Development of new antituberculous drugs: Strategies for new drug targets and drug delivery

Drug Design Reviews Online

Volumn 2, Issue 6, 2005, Pages 427-434

  Tomioka, Haruaki ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

Antituberculous drugs; Bioinformatics; Drug delivery; Drug targets; Mycobacterium tuberculosis; Tuberculosis

Indexed keywords

1 CYCLOPROPYL 7 FLUORO 9 METHYL 8 (OCTAHYDROPYRROLO[3,4 B]PYRIDIN 6 YL) 4 OXO 3 QUINOLIZINECARBOXYLIC ACID; 1,5 BIS(4 CHLOROPHENYL) 2 METHYL 3 (4 METHYL 1 PIPERAZINYLMETHYL)PYRROLE; 2,4 DIAMINO 6 [[(3,5 DIMETHOXYPHENYL)AMINO]METHYL] 5 METHYLPYRIDO[2,3 D]PYRIMIDINE; 6,7 DIHYDRO 2 NITRO 6 (4 TRIFLUOROMETHOXYBENZYLOXY) 5H IMIDAZO[2,1 B][1,3]OXAZINE; ACETIC ACID DERIVATIVE; B 4157; B 746; CGI 17341; HYDRAZONE DERIVATIVE; ISONIAZID DERIVATIVE; LINEZOLID; LIPOSOME; N (1 TERT BUTYL 2 DIMETHYLAMINO 2 OXOETHYL) 2 (N FORMYL N HYDROXYAMINOMETHYL)HEXANAMIDE; NCX 976; OXAZOLIDINONE DERIVATIVE; PEPTIDE DEFORMYLASE INHIBITOR; PHENAZINE DERIVATIVE; PNU 100480; PURINE DERIVATIVE; PYRAN DERIVATIVE; PYRAZINAMIDE; PYRAZINOIC ACID DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDONE DERIVATIVE; PYRROLE DERIVATIVE; QUINOXALINE DERIVATIVE; SRI 3072; THIOLACTOMYCIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG TARGETING; GENETIC CODE; HUMAN; INCIDENCE; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; VIRULENCE;

EID: 24144436955     PISSN: 15672697     EISSN: None     Source Type: Journal    
DOI: 10.2174/1567269054867022     Document Type: Review

References (73)

