Richards, V.2
  • 26
    • 0025729544 scopus 로고
    • Mechanisms of copper incorporation during the biosynthesis of human ceruloplasmin
    • Sato, M., and J. D. Gitlin. Mechanisms of copper incorporation during the biosynthesis of human ceruloplasmin. J. Biol. Chem. 266: 5128-5134, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 5128-5134
    • Sato, M.1    Gitlin, J.D.2
  • 27
    • 0029928263 scopus 로고    scopus 로고
    • Wilson disease and idiopathic copper toxicosis
    • Scheinberg, I. H., and I. Sternlieb. Wilson disease and idiopathic copper toxicosis. Am. J. Clin. Nutr. 63: 842S-845S, 1996.
    • (1996) Am. J. Clin. Nutr. , vol.63
    • Scheinberg, I.H.1    Sternlieb, I.2
  • 28
    • 0029874633 scopus 로고    scopus 로고
    • Wilson disease: Genetic basis of copper toxicity, and natural history
    • Schilsky, M. L. Wilson disease: genetic basis of copper toxicity, and natural history. Semin. Liver Dis. 16: 83-95, 1996.
    • (1996) Semin. Liver Dis. , vol.16 , pp. 83-95
    • Schilsky, M.L.1
  • 29
    • 0028057852 scopus 로고
    • Liver transplantation for Wilson's disease: Indications and outcome
    • Schilsky, M. L., I. H. Scheinberg, and I. Sternlieb. Liver transplantation for Wilson's disease: indications and outcome. Hepatology 19: 583-587, 1994.
    • (1994) Hepatology , vol.19 , pp. 583-587
    • Schilsky, M.L.1    Scheinberg, I.H.2    Sternlieb, I.3
  • 30
    • 0027977547 scopus 로고
    • Pleiotropic effect of LEC mutation: A rodent model of Wilson's disease
    • Gastrointest. Liver Physlol. 29
    • Schilsky, M. L., R. J. Stockert, and I. Sternlieb. Pleiotropic effect of LEC mutation: a rodent model of Wilson's disease. Am. J. Physiol. 266 (Gastrointest. Liver Physlol. 29): G907-G913, 1994.
    • (1994) Am. J. Physiol. , vol.266
    • Schilsky, M.L.1    Stockert, R.J.2    Sternlieb, I.3
  • 31
    • 0015752890 scopus 로고
    • Preparation of rat liver cells
    • Seglen, P. O. Preparation of rat liver cells. Exp. Cell Res. 82: 391-398, 1973.
    • (1973) Exp. Cell Res. , vol.82 , pp. 391-398
    • Seglen, P.O.1
  • 32
    • 0030199612 scopus 로고    scopus 로고
    • CPX-type ATPases: A class of P-type ATPases that pump heavy metals
    • Solioz, M., and C. Vulpe. CPX-type ATPases: a class of P-type ATPases that pump heavy metals. Trends Biochem. Sci. 21: 237-241, 1996.
    • (1996) Trends Biochem. Sci. , vol.21 , pp. 237-241
    • Solioz, M.1    Vulpe, C.2
  • 36
    • 0028869945 scopus 로고
    • The Wilson disease gene: Spectrum of mutations and their consequences
    • Thomas, G. R., J. R. Forbes, E. A. Roberts, J. M. Walshe, and D. W. Cox. The Wilson disease gene: spectrum of mutations and their consequences. Nat. Genet. 9: 210-217, 1995.
    • (1995) Nat. Genet. , vol.9 , pp. 210-217
    • Thomas, G.R.1    Forbes, J.R.2    Roberts, E.A.3    Walshe, J.M.4    Cox, D.W.5
  • 37
    • 0027162649 scopus 로고
    • Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
    • Welsh, M. J., and A. E. Smith. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73: 1251-1254, 1993.
    • (1993) Cell , vol.73 , pp. 1251-1254
    • Welsh, M.J.1    Smith, A.E.2
  • 38
    • 0028001088 scopus 로고
    • The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene
    • Wu, J., J. R. Forbes, H. S. Chen, and D. W. Cox. The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene. Nat. Genet. 7: 541-454, 1994.
    • (1994) Nat. Genet. , vol.7 , pp. 541-1454
    • Wu, J.1    Forbes, J.R.2    Chen, H.S.3    Cox, D.W.4
  • 39
    • 0027431996 scopus 로고
    • Isolation and characterization of a human liver cDNA as a candidate gene for Wilson disease
    • Yamaguchi, Y., M. E. Heiny, and J. D. Gitlin. Isolation and characterization of a human liver cDNA as a candidate gene for Wilson disease. Biochem. Biophys. Res. Commun. 197: 271-277, 1993.
    • (1993) Biochem. Biophys. Res. Commun. , vol.197 , pp. 271-277
    • Yamaguchi, Y.1    Heiny, M.E.2    Gitlin, J.D.3
  • 40
    • 0028356598 scopus 로고
    • Expression of the Wilson disease gene is deficient in the Long-Evans Cinnamon rat
    • Yamaguchi, Y., M. E. Heiny, N. Shimizu, T. Aoki, and J. D. Gitlin. Expression of the Wilson disease gene is deficient in the Long-Evans Cinnamon rat. Biochem. J. 301: 1-4, 1994.
    • (1994) Biochem. J. , vol.301 , pp. 1-4
    • Yamaguchi, Y.1    Heiny, M.E.2    Shimizu, N.3    Aoki, T.4    Gitlin, J.D.5
  • 41
    • 0030467256 scopus 로고    scopus 로고
    • Biochemical characterization and intracellular localization of the Menkes disease protein
    • Yamaguchi, Y., M. E. Heiny, M. Suzuki, and J. D. Gitlin. Biochemical characterization and intracellular localization of the Menkes disease protein. Proc. Natl. Acad. Sci. USA 93: 14030-14035, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14030-14035
    • Yamaguchi, Y.1    Heiny, M.E.2    Suzuki, M.3    Gitlin, J.D.4
  • 42
    • 0030843982 scopus 로고    scopus 로고
    • Two forms of Wilson disease protein produced by alternative splicing are localized in distinct cellular compartments
    • Yang, X.-L., N. Miura, Y. Kawarada, K. Terada, K. Petrukhin, G. T. Conrad, and T. Sugiyama. Two forms of Wilson disease protein produced by alternative splicing are localized in distinct cellular compartments. Biochem. J. 326: 897-902, 1997.
    • (1997) Biochem. J. , vol.326 , pp. 897-902
    • Yang, X.-L.1    Miura, N.2    Kawarada, Y.3    Terada, K.4    Petrukhin, K.5    Conrad, G.T.6    Sugiyama, T.7
  • 43
    • 0030820818 scopus 로고    scopus 로고
    • Restriction of copper export in Saccharomyces cerevisiae to a late Golgi or post-Golgi compartment in the secretory pathway
    • Yuan, D. S., A. Dancis, and R. D. Klausner. Restriction of copper export in Saccharomyces cerevisiae to a late Golgi or post-Golgi compartment in the secretory pathway. J. Biol. Chem. 272: 25787-25793, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25787-25793
    • Yuan, D.S.1    Dancis, A.2    Klausner, R.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.