Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values

Hepatology

Volumn 37, Issue 6, 2003, Pages 1286-1292

  Mofrad, Pouneh ^a   Contos, Melissa J ^b   Haque, Mahmadul ^a   Sargeant, Carol ^a   Fisher, Robert A ^b   Luketic, Velimir A ^a   Sterling, Richard K ^a   Shiffman, Mitchell L ^a   Stravitz, Richard T ^a   Sanyal, Arun J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE;

ADULT; AGE DISTRIBUTION; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ARTICLE; CLINICAL FEATURE; COMORBIDITY; CONTROLLED STUDY; DEMOGRAPHY; ETHNIC DIFFERENCE; FEMALE; HEPATOMEGALY; HUMAN; HUMAN TISSUE; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER DISEASE; LIVER FIBROSIS; LIVER HISTOLOGY; LIVER METABOLISM; LIVER TRANSPLANTATION; LIVING DONOR; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER DISEASE; ORGAN DONOR; PHYSICAL EXAMINATION; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE;

EID: 0037566201     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2003.50229     Document Type: Article

References (17)

1. Bellentani S, Saccoccio G, Masutti F, Croce LS, Brandi G, Sasso F, Cristanini G, et al. Prevalence of and risk factors for hepatic steatosis in Northern Italy. Ann Intern Med 2000;132:112-117.
2. Wanless IR, Lentz JS. Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. HEPATOLOGY 1990;11:74-80.
3. Ground KEV. Prevalence of fatty liver in healthy adults accicientally killed. Aviat Space Environ Med 1984;55:59-61.
4. Ludwig J, Viggiano TR, McGill DB, Oh BJ. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980;55:434-438.
5. Bacon BR, Farahvash MJ, Janney CG, Neuschwander Tetri BA. Nonalcoholic steatohepatitis: an expanded clinical entity. Gastroenterology 1994;107:1103-1109.
6. Diehl AM, Goodman Z, Ishak KG. Alcoholic liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury. Gastroenterology 1988;95:1056-1062.
7. Powell EE, Cooksley WG, Hanson R, Seatle J, Halliday JW, Powell LW. The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. HEPATOLOGY 1990;11:74-80.
8. Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999;116:1413-1419.
9. Prati D, Taioli E, Zanella A, Della TE, Butelli S, Del Vecchio E, Vianello L, et al. Updated definitions of healthy ranges for serum alanine amino-transferase levels. Ann Intern Med 2002;137:1-10.
10. Contos MJ, Cales W, Luketic VA, Sterling RK, Shiffman ML, Mills AS, Fisher RA, et al. Development of nonalcoholic fatty liver disease after liver transplant for cryptogenic cirrhosis. Liver Transpl 2001;7:363-373.
11. Brunr EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999;94:2467-2474.
12. National Institutes of Health. Third report of the national cholesterol education program expert panel on detection, evaluation and treatment of high blood cholesterol in adults (Adult treatment panel III). NIH Publication 2001:1-3670.
13. Anonymous. Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. Arch Intern Med 1998;158:1855-1867.
14. Karmen A, Wroblewski F, LaDue JS. Transaminase activity in human blood. J Clin Invest 1955;34:126-133.
15. Kallei L, Hahn A, Roder VZ. Correlation between histological findings and serum transaminase values in chronic diseases of the liver. Acta Med Scand 1964;175:49-56.
16. Kaplan MM. Alanine aminotransferase levels: what's normal? Ann Intern Med 2002;137:49-51.
17. Alberti A, Morsica G, Chemello L. Hepatitis C viraemia and liver disease in symptom-free individuals with anti-HCV. Lancet 1992;340:697.