1. Hart, C.A.; Beeching, N.J.; Duerden, B.I. J. Med. Microbiol., 1996, 44, 1-34.
2. Tiruviluamala, P.; Reichman, L.B. Annu. Rev. Public. Health, 2002, 23, 403-426.
3. Frieden, T.R.; Sterling, T.R.; Munsiff, S.S.; Watt, C.J.; Dye, C. Lancet, 2003, 362, 887-899.
4. Dye, C.; Scheele, S.; Dolin, P.; Pathania, V.; Raviglione, M.C. JAMA, 1999, 282, 677-686.
5. Aliyu, M.H.; Salihu, H.M. Wien Klin, Wochenschr., 2003, 115, 685-697.
6. Rilley, L.W. Clin. Infect. Dis., 1993, 17 (Suppl 2), S442-446.
7. McGowan, J.E. Jr. Res. Microbiol., 1993, 144, 122-128.
8. Iseman, M.D. Chemotherapy, 1999, 45 (Suppl 2), 34-40.
9. Grassi, C. Exp. Opin. Invest. Drugs, 1997, 6, 1211-1226.
10. Schraufnagel, D.E. Int. J. Tuberc. Lung Dis., 1999, 3, 651-662.
11. Tomioka, H. J. Infect. Chemother., 2000, 6, 8-20.
12. Tomioka, H. Kekkaku, 2002, 77, 573-584.
13. Chan, J.; Flynn, J. Clin. Immunol., 2004, 110, 2-12.
14. Smith, C.V.; Sharma, V.; Sacchettini, J.C. Tuberculosis (Edinb)., 2004, 84, 45-55.
15. O'Brien, R.J.; Vernon, A.A. Am. J. Respir. Crit .Care. Med., 1998, 157, 1705-1707.
16. Tomioka, H. Exp. Opin. Pharmacother., 2003, 4, 127-39.
17. Tomioka, H. Curr. Pharm. Design., 2004, 10, No. 26 (Preface).
18. Cole, S.T.; Brosch, R.; Parkhill, J.; Garnier, T.; Churcher, C.; Harris, D.; Gordon, S.V.; Eiglmeier, K.; Gas, S.; Barry, C.E. 3rd.; Tekaia, F.; Badcock, K.; Basham, D.; Brown, D.; Chillingworth, T.; Connor, R.; Davies, R.; Devlin, K.; Feltwell, T.; Gentles, S.; Hamlin, N.; Holroyd, S.; Hornsby, T.; Jagels, K.; Krogh, A.; McLean, J.; Moule, S.; Murphy, L.; Oliver, K.; Osborne, J.; Quail, M.A.; Rajandream, M.A.; Rogers, J.; Rutter, S.; Seeger, K.; Skelton, J.; Squares, R.; Squares, S.; Sulston, J.E.; Taylor, K.; Whitehead, S.; Barrell, B.G. Nature, 1998, 393, 537-544.
19. Fleischmann, R.D.; Alland, D.; Eisen, J.A.; Carpenter, L.; White, O.; Peterson, J.; DeBoy, R.; Dodson, R.; Gwinn, M.; Haft, D.; Hickey, E.; Kolonay, J.F.; Nelson, W.C.; Umayam, L.A.; Ermolaeva, M.; Salzberg, S.L.; Delcher, A.; Utterback, T.; Weidman, J.; Khouri, H.; Gill, J.; Mikula, A.; Bishai, W.; Jacobs, Jr. W, R. Jr.; Venter, J.C.; Fraser, C.M. J. Bacteriol. , 2002, 184, 5479-5490.
20. Young, D.B. Mol. Med. Today, 1997, 3, 6-7.
21. Gingeras, T.R.; Ghandour, G.; Wang, E.; Berno, A.; Small, P.M.; Drobniewski, F.; Alland, D.; Desmond, E.; Holodniy, M.; Drenkow, J. Genome Res., 1998, 8, 435-448.
22. Glickman, M.S.; Jacobs, W.R. Cell, 2001, 104, 477-485.
23. Smith, I. Clin. Microbiol. Rev., 2003, 16, 463-496.
24. Zhang, Y.; Amzel, L.M. (2002) Curr. Drug Targets, 2002, 3, 131-154.
25. Terwilliger, T.C.; Park, M.S.; Waldo, G.S.; Berendzen, J.; Hung, L.W.; Kim, C.Y.; Smith, C.V.; Sacchettini, J.C.; Bellinzoni, M.; Bossi, R.; De Rossi, E.; Mattevi, A.; Milano, A.; Riccardi, G.; Rizzi, M.; Roberts, M.M.; Coker, A.R.; Fossati, G.; Mascagni, P.; Coates, A.R.; Wood, S.P.; Goulding, C.W.; Apostol, M.I.; Anderson, D.H.; Gill, H.S.; Eisenberg, D.S.; Taneja, B.; Mande, S.; Pohl, E.; Lamzin, V.; Tucker, P.; Wilmanns, M.; Colovos, C.; Meyer-Klaucke, W.; Munro, A.W.; McLean, K.J.; Marshall, K.R.; Leys, D.; Yang, J.K.; Yoon, H.J.; Lee, B.I.; Lee, M.G.; Kwak, J.E.; Han, B.W.; Lee, J.Y.; Baek, S.H.; Suh, S.W.; Komen, M.M.; Arcus, V.L.; Baker, E.N.; Lott, J.S.; Jacobs, W. Jr.; Alber, T.; Rupp, B. Tuberculosis (Edinb)., 2003, 83, 223-249.
26. Smith, C.V.; Sharma, V.; Sacchettini, J.C. Tuberculosis (Edinb)., 2004, 84, 45-55.
27. Kantardjieff, K.; Rupp, B. (2004) Curr. Pharm. Design, 2004, 10, 3195-3211.
28. Duncan, K. Curr. Pharm. Design, 2004, 10, 3185-3194.
29. Wayne, L.G.; Lin, K.Y. Infect. Immun., 1982, 37, 1042-1049.
30. Graham, J.E.; Clark-Curtiss, J.E. Proc. Natl. Acad. Sci. USA, 1999, 96, 11554-11559.
31. Honer, Zu, Bentrup, K.; Miczak, A.; Swenson, D.L.; Russell, D.G. J. Bacteriol., 1999, 181, 7161-7167.
32. McKinney, J.D.; Honer, Zu, Bentrup, K.; Munoz-Elias, E.J.; Miczak, A.; Chen, B.; Chan, W.T.; Swenson, D.; Sacchettini, J.C.; Jacobs, W.R. Jr.; Russell, D.G. Nature, 2000, 406, 735-738.
33. Graham, J.E.; Clark-Curtiss, J.E. Proc. Natl. Acad. Sci. USA, 1999, 96, 11554-11559.
34. Smith, C.V.; Huang, C.C.; Miczak, A.; Russell, D.G.; Sacchettini, J.C.; Honerzu Bentrup, K. J. Biol. Chem., 2003, 278, 1735-1743.
35. Glickman, M.S.; Cox, J.S.; Jacobs, W.R. Jr. Mol. Cell, 2000, 5, 717-727.
36. Minnikin, D.E. In The Biology of Mycobacteria; C. Ratledge, J. Stanford, Ed.; Academic Press: San Diego, 1982; pp. 95-184.
37. Yuan, Y.; Lee, R.E.; Besra, G.S.; Belisle, J.T.; Barry, C.E. Proc. Natl. Acad. Sci. USA, 1995, 92, 6630-6634.
38. Sibley, L.D.; Hunter, S.W.; Brennan, P.J.; Krahenbuhl, J.L. Infect. Immun., 1988, 56, 1232-1236.
39. Chan, J.; Fan, X.D.; Hunter, S.W.; Brennan, P.J.; Bloom, B.R. Infect. Immun., 1991, 59, 1755-1761.
40. Cox, J.S.; Chen, B.; McNeil, M.; Jacobs, W.R. Jr. Nature, 1999, 402, 79-83.
41. Gurcha, S.S.; Baulard, A.R.; Kremer, L.; Locht, C.; Moody, D.B.; Muhlecker, W.; Costello, C.E.; Crick, D.C.; Brennan, P.J.; Besra, G.S. (2002) Biochem. J., 2002, 365, 441-450.
42. Schaeffer, M.L.; Khoo, K.H.; Besra, G.S.; Chatterjee, D.; Brennan, P.J.; Belisle, J.T.; Inamine, J.M. J. Biol. Chem., 1999, 274, 31625-31631.
43. Alexander, D.C.; Jones, J.R.; Tan, T.; Chen, J.M.; Liu, J. J. Biol. Chem., 2004, 279, 18824-18833.
44. Brennan, P.J. Tuberculosis (Edinb), 2003, 83, 91-97.
45. Ma, Y.; Stern, R.J.; Scherman, M.S.; Vissa, V.D.; Yan, W.; Jones, V.C.; Zhang, F.; Franzblau, S.G.; Lewis, W.H.; McNeil, M.R. Antimicrob. Agents Chemother., 2001, 45, 1407-1416.
46. Kantardjieff, K.A.; Kim, C.Y.; Naranjo, C.; Waldo, G.S.; Lekin, T.; Segelke, B.W.; Zemla, A.; Park, M.S.; Terwilliger, T.C.; Rupp, B. Acta. Crystallogr. D. Biol. Crystallogr., 2004, 60, 895-902
47. Pavelka, M.S. Jr.; Jacobs, W.R. Jr. J. Bacteriol., 1996, 178, 6496-6507.
48. Almrud, J.J.; Oliveira, M.A.; Kern, A.D.; Grishin, N.V.; Phillips, M.A.; Hackert, M.L. J. Mol. Biol., 2000, 295, 7-16.
49. Clements, J.M.; Beckett, R.P.; Brown, A.; Catlin, G.; Lobell, M.; Palan, S.; Thomas, W.; Whittaker, M.; Wood, S.; Salama, S.; Baker, P.J.; Rodgers, H.F.; Barynin, V.; Rice, D.W.; Hunter, M.G. Antimicrob. Agents Chemother., 2001, 45, 563-570.
50. Harth, G.; Zamecnik, P.C.; Tang, J.Y.; Tabatadze, D.; Horwitz, M.A. Proc. Natl. Acad. Sci. USA, 2000, 97, 418-423.
51. Shimizu, T.; Sato, K.; Sano, C.; Sano, K, ; Tomioka, H. Kekkaku, 2003, 78, 33-35.
52. Das, A.R.; Dattagupta, N.; Sridhar, C.N.; Wu, W.K. Scand. J. Infect. Dis., 2003, 35, 168-174.
53. Tomioka, H.; Saito, H.; Sato, K.; Yoneyama, T. Am. Rev. Respir. Dis., 1991, 144, 575-579.
54. Bermudez, L.E. Immunobiology, 1994, 191:578-583.
55. Kansal, R.G.; Gomez-Flores, R.; Sinha, I.; Mehta, R.T. Antimicrob. Agents Chemother., 1997, 41, 17-23..
56. Barrow, W.W. Rev. Sci. Tech., 2001, 20, 55-70.
57. Khuller, G.K.; Kapur, M.; Sharma, S. Curr. Pharm. Design, 2004, 10, 3263-3274.
58. Orozco, L.C.; Quintana, F.O.; Beltran, R.M.; de Moreno, I.; Wasserman, M.; Rodriguez, G. Tubercle, 1986, 67, 91-97.
59. Agarwal, A.; Kandpal, H.; Gupta, H.P.; Singh, N.B.; Gupta, C.M. Antimicrob. Agents Chemother., 1994, 38, 588-593.
60. Deol, P.; Khuller, G.K.; Joshi, K. Antimicrob. Agents Chemother., 1997, 41, 1211-1214.
61. Adams, L.B.; Sinha, I.; Franzblau, S.G.; Krahenbuhl, J.L.; Mehta, R.T. Antimicrob. Agents Chemother., 1999, 43, 1638-1643.
62. Dhillon, J.; Fielding, R.; Adler-Moore, J.; Goodall, R.L.; Mitchison, D. J. Antimicrob. Chemother., 2001, 48, 869-876.
63. Whitehead, T.C.; Lovering, A.M.; Cropley, I.M.; Wade, P.; Davidson, R.N. Eur. J. Clin. Microbiol. Infect. Dis., 1998, 17, 794-797.
64. Donald, P.R.; Sirgel, F.A.; Venter, A.; Smit, E.; Parkin, D.P.; Van de Wal, B.W.; Mitchison, D.A. J. Antimicrob. Chemother., 2001, 48, 877-880.
65. Barrow, E.L.; Winchester, G.A.; Staas, J.K.; Quenelle, D.C.; Barrow, W.W. Antimicrob. Agents Chemother., 1998, 42, 2682-2689.
66. Quenelle, D.C.; Staas, J.K.; Winchester, G.A.; Barrow, E.L.; Barrow, W.W. Antimicrob. Agents Chemother., 1999, 43, 1144-1151.
67. Quenelle, D.C.; Winchester, G.A.; Staas, J.K.; Barrow, E.L.; Barrow, W.W. Antimicrob. Agents Chemother., 2001, 45, 1637-1644.
68. Dutt, M.; Khuller, G.K. Antimicrob. Agents Chemother., 2001, 45, 363-366.
69. Dutt, M.; Khuller, G.K. J. Antimicrob. Chemother., 2001, 47, 829-835.
70. Suarez, S.; O'Hara, P.; Kazantseva, M.; Newcomer, C.E.; Hopfer, R.; McMurray, D.N.; Hickey, A.J. Pharm. Res., 2001, 18, 1315-1319.
71. Barrow, W.W. Curr. Pharm. Design, 2004, 10, 3275-3284.
72. Pandey, R.; Khuller, G.K. J. Antimicrob. Chemother., 2004, 53, 635-40.
73. Schumann, G.; Mollmann, U. Antimicrob. Agents Chemother., 2001, 45, 1317-1322